Green tea polyphenols reduce autoimmune symptoms in a murine model for human Sjogren's syndrome and protect human salivary acinar cells from TNF-a-induced cytotoxicity

Autoimmunity

Volumn 40, Issue 2, 2007, Pages 138-147

  Hsu, Stephen D ^a   Dickinson, Douglas P ^a   Qin, Haiyan ^a   Borke, James ^a   Ogbureke, Kalu U E ^a   Winger, Julia N ^a   Camba, Amy M ^a   Bollag, Wendy B ^a   Stöppler, Hubert J ^a   Sharawy, Mohamed M ^a   Schuster, George S ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Acinar cells; EGCG; Green tea polyphenols; MAPK; Sjogren's syndrome

Indexed keywords

AUTOANTIBODY; EPIGALLOCATECHIN GALLATE; GREEN TEA EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; POLYPHENOL DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ACINAR CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; ENZYME ACTIVATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PROTEIN PHOSPHORYLATION; SJOEGREN SYNDROME; SUBMANDIBULAR GLAND;

ANIMALS; AUTOIMMUNITY; CATECHIN; CELL LINE; CELL SURVIVAL; DISEASE MODELS, ANIMAL; FLAVONOIDS; HUMANS; IMIDAZOLES; LYMPHOCYTES; MAP KINASE KINASE 4; MAP KINASE KINASE KINASES; MICE; MICE, INBRED NOD; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOLS; PHOSPHORYLATION; PLANT EXTRACTS; PYRIDINES; SALIVARY GLANDS; SJOGREN'S SYNDROME; TEA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33947215079     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.1080/08916930601167343     Document Type: Article

References (53)

1. Daniels, TE and Wu, AJ (2000) Xerostomia - clinical evaluation and treatment in general practice. J Calif Dent Assoc, 28, pp. 933-941.
2. Fox, RI (1997) Sjögren's syndrome. Controversies and progress. Clin Lab Med, 17, pp. 431-444.
3. Vitali, C. Bombardieri, S. Jonsson, R. Moutsopoulos, HM, Alexander, EL, Carsons, SE, Daniels, TE, Fox, PC, Fox, RI, Kassan, SS, Pillemer, SR, Talal, N. and Weisman, MH (2002) European study group on classification criteria for Sjogren's syndrome. Classification criteria for Sjogren's syndrome: A revised version of the European criteria proposed by the American-European consensus group. Ann Rheum Dis, 61, pp. 554-558.
4. Kang, HI, Fei, HM, Saito, I., Sawada, S., Chen, SL, Chan, E., Peebles, C., Bugawan, TL and Erlich, HA (1993) Comparison of HLA class II genes in Caucasoid, Chinese, and Japanese patients with primary Sjögren's syndrome. J Immunol, 150, pp. 3615-3623.
5. Carsons, S. (2001) A review and update of Sjogren's syndrome: Manifestations, diagnosis, and treatment. Am J Manag Care, 7:14, pp. S433-S434.
6. Zhang, N. (1995) Epidemiological study of primary Sjogrne's syndrome in China. Chin Med J (Engl), 108, pp. 787-788.
7. Yoshida, S. (1999) Sjögren's syndrome. Nippon Rinsho, 57, pp. 360-363.
8. Miyasaka, N. (1995) Epidemiology and pathogenesis of Sjögren's syndrome. Nippon Rinsho, 53, pp. 2367-2370.
9. Ikebe, K., Nokubi, T., Sajima, H., Kobayashi, S., Hata, K., Ono, T. and Ettinger, RL (2001) Perception of dry mouth in a sample of community-dwelling older adults in Japan. Spec Care Dentist, 21, pp. 52-59.
10. Schein, OD, Hochberg, MC, Munoz, B., Tielsch, JM, Bandeen-Roche, K. Provost, T., Anhalt, GJ and West, S. (1999) Dry eye and dry mouth in the elderly: A population-based assessment. Arch Intern Med, 159, pp. 1359-1363.
11. Billings, RJ, Proskin, HM and Moss, ME (1996) Xerostomia and associated factors in a community-dwelling adult population. Community Dent Oral Epidemiol, 24, pp. 312-316.
12. Baudouin, C., Pisella, PJ and Brignole, F. (2004) Current treatments of xerophthalmia in Sjögren's syndrome. Rev Med Int, 25, pp. 376-382.
13. Fox, PC (2004) Salivary enhancement therapies. Caries Res, 38, pp. 241-246.
14. Khurshudian, AV (2003) A pilot study to test the efficacy of oral administration of interferon-alpha lozenges to patients with Sjögren's syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 95, pp. 38-44.
15. Ohno, S., Suzuki, T. and Dohi, Y. (1990) The effect of bakumondo-to on salivary secretion in Sjogren syndrome. Ryumachi, 30, pp. 10-16.
16. Zhao, LJ, Li, ZJ, Huang, YY, Ti, ZK and Chen, Y. (1989) Experience on 60 cases of Sjogren's syndrome diagnosed and treated with traditional Chinese medicine. J Tradit Chin Med, 9, pp. 31-34.
17. Mukhtar, H. and Ahmad, N. (2000) Tea polyphenols: Prevention of cancer and optimizing health. Am J Clin Nutr, 71:6, pp. 1698S-1702S.
18. Yang, CS, Maliakal, P. and Meng, X. (2002) Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol, 42, pp. 25-54.
19. Katiyar, SK and Elmets, CA (2001) Green tea polyphenolic antioxidants and skin photoprotection (review). Int J Oncol, 18, pp. 1307-1313.
20. Cabrera, C., Artacho, R. and Gimenez, R. (2006) Beneficial effects of green tea - a review. J Am Coll Nutr, 25, pp. 79-99.
21. Sueoka, N., Suganuma, M., Sueoka, E., Okabe, S., Matsuyama, S., Imai, K., Nakachi, K. and Fujiki, H. (2001) A new function of green tea: Prevention of lifestyle-related diseases. Ann NY Acad Sci, 928, pp. 274-280.
22. Hsu, S. and Dickinson, D. (2006) Green tea: A new approach to managing oral manifestations of Sjogren's syndrome and skin manifestations of lupus. J Biochem Mol Biol, 39, pp. 229-239.
23. Hsu, S., Dickinson, D., Qin, H., Lapp, C., Lapp, D., Borke, J., Walsh, DS, Bollag, WB, Stoppler, H., Yamamoto, T., Osaki, T. and Schuster, G. (2005) Inhibition of autoantigen expression by (-) -epigallocatechin-3-gallate (the major constituent of green tea) in normal human cells. J Pharmacol Exp Ther, 315, pp. 805-811.
24. Yamamoto, T., Hsu, S., Lewis, J., Wataha, J., Dickinson, D., Singh, B., Bollag, WB, Lockwood, P., Ueta, E., Osaki, T. and Schuster, G. (2003) Green tea polyphenol causes differential oxidative environments in tumor versus normal epithelial cells. J Pharmacol Exp Ther, 307, pp. 230-236.
25. Suganuma, M. Sueoka, E., Sueoka, N., Okabe, S. and Fujiki, H. (2000) Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-alpha expression. Biofactors, 13, pp. 67-72.
26. Fujiki, H., Suganuma, M., Kurusu, M., Okabe, S., Imayoshi, Y., Taniguchi, S. and Yoshida, T. (2003) New TNF-alpha releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen. Mutat Res, 523, pp. 119-125.
27. Balasubramanian, S., Efimova, T. and Eckert, RL (2002) Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes. J Biol Chem, 277, pp. 1828-1836.
28. Yang, CS, Lee, MJ and Chen, L. (1999) Human salivary tea catechin levels and catechin esterase activities: Implication in human cancer prevention studies. Cancer Epidemiol Biomarkers Prev, 8, pp. 83-89.
29. Cha, S., Peck, AB and Humphreys-Beher, MG (2002) Progress in understanding autoimmune exocrinopathy using the non-obese diabetic mouse: An update. Crit Rev Oral Biol Med, 13, pp. 4-16.
30. Morbini, P., Manzo, A., Caporali, R., Epis, O., Villa, C., Tinelli, C., Solcia, E. and Montecucco, C. (2005) Multilevel examination of minor salivary gland biopsy for Sjogren's syndrome significantly improves diagnostic performance of AECG classification criteria. Arthritis Res Ther, 7, pp. R343-R348.
31. Azuma, M., Tamatani, T., Kasai, Y. and Sato, M. (1993) Immortalization of normal human salivary gland cells with duct-, myoepithelial-, acinar-, or squamous phenotype by transfection with SV40 ori-mutant deoxyribonucleic acid. Lab Invest, 69, pp. 24-42.
32. Guggenbuhl, P., Veillard, E., Quelvenec, E., Jego, P., Semana, G., Jean, S., Meadeb, J., Chales, G. and Perdriger, A. (2000) Analysis of TNFalpha microsatellites in 35 patients with primary Sjogren's syndrome. Joint Bone Spine, 67, pp. 290-295.
33. Koski, H., Janin, A., Humphreys-Beher, MG, Sorsa, T., Malmstrom, M. and Konttinen, YT (2001) Tumor necrosis factor-alpha and receptors for it in labial salivary glands in Sjogren's syndrome. Clin Exp Rheumatol, 19, pp. 131-137.
34. Kulkarni, K., Selesniemi, K. and Brown, TL (2006) Interferon-gamma sensitizes the human salivary gland cell line, HSG, to tumor necrosis factor-alpha induced activation of dual apoptotic pathways. Apoptosis
35. Yamamoto, T., Staples, J., Wataha, J., Lewis, J., Lockwood, P., Schoenlein, P., Rao, S., Osaki, T., Dickinson, D., Kamatani, T., Schuster, G. and Hsu, S. (2004) Protective effects of EGCG on salivary gland cells treated with gamma-radiation or cis-platinum(II)diammine dichloride. Anticancer Res, 24, pp. 3065-3073.
36. Kim, HP, Wang, X., Zhang, J., Suh, GY, Benjamin, IJ, Ryter, SW and Choi, AM (2005) Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: Involvement of p38 beta MAPK and heat shock factor-1. J Immunol, 175, pp. 2622-2629.
37. Liu, J. and Lin, A. (2005) Role of JNK activation in apoptosis: A double-edged sword. Cell Res, 15, pp. 36-42.
38. Lin, A. (2003) Activation of the JNK signaling pathway: Breaking the brake on apoptosis. Bioessays, 25, pp. 17-24.
39. Curtis, CL, Harwood, JL, Dent, CM and Caterson, B. (2004) Biological basis for the benefit of nutraceutical supplementation in arthritis. Drug Discov Today, 9, pp. 165-172.
40. Mikuls, TR, Cerhan, JR, Criswell, LA, Merlino, L., Mudano, AS, Burma, M., Folsom, AR and Saag, KG (2002) Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: Results from the Iowa women's health study. Arthritis Rheum, 46, pp. 83-91.
41. Haqqi, TM, Anthony, DD, Gupta, S., Ahmad, N., Lee, MS, Kumar, GK and Mukhtar, H. (1999) Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea. Proc Natl Acad Sci USA, 96, pp. 4524-4529.
42. Roca V, Rosignoli F, Calafat M, Leiros CP. Lack of nitric oxide-mediated regulation of amylase secretion stimulated by VIP in parotid glands of NOD mice. Int Immunopharmacol, 4, pp. 1837-1844.
43. Yang, F., de Villiers, WJ, McClain, CJ and Varilek, GW (1998) Green tea polyphenols block endotoxin-induced tumor necrosis factor-production and lethality in a murine model. J Nutr, 128, pp. 2334-2340.
44. Sayama, K., Oguni, I., Tsubura, A., Tanaka, S. and Matsuzawa, A. (2003) Inhibitory effects of autoimmune disease by green tea in MRL-Faslprcg/ Faslprcg mice. In Vivo, 17, pp. 545-552.
45. Slomiany, BL and Slomiany, A. (2002) Porphyromonas gingivalis lipopolysaccharide interferes with salivary mucin synthesis through inducible nitric oxide synthase activation by ERK and p38 kinase. Biochem Biophys Res Commun, 297, pp. 1149-1153.
46. Zentner, MD, Lin, HH, Wen, X., Kim, KJ and Ann, DK (1998) The amiloride-sensitive epithelial sodium channel alpha-subunit is transcriptionally down-regulated in rat parotid cells by the extracellular signal-regulated protein kinase pathway. J Biol Chem, 273, pp. 30770-30776.
47. Slomiany, BL and Slomiany, A. (2002) Nitric oxide interferes with salivary mucin synthesis: Involvement of ERK and p38 mitogen-activated protein kinase. Physiol Pharmacol, 53, pp. 325-336.
48. Brautigam, VM, Frasier, C., Nikodemova, M. and Watters, JJ (2005) Purinergic receptor modulation of BV-2 microglial cell activity: Potential involvement of p38 MAP kinase and CREB. J Neuroimmunol, 166, pp. 113-125.
49. Nakamura, H., Kawakami, A., Yamasaki, S., Kawabe, Y., Nakamura, T. and Eguchi, K. (1999) Expression of mitogen activated protein kinases in labial salivary glands of patients with Sjogren's syndrome. Ann Rheum Dis, 58, pp. 382-385.
50. Morin, CI and Huot, J. (2004) Recent advances in stress signaling in cancer. Cancer Res, 64, pp. 1893-1898.
51. Vayalil, PK, Elmets, CA and Katiyar, SK (2003) Treatment of green tea polyphenols in hydrophilic cream prevents UVB-induced oxidation of lipids and proteins, depletion of antioxidant enzymes and phosphorylation of MAPK proteins in SKH-1 hairless mouse skin. Carcinogenesis, 24, pp. 927-936.
52. Bubici, C., Papa, S., Pham, CG, Zazzeroni, F. and Franzoso, G. (2004) NF-kappaB and JNK: An intricate affair. Cell Cycle, 3, pp. 1524-1529.
53. Nakano, H. Nakajima, A., Sakon-Komazawa, S. Piao, JH, Xue, X. and Okumura, K. (2006) Reactive oxygen species mediate crosstalk between NF-kappaB and JNK. Cell Death Differ, 13, pp. 730-737.