c-Src protein kinase inhibitors block assembly and maturation of dengue virus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 9, 2007, Pages 3520-3525

  Chu, J J H ^a   Yang, Priscilla L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Antiviral; Chemical biology; Flavivirus; High throughput screen; Small molecule inhibitor

Indexed keywords

4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; ANTIVIRUS AGENT; AZD 0530; DASATINIB; DIMETHYL SULFOXIDE; IMATINIB; KENPAULLONE; LAVENDUSTIN A; LAVENDUSTIN C; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SU 11652; TYRPHOSTIN 46; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DENGUE VIRUS; DRUG MECHANISM; DRUG POTENCY; DRUG SAFETY; DRUG TARGETING; FLAVIVIRUS; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPRODUCIBILITY; RNA INTERFERENCE; ROBOTICS; SEROTYPE; VIRION; VIROGENESIS; VIRUS ASSEMBLY; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION;

ANIMALS; CERCOPITHECUS AETHIOPS; CYTOTOXICITY TESTS, IMMUNOLOGIC; DENGUE VIRUS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; PYRIMIDINES; RNA INTERFERENCE; THIAZOLES; VERO CELLS; VIRUS ASSEMBLY;

DENGUE VIRUS; FLAVIVIRUS; MURINAE;

EID: 33847671789     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0611681104     Document Type: Article

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