A genome-wide linkage scan for quantitative trait loci underlying obesity related phenotypes in 434 Caucasian families

Human Genetics

Volumn 121, Issue 1, 2007, Pages 145-148

  Zhao, Lan Juan ^a,b   Xiao, Peng ^a   Liu, Yong Jun ^b   Xiong, Dong Hai ^a   Shen, Hui ^b   Recker, Robert R ^a   Deng, Hong Wen ^b,c,d  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^c XI'AN JIAOTONG UNIVERSITY   (China)

^d HUNAN NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BODY FAT; CAUCASIAN; CHROMOSOME 10P; CHROMOSOME 17Q; CHROMOSOME 20P; CHROMOSOME 5Q; CHROMOSOME 8Q; CONTROLLED STUDY; FAMILY; FEMALE; GENETIC LINKAGE; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; OBESITY; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS MAPPING; SEX DIFFERENCE;

EUROPEAN CONTINENTAL ANCESTRY GROUP; FAMILY; FEMALE; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); MALE; OBESITY; PHENOTYPE; QUANTITATIVE TRAIT LOCI;

EID: 33947245930     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-006-0286-y     Document Type: Article

References (12)

1. Almasy L, Blangero J (1998) Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198-1211
2. Deng HW, Deng H, Liu YJ, Liu YZ, Xu FH, Shen H, Conway T, Li JL, Huang QY, Davies KM, Recker RR (2002) A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet 70:1138-1151
3. Feitosa MF, Borecki IB, Rich SS, Arnett DK, Sholinsky P, Myers RH, Leppert M, Province MA (2002) Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: The National Heart, Lung, and Blood Institute Family Heart Study. Am J Hum Genet 70:72-82
4. Gorlova OY, Amos CI, Wang NW, Shete S, Turner ST, Boerwinkle E (2003) Genetic linkage and imprinting effects on body mass index in children and young adults. Eur J Hum Genet 11:425-432
5. Kopelman PG (2000) Obesity as a medical problem. Nature 404:635-643
6. Lander E, Kruglyak L (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247
7. Liu YJ, Araujo S, Recker RR, Deng HW (2003) Molecular and genetic mechanisms of obesity: Implications for future management. Curr Mol Med 3:325-340
8. Livshits G, Yakovenko K, Ginsburg E, Kobyliansky E (1998) Genetics of human body size and shape: Pleiotropic and independent genetic determinants of adiposity. Ann Hum Biol 25:221-236
9. Perusse L, Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B, Snyder EE, Bouchard C (2005) The human obesity gene map: The 2004 update. Obes Res 13:381-490
10. Platte P, Papanicolaou GJ, Johnston J, Klein CM, Doheny KF, Pugh EW, Roy-Gagnon MH, Stunkard AJ, Francomano CA, Wilson AF (2003) A study of linkage and association of body mass index in the Old Order Amish. Am J Med Genet C Semin Med Genet 121:71-80
11. Rice T, Perusse L, Bouchard C, Rao DC (1999) Familial aggregation of body mass index and subcutaneous fat measures in the longitudinal Quebec family study. Genet Epidemiol 16:316-334
12. Rocha JL, Eisen EJ, Van Vleck LD, Pomp D (2004) A large-sample QTL study in mice: II. Body composition. Mamm Genome 15:100-113