An analog of 1α,25-dihydroxy-19-norvitamin D3 with the 1α-hydroxy group fixed in the axial position lacks biological activity in vitro

Journal of Steroid Biochemistry and Molecular Biology

Volumn 103, Issue 3-5, 2007, Pages 293-297

  Sicinski, Rafal R ^a,b   Glebocka, Agnieszka ^a,b   Plum, Lori A ^a   DeLuca, Hector F ^a  

^a UNIVERSITY OF WARSAW   (Poland)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

19 Norvitamin D3; Cellular HL 60 differentiation; VDR binding; Vitamin D analogs; Vitamin D receptor

Indexed keywords

1ALPHA,25 DIHYDROXY 19 NORVITAMIN D3; 3BETA,25 DIHYDROXY 19 NORVITAMIN D3; OXYGEN DERIVATIVE; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE; 1,25 DIHYDROXY 19 NORVITAMIN D3; 1,25-DIHYDROXY-19-NORVITAMIN D3; CALCITRIOL; CALCITRIOL RECEPTOR; CALCIUM; DRUG DERIVATIVE;

ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CELL DIFFERENTIATION; CELL STRAIN HL 60; CONFORMATIONAL TRANSITION; DRUG SYNTHESIS; GEOMETRY; IN VITRO STUDY; IN VIVO STUDY; ISOMER; NONHUMAN; RECEPTOR BINDING; ANIMAL; BLOOD; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; FEMALE; HUMAN; HYDROXYLATION; METABOLISM; MOUSE; RAT; SYNTHESIS;

MUS;

ANIMALS; CALCITRIOL; CALCIUM; CELL DIFFERENTIATION; FEMALE; HL-60 CELLS; HUMANS; HYDROXYLATION; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RATS; RECEPTORS, CALCITRIOL;

EID: 33947167323     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2006.12.064     Document Type: Article

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