Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery

Journal of Computer-Aided Molecular Design

Volumn 21, Issue 1-3, 2007, Pages 121-130

  Stewart, Kent D ^a   Steffy, Kevin ^a   Harris, Kevin ^a   Harlan, John E ^a   Stoll, Vincent S ^a   Huth, Jeffrey R ^a   Walter, Karl A ^a   Gramling Evans, Emily ^a   Mendoza, Renaldo R ^a   Severin, Jean M ^a   Richardson, Paul L ^a   Barrett, Leo W ^a   Matayoshi, Edmund D ^a   Swift, Kerry M ^a   Betz, Stephen F ^a   Muchmore, Steve W ^a   Kempf, Dale J ^a   Molla, Akhter ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

gp41 Protein; Human immunodeficiency virus (HIV); Protein design; Protein engineering

Indexed keywords

DISEASES; VIRUSES;

AMINO-ACIDS; BINDING POCKETS; DRUG DISCOVERY; GP41 PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS-1; N TERMINUS; PROTEIN DESIGN; PROTEIN ENGINEERING;

PROTEINS;

GLYCOPROTEIN GP 41;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CENTRIFUGATION; CRYSTALLOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS 1; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SEDIMENTATION; SPECTROSCOPY; STRUCTURAL PROTEOMICS;

EID: 33947276831     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-007-9107-1     Document Type: Article

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