The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 9, 2000, Pages 2219-2227

  Zhou, Genfa ^a,b   Ferrer, Marc ^b   Chopra, Rajiv ^b   Kapoor, Tarun M ^c   Strassmaier, Tim ^d   Weissenhorn, Winfried ^e   Skehel, John J ^f   Oprian, Dan ^d   Schreiber, Stuart L ^b,c   Harrison, Stephen C ^a,b   Wiley, Don C ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRANDEIS UNIVERSITY   (United States)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

^f NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; GLYCOPROTEIN GP 41; SYNTHETIC PEPTIDE;

ARTICLE; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DRUG DESIGN; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; LIGAND BINDING; MEMBRANE FUSION; PROTEIN FOLDING; STRUCTURE ACTIVITY RELATION; VIRUS CELL INTERACTION; X RAY CRYSTALLOGRAPHY;

ANTI-HIV AGENTS; BINDING SITES; COMBINATORIAL CHEMISTRY TECHNIQUES; CRYSTALLOGRAPHY, X-RAY; HIV ENVELOPE PROTEIN GP41; HIV-1; INHIBITORY CONCENTRATION 50; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; PEPTIDES; PROTEIN BINDING;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 17944384967     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00155-3     Document Type: Article

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