-
1
-
-
0027243086
-
The proto-oncogene Bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
-
Allsopp TE, Wyatt S, Paterson HF, Davies AM (1993) The proto-oncogene Bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73:295-307
-
(1993)
Cell
, vol.73
, pp. 295-307
-
-
Allsopp, T.E.1
Wyatt, S.2
Paterson, H.F.3
Davies, A.M.4
-
3
-
-
0026454763
-
Prevention of programmed cell death of sympathetic neurons by the Bcl-2 proto-oncogene
-
Garcia I, Martinou I, Tsujimoto Y, Martinou J-C (1992) Prevention of programmed cell death of sympathetic neurons by the Bcl-2 proto-oncogene. Science 258:302-304
-
(1992)
Science
, vol.258
, pp. 302-304
-
-
Garcia, I.1
Martinou, I.2
Tsujimoto, Y.3
Martinou, J.-C.4
-
4
-
-
0026781986
-
Bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs
-
Miyashita T, Reed JC (1992) Bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res 52:5407-5411
-
(1992)
Cancer Res
, vol.52
, pp. 5407-5411
-
-
Miyashita, T.1
Reed, J.C.2
-
5
-
-
0033179760
-
Bcl-2 family members and the mitochondria in apoptosis
-
Gross AJ, McDonnell M, Korsmeyer SJ (1999) Bcl-2 family members and the mitochondria in apoptosis. Genes Dev 13:1899-1911
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.J.1
McDonnell, M.2
Korsmeyer, S.J.3
-
6
-
-
0035026438
-
Anti-apoptotic proteins. The Bcl-2 and inhibitor of apoptosis protein families
-
Deveraux QL, Schendel SL, Reed JC (2001) Anti-apoptotic proteins. The Bcl-2 and inhibitor of apoptosis protein families. Cardiol Clin 19:57-74
-
(2001)
Cardiol Clin
, vol.19
, pp. 57-74
-
-
Deveraux, Q.L.1
Schendel, S.L.2
Reed, J.C.3
-
7
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko LJ, Prives C (1996) p53: puzzle and paradigm. Genes Dev 10:1054-1072
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
8
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ (1997) p53, the cellular gatekeeper for growth and division. Cell 88:323-331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
9
-
-
0030046508
-
Life, death, and the pursuit of apoptosis
-
White E (1996) Life, death, and the pursuit of apoptosis. Genes Dev 10:1-15
-
(1996)
Genes Dev
, vol.10
, pp. 1-15
-
-
White, E.1
-
10
-
-
0035825595
-
A transcriptional activation function of p53 is dispensible for and inhibitory of its apoptotic function
-
Kokontis JM, Wagner AJ, O'Leary M, Liao S, Hay N (2001) A transcriptional activation function of p53 is dispensible for and inhibitory of its apoptotic function. Oncogene 20:659-668
-
(2001)
Oncogene
, vol.20
, pp. 659-668
-
-
Kokontis, J.M.1
Wagner, A.J.2
O'Leary, M.3
Liao, S.4
Hay, N.5
-
11
-
-
0029092356
-
Induction of apoptosis in HeLa cells by transactivation deficient p53
-
Haupt Y, Rowan S, Shaulian E, Vousden KH, Oren M (1995) Induction of apoptosis in HeLa cells by transactivation deficient p53. Genes Dev 9:2170-2183
-
(1995)
Genes Dev
, vol.9
, pp. 2170-2183
-
-
Haupt, Y.1
Rowan, S.2
Shaulian, E.3
Vousden, K.H.4
Oren, M.5
-
12
-
-
33947152117
-
Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion
-
Moll UM, Riou G, Levine AJ (1995) Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci USA 92:4407-4411
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4407-4411
-
-
Moll, U.M.1
Riou, G.2
Levine, A.J.3
-
13
-
-
0030924724
-
Cytoplasmic p53 polypeptide is associated with ribosomes
-
Fontoura BM, Atienza CA, Sorokina EA, Morimoto T, Carroll RB (1997) Cytoplasmic p53 polypeptide is associated with ribosomes. Mol Cell Biol 17:3146-3154
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3146-3154
-
-
Fontoura, B.M.1
Atienza, C.A.2
Sorokina, E.A.3
Morimoto, T.4
Carroll, R.B.5
-
14
-
-
0027984448
-
Hormonal carcinogenesis in breast cancer: Cellular and molecular studies of malignant progression
-
Clarke R, Skaar T, Baumann K et al (1994) Hormonal carcinogenesis in breast cancer: cellular and molecular studies of malignant progression. Breast Cancer Res Treat 31:237-248
-
(1994)
Breast Cancer Res Treat
, vol.31
, pp. 237-248
-
-
Clarke, R.1
Skaar, T.2
Baumann, K.3
-
16
-
-
0029157380
-
Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells
-
Teixeira C, Reed JC, Pratt MA (1995) Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells. Cancer Res 55:3902-3907
-
(1995)
Cancer Res
, vol.55
, pp. 3902-3907
-
-
Teixeira, C.1
Reed, J.C.2
Pratt, M.A.3
-
17
-
-
0028115802
-
Bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer
-
Leek RD, Kaklamanis L, Pezzella F, Gatter KC, Harris AL (1994) Bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer. Br J Cancer 69:135-139
-
(1994)
Br J Cancer
, vol.69
, pp. 135-139
-
-
Leek, R.D.1
Kaklamanis, L.2
Pezzella, F.3
Gatter, K.C.4
Harris, A.L.5
-
18
-
-
0027993895
-
Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity
-
Bhargava V, Kell DL, van de Rijn M, Warnke RA (1994) Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity. Am J Pathol 145:535-540
-
(1994)
Am J Pathol
, vol.145
, pp. 535-540
-
-
Bhargava, V.1
Kell, D.L.2
van de Rijn, M.3
Warnke, R.A.4
-
19
-
-
0027286622
-
A negative regulatory element in the Bcl-2 5′-untranslated region inhibits expression from an upstream promoter
-
Young RL, Korsmeyer SJ (1993) A negative regulatory element in the Bcl-2 5′-untranslated region inhibits expression from an upstream promoter. Mol Cell Biol 13:3686-3697
-
(1993)
Mol Cell Biol
, vol.13
, pp. 3686-3697
-
-
Young, R.L.1
Korsmeyer, S.J.2
-
20
-
-
0033527753
-
Mechanisms of transcriptional activation of Bcl-2 gene expression by 17beta-estradiol in breast cancer cells
-
Dong L, Wang W, Wang F et al (1999) Mechanisms of transcriptional activation of Bcl-2 gene expression by 17beta-estradiol in breast cancer cells. J Biol Chem 274:32099-32107
-
(1999)
J Biol Chem
, vol.274
, pp. 32099-32107
-
-
Dong, L.1
Wang, W.2
Wang, F.3
-
21
-
-
0033621962
-
17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing Bcl-2 expression via two estrogen-responsive elements present in the coding sequence
-
Perillo B, Sasso A, Abbondanza C, Palumbo G (2000) 17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing Bcl-2 expression via two estrogen-responsive elements present in the coding sequence. Mol Cell Biol 20:2890-2901
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2890-2901
-
-
Perillo, B.1
Sasso, A.2
Abbondanza, C.3
Palumbo, G.4
-
22
-
-
0028230596
-
Down-regulation of Bcl-2 by p53 in breast cancer cells
-
Haldar S, Negrini M, Monne M, Sabbioni S, Croce CM (1994) Down-regulation of Bcl-2 by p53 in breast cancer cells. Cancer Res 54:2095-2097
-
(1994)
Cancer Res
, vol.54
, pp. 2095-2097
-
-
Haldar, S.1
Negrini, M.2
Monne, M.3
Sabbioni, S.4
Croce, C.M.5
-
23
-
-
0028292480
-
Identification of a p53-dependent negative response element in the Bcl-2 gene
-
Miyashita T, Harigai M, Hanada M, Reed JC (1994) Identification of a p53-dependent negative response element in the Bcl-2 gene. Cancer Res 54:3131-3135
-
(1994)
Cancer Res
, vol.54
, pp. 3131-3135
-
-
Miyashita, T.1
Harigai, M.2
Hanada, M.3
Reed, J.C.4
-
24
-
-
0029670144
-
A cis-acting element in the BCL-2 gene controls expression through translational mechanisms
-
Harigai M, Miyashita T, Hanada M, Reed JC (1996) A cis-acting element in the BCL-2 gene controls expression through translational mechanisms. Oncogene 12:1369-1374
-
(1996)
Oncogene
, vol.12
, pp. 1369-1374
-
-
Harigai, M.1
Miyashita, T.2
Hanada, M.3
Reed, J.C.4
-
25
-
-
0026660339
-
Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens
-
Crook T, Vousden KH (1992) Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens. EMBO J 1:3935-3940
-
(1992)
EMBO J
, vol.1
, pp. 3935-3940
-
-
Crook, T.1
Vousden, K.H.2
-
26
-
-
0027980357
-
Interaction of p53 with MDM2 is independent of E6 and does not mediate wild type transformation suppressor function
-
Marston N J, Crook T, Vousden KH (1994) Interaction of p53 with MDM2 is independent of E6 and does not mediate wild type transformation suppressor function. Oncogene 9:2707-2716
-
(1994)
Oncogene
, vol.9
, pp. 2707-2716
-
-
Marston, N.J.1
Crook, T.2
Vousden, K.H.3
-
27
-
-
0037689113
-
Comparison of p53 mutational status with mRNA and protein expression in a panel of 24 breast carcinoma cell lines
-
Concin N, Zeillinger C, Tong D et al (2003) Comparison of p53 mutational status with mRNA and protein expression in a panel of 24 breast carcinoma cell lines. Breast Can Res Treat 79:37-46
-
(2003)
Breast Can Res Treat
, vol.79
, pp. 37-46
-
-
Concin, N.1
Zeillinger, C.2
Tong, D.3
-
28
-
-
0032422126
-
Estrogen withdrawal-induced human breast cancer tumour regression in nude mice is prevented by Bcl-2
-
Pratt MA, Krajewski S, Menard M, Krajewska M, Macleod H, Reed JC (1998) Estrogen withdrawal-induced human breast cancer tumour regression in nude mice is prevented by Bcl-2. FEBS Lett 440:403-408
-
(1998)
FEBS Lett
, vol.440
, pp. 403-408
-
-
Pratt, M.A.1
Krajewski, S.2
Menard, M.3
Krajewska, M.4
Macleod, H.5
Reed, J.C.6
-
29
-
-
0028575705
-
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19 kDa protein or the cellular Bcl-2 protein
-
Shen Y, Shenk T (1994) Relief of p53-mediated transcriptional repression by the adenovirus E1B 19 kDa protein or the cellular Bcl-2 protein. Proc Natl Acad Sci USA 91:8940-8944
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8940-8944
-
-
Shen, Y.1
Shenk, T.2
-
30
-
-
0037349289
-
p53 has a direct apoptogenic role at the mitochondria
-
Mihara M, Erster S, Zaika A et al (2003) p53 has a direct apoptogenic role at the mitochondria. Mol Cell 11:577-590
-
(2003)
Mol Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
-
31
-
-
0030865104
-
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
-
O'Connor PM, Jackman J, Bae I et al (1997) Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res 57:4285-4300
-
(1997)
Cancer Res
, vol.57
, pp. 4285-4300
-
-
O'Connor, P.M.1
Jackman, J.2
Bae, I.3
-
32
-
-
0035843156
-
Negative regulation of Bcl-2 expression by p53 in hematopoietic cells
-
Wu Y-I, Mehew JW, Heckman CA, Arcinas M, Boxer LM (2001) Negative regulation of Bcl-2 expression by p53 in hematopoietic cells. Oncogene 20:240-251
-
(2001)
Oncogene
, vol.20
, pp. 240-251
-
-
Wu, Y.-I.1
Mehew, J.W.2
Heckman, C.A.3
Arcinas, M.4
Boxer, L.M.5
-
33
-
-
0028335717
-
Tumor suppressor p53 is a regulator of Bcl-2 and bax gene expression in vitro and in vivo
-
Miyashita T, Krajewski S, Krajewska M et al (1994) Tumor suppressor p53 is a regulator of Bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9:1799-1805
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
-
34
-
-
0033598352
-
Adenovirus-mediated transfer of wild-type p53 gene sensitizes TNF resistant MCF-7 derivatives to the cytotoxic effect of this cytokine: Relationship with c-myc and Rb
-
Ameyar M, Shatrov V, Bouquet C et al (1999) Adenovirus-mediated transfer of wild-type p53 gene sensitizes TNF resistant MCF-7 derivatives to the cytotoxic effect of this cytokine: relationship with c-myc and Rb. Oncogene 18:5464-5472
-
(1999)
Oncogene
, vol.18
, pp. 5464-5472
-
-
Ameyar, M.1
Shatrov, V.2
Bouquet, C.3
-
35
-
-
1342325424
-
Bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation: Involvement of ERK1/ERK2 activity
-
Trisciuoglio D, Iervolino A, Candiloro A et al (2004) Bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation: involvement of ERK1/ERK2 activity. J Biol Chem 279:6737-6745
-
(2004)
J Biol Chem
, vol.279
, pp. 6737-6745
-
-
Trisciuoglio, D.1
Iervolino, A.2
Candiloro, A.3
-
36
-
-
0037500306
-
Persistent ERK phosphorylation negatively regulates cAMP response element-binding protein (CREB) activity via recruitment of CREB-binding protein to ppRSK
-
Wang Z, Zhang B, Wang M, Carr BI (2003) Persistent ERK phosphorylation negatively regulates cAMP response element-binding protein (CREB) activity via recruitment of CREB-binding protein to ppRSK. J Biol Chem 278:11138-11145
-
(2003)
J Biol Chem
, vol.278
, pp. 11138-11145
-
-
Wang, Z.1
Zhang, B.2
Wang, M.3
Carr, B.I.4
-
37
-
-
0034972061
-
p53 protein expression and oestrogen and progesterone receptor status in invasive ductal breast carcinomas
-
Ioakim-Liossi A, Karakitsos P, Markopoulos C et al (2001) p53 protein expression and oestrogen and progesterone receptor status in invasive ductal breast carcinomas. Cytopathology 2:197-202
-
(2001)
Cytopathology
, vol.2
, pp. 197-202
-
-
Ioakim-Liossi, A.1
Karakitsos, P.2
Markopoulos, C.3
-
38
-
-
0033527753
-
Mechanisms of transcriptional activation of Bcl-2 gene expression by 17beta-estradiol in breast cancer cells
-
Dong L, Wang W, Wang F et al (1999) Mechanisms of transcriptional activation of Bcl-2 gene expression by 17beta-estradiol in breast cancer cells. J Biol Chem 274:32099-32107
-
(1999)
J Biol Chem
, vol.274
, pp. 32099-32107
-
-
Dong, L.1
Wang, W.2
Wang, F.3
|