Impaired Endothelial Function in Healthy African-American Adolescents Compared with Caucasians

Journal of Pediatrics

Volumn 150, Issue 4, 2007, Pages 400-406

  Duck, Mary M ^a   Hoffman, Robert P ^b,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b Division of Endocrinology   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; AFRICAN AMERICAN; ARTERY OCCLUSION; ARTICLE; BODY MASS; CAUCASIAN; CELL FUNCTION; COMPARATIVE STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; FEMALE; FOREARM BLOOD FLOW; GLUCOSE TOLERANCE TEST; HUMAN; INSULIN RESPONSE; INSULIN SENSITIVITY; MALE; NORMAL HUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PUBERTY; RACE DIFFERENCE;

ADOLESCENT; AFRICAN AMERICANS; BODY MASS INDEX; CHILD; CHOLESTEROL; ENDOTHELIUM, VASCULAR; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; MALE; PUBERTY; REGRESSION ANALYSIS; VASCULAR DISEASES;

EID: 33947268080     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2006.12.034     Document Type: Article

References (39)

1. Alderman M.H., Cohen H.W., and Madhavan S. Myocardial infarction in treated hypertensive patients: the paradox of lower incidence but higher mortality in young blacks compared with whites. Circulation 101 (2000) 1109-1114
2. Manhapra A., Canto J.G., Vaccarino V., Parsons L., Kiefe C.I., Barron H.V., et al. Relation of age and race with hospital death after acute myocardial infarction. Am Heart J 148 (2004) 92-98
3. Ferdinand K.C., and Clark L.T. The epidemic of diabetes mellitus and the metabolic syndrome in African Americans. Rev Cardiovasc Med 5 suppl 3 (2004) S28-S33
4. Williams J.E., Massing M., Rosamond W.D., Sorlie P.D., and Tyroler H.A. Racial disparities in CHD mortality from 1968-1992 in the state economic areas surrounding the ARIC study communities. Atherosclerosis Risk in Communities. Ann Epidemiol 9 (1999) 472-480
5. Kissela B., Schneider A., Kleindorfer D., Khoury J., Miller R., Alwell K., et al. Stroke in a biracial population: the excess burden of stroke among blacks. Stroke 35 (2004) 426-431
6. Yang D., Howard G., Coffey C.S., and Roseman J. The confounding of race and geography: how much of the excess stroke mortality among African Americans is explained by geography?. Neuroepidemiology 23 (2004) 118-122
7. Macaluso C.J., Bauer U.E., Deeb L.C., Malone J.I., Chaudhari M., Silverstein J., et al. Type 2 diabetes mellitus among Florida children and adolescents, 1994 through 1998. Pub Health Rep 117 (2002) 373-379
8. McBean A.M., Li S., Gilbertson D.T., and Collins A.J. Differences in diabetes prevalence, incidence, and mortality among the elderly of four racial/ethnic groups: whites, blacks, Hispanics, and Asians. Diabetes Care 27 (2004) 2317-2324
9. Evans R.R., Phillips B.G., Singh G., Bauman J.L., and Gulati A. Racial and gender differences in endothelin-1. Am J Cardiol 78 (1996) 486-488
10. Perregaux D., Chauduri A., Rao S., Airen A., Wilson M., Sung B.H., et al. Brachial vascular reactivity in blacks. Hypertens 36 (2000) 866-871
11. Hinderliter A.L., Sager A.R., Sherwood A., Light K.C., Gridler S.S., and Willis P.W. Ethnic differences in forearm vasodilator capacity. Am J Cardiolol 78 (1996) 208-211
12. Hinderliter A.L., Blumenthal J.A., Waugh R., Chlukuri M., and Sherwood A. Ethnic differences in left ventricular structure: relations to hemodynamics and diurnal blood pressure variation. Am J Hypertens 17 (2004) 43-49
13. Vita J.A., and Keany Jr. J.F. Hormone replacement therapy and endothelial function: the exception that proves the rule?. Arterioscler Thromb Vasc Biol 21 (2004) 1867-1869
14. Lange L.A., Bowden D.W., Langefeld C.D., Wagenknecht L.E., Carr J.J., Rich S.S., et al. Heritability of carotid artery intima-medial thickness in type 2 diabetes. Stroke 33 (2002) 1876-1881
15. Serne E.H., Gans R.O.B., ter Maaten J.C., ter Wee P.M., Donker A.J.M., and Stehouwer C.D.A. Capillary recruitment is impaired in essential hypertension and relates to insulin's metabolic and vascular actions. Cardiovascular Res 49 (2001) 161-168
16. Serne E.H., Stehouwer C.D.A., ter Maaten J.C., ter Wee P.M., Rauwerda D.A., Donker A.J., et al. Microvascular function relates to insulin sensitivity and blood pressure in normal subjects. Circulation 99 (1999) 896-902
17. Petrie J.R., Ueda S., Webb D.J., Elliott H.L., and Connell J.M. Endothelial nitric oxide production and insulin sensitivity. A physiologic link with implications for pathogeneisis of cardiovascular disease. Circulation 33 (1996) 1331-1333
18. Arslanian S., and Suprasongsin C. Differences in the in vivo insulin sectretion and sensitivity in healthy black versus white adolescents. J Pediatr 229 (1996) 440-443
19. Arslanian S., Suprasongsin C., and Janosky J.E. Insulin secretion and sensitivity in black versus white prepubertal healthy children. J Clin Endocrinol Metab 82 (1997) 1923-1927
20. Cook J.S., Hoffman R.P., Stene M.A., and Hansen J.R. Effects of maturational stage on insulin sensitivity during puberty. J Clin Endocrinol Metab 77 (1993) 725-730
21. Uehata A., Lieberman E.H., Gerhard M.D., Anderson T.J., Ganz P., Polak J.F., et al. Non invasive assessment of endothelium dependent flow-mediated dilation in the brachial artery. Vasc Med 2 (1997) 87-92
22. Higashi Y., and Yoshizumi M. New methods to evaluate endothelial function: method for assessing endothelial function in humans using a strain-gauge plethysmography: nitric oxide-dependent and -independent vasodilation. J Pharmacol Sci 93 (2003) 399-404
23. Singhal A., Jamison N., Fewtrell M., Deanfield J., Lucas A., and Sattar N. Adiponectin predicts insulin resistance but not endothelial function in healthy young adults. J Clin Endocrinol Metab 90 (2005) 4615-4621
24. Dagre A., Lekakis J., Mihas C., Protgerou A., Thalassinou L., Tryhonopoulus D., et al. Association of dehydroepiandrosterone-sulfate with endothelial function in young women with polycystic ovary syndrome. Eur J Endocrinol 154 (2006) 883-890
25. Hoffman R.P., and Armstrong P.T. Glucose effectiveness, peripheral and hepatic insulin sensitivity in obese and lean prepubertal children. Int J Obes Relat Metab Disord 20 (1996) 521-525
26. Hoffman R.P., Vicini P., Sivitz W.I., and Cobelli C. Pubertal adolescent male-female differences in insulin sensitivity and glucose effectiveness determined by the one compartment minimal model. Pediatr Res 48 (2000) 384-388
27. Steele R. Use of C14-glucose to measure hepatic glucose production following an I.Vglucose load or after injection of insulin. Metabolism 8 (1959) 512-519
28. Nekummet K.M., Goble M.M., Young R.B., Kaplowitz P.B., and Schiekin R.M. Altered blood pressure reactivity in adolescent diabetics. Pediatrics 93 (1994) 616-621
29. Serne E.H., Gans R.O.B., ter Maaten J.C., ter Wee P.M., Donker A.J.M., and Stehouwer C.D.A. Capillary recruitment is impaired in essential hypertension and relates to insulin's metabolic and vascular actions. Cardiovascular Res 49 (2001) 161-168
30. Laakso M., Edelman S.V., Brechtel G., and Baron A.D. Decreased effect of insulin to stimulate skeletal muscle blood flow in obese men. J Clin Invest 85 (1990) 1844-1852
31. Anderson E.A., Hoffman R.P., Balon T.W., Sinkey C.A., and Mark A.L. Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 87 (1991) 2246-2252
32. Steinberg H.O., Brechtel G., Johnson A., Fineberg N., and Baron A.D. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. J Clin Invest 94 (1994) 1172-1179
33. Svec F., Nastasi K., Hilton C., Bao W., Srinivasan S., and Berenson G.S. Black-white contrasts in insulin levels during pubertal development: the Bogalusa heart Study. Diabetes 41 (1992) 313-317
34. Schuster D.P., Kien C.L., and Osei K. Differential impact of obesity on glucose metabolism in black and white American adolescents. Am J Med Sci 316 (1998) 361-367
35. Arslanian S.A., Saad R., Lewy V., Danadian K., and Janosky J. Hyperinsulinemia in African-American children: decreased insulin clearance and increased insulin secretion and its relationship to insulin sensitivity. Diabetes 51 (2002) 3014-3019
36. Goran M.I., Bergman R.N., Cruz M.L., and Watanabe R. Insulin resistance and associated compensatory responses in African-American and Hispanic Children. Diabetes Care 25 (2002) 2184-2190
37. Preeyasombat C., Bacchetti P., Lazar A.A., and Lustig R.H. Racial and etiopathologic dichotomies in insulin hypersecretion and resistance in obese children. J Pediatr 146 (2005) 474-481
38. Arslanian S.A., Hiel B.V., Becker D.J., and Drash A.L. Sexual dimorphism in insulin sensitivity in adolescents with insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 72 (1991) 920-926
39. Hashimoto M., Akishita M., Eto M., Ishikawa M., Kozaki K., Toba K., et al. Modulation of endothelium-dependent flow mediated dilation of the brachial artery by sex and menstrual cycle. Circulation 92 (1995) 3431-3435