-
1
-
-
28844456475
-
The development of anti-amyloid therapy for Alzheimer's disease: From secretase modulators to polymerisation inhibitors
-
P.S. Aisen, The development of anti-amyloid therapy for Alzheimer's disease: from secretase modulators to polymerisation inhibitors, CNS Drugs 19 (2005), 989-996.
-
(2005)
CNS Drugs
, vol.19
, pp. 989-996
-
-
Aisen, P.S.1
-
2
-
-
27644493692
-
Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease
-
S. Barghorn, V. Nimmrich, A. Striebinger, C. Krantz, P. Keller, B. Janson, M. Bahr, M. Schmidt, R.S. Bitner, J. Harlan, E. Barlow, U. Ebert and H. Hillen, Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease, J Neurochem 31 (2005), 834-847.
-
(2005)
J Neurochem
, vol.31
, pp. 834-847
-
-
Barghorn, S.1
Nimmrich, V.2
Striebinger, A.3
Krantz, C.4
Keller, P.5
Janson, B.6
Bahr, M.7
Schmidt, M.8
Bitner, R.S.9
Harlan, J.10
Barlow, E.11
Ebert, U.12
Hillen, H.13
-
3
-
-
16944364644
-
Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma
-
A.L. Biere, B. Ostaszewski, E.R. Stimson, B.T. Hyman, J.E. Maggio and D.J. Selkoe, Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma, J Biol Chem 271 (1996), 32916-32922.
-
(1996)
J Biol Chem
, vol.271
, pp. 32916-32922
-
-
Biere, A.L.1
Ostaszewski, B.2
Stimson, E.R.3
Hyman, B.T.4
Maggio, J.E.5
Selkoe, D.J.6
-
4
-
-
16644379264
-
Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function
-
J.P. Cleary, D.M. Walsh, J.J. Hofmeister, G.M. Shankar, M.A. Kuskowski, D.J. Selkoe and K.H. Ashe, Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function, Nat Neurosci 1 (2005), 79-84.
-
(2005)
Nat Neurosci
, vol.1
, pp. 79-84
-
-
Cleary, J.P.1
Walsh, D.M.2
Hofmeister, J.J.3
Shankar, G.M.4
Kuskowski, M.A.5
Selkoe, D.J.6
Ashe, K.H.7
-
5
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability
-
K.N. Dahlgren, A.M. Manelli, W.B. Jr. Stine, L.K. Baker, G.A. Krafft and M.J. LaDu, Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability, J Biol Chem 277 (2002), 32046-32053.
-
(2002)
J Biol Chem
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr., W.B.3
Baker, L.K.4
Krafft, G.A.5
LaDu, M.J.6
-
6
-
-
0032893154
-
Appearance of sodium dodecyl sulfate-stable amyloid beta-protein (Abeta) dimer in the cortex during aging
-
M. Enya, M. Morishima-Kawashima, M. Yoshimura, Y. Shinkai, K. Kusui, K. Khan, D. Games, D. Schenk, S. Sugihara, H. Yamaguchi and Y. Ihara, Appearance of sodium dodecyl sulfate-stable amyloid beta-protein (Abeta) dimer in the cortex during aging, Am J Pathol 154 (1999), 271-279.
-
(1999)
Am J Pathol
, vol.154
, pp. 271-279
-
-
Enya, M.1
Morishima-Kawashima, M.2
Yoshimura, M.3
Shinkai, Y.4
Kusui, K.5
Khan, K.6
Games, D.7
Schenk, D.8
Sugihara, S.9
Yamaguchi, H.10
Ihara, Y.11
-
7
-
-
14844336875
-
Survival following dementia onset: Alzheimer's disease and vascular dementia
-
A.L. Fitzpatrick, L.H. Kuller, O.L. Lopez, C.H. Kawas and W. Jagust, Survival following dementia onset: Alzheimer's disease and vascular dementia, J Neurol Sci 229-230 (2005), 43-49.
-
(2005)
J Neurol Sci
, vol.229-230
, pp. 43-49
-
-
Fitzpatrick, A.L.1
Kuller, L.H.2
Lopez, O.L.3
Kawas, C.H.4
Jagust, W.5
-
8
-
-
14044279957
-
Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease
-
D.G. Georganopoulou, L. Chang, J.M. Nam, C.S. Thaxton, E.J. Mufson, W.L. Klein and C.A. Mirkin, Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease, Proc Natl Acad Sci USA 102 (2005), 2273-2276.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2273-2276
-
-
Georganopoulou, D.G.1
Chang, L.2
Nam, J.M.3
Thaxton, C.S.4
Mufson, E.J.5
Klein, W.L.6
Mirkin, C.A.7
-
9
-
-
0042838303
-
Alzheimer's disease-affected brain: Presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss
-
Y. Gong, L. Chang, K.L. Viola, P.N. Lacor, M.P. Lambert, C.E. Finch, G.A. Krafft and W.L. Klein, Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss, Proc Natl Acad Sci USA 100 (2003), 10417-10422.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10417-10422
-
-
Gong, Y.1
Chang, L.2
Viola, K.L.3
Lacor, P.N.4
Lambert, M.P.5
Finch, C.E.6
Krafft, G.A.7
Klein, W.L.8
-
11
-
-
21044453723
-
Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo
-
I. Klyubin, D.M. Walsh, C.A. Lemere, W.K. Cullen, G.M. Shankar, V. Betts, E.T. Spooner, L. Jiang, R. Anwyl, D.J. Selkoe and M.J. Rowan, Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo, Nat Med 6 (2005), 556-561.
-
(2005)
Nat Med
, vol.6
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
Spooner, E.T.7
Jiang, L.8
Anwyl, R.9
Selkoe, D.J.10
Rowan, M.J.11
-
12
-
-
0029671451
-
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains
-
Y.M. Kuo, M.R. Emmerling, C. Vigo-Pelfrey, T.C. Kasunic, J.B. Kirkpatrick, G.H. Murdoch, M.J. Ball and A.E. Roher, Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains, J Biol Chem 271 (1996), 4077-4081.
-
(1996)
J Biol Chem
, vol.271
, pp. 4077-4081
-
-
Kuo, Y.M.1
Emmerling, M.R.2
Vigo-Pelfrey, C.3
Kasunic, T.C.4
Kirkpatrick, J.B.5
Murdoch, G.H.6
Ball, M.J.7
Roher, A.E.8
-
13
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous systemneurotoxins
-
M.P. Lambert, A.K. Barlow, B.A. Chromy, C. Edwards, R. Freed, M. Liosatos, T.E. Morgan, I. Rozovsky, B. Trommer, K.L. Viola, P. Wals, C. Zhang, C.E. Finch, G.A. Krafft and W.L. Klein, Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous systemneurotoxins, Proc Natl Acad Sci USA 95 (1998), 6448-6453.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
14
-
-
0032888131
-
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
-
L.F Lue, Y.M. Kuo, A.E. Roher, L. Brachova, Y. Shen, L. Sue, T. Beach, J.H. Kurth, R.E. Rydel and J. Rogers, Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease, Am J Pathol 155 (1999), 853-862.
-
(1999)
Am J Pathol
, vol.155
, pp. 853-862
-
-
Lue, L.F.1
Kuo, Y.M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
Beach, T.7
Kurth, J.H.8
Rydel, R.E.9
Rogers, J.10
-
15
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
C.A. McLean, R.A. Cherny, F.W. Fraser, S.J. Fuller, M.J. Smith, K. Beyreuther, A.I. Bush and C.L. Masters, Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease, Ann Neurol 46 (1999), 860-866.
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
16
-
-
33644851439
-
The solvent protection of alzheimer amyloid-beta-(1-42) fibrils as determined by solution NMR spectroscopy
-
A. Olofsson, A.E. Sauer-Eriksson and A. Ohman, The solvent protection of alzheimer amyloid-beta-(1-42) fibrils as determined by solution NMR spectroscopy, J Biol Chem 281 (2006), 477-483.
-
(2006)
J Biol Chem
, vol.281
, pp. 477-483
-
-
Olofsson, A.1
Sauer-Eriksson, A.E.2
Ohman, A.3
-
17
-
-
0031871740
-
Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by Fluorescence correlation spectroscopy
-
M. Pitschke, R. Prior, M. Haupt and D. Riesner, Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by Fluorescence correlation spectroscopy, Nat Med 4 (1998), 832-834.
-
(1998)
Nat Med
, vol.4
, pp. 832-834
-
-
Pitschke, M.1
Prior, R.2
Haupt, M.3
Riesner, D.4
-
18
-
-
9444245809
-
Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease
-
A.E. Roher, M.O. Chaney, Y.M. Kuo, S.D. Webster, W.B. Stine, L.J. Haverkamp, A.S. Woods, R.J. Cotter, J.M. Tuohy, G.A. Krafft, B.S. Bonnell and M.R. Emmerling, Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease, J Biol Chem 271 (1996), 20631-20635.
-
(1996)
J Biol Chem
, vol.271
, pp. 20631-20635
-
-
Roher, A.E.1
Chaney, M.O.2
Kuo, Y.M.3
Webster, S.D.4
Stine, W.B.5
Haverkamp, L.J.6
Woods, A.S.7
Cotter, R.J.8
Tuohy, J.M.9
Krafft, G.A.10
Bonnell, B.S.11
Emmerling, M.R.12
-
19
-
-
11144310573
-
Effects of processing and storage conditions on amyloid beta (1-42) and tau concentrations in cerebrospinal fluid: Implications for use in clinical practice
-
N.S. Schoonenboom, C. Mulder, H. Vanderstichele, E.J. Van Elk, A. Kok, G.J. Van Kamp, P. Scheltens and M.A. Blankenstein, Effects of processing and storage conditions on amyloid beta (1-42) and tau concentrations in cerebrospinal fluid: implications for use in clinical practice, Clin Chem 51 (2005), 189-195.
-
(2005)
Clin Chem
, vol.51
, pp. 189-195
-
-
Schoonenboom, N.S.1
Mulder, C.2
Vanderstichele, H.3
Van Elk, E.J.4
Kok, A.5
Van Kamp, G.J.6
Scheltens, P.7
Blankenstein, M.A.8
-
20
-
-
21844448609
-
Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay
-
C. Stenh, H. Englund, A. Lord, A.S. Johansson, C.G. Almeida, P. Gellerfors, P. Greengard, G.K. Gouras, L. Lannfelt and L.N. Nilsson, Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay, Ann Neurol 58 (2005), 147-150.
-
(2005)
Ann Neurol
, vol.58
, pp. 147-150
-
-
Stenh, C.1
Englund, H.2
Lord, A.3
Johansson, A.S.4
Almeida, C.G.5
Gellerfors, P.6
Greengard, P.7
Gouras, G.K.8
Lannfelt, L.9
Nilsson, L.N.10
-
21
-
-
0027379395
-
Characterization of beta-amyloid peptide from human cerebrospinal fluid
-
C. Vigo-Pelfrey, D. Lee, P. Keim, I. Lieberburg and D.B. Schenk, Characterization of beta-amyloid peptide from human cerebrospinal fluid, J Neurochem 611 (1993), 1965-1968.
-
(1993)
J Neurochem
, vol.611
, pp. 1965-1968
-
-
Vigo-Pelfrey, C.1
Lee, D.2
Keim, P.3
Lieberburg, I.4
Schenk, D.B.5
-
22
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hip pocampal long-term potentiation in vivo
-
D.M. Walsh, I. Klyubin, J.V. Fadeeva, W.K. Cullen, R. Anwyl, M.S. Wolfe, M.J. Rowan and D.J. Selkoe, Naturally secreted oligomers of amyloid beta protein potently inhibit hip pocampal long-term potentiation in vivo, Nature 416 (2002), 535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
23
-
-
0034609516
-
The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain
-
D.M. Walsh, B.P. Tseng, R.E. Rydel, M.B. Podlisny and D.J. Selkoe, The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain, Biochemistry 39 (2000) 10831-10839.
-
(2000)
Biochemistry
, vol.39
, pp. 10831-10839
-
-
Walsh, D.M.1
Tseng, B.P.2
Rydel, R.E.3
Podlisny, M.B.4
Selkoe, D.J.5
-
24
-
-
0035900774
-
Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells
-
J. Wiltfang, H. Esselmann, P. Cupers, M. Neumann, H. Kretzschmar, M. Beyermann, D. Schleuder, H. Jahn, E. Ruther, J. Kornhuber, W. Annaert, B. De Strooper and P. Saftig, Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells, J Biol Chem 276 (2001), 42645-42657.
-
(2001)
J Biol Chem
, vol.276
, pp. 42645-42657
-
-
Wiltfang, J.1
Esselmann, H.2
Cupers, P.3
Neumann, M.4
Kretzschmar, H.5
Beyermann, M.6
Schleuder, D.7
Jahn, H.8
Ruther, E.9
Kornhuber, J.10
Annaert, W.11
De Strooper, B.12
Saftig, P.13
|