Novel action of n-3 polyunsaturated fatty acids: Inhibition of arachidonic acid-induced increase in tumor necrosis factor receptor expression on neutrophils and a role for proteases

Arthritis and Rheumatism

Volumn 56, Issue 3, 2007, Pages 799-808

  Moghaddami, Nahid ^a   Irvine, James ^a   Gao, Xiuhui ^b   Grover, Phulwinder K ^b   Costabile, Maurizio ^c   Hii, Charles S ^a   Ferrante, Antonio ^a,d  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^d WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DOCOSAHEXAENOIC ACID; FURA 2; ICOSAPENTAENOIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OMEGA 3 FATTY ACID; PROTEIN KINASE C; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFLAMMATION; LUMINESCENCE SPECTROMETRY; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RHEUMATOID ARTHRITIS; SPECTROMETRY; UPREGULATION; WESTERN BLOTTING;

ARACHIDONIC ACID; CALCIUM; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; EICOSAPENTAENOIC ACID; FATTY ACIDS, OMEGA-3; GENE EXPRESSION REGULATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUTROPHILS; PEPTIDE HYDROLASES; PROTEIN KINASE C; RECEPTORS, TUMOR NECROSIS FACTOR; UP-REGULATION;

EID: 33947125062     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.22432     Document Type: Article

References (45)

1. Ferrante A, Kowanko IC, Bates EJ. Mechanisms of host tissue damage by neutrophils activated by cytokines. In: Coffey RG, editor. Granulocyte responses to cytokines: basic and clinical research. New York: Marcel Dekker; 1992. p. 499-521.
2. Schimmer RC, Schrier DJ, Flory CM, Dykens J, Tung DK, Jacobson PB, et al. Streptococcal cell wall-induced arthritis: requirements for neutrophils, P-selectin, intercellular adhesion molecule-1, macrophage-inflammatory protein-2. J Immunol 1997;159:4103-8.
3. Wipke BT, Allen PM. Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J Immunol 2001;167:1601-8.
4. Emery P. Adalimumab therapy: clinical findings and implications for integration into clinical guidelines for rheumatoid arthritis. Drugs Today (Barc) 2005;41:155-63.
5. Kowanko IC, Ferrante A. Adhesion and TNF priming in neutrophil-mediated cartilage damage. Clin Immunol Immunopathol 1996;79:36-42.
6. Kowanko IC, Ferrante A, Clemente G, Youssef PP, Smith M. Tumor necrosis factor priming of peripheral blood neutrophils from rheumatoid arthritis patients. J Clin Immunol 1996;16:216-21.
7. Nozaki N, Yamaguchi S, Yamaoka M, Okuyama M, Nakamura H, Tomoike H. Enhanced expression and shedding of tumor necrosis factor receptors from mononuclear leukocytes in human heart failure. J Mol Cell Cardiol 1998;30:2003-12.
8. Tai DI, Tsai SL, Chen TC, Lo SK, Chang YH, Liaw YF. Modulation of tumor necrosis factor receptors 1 and 2 in chronic hepatitis B and C: the differences and implications in pathogenesis. J Biomed Sci 2001;8:321-7.
9. 2. J Immunol 2003;171:2616-24.
10. Calder PC. Dietary modification of inflammation with lipids. Proc Nutr Soc 2002;61:345-58.
11. Endres S, De Caterina R, Schmidt EB, Kristensen SD. n-3 polyunsaturated fatty acids: update 1995. Eur J Clin Invest 1995;25:629-38.
12. Meydani SN. Effect of n-3 polyunsaturated fatty acids on cytokine production and their biologic function. Nutrition 1996;12:S8-14.
13. Deckelbaum RJ, Akabas SR. n-3 Fatty acids and cardiovascular diseases: navigating towards recommendations [editorial]. Am J Clin Nutr 2006;84:1-2.
14. Ferrante A, Thong YH. A rapid one-step procedure for purification of mononuclear and polymorphonuclear leukocytes from human blood using a modification of the Hypaque-Ficoll technique. J Immunol Methods 1978;24:389-93.
15. Hii CS, Ferrante A, Edwards YS, Huang ZH, Hartfield PJ, Rathjen DA, et al. Activation of mitogen-activated protein kinase by arachidonic acid in rat liver epithelial WB cells by a protein kinase C-dependent mechanism. J Biol Chem 1995;270:4201-4.
16. Hii CS, Huang ZH, Bilney A, Costabile M, Murray AW, Rathjen DA, et al. Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa cells, HL60 promyelocytic leukemic cells, and human neutrophils: evidence for cell type-specific activation of mitogen-activated protein kinases. J Biol Chem 1998;273:19277-82.
17. Hardy SJ, Robinson BS, Ferrante A, Hii CS, Johnson DW, Poulos A, et al. Polyenoic very-long-chain fatty acids mobilize intracellular calcium from a thapsigargin-insensitive pool in human neutrophils: the relationship between Ca+ mobilization and superoxide production induced by long- and very-long-chain fatty acids. Biochem J 1995;311(Pt 2):689-97.
18. Badwey JA, Curnutte JT, Karnovsky ML. Cis-polyunsaturated fatty acids induce high levels of superoxide production in human neutrophils. J Biol Chem 1981;256:12640-3.
19. Steinbeck MJ, Robinson JM, Karnovsky MJ. Activation of the neutrophil NADPH-oxidase by free fatty acids requires the ionized carboxyl groups and partitioning into membrane lipids. J Leukoc Biol 1991;49:360-8.
20. Poulos A, Robinson BS, Ferrante A, Harvey DP, Hardy SJ, Murray AW. Effect of 22-32 carbon n-3 polyunsaturated fatty acids on superoxide production in human neutrophils: synergism of docosahexaenoic acid with f-met-leu-phe and phorbol ester. Immunology 1991;73:102-8.
21. Bates EJ, Ferrante A, Harvey D, Nandoskar M, Poulos A. Docosahexaenoic acid (22:6 n-3) but not eicosapentaenoic acid (20:5 n-3) can induce neutrophil-mediated injury of cultured endothelial cells: involvement of neutrophil elastase. J Leukoc Biol 1993;54:590-8.
22. Ferrante A, Hii CS, Costabile M. Regulation of neutrophil functions by fatty acids. In: Gabrilovich DI, editor. The neutrophils: new outlook for old cells. 2nd ed. London: Imperial College Press; 2005. p. 169-228.
23. Parker PJ, Murray-Rust J. PKC at a glance. J Cell Sci 2004;117(Pt 2):131-2.
24. Lew PD, Monod A, Waldvogel FA, Dewald B, Baggiolini M, Pozzan T. Quantitative analysis of the cystolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils. J Cell Biol 1986;102:2197-204.
25. Porteu F, Nathan CF. Mobilizable intracellular pool of p55 (type 1) tumor necrosis factor receptors in human neutrophils. J Leukoc Biol 1992;52:122-4.
26. Dri P, Gasparini C, Menegazzi R, Cramer R, Alberi L, Presani G, et al. TNF-induced shedding of TNF receptors in human polymorphonuclear leukocytes: role of the 55-kDa TNF receptor and involvement of a membrane-bound and non-matrix metalloproteinase. J Immunol 2000;165:2165-72.
27. Gasparini C, Menegazzi R, Patriarca P, Dri P. Evidence that elastase is the TNF-R75 shedding enzyme in resting human polymorphonuclear leukocytes. FEBS Lett 2003;553:360-4.
28. Bannenberg GL, Chiang N, Ariel A, Arita M, Tjonahen E, Gotlinger KH, et al. Molecular circuits of resolution: formation and actions of resolvins and protectins. J Immunol 2005;174:4345-55.
29. 2 activity in the human neutrophil. Biochem J 1993;291:825-31.
30. Robinson BS, Hii CS, Poulos A, Ferrante A. Effect of tumor necrosis factor-α on the metabolism of arachidonic acid in human neutrophils. J Lipid Res 1996;37:1234-45.
31. Nichols RC, Vanderhoek JY. 5-Hydroxyeicosanoids selectively stimulate the human neutrophil 15-lipoxygenase to use endogenous substrate. J Exp Med 1990;171:367-75.
32. Serhan CN, Hong S, Gronert K, Colgan SP, Devchand PR, Mirick G, et al. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 2002;196:1025-37.
33. Arita M, Bianchini F, Aliberti J, Sher A, Hong S, Yang R, et al. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J Exp Med 2005;201:713-22.
34. Corey SJ, Rosoff PM. Unsaturated fatty acids and lipoxygenase products regulate phagocyte NADPH oxidase activity by non-detergent mechanism. J Lab Clin Med 1991;118:343-51.
35. Hii CS, Moghadammi N, Dunbar A, Ferrante A. Activation of the phosphatidylinositol 3-kinase-Akt/protein kinase B signalling pathway in arachidonic acid-stimulated human myeloid and endothelial cells: involvement of the ErbB receptor family. J Biol Chem 2001;276:27246-55.
36. Dulin NO, Sorokin A, Douglas JG. Arachidonate-induced tyrosine phosphorylation of epidermal growth factor receptor and Shc-Grb2-Sos association. Hypertension 1998;32:1089-93.
37. McPhail LC, Clayton CC, Snyderman R. A potential second messenger role for unsaturated fatty acids: activation of Ca2+-dependent protein kinase. Science 1984;224:622-5.
38. Porteu F, Brockhaus M, Wallach D, Engelmann H, Nathan CF. Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor: comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils. J Biol Chem 1991;266:18846-53.
39. Ohmann HB, Campos M, McDougall L, Lawman MJ, Babiuk LA. Expression of tumor necrosis factor-α receptors on bovine macrophages, lymphocytes and polymorphonuclear leukocytes, internalization of receptor-bound ligand, and some functional effects. Lymphokine Res 1990;9:43-58.
40. Schleiffenbaum B, Fehr J. The tumor necrosis factor receptor and human neutrophil function: deactivation and cross-deactivation of tumor necrosis factor-induced neutrophil responses by receptor down-regulation. J Clin Invest 1990;86:184-95.
41. Porteu F, Nathan C. Shedding of tumor necrosis factor receptors by activated human neutrophils. J Exp Med 1990;172:599-607.
42. Bates EJ, Ferrante A, Harvey DP, Poulos A. Polyunsaturated fatty acids increase neutrophil adherence and integrin receptor expression. J Leukoc Biol 1993;53:420-6.
43. Simopoulos AP. Essential fatty acids in health and chronic disease. Am J Clin Nutr 1999;70:560-9.
44. Sperling RI. Dietary omega-3 fatty acids: effects on lipid mediators of inflammation and rheumatoid arthritis. Rheum Dis Clin North Am 1991;17:373-89.
45. Arend WP, Dayer JM. Cytokine and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum 1990;33:305-15.