Multispectral quantification of tissue types in a RIF-1 tumor model with histological validation. Part I

Magnetic Resonance in Medicine

Volumn 57, Issue 3, 2007, Pages 501-512

  Henning, Erica C ^a   Azuma, Chieko ^b   Sotak, Christopher H ^a,c,d   Helmer, Karl G ^a,e  

^a Worcester Polytechnic Institute   (United States)

^b TUFTS UNIVERSITY   (United States)

^c Worcester Polytechnic Institute   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Diffusion; HIF 1; Multispectral analysis; RIF 1; Tumor

Indexed keywords

CELL DEATH; DIFFUSION; PATIENT TREATMENT; SURFACE DIFFUSION; TUMORS;

APPARENT DIFFUSION COEFFICIENT; HIF-1; HYPOXIA INDUCIBLE FACTOR-1 ALPHA; MULTI-SPECTRAL ANALYSIS; MULTIPLE COMPARTMENTS; RADIATION INDUCED FIBROSARCOMA; RIF-1; THERAPEUTIC EFFICACY;

K-MEANS CLUSTERING;

HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DISEASE SEVERITY; FEMALE; FIBROSARCOMA; HISTOLOGY; HYPOXIA; IMAGE PROCESSING; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; QUANTITATIVE DIAGNOSIS; TISSUE CHARACTERIZATION; TISSUE NECROSIS; TREATMENT PLANNING;

EID: 33847693987     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.21161     Document Type: Article

References (46)

1. Raghunand N, Gatenby RA, Gillies RJ. Microenvironmental and cellular consequences of altered blood now in tumours. Br J Radiol 2003;76:Sll-S22.
2. 2 homeostasis. Curr Opin Genet Dev 1998;8:588-594.
3. Gray LH, Conger AD, Ebert M, Hornsey S, Scott OC. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 1953;26:638-648.
4. Prasad KN. Cellular radiation damage. Handbook of radiobiology. Boca Raton: CRC Press; 1995. p 49-59.
5. Rofstad EK, Sundfor K, Lyng H, Trope CG. Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis. Br J Cancer 2000;83:354-359.
6. Burri P, Djonov V. Aebersold DM, Lindel K, Studer U, Altermatt HJ, Mazzacchelli L, Greinur RH, Gruber G. Significant correlation of hypoxia-inducible factor-1α with treatment outcome in cervical cancer treated with radical radiotherapy. Int J Radiat Oncol Biol Phys 2003;56:494-501.
7. Nordsmark M. Overgaard M, Overgaard J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 1996;41:31-39.
8. Koukourakis MI, Giatromanolaki A, Skarlatos J, Corti L, Blandamura S, Piazza M, Gatter KC, Harris AL. Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. Cancer Res 2001;61:1830-1832.
9. Cerniglia GJ, Wilson DF, Pawlowski M, Vinogradov S, Biaglow J. Intravascular oxygen distribution in subcutaneous 9L tumors and radiation sensitivity. J Appl Physiol 1997;82:1939-1945.
10. Zips D, Eicheler W, Bruchner K, Jackisch T, Geyer P, Petersen C, van der Kogel AJ, Baumann M. Impact of the tumour bed effect on microenvironment, radiobiological hypoxia and the outcome of fractionated radiotherapy of human FaDu squamous-cell carcinoma growing in nude mice. Int J Radiat Biol 2001;77:1185-1193.
11. Chia SK, Wykoff CC, Watson PH, Han C, Leek RD, Pastorek J, Gatter KC, Ratcliffe P, Harris AL. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. J Clin Oncol 2001;19:3660-3668.
12. Vleugel MM, Greijer AE, Shvarts A, van der Groep P, van Berkel M, Aarbodem Y, van Tinteren H, Harris AL, van Diest PJ, van der Wall E. Differential prognostic impact of hypoxia induced and diffuse HIF-1α expression in invasive breast cancer. J Clin Pathol 2005;58:172-177.
13. Giatromanolaki A, Koukourakis MI, Sivridis E, Pastorek J, Wykoff CC, Gatter KC, Harris AL. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res 2001;61:7992-7998.
14. Olive PL, Banath JP, Aquino-Parsons C. Measuring hypoxia in solid tumours-is there a gold standard? Acta Oncol 2001;40:917-923.
15. Nordsmark M, Loncaster J, Aquino-Parsons C, Chou SC, Ladekarl M, Havsteen H. Lindegaard JC, Davidson SE, Varia M, West C, Hunter R, Overgaard J, Raleigh JA. Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas. Radiother Oncol 2003;67:35-44.
16. Evans SM, Judy KD, Dunphy I, Jenkins WT, Nelson PT, Collins R, Wileyto EP, Jenkins K, Hahn SM, Stevens CW, Judkins AR, Phillips P, Geoerger B, Koch CJ. Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding. Cancer Res 2004;64:1886-1892.
17. Helmer KG, Han S, Sotak CH. On the correlation between the water diffusion coefficient and oxygen tension in RIF-1 tumors. NMR Biomed 1998;11:120-130.
18. Lyng H, Haraldseth O, Rofstad EK. Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging. Magn Reson Med 2000;43:828-836.
19. Helmer KG, Meiler MR, Sotak CH, Petruccelli JD. Comparison of the return-to-the-origin probability and the apparent diffusion coefficient of water as indicators of necrosis in RIF-1 tumors. Magn Reson Med 2003;49:468-478.
20. Herneth AM, Guccione S, Bednarski M. Apparent diffusion coefficient: a quantitative parameter for in vivo tumor characterization. Eur J Radiol 2003;45:208-213.
21. Muti M, Aprile I, Principi M, Italiani M, Guiducci A, Giulianelli G, Ottaviano P. Study on the variations of the apparent diffusion coefficient in areas of solid tumor in high grade gliomas. Magn Reson Imaging 2002;20:635-641.
22. Sinha S, Sinha U. Functional magnetic resonance of human breast tumors. Ann NY Acad Sci 2002;980:95-115.
23. 1H-NMR spectroscopy in a murino tumor in vivo. Br J Cancer 1996;73:61-64.
24. Galons JP, Altbach MI, Paine-Murrieta GD, Taylor CW, Gillies RJ. Early increases in breast tumor xenograft water mobility in response to paclitaxel therapy detected by non-invasive diffusion magnetic resonance imaging. Neoplasia 1999;1:113-117.
25. Chenevert TL, McKeever PE, Ross BD. Monitoring early response of experimental brain tumors to therapy using diffusion magnetic resonance imaging. Clin Cancer Res 1997;3:1457-1466.
26. Chenevert TL, Stegman LD, Taylor JMG, Robertson PL, Greenberg HS, Rehemtulla A, Ross BD. Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst 2000;92:2029-2036.
27. Dzik-Jurasz A, Domenig C, George M, Wolbor J, Padhani A, Brown G, Doran S. Diffusion MRI for prediction of response of rectal cancer to chemoradiation. Lancet 2002;360:307-308.
28. Tzika AA, Astrakas LG, Zarifi MK, Petridou N, Young-Poussaint T, Goumnerova L, Zurakowski D, Anthony DC, Black PM. Multiparametric MR assessment of pediatric brain tumors. Neuroradiology 2003;45:1-10.
29. Clark MC, Hall LO, Goldgof DB, Velthuizen R, Murtagh FR, Silbiger MS. Automatic tumor segmentation using knowledge-based techniques. IEEE Trans Med Imaging 1998;17:187-201.
30. Jacobs MA, Barker PB, Bluemke DA, Maranto C, Arnold C. Herskovits EH, Bhujwalla Z. Benign and malignant breast lesions: diagnosis with multiparametric MR imaging. Radiology 2003;229:225-232.
31. Carano RA, Ross AL, Ross J, Williams SP, Koeppen H, Schwall RH, van Bruggen N. Quantification of tumor tissue populations by multispectral analysis. Magn Reson Med 2004;51:542-551.
32. Duda R, Hart P. Pattern classification. New York: John Wiley & Sons; 2001.
33. Carano RA, Takano K, Helmer KG, Tatlisumak T, Irie K, Petrucelli JD, Fisher M, Sotak CH. Determination of focal ischemic lesion volume in the rat brain using multispectral analysis. J Magn Reson Med 1998;8:1266-1278.
34. Carano RA, Li F, Irie K, Helmer KG, Silva MD, Fisher M, Sotak CH. Multispectral analysis of the temporal evolution of cerebral ischemia in the rat brain. J Magn Reson Imaging 2000;12:842-858.
35. Brinkmann BH, Manduca A, Robb RA. Optimized homomorphic unsharp masking for MR grayscale inhomogeneity correction. IEEE Trans Med Imaging 1998;17:161-171.
36. Loukas CG, Linney A. A survey on histological image analysis-based assessment of three major biological factors influencing radiotherapy: proliferation, hypoxia, and vasculature. Comput Methods Programs Biomed 2004;74:183-199.
37. Russ JC. Fractal analysis. The image processing handbook. 2nd ed. Boca Raton: CRC Press; 1995. p 262-270.
38. Kazemi M, Silva MD, Li F, Fisher M, Cohen Y, Sotak CH. Investigation of techniques to quantify in vivo lesion volume based on comparison of water apparent diffusion coefficient (ADC) maps with histology in focal cerebral ischemia of rats. Magn Reson Imaging 2004;22:653-659.
39. Hashizume H, Baluk P, Morikawa S, McLean JW, Thurston G, Roberge S, Jain RK, McDonald DM. Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol 2000;156:1363-1380.
40. Gomori JM, Grossman RI, Yu-Ip C, Asakura T. NMR relaxation times of blood: dependence on field strength, oxidation state, and cell integrity. J Comput Assist Tomogr 1987;11:684-690.
41. Ryschich E, Schmidt J, Hammerling GJ, Klar E, Ganss R. Transformation of the microvascular system during multistage tumorigenesis. Int J Cancer 2002;97:719-725.
42. Ryschich E, Schmidt E, Maksan SM, Klar E, Schmidt J. Expansion of the endothelial surface by an increase of vessel diameter during tumor angiogenesis in experimental hepatocellular and pancreatic cancer. World J Gastroenterol 2004;10:3171-3174.
43. Gillies RJ, Raghunand N, Karczmar GS, Bhujwalla ZM. MRI of the tumor microenvironment. J Magn Reson Imaging 2002;16:430-450.
44. Zhong H, De Marzo AM, Laughner E, Lini M, Hilton DA, Zagzag D, Buechler P, Isaacs WB, Semenza GL, Simons JW. Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases. Cancer Res 1999;59:5830-5835.
45. Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 2000:157:411-421.
46. Chinnaiyan AM, Prasad U, Shankar S, Hamstra DA, Shanaiah M, Chenevert TL, Ross BD, Rehemtulla A. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci USA 2000;97:1754-1759.