Identification of the human liver UDP-glucuronosyltransferase involved in the metabolism of p-ethoxyphenylurea (dulcin)

Archives of Toxicology

Volumn 81, Issue 3, 2007, Pages 163-168

  Uesawa, Yoshihiro ^a   Staines, Adam G ^b   Lockley, David ^b   Mohri, Kiminori ^a   Burchell, Brian ^b  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Dulcin; Glucuronidation; UGT1A1; UGT1A9; Ureido group

Indexed keywords

4 ETHOXYPHENYLUREA; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A9; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GLUCURONIDATION; HUMAN; HUMAN CELL; LIVER; LIVER METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BILIRUBIN; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; ISOENZYMES; LIVER; PHENOLPHTHALEIN; PHENYLUREA COMPOUNDS;

ORYCTOLAGUS CUNICULUS;

EID: 33847675323     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-006-0138-5     Document Type: Article

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