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Volumn 10, Issue 2, 2007, Pages 145-152

Biomedical research tools from the seabed

Author keywords

Biomedical research tool; Cone shell toxin; Conotoxin; Intracellular signaling; Ion channel; Marine natural product; Membrane processes

Indexed keywords

AETX K; AM 336; AMPHILECTENE DERIVATIVE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; BOLINAQUINONE; CALCIUM CHANNEL; CEPHALOSTATIN 1; CGX 1160; CONANTOKIN G; CONOTOXIN; CURACIN A; CYCLOAMPHILECTENE DERIVATIVE; CYCLOPRODIGIOSIN; EPITAONDIOL; LATRUNCULIN A; LO 959; OMEGA CONOTOXIN MVIIA; PACIFENOL; PROSTAGLANDIN SYNTHASE INHIBITOR; PSAMMAPLIN A; PYRIDINIUM DERIVATIVE; SESQUITERPENE; SMENOSPONGIDINE; SMENOSPONGINE; SMENOSPONGORINE; STYPOTRIOL TRIACETATE; TRIGONELLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VARIOLIN B;

EID: 33947326627     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (49)
  • 2
    • 18844452208 scopus 로고    scopus 로고
    • Battershill C, Long P, Jaspars M: Marine biodiscovery: New drugs from the ocean depths. Biologist (2005) 52(2):107-114. An excellent general introduction to the field of marine natural products and their applications as well as major issues facing the field of marine biodiscovery.
    • Battershill C, Long P, Jaspars M: Marine biodiscovery: New drugs from the ocean depths. Biologist (2005) 52(2):107-114. An excellent general introduction to the field of marine natural products and their applications as well as major issues facing the field of marine biodiscovery.
  • 3
    • 17844399025 scopus 로고    scopus 로고
    • Natural products to drugs: Natural product derived compounds in clinical trials
    • Butler MS: Natural products to drugs: Natural product derived compounds in clinical trials. (2005) Nat Prod Rep 22(2):162-195.
    • (2005) Nat Prod Rep , vol.22 , Issue.2 , pp. 162-195
    • Butler, M.S.1
  • 4
    • 4344650390 scopus 로고    scopus 로고
    • Newman DJ, Cragg GM: Marine natural products and related compounds in clinical and advanced preclinical trials. J Nat Prod (2004) 67(8):1216-1238. A review which details the status of small-molecule therapeutics of marine origin in clinical and preclinical trials.
    • Newman DJ, Cragg GM: Marine natural products and related compounds in clinical and advanced preclinical trials. J Nat Prod (2004) 67(8):1216-1238. A review which details the status of small-molecule therapeutics of marine origin in clinical and preclinical trials.
  • 5
    • 11144353441 scopus 로고    scopus 로고
    • Visegrady B, Lorinczy D, Hild G, Somogyi B, Nyitrai M: A simple model for the cooperative stabilisation of actin filaments by phalloidin and jasplakinolide. FEBS Lett (2005) 579(1):6-10. An outstanding example of the use of a sponge natural product to investigate fundamental processes within the cell.
    • Visegrady B, Lorinczy D, Hild G, Somogyi B, Nyitrai M: A simple model for the cooperative stabilisation of actin filaments by phalloidin and jasplakinolide. FEBS Lett (2005) 579(1):6-10. An outstanding example of the use of a sponge natural product to investigate fundamental processes within the cell.
  • 6
    • 0347989461 scopus 로고    scopus 로고
    • Conus venoms: A rich source of novel ion channel-targeted peptides
    • Terlau H, Olivera BM: Conus venoms: A rich source of novel ion channel-targeted peptides. (2004) Physiol Rev 84(1):41-68.
    • (2004) Physiol Rev , vol.84 , Issue.1 , pp. 41-68
    • Terlau, H.1    Olivera, B.M.2
  • 7
    • 27944475132 scopus 로고    scopus 로고
    • Fluorescent proteins as a toolkit for in vivo imaging
    • Chudakov DM, Lukyanov S, Lukyanov KA: Fluorescent proteins as a toolkit for in vivo imaging. Trends Biotechnol (2005) 23(12):605-613.
    • (2005) Trends Biotechnol , vol.23 , Issue.12 , pp. 605-613
    • Chudakov, D.M.1    Lukyanov, S.2    Lukyanov, K.A.3
  • 9
    • 0042490898 scopus 로고    scopus 로고
    • Irreversible and reversible pore formation by polymeric alkylpyridinium salts (poly-APS) from the sponge Reniera sarai
    • McClelland D, Evans RM, Abidin I, Sharma S, Choudhry FZ, Jaspars M, Sepcic K, Scott RH: Irreversible and reversible pore formation by polymeric alkylpyridinium salts (poly-APS) from the sponge Reniera sarai. Br J Pharmacol (2003) 139(8):1399-1408.
    • (2003) Br J Pharmacol , vol.139 , Issue.8 , pp. 1399-1408
    • McClelland, D.1    Evans, R.M.2    Abidin, I.3    Sharma, S.4    Choudhry, F.Z.5    Jaspars, M.6    Sepcic, K.7    Scott, R.H.8
  • 10
    • 0041704812 scopus 로고    scopus 로고
    • Tucker SJ, McClelland D, Jaspars M, Sepcic K, MacEwan DJ, Scott RH: The influence of alkyl pyridinium sponge toxins on membrane properties, cytotoxicity, transfection and protein expression in mammalian cells. Biochim Biophys Acta Biomembr (2003) 1614(2):171-181. The application of transient membrane pores to deliver cDNA into cells. This is the first example of the use of pores to deliver genetic material.
    • Tucker SJ, McClelland D, Jaspars M, Sepcic K, MacEwan DJ, Scott RH: The influence of alkyl pyridinium sponge toxins on membrane properties, cytotoxicity, transfection and protein expression in mammalian cells. Biochim Biophys Acta Biomembr (2003) 1614(2):171-181. The application of transient membrane pores to deliver cDNA into cells. This is the first example of the use of pores to deliver genetic material.
  • 11
    • 33646129207 scopus 로고    scopus 로고
    • Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: Distinct tools for intracellular delivery of cDNA and siRNA
    • McLaggan D, Adjimatera N, Sepçiç K, Jaspars M, MacEwan DJ, Blagbrough IS, Scott RH: Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: Distinct tools for intracellular delivery of cDNA and siRNA. BMC Biotechnol (2006) 6:6.
    • (2006) BMC Biotechnol , vol.6 , pp. 6
    • McLaggan, D.1    Adjimatera, N.2    Sepçiç, K.3    Jaspars, M.4    MacEwan, D.J.5    Blagbrough, I.S.6    Scott, R.H.7
  • 12
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • Zasloff M: Antimicrobial peptides of multicellular organisms. Nature (2002) 415(6870):389-395.
    • (2002) Nature , vol.415 , Issue.6870 , pp. 389-395
    • Zasloff, M.1
  • 13
    • 2542454628 scopus 로고    scopus 로고
    • Synthesis and bioactivity of linear oligomers related to polymeric alkylpyridinium metabolites from the Mediterranean sponge Reniera sarai
    • Mancini I, Sicurelli A, Guella G, Turk T, Maček P, Sepčić K: Synthesis and bioactivity of linear oligomers related to polymeric alkylpyridinium metabolites from the Mediterranean sponge Reniera sarai. Org Biomol Chem (2004) 2(9):1368-1375.
    • (2004) Org Biomol Chem , vol.2 , Issue.9 , pp. 1368-1375
    • Mancini, I.1    Sicurelli, A.2    Guella, G.3    Turk, T.4    Maček, P.5    Sepčić, K.6
  • 14
    • 0032547244 scopus 로고    scopus 로고
    • Selective entry to the dimeric or oligomeric pyridinium sponge macrocycles via aminopentadienal derivatives. Possible biogenetic relevance with manzamine alkaloids
    • Kaiser A, Billot X, Gateau-Olesker A, Marazano C, Das BC: Selective entry to the dimeric or oligomeric pyridinium sponge macrocycles via aminopentadienal derivatives. Possible biogenetic relevance with manzamine alkaloids. J Am Chem Soc (1998) 120(32):8026-8034.
    • (1998) J Am Chem Soc , vol.120 , Issue.32 , pp. 8026-8034
    • Kaiser, A.1    Billot, X.2    Gateau-Olesker, A.3    Marazano, C.4    Das, B.C.5
  • 16
    • 33645393913 scopus 로고    scopus 로고
    • Llewellyn L: Saxitoxin, a toxic marine natural product that targets a multitude of receptors. Nat Prod Rep (2006) 23(2):200-222. A review on saxitoxin and its analogs and their many biological activities, as viewed from an ecological context. Their interaction with known and proposed receptors is discussed.
    • Llewellyn L: Saxitoxin, a toxic marine natural product that targets a multitude of receptors. Nat Prod Rep (2006) 23(2):200-222. A review on saxitoxin and its analogs and their many biological activities, as viewed from an ecological context. Their interaction with known and proposed receptors is discussed.
  • 17
    • 22544467754 scopus 로고    scopus 로고
    • The neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons
    • LePage KT, Goeger D, Yokokawa F, Asano T, Shioiri T, Gerwick WH, Murray TF: The neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons. Toxicol Lett (2005) 158(2):133-139.
    • (2005) Toxicol Lett , vol.158 , Issue.2 , pp. 133-139
    • LePage, K.T.1    Goeger, D.2    Yokokawa, F.3    Asano, T.4    Shioiri, T.5    Gerwick, W.H.6    Murray, T.F.7
  • 19
    • 15444362099 scopus 로고    scopus 로고
    • Conus peptides - a rich pharmaceutical treasure
    • Wang CZ, Chi CW: Conus peptides - a rich pharmaceutical treasure. Acta Biochim Biophys Sin (Shanghai) (2004) 36(11):713-723.
    • (2004) Acta Biochim Biophys Sin (Shanghai) , vol.36 , Issue.11 , pp. 713-723
    • Wang, C.Z.1    Chi, C.W.2
  • 20
    • 33747666931 scopus 로고    scopus 로고
    • Identification of a novel class of nicotinic receptor antagonists - dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum
    • Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ: Identification of a novel class of nicotinic receptor antagonists - dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. J Biol Chem (2006) 281(34):24745-24755.
    • (2006) J Biol Chem , vol.281 , Issue.34 , pp. 24745-24755
    • Loughnan, M.1    Nicke, A.2    Jones, A.3    Schroeder, C.I.4    Nevin, S.T.5    Adams, D.J.6    Alewood, P.F.7    Lewis, R.J.8
  • 21
    • 33746516663 scopus 로고    scopus 로고
    • Rauck R, Wallace M, Leong M, MineHart M, Webster L, Charapata S, Abraham J, Buffington D, Ellis D, Kartzinel R: A randomized, double-blind, placebo-controlled study of intrathecal ziconotide in adults with severe chronic pain. J Pain Symptom Manage (2006) 31(5):393-406. The results of the clinical trial of ziconotide that resulted in its approval for the treatment of chronic pain. This treatment is the first of its kind to be approved from a marine origin. Current investigations into conotoxins will undoubtedly lead to treatments for other types of pain.
    • Rauck R, Wallace M, Leong M, MineHart M, Webster L, Charapata S, Abraham J, Buffington D, Ellis D, Kartzinel R: A randomized, double-blind, placebo-controlled study of intrathecal ziconotide in adults with severe chronic pain. J Pain Symptom Manage (2006) 31(5):393-406. The results of the clinical trial of ziconotide that resulted in its approval for the treatment of chronic pain. This treatment is the first of its kind to be approved from a marine origin. Current investigations into conotoxins will undoubtedly lead to treatments for other types of pain.
  • 22
    • 20444477528 scopus 로고    scopus 로고
    • A toxin against pain
    • Stix G: A toxin against pain. Sci Am (2005) 292(4):70-75.
    • (2005) Sci Am , vol.292 , Issue.4 , pp. 70-75
    • Stix, G.1
  • 23
    • 33750957742 scopus 로고    scopus 로고
    • Livett BG, Sandall DW, Keays D, Down J, Gayler KR, Satkunanathan N, Khalil Z: Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor. Toxicon (2006) 48(7):810- 829. A review that discusses the current treatments derived from conotoxins which are in, or nearing, clinical evaluation.
    • Livett BG, Sandall DW, Keays D, Down J, Gayler KR, Satkunanathan N, Khalil Z: Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor. Toxicon (2006) 48(7):810- 829. A review that discusses the current treatments derived from conotoxins which are in, or nearing, clinical evaluation.
  • 24
    • 33750086364 scopus 로고    scopus 로고
    • Characterization of contryphans from Conus loroisii and Conus amadis that target calcium channels
    • Sabareesh V, Gowd KH, Ramasamy P, Sudarslal S, Krishnan KS, Sikdar SK, Balaram P: Characterization of contryphans from Conus loroisii and Conus amadis that target calcium channels. Peptides (2006) 27(11):2647-2654.
    • (2006) Peptides , vol.27 , Issue.11 , pp. 2647-2654
    • Sabareesh, V.1    Gowd, K.H.2    Ramasamy, P.3    Sudarslal, S.4    Krishnan, K.S.5    Sikdar, S.K.6    Balaram, P.7
  • 25
    • 33748154073 scopus 로고    scopus 로고
    • Isolation and cDNA cloning of a potassium channel peptide toxin from the sea anemone Anemonia erythraea
    • Hasegawa Y, Honma T, Nagai H, Ishida M, Nagashima Y, Shiomi K: Isolation and cDNA cloning of a potassium channel peptide toxin from the sea anemone Anemonia erythraea. Toxicon (2006) 48(5):536-542.
    • (2006) Toxicon , vol.48 , Issue.5 , pp. 536-542
    • Hasegawa, Y.1    Honma, T.2    Nagai, H.3    Ishida, M.4    Nagashima, Y.5    Shiomi, K.6
  • 27
    • 15944409599 scopus 로고    scopus 로고
    • Block of voltage-gated potassium channels by Pacific ciguatoxin-1 contributes to increased neuronal excitability in rat sensory neurons
    • Birinyi-Strachan LC, Gunning SJ, Lewis RJ, Nicholson GM: Block of voltage-gated potassium channels by Pacific ciguatoxin-1 contributes to increased neuronal excitability in rat sensory neurons. Toxicol Appl Pharmacol (2005) 204(2):175-186.
    • (2005) Toxicol Appl Pharmacol , vol.204 , Issue.2 , pp. 175-186
    • Birinyi-Strachan, L.C.1    Gunning, S.J.2    Lewis, R.J.3    Nicholson, G.M.4
  • 28
    • 31344464433 scopus 로고    scopus 로고
    • Acute actions of marine toxin latrunculin A on the electrophysiological properties of cultured dorsal root ganglion neurones
    • Houssen WE, Jaspars M, Wease KN, Scott RH: Acute actions of marine toxin latrunculin A on the electrophysiological properties of cultured dorsal root ganglion neurones. Comp Biochem Physiol C Toxicol Pharmacol (2006) 142(1-2):19-29.
    • (2006) Comp Biochem Physiol C Toxicol Pharmacol , vol.142 , Issue.1-2 , pp. 19-29
    • Houssen, W.E.1    Jaspars, M.2    Wease, K.N.3    Scott, R.H.4
  • 29
    • 33749260724 scopus 로고    scopus 로고
    • F-actin-based Ca signalling - a critical comparison with the current concept of Ca signaling
    • Lange K, Gartzke J: F-actin-based Ca signalling - a critical comparison with the current concept of Ca signaling. J Cell Physiol (2006) 209(2):270-287.
    • (2006) J Cell Physiol , vol.209 , Issue.2 , pp. 270-287
    • Lange, K.1    Gartzke, J.2
  • 30
    • 33747202181 scopus 로고    scopus 로고
    • A pyridinium derivative from Red Sea soft corals inhibited voltage-activated potassium conductances and increased excitability of rat cultured sensory neurones
    • Temraz TA, Houssen WE, Jaspars M, Woolley DR, Wease KN, Davies SN, Scott RH: A pyridinium derivative from Red Sea soft corals inhibited voltage-activated potassium conductances and increased excitability of rat cultured sensory neurones. BMC Pharmacol (2006) 6:10.
    • (2006) BMC Pharmacol , vol.6 , pp. 10
    • Temraz, T.A.1    Houssen, W.E.2    Jaspars, M.3    Woolley, D.R.4    Wease, K.N.5    Davies, S.N.6    Scott, R.H.7
  • 31
    • 33745761029 scopus 로고    scopus 로고
    • Chemistry and biology of anti-inflammatory marine natural products: Molecules interfering with cyclooxygenase, NF-κB and other unidentified targets
    • Terracciano S, Aquino M, Rodriquez M, Monti MC, Casapullo A, Riccio R, Gomez-Paloma L: Chemistry and biology of anti-inflammatory marine natural products: Molecules interfering with cyclooxygenase, NF-κB and other unidentified targets. Curr Med Chem (2006) 13(16):1947-1969.
    • (2006) Curr Med Chem , vol.13 , Issue.16 , pp. 1947-1969
    • Terracciano, S.1    Aquino, M.2    Rodriquez, M.3    Monti, M.C.4    Casapullo, A.5    Riccio, R.6    Gomez-Paloma, L.7
  • 32
    • 0000949932 scopus 로고    scopus 로고
    • Rovirosa J, Sepulveda M, Quezada E, San-martin A: Isoepitaondiol, a diterpenoid of Stypopodium flabelliforme and the insecticidal activity of stypotriol, epitaondiol and derivatives. Phytochemistry (1992) 31(8):2679-2681.
    • Rovirosa J, Sepulveda M, Quezada E, San-martin A: Isoepitaondiol, a diterpenoid of Stypopodium flabelliforme and the insecticidal activity of stypotriol, epitaondiol and derivatives. Phytochemistry (1992) 31(8):2679-2681.
  • 33
    • 0343803549 scopus 로고
    • Antimicrobial activity of halogenated sesquiterpenes of Laurencia claviformis from Easter Island
    • Rovirosa J, Astudillo L, Sanchez I, Palacios Y, Sanmartin A: Antimicrobial activity of halogenated sesquiterpenes of Laurencia claviformis from Easter Island. Bol Soc Chil Quim (1989) 34:147-152.
    • (1989) Bol Soc Chil Quim , vol.34 , pp. 147-152
    • Rovirosa, J.1    Astudillo, L.2    Sanchez, I.3    Palacios, Y.4    Sanmartin, A.5
  • 34
    • 33745327057 scopus 로고    scopus 로고
    • 2 inactivation by bolinaquinone. Chembiochem (2006) 7(6):971-980. Fundamental insight into the mechanism of action of phospholipase A2.
    • 2 inactivation by bolinaquinone. Chembiochem (2006) 7(6):971-980. Fundamental insight into the mechanism of action of phospholipase A2.
  • 36
    • 33845936028 scopus 로고    scopus 로고
    • Lopez-Anton N, Rudy A, Barth N, Schmitz LM, Pettit GR, Schulze-Osthoff K, Dirsch VM, Vollmar AM: The marine product cephalostatin 1 activates an endoplasmic reticulum stress-specific and apoptosome-independent apoptotic signaling pathway. J Biol Chem (2006) 281(44):33078-33086. Insight into the mode of action of the extraordinarily toxic marine metabolite cephalostatin 1 see also reference [37•].
    • Lopez-Anton N, Rudy A, Barth N, Schmitz LM, Pettit GR, Schulze-Osthoff K, Dirsch VM, Vollmar AM: The marine product cephalostatin 1 activates an endoplasmic reticulum stress-specific and apoptosome-independent apoptotic signaling pathway. J Biol Chem (2006) 281(44):33078-33086. Insight into the mode of action of the extraordinarily toxic marine metabolite cephalostatin 1 (see also reference [37•].
  • 37
    • 17844364586 scopus 로고    scopus 로고
    • Muller IM, Dirsch VM, Rudy A, Lopez-Anton N, Pettit GR, Vollmar AM: Cephalostatin 1 inactivates Bcl-2 by hyperphosphorylation independent of M-phase arrest and DNA damage. Mol Pharmacol (2005) 67(5):1684-1689. Further insight into the mode of action of the extraordinarily toxic marine metabolite cephalostatin 1 see also reference [36•].
    • Muller IM, Dirsch VM, Rudy A, Lopez-Anton N, Pettit GR, Vollmar AM: Cephalostatin 1 inactivates Bcl-2 by hyperphosphorylation independent of M-phase arrest and DNA damage. Mol Pharmacol (2005) 67(5):1684-1689. Further insight into the mode of action of the extraordinarily toxic marine metabolite cephalostatin 1 (see also reference [36•].
  • 38
    • 33744500224 scopus 로고    scopus 로고
    • Bioassay for the identification of natural product-based activators of peroxisome proliferator-activated receptor-? (PPAR?): The marine sponge metabolite psammaplin A activates PPAR? and induces apoptosis in human breast tumor cells
    • Mora FD, Jones DK, Desai PV, Patny A, Avery MA, Feller DR, Smillie T, Zhou YD, Nagle DG: Bioassay for the identification of natural product-based activators of peroxisome proliferator-activated receptor-? (PPAR?): The marine sponge metabolite psammaplin A activates PPAR? and induces apoptosis in human breast tumor cells. J Nat Prod (2006) 69(4):547-552.
    • (2006) J Nat Prod , vol.69 , Issue.4 , pp. 547-552
    • Mora, F.D.1    Jones, D.K.2    Desai, P.V.3    Patny, A.4    Avery, M.A.5    Feller, D.R.6    Smillie, T.7    Zhou, Y.D.8    Nagle, D.G.9
  • 40
    • 16644395180 scopus 로고    scopus 로고
    • Sesquiterpene aminoquinones, from a marine sponge, induce erythroid differentiation in human chronic myelogenous leukemia, K562 cells
    • Aoki S, Kong D, Matsui K, Rachmat R, Kobayashi M: Sesquiterpene aminoquinones, from a marine sponge, induce erythroid differentiation in human chronic myelogenous leukemia, K562 cells. Chem Pharm Bull (2004) 52(8):935-937.
    • (2004) Chem Pharm Bull , vol.52 , Issue.8 , pp. 935-937
    • Aoki, S.1    Kong, D.2    Matsui, K.3    Rachmat, R.4    Kobayashi, M.5
  • 43
    • 33749059234 scopus 로고    scopus 로고
    • Actin-targeting natural products: Structures, properties, and mechanisms of action
    • Allingham JS, Klenchin VA, Rayment I: Actin-targeting natural products: Structures, properties, and mechanisms of action. Cell Mol Life Sci (2006) 63(18):2119-2134.
    • (2006) Cell Mol Life Sci , vol.63 , Issue.18 , pp. 2119-2134
    • Allingham, J.S.1    Klenchin, V.A.2    Rayment, I.3
  • 44
    • 85123225136 scopus 로고    scopus 로고
    • Petchprayoon C, Stuwanborirux K, Tanaka JI, Yan Y, Sakata T, Marriott G: Fluorescent kabiramides: New probes to quantify actin in vitro and in vivo. Bioconjug Chem (2005) 16(6):1382- 1389. The synthesis and use of a number of fluorescent probes based around kabiramide C. These will be extremely valuable in the analysis of actin content in vitro and in vivo.
    • Petchprayoon C, Stuwanborirux K, Tanaka JI, Yan Y, Sakata T, Marriott G: Fluorescent kabiramides: New probes to quantify actin in vitro and in vivo. Bioconjug Chem (2005) 16(6):1382- 1389. The synthesis and use of a number of fluorescent probes based around kabiramide C. These will be extremely valuable in the analysis of actin content in vitro and in vivo.
  • 45
    • 23044525153 scopus 로고    scopus 로고
    • Bioluminescent and red-fluorescent lures in a deep-sea siphonophore
    • Haddock SH, Dunn CW, Pugh PR, Schnitzler CE: Bioluminescent and red-fluorescent lures in a deep-sea siphonophore. Science (2005) 309(5732):263.
    • (2005) Science , vol.309 , Issue.5732 , pp. 263
    • Haddock, S.H.1    Dunn, C.W.2    Pugh, P.R.3    Schnitzler, C.E.4
  • 46
    • 0032052229 scopus 로고    scopus 로고
    • The origins of marine bioluminescence: Turning oxygen defence mechanisms into deep-sea communication tools
    • Rees JF, de Wergifosse B, Noiset O, Dubuisson M, Janssens B, Thompson EM: The origins of marine bioluminescence: Turning oxygen defence mechanisms into deep-sea communication tools. J Exp Biol 1998, 201(Pt 8):1211-1221.
    • (1998) J Exp Biol , vol.201 , Issue.PART 8 , pp. 1211-1221
    • Rees, J.F.1    de Wergifosse, B.2    Noiset, O.3    Dubuisson, M.4    Janssens, B.5    Thompson, E.M.6
  • 48
    • 19444376373 scopus 로고    scopus 로고
    • Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues
    • Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K: Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues. Biochem Biophys Res Commun (2005) 332(2):392-397.
    • (2005) Biochem Biophys Res Commun , vol.332 , Issue.2 , pp. 392-397
    • Maeda, H.1    Hosokawa, M.2    Sashima, T.3    Funayama, K.4    Miyashita, K.5
  • 49
    • 33947305167 scopus 로고    scopus 로고
    • ASSOCIATES OF CAPE COD INC (Wainwright NR, Novitsky TJ): Endotoxin binding and neutralizing protein and uses thereof. US-06384200 (2002).
    • ASSOCIATES OF CAPE COD INC (Wainwright NR, Novitsky TJ): Endotoxin binding and neutralizing protein and uses thereof. US-06384200 (2002).


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