The ups and downs of α-synuclein mRNA expression [12]

Movement Disorders

Volumn 22, Issue 2, 2007, Pages 293-295

  Dächsel, Justus C ^a   Lincoln, Sarah J ^a   Gonzalez, John ^a   Ross, Owen A ^a   Dickson, Dennis W ^a   Farrer, Matthew J ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; MESSENGER RNA;

BRAIN NERVE CELL; BRAIN REGION; DISEASE PREDISPOSITION; DOWN REGULATION; HUMAN; LETTER; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; UPREGULATION;

ALPHA-SYNUCLEIN; DEMENTIA; DISEASE PROGRESSION; DNA PROBES; HUMANS; MESENCEPHALON; PARKINSON DISEASE; PUTAMEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION; VISUAL CORTEX;

EID: 33847731132     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.21223     Document Type: Letter

References (9)

1. Singleton AB, Farrer M, Johnson J, et al. Alpha-synuclein locus triplication causes Parkinson's disease. Science 2003;302:841.
2. Chiba-Falek O, Lopez GJ, Nussbaum RL. Levels of alpha-synuclein mRNA in sporadic Parkinson disease patients. Mov Disord 2006;21:1703-1708.
3. Gutala RV, Reddy PH. The use of real-time PCR analysis in a gene expression study of Alzheimer's disease post-mortem brains. J Neurosci Methods 2004;132:101-107.
4. Vandesompele J, De Preter K, Pattyn F, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3:RESEARCH0034.
5. Kingsbury AE, Daniel SE, Sangha H, Eisen S, Lees AJ, Foster OJ. Alteration in alpha-synuclein mRNA expression in Parkinson's disease. Mov Disord 2004;19:162-170.
6. Beyer K, Lao JI, Carrato C, et al. Differential expression of alpha-synuclein isoforms in dementia with Lewy bodies. Neuropathol Appl Neurobiol 2004;30:601-607.
7. Neystat M, Lynch T, Przedborski S, Kholodilov N, Rzhetskaya M, Burke RE. Alpha-synuclein expression in substantia nigra and cortex in Parkinson's disease. Mov Disord 1999;14:417-422.
8. Rockenstein E, Hansen LA, Mallory M, Trojanowski JQ, Galasko D, Masliah E. Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease. Brain Res 2001;914:48-56.
9. Tan EK, Chandran VR, Fook-Chong S, et al. Alpha-synuclein mRNA expression in sporadic Parkinson's disease. Mov Disord 2005;20:620-623.