The chicken host peptides, gallinacins 4, 7, and 9 have antimicrobial activity against Salmonella serovars

Biochemical and Biophysical Research Communications

Volumn 356, Issue 1, 2007, Pages 169-174

  Milona, Panagiota ^a   Townes, Claire L ^a   Bevan, Richard M ^b   Hall, Judith ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Avian; Cationic antimicrobial peptide; Gallinacins; Salmonella

Indexed keywords

BETA DEFENSIN; GALLINACIN 4; GALLINACIN 7; GALLINACIN 9; HISTIDINE; MESSENGER RNA; PEPTIDE DERIVATIVE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BIRD; CHICKEN; CHROMOSOME 3; CONTROLLED STUDY; FEMALE; GENE CLUSTER; GENE INDUCTION; GENE LOCATION; GENETIC CONSERVATION; GENOME; HOST; HYDROPHOBICITY; IN VITRO STUDY; INNATE IMMUNITY; LIVER; LUNG; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALMONELLA; SALMONELLA ENTERICA; SALMONELLA ENTERITIDIS; SALMONELLA TYPHIMURIUM; SEROTYPE; SMALL INTESTINE; TRACHEA;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; AVIAN PROTEINS; BIRDS; CHICKENS; DEFENSINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION PROFILING; HEMOLYSIS; MICROBIAL VIABILITY; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; SALMONELLA; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS;

AVES; COLUMBA; GALLUS GALLUS; LARUS ARGENTATUS; PARUS CAERULEUS; SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLA ENTERITIDIS; SALMONELLA TYPHIMURIUM;

EID: 33947152401     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.02.098     Document Type: Article

References (26)

1. Ganz T. Microbiology: gut defence. Nature 422 (2003) 478-479
2. Salzman N.H., Ghosh D., Huttner K.M., Paterson Y., and Bevins C.L. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. Nature 422 (2003) 522-526
3. Selsted M.E., and Ouellette A.J. Mammalian defensins in the antimicrobial immune response. Nat. Immunol. 6 (2005) 551-557
4. Lehrer R.I., and Ganz T. Defensins of vertebrate animals. Curr. Opin. Immunol. 14 (2002) 96-102
5. Evans E.W., Beach F.G., Moore K.M., Jackwood M.W., Glisson J.R., and Harmon B.G. Antimicrobial activity of chicken and turkey heterophil peptides CHP1, CHP2, THP1, and THP3. Vet. Microbiol. 47 (1995) 295-303
6. Harwig S.S., Swiderek K.M., Kokryakov V.N., Tan L., Lee T.D., Panyutich E.A., Aleshina G.M., Shamova O.V., and Lehrer R.I. Gallinacins: cysteine-rich antimicrobial peptides of chicken leukocytes. FEBS Lett. 342 (1994) 281-285
7. Roosen S., Exner K., Paul S., Schroder J.M., Kalm E., and Looft C. Bovine beta-defensins: identification and characterization of novel bovine beta-defensin genes and their expression in mammary gland tissue. Mamm. Genome 15 (2004) 834-842
8. Brogden K.A. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?. Nat. Rev. Microbiol. 3 (2005) 238-250
9. Sugiarto H., and Yu P.L. Mechanisms of action of ostrich beta-defensins against Escherichia coli. FEMS Microbiol. Lett. (2007)
10. Brown K.L., and Hancock R.E. Cationic host defense (antimicrobial) peptides. Curr. Opin. Immunol. 18 (2006) 24-30
11. Zhao C., Nguyen T., Liu L., Sacco R.E., Brogden K.A., and Lehrer R.I. Gallinacin-3, an inducible epithelial beta-defensin in the chicken. Infect. Immun. 69 (2001) 2684-2691
12. van Dijk A., Veldhuizen E.J., Kalkhove S.I., Tjeerdsma-van Bokhoven J.L., Romijn R.A., and Haagsman H.P. The {beta}-defensin gallinacin-6 is expressed in the chicken digestive tract and has antimicrobial activity against food-borne pathogens. Antimicrob. Agents Chemother. (2006)
13. Lynn D.J., Higgs R., Gaines S., Tierney J., James T., Lloyd A.T., Fares M.A., Mulcahy G., and O'Farrelly C. Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken. Immunogenetics 56 (2004) 170-177
14. Xiao Y., Hughes A.L., Ando J., Matsuda Y., Cheng J.F., Skinner-Noble D., and Zhang G. A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins. BMC Genomics 5 (2004) 56
15. Hasenstein J.R., Zhang G., and Lamont S.J. Analyses of five gallinacin genes and the Salmonella enterica serovar Enteritidis response in poultry. Infect. Immun. 74 (2006) 3375-3380
16. Townes C.L., Michailidis G., Nile C.J., and Hall J. Induction of cationic chicken liver-expressed antimicrobial peptide 2 in response to Salmonella enterica infection. Infect. Immun. 72 (2004) 6987-6993
17. Wells M., Brown B., and Hall J. Pepsinogen C expression in intestinal IEC-6 cells. Cell Physiol. Biochem. 13 (2003) 301-308
18. Xiao Y., Cai Y., Bommineni Y.R., Fernando S.C., Prakash O., Gilliland S.E., and Zhang G. Identification and functional characterization of three chicken cathelicidins with potent antimicrobial activity. J. Biol. Chem. 281 (2006) 2858-2867
19. Yang D., Biragyn A., Kwak L.W., and Oppenheim J.J. Mammalian defensins in immunity: more than just microbicidal. Trends Immunol. 23 (2002) 291-296
20. Yang D., Chertov O., Bykovskaia S.N., Chen Q., Buffo M.J., Shogan J., Anderson M., Schroder J.M., Wang J.M., Howard O.M., and Oppenheim J.J. Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286 (1999) 525-528
21. Bar-Shira E., and Friedman A. Development and adaptations of innate immunity in the gastrointestinal tract of the newly hatched chick. Dev. Comp. Immunol. 30 (2006) 930-941
22. Sadeyen J.R., Trotereau J., Velge P., Marly J., Beaumont C., Barrow P.A., Bumstead N., and Lalmanach A.C. Salmonella carrier state in chicken: comparison of expression of immune response genes between susceptible and resistant animals. Microbes Infect. 6 (2004) 1278-1286
23. Yenugu S., Hamil K.G., Birse C.E., Ruben S.M., French F.S., and Hall S.H. Antibacterial properties of the sperm-binding proteins and peptides of human epididymis 2 (HE2) family; salt sensitivity, structural dependence and their interaction with outer and cytoplasmic membranes of Escherichia coli. Biochem. J. 372 (2003) 473-483
24. Behlau I., and Miller S.I. A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells. J. Bacteriol. 175 (1993) 4475-4484
25. Kluver E., Schulz-Maronde S., Scheid S., Meyer B., Forssmann W.G., and Adermann K. Structure-activity relation of human beta-defensin 3: influence of disulfide bonds and cysteine substitution on antimicrobial activity and cytotoxicity. Biochemistry 44 (2005) 9804-9816
26. Peschel A. How do bacteria resist human antimicrobial peptides?. Trends Microbiol. 10 (2002) 179-186