Fibroblast growth factor-2 maintains the differentiation potential of nucleus pulposus cells in vitro: Implications for cell-based transplantation therapy

Spine

Volumn 32, Issue 5, 2007, Pages 495-502

  Tsai, Tsung Ting ^a,b   Guttapalli, Asha ^a   Oguz, Erbil ^a,c   Chen, Lih Huei ^b   Vaccaro, Alexander R ^a   Albert, Todd J ^a   Shapiro, Irving M ^a   Risbud, Makarand V ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

Culture expansion; Differentiation; Fibroblast growth factor 2; Gene expression; Nucleus pulposus cells

Indexed keywords

ALGINIC ACID; COLLAGEN TYPE 1; COLLAGEN TYPE 2; FIBROBLAST GROWTH FACTOR 2; FIBROMODULIN; GELATINASE A; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA1; VERSICAN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CELL TRANSPLANTATION; CONTROLLED STUDY; GENE EXPRESSION; IMMOBILIZED CELL; NONHUMAN; NUCLEUS PULPOSUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS;

AGGRECANS; ANIMALS; CATTLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CELL TRANSPLANTATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; HIGH MOBILITY GROUP PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERVERTEBRAL DISK; MATRIX METALLOPROTEINASE 2; MICROFILAMENTS; PHENOTYPE; PROTEOGLYCANS; RNA, MESSENGER; SMAD PROTEINS; SPINAL DISEASES; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA1; TRANSPLANTATION, AUTOLOGOUS;

EID: 33947181438     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/01.brs.0000257341.88880.f1     Document Type: Article

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