Haloperidol challenge in healthy male humans: A functional magnetic resonance imaging study

Neuroscience Letters

Volumn 340, Issue 3, 2003, Pages 193-196

  Brassen, Stefanie ^a,b   Tost, Heike ^a   Hoehn, Fabian ^a   Weber Fahr, Wolfgang ^a   Klein, Sabine ^a   Braus, Dieter F ^a,b  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Antipsychotics; Dopamine; Functional magnetic resonance imaging; Haloperidol; Healthy subjects

Indexed keywords

HALOPERIDOL; NEUROLEPTIC AGENT;

ADULT; ARTICLE; AUDITORY STIMULATION; BRAIN REGION; CONTROLLED STUDY; DRUG EFFECT; HUMAN; LINGUAL GYRUS; MALE; MIDDLE OCCIPITAL GYRUS; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN BLOOD LEVEL; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; VISUAL STIMULATION;

EID: 0037451861     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00104-6     Document Type: Article

References (17)

1. Bartlett E.J., Brodie J.D., Simkowitz P., Dewey S.L., Rusinek H., Wolf A.P., Fowler J.S., Volkow N.D., Smith G., Wolkin A. Effects of haloperidol challenge on regional cerebral glucose utilization in normal human subjects. Am. J. Psychiatry. 151:1994;681-686.
2. Braus D.F., Brassen S., Demirakca T., Weimer E., Ruf M. Psychopharmakaeffekte und moderne Kernspintomographie: Stand der Diskussion, Möglichkeiten und Grenzen. Nervenheilkunde. 21:2002;363-371.
3. Braus D.F., Ende G., Weber-Fahr W., Sartorius A., Krier A., Hubrich-Ungureanu P., Ruf M., Stuck S., Henn F.A. Antipsychotic drug effects on motor activation measured by functional magnetic resonance imaging in schizophrenic patients. Schizophr. Res. 39:1999;19-29.
4. Braus D.F., Weber-Fahr W., Tost H., Ruf M., Henn F.A. Sensory information processing in neuroleptic-naive first-episode schizophrenic patients: a functional magnetic resonance imaging study. Arch. Gen. Psychiatry. 59:2002;696-701.
5. Cavallotti C., Nuti F., Bruzzone P., Mancone M. Age-related changes in dopamine D2 receptors in rat heart and coronary vessels. Clin. Exp. Pharmacol. Physiol. 29:2002;412-418.
6. Edvinsson L., Hardebo J.E., Harper A.M., McCulloch J., Owman C. Action of dopamine agonists on brain vessels in vitro and after in vivo microapplication. Acta Neurol. Scand. Suppl. 64:1977;350-351.
7. Friston K.J., Holmes A.P., Price C.J., Buchel C., Worsley K.J. Multisubject fMRI studies and conjunction analyses. Neuroimage. 10:1999;385-396.
8. Friston K.J., Holmes A.P., Worsley K.P., Poline J.-B., Frith C.D., Frackowiak R.S. Statistical parametric maps in functional imaging: a general linear approach. Hum. Brain Mapp. 2:1995;189-210.
9. He G.Q., Zhang A., Altura B.T., Altura B.M. Cocaine-induced cerebrovasospasm and its possible mechanism of action. J. Pharmacol. Exp. Ther. 268:1994;1532-1539.
10. Holcomb H.H., Cascella N.G., Thaker G.K., Medoff D.R., Dannals R.F., Tamminga C.A. Functional sites of neuroleptic drug action in the human brain: PET/FDG studies with and without haloperidol. Am. J. Psychiatry. 153:1996;41-49.
11. Jibiki I., Takizawa Y., Yamaguchi N. Visual dysfunction in treated schizophrenia suggested by visual evoked potentials from pattern-reversal stimulation. Eur. Arch. Psychiatry Clin. Neurosci. 241:1991;61-64.
12. Kahn D.A., Prohovnik I., Lucas L.R., Sackeim H.A. Dissociated effects of amphetamine on arousal and cortical blood flow in humans. Biol. Psychiatry. 25:1989;755-767.
13. Miller D.D., Rezai K., Alliger R., Andreasen N.C. The effect of antipsychotic medication on relative cerebral blood perfusion in schizophrenia: assessment with technetium-99m hexamethyl- propyleneamine oxime single photon emission computed tomography. Biol. Psychiatry. 41:1997;550-559.
14. Song A.W., Fichtenholtz H., Woldorff M. BOLD signal compartmentalization based on the apparent diffusion coefficient. Magn. Reson. Imaging. 20:2002;521-525.
15. Steinhausen M., Weis S., Fleming J., Dussel R., Parekh N. Responses of in vivo renal microvessels to dopamine. Kidney Int. 30:1986;361-370.
16. Tamminga C., Holcomb H. Neural networks: neural systems vi: basal ganglia. Am. J. Psychiatry. 158:2001;185.
17. Tamminga C.A., Holcomb H.H. Neural networks: neural systems VI: basal ganglia. Am. J. Psychiatry. 158:2001;185.