-
1
-
-
0028351657
-
Chemotherapy for colorectal cancer
-
Moertel C.G. Chemotherapy for colorectal cancer. N Engl J Med 330 (1994) 1136-1142
-
(1994)
N Engl J Med
, vol.330
, pp. 1136-1142
-
-
Moertel, C.G.1
-
2
-
-
0026721532
-
Advanced Colorectal Cancer Meta-Analysis Project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
-
Advanced Colorectal Cancer Meta-Analysis Project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate. J Clin Oncol 10 (1992) 896-903
-
(1992)
J Clin Oncol
, vol.10
, pp. 896-903
-
-
-
3
-
-
0022656553
-
Sensitivity of human, murine, and rat cells to 5-fluorouraicl and 5′-deoxy-5-fluorouracil in relation to drug-metabolizing enzymes
-
Peters G.J., Laurensse E., Leyva A., et al. Sensitivity of human, murine, and rat cells to 5-fluorouraicl and 5′-deoxy-5-fluorouracil in relation to drug-metabolizing enzymes. Cancer Res 46 (1986) 20-28
-
(1986)
Cancer Res
, vol.46
, pp. 20-28
-
-
Peters, G.J.1
Laurensse, E.2
Leyva, A.3
-
4
-
-
0026045814
-
A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa
-
Peters G.J., Groeningen C.J., Laurensse E.J., and Pinedo H.M. A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa. Cancer 68 (1991) 1903-1909
-
(1991)
Cancer
, vol.68
, pp. 1903-1909
-
-
Peters, G.J.1
Groeningen, C.J.2
Laurensse, E.J.3
Pinedo, H.M.4
-
5
-
-
85008280346
-
Metabolism of fluoropyrimidine in cancer patients (Part II)
-
Yasue K., Usami Y., Hashizume H., et al. Metabolism of fluoropyrimidine in cancer patients (Part II). Jpn J Clin Pharmacol Ther 18 (1987) 689-698
-
(1987)
Jpn J Clin Pharmacol Ther
, vol.18
, pp. 689-698
-
-
Yasue, K.1
Usami, Y.2
Hashizume, H.3
-
6
-
-
0023187085
-
Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile
-
Heggie G.D., Sommadossi J.P., Cross D.S., Husster W.J., and Diasio R.B. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile. Cancer Res 47 (1987) 2203-2206
-
(1987)
Cancer Res
, vol.47
, pp. 2203-2206
-
-
Heggie, G.D.1
Sommadossi, J.P.2
Cross, D.S.3
Husster, W.J.4
Diasio, R.B.5
-
7
-
-
0036257036
-
Prognostic value of thymidine phosphorylase/PD-ECGF in advanced colorectal cancer after surgery: evaluation with a new monoclonal antibody
-
Tokunaga Y., Hosogi H., Hoppou T., Nakagami M., Tokuka A., and Ohsumi K. Prognostic value of thymidine phosphorylase/PD-ECGF in advanced colorectal cancer after surgery: evaluation with a new monoclonal antibody. Surgery 131 (2002) 541-547
-
(2002)
Surgery
, vol.131
, pp. 541-547
-
-
Tokunaga, Y.1
Hosogi, H.2
Hoppou, T.3
Nakagami, M.4
Tokuka, A.5
Ohsumi, K.6
-
8
-
-
0038001472
-
The usefulness of immunohistochemical evaluation of dihydropyrimidine dehydrogenase for rectal cancer treated with preoperative radiotherapy
-
Komuro Y., Watanabe T., Tsuno N., et al. The usefulness of immunohistochemical evaluation of dihydropyrimidine dehydrogenase for rectal cancer treated with preoperative radiotherapy. Hepatogastroenterology 50 (2003) 906-911
-
(2003)
Hepatogastroenterology
, vol.50
, pp. 906-911
-
-
Komuro, Y.1
Watanabe, T.2
Tsuno, N.3
-
9
-
-
28544436512
-
Clinical role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in colorectal cancer treated with postoperative fluoropyrimidine
-
Tokunaga Y., Takahashi K., and Saito T. Clinical role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in colorectal cancer treated with postoperative fluoropyrimidine. Hepatogastroenterology 52 (2005) 1715-1721
-
(2005)
Hepatogastroenterology
, vol.52
, pp. 1715-1721
-
-
Tokunaga, Y.1
Takahashi, K.2
Saito, T.3
-
10
-
-
0029922396
-
Reduced activity of anabolizing enzymes in 5-fluorouracil resistant human stomach cancer cells
-
Inaba M., Mitsuhashi J., Sawada H., et al. Reduced activity of anabolizing enzymes in 5-fluorouracil resistant human stomach cancer cells. Jpn J Cancer Res 87 (1996) 212-220
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 212-220
-
-
Inaba, M.1
Mitsuhashi, J.2
Sawada, H.3
-
11
-
-
0029977357
-
Estimation of pathway of 5-fluorouracil anabolism in human cancer cells in vitro and in vivo
-
Fukushima M., Nomura H., Murakami Y., et al. Estimation of pathway of 5-fluorouracil anabolism in human cancer cells in vitro and in vivo. Jpn J Cancer Chemother 23 (1996) 721-731
-
(1996)
Jpn J Cancer Chemother
, vol.23
, pp. 721-731
-
-
Fukushima, M.1
Nomura, H.2
Murakami, Y.3
-
12
-
-
0033696046
-
Adenoviral-mediated transfer of Escherichia coli uracil phosphoribosyltransferase (UPRT) gene to modulate the sensitivity of the human colon cancer cells to 5-fluorouracil
-
Koyama F., Sawada H., Fujii H., et al. Adenoviral-mediated transfer of Escherichia coli uracil phosphoribosyltransferase (UPRT) gene to modulate the sensitivity of the human colon cancer cells to 5-fluorouracil. Eur J Cancer 36 (2000) 2403-2410
-
(2000)
Eur J Cancer
, vol.36
, pp. 2403-2410
-
-
Koyama, F.1
Sawada, H.2
Fujii, H.3
-
13
-
-
19544377867
-
Preparation of anti-OPRT antibody for immunochemical detection
-
Sakamoto K., Sugimoto Y., Miyadera K., Oka T., and Fukushima M. Preparation of anti-OPRT antibody for immunochemical detection. Gan To Kagaku Ryoho 32 (2005) 653-658
-
(2005)
Gan To Kagaku Ryoho
, vol.32
, pp. 653-658
-
-
Sakamoto, K.1
Sugimoto, Y.2
Miyadera, K.3
Oka, T.4
Fukushima, M.5
-
14
-
-
17644377191
-
Heat-assisted stretching of paraffin section on hot plate weakens immunoreactivity of orotate phosphoribosyltransferase
-
Kamoshida S., Sakamoto N., Matsuoka H., et al. Heat-assisted stretching of paraffin section on hot plate weakens immunoreactivity of orotate phosphoribosyltransferase. Acta Histochem Cytochem 38 (2005) 69-74
-
(2005)
Acta Histochem Cytochem
, vol.38
, pp. 69-74
-
-
Kamoshida, S.1
Sakamoto, N.2
Matsuoka, H.3
-
15
-
-
0034204192
-
Expression of recombinant human dihydropyrimidine dehydrogenase and its application to the preparation of anti-DPD antibodies for immunochemical detection
-
Okabe H., Arakawa K., Takechi T., and Fukushima M. Expression of recombinant human dihydropyrimidine dehydrogenase and its application to the preparation of anti-DPD antibodies for immunochemical detection. Jpn J Cancer Chemother 27 (2000) 891-899
-
(2000)
Jpn J Cancer Chemother
, vol.27
, pp. 891-899
-
-
Okabe, H.1
Arakawa, K.2
Takechi, T.3
Fukushima, M.4
-
16
-
-
0037862137
-
Prognostic effects of dihydropyrimidine dehydrogenase in advanced colorectal cancer after surgery: immunohistochemistry using a new monoclonal antibody
-
Tokunaga Y., Nakagami M., Tokuka A., and Ohsumi K. Prognostic effects of dihydropyrimidine dehydrogenase in advanced colorectal cancer after surgery: immunohistochemistry using a new monoclonal antibody. Anticancer Res 23 (2003) 1763-1768
-
(2003)
Anticancer Res
, vol.23
, pp. 1763-1768
-
-
Tokunaga, Y.1
Nakagami, M.2
Tokuka, A.3
Ohsumi, K.4
-
18
-
-
0343396762
-
A new rapid immunohistochemical staining technique using the Envision antibody Complex
-
Kammerer U., Kapp M., Gussel A.M., et al. A new rapid immunohistochemical staining technique using the Envision antibody Complex. J Histochem Cytochem 49 (2001) 623-630
-
(2001)
J Histochem Cytochem
, vol.49
, pp. 623-630
-
-
Kammerer, U.1
Kapp, M.2
Gussel, A.M.3
-
19
-
-
0031595677
-
The EnVision+ system: anew immunohistochemical method for diagnosis and research. Critical comparison with the APPAP, Chem Mate, CSA, LABC, and SABC technique
-
Sabattini E., Bisgaard K., Ascani S., et al. The EnVision+ system: anew immunohistochemical method for diagnosis and research. Critical comparison with the APPAP, Chem Mate, CSA, LABC, and SABC technique. J Clin Pathol 51 (1998) 506-511
-
(1998)
J Clin Pathol
, vol.51
, pp. 506-511
-
-
Sabattini, E.1
Bisgaard, K.2
Ascani, S.3
-
20
-
-
0024852342
-
Catalyzed reporter deposition, a novel method of signal amplification: application to immunoassays
-
Bobrow M., Harris T.D., Shaughnessy K.J., and Litt G.J. Catalyzed reporter deposition, a novel method of signal amplification: application to immunoassays. J Immunol Meth 125 (1989) 279-284
-
(1989)
J Immunol Meth
, vol.125
, pp. 279-284
-
-
Bobrow, M.1
Harris, T.D.2
Shaughnessy, K.J.3
Litt, G.J.4
-
22
-
-
0023464656
-
Statistical methods in cancer research. Volume II: the design and analysis of cohort studies
-
Breslow N.E., and Day N.E. Statistical methods in cancer research. Volume II: the design and analysis of cohort studies. IARC Sci Publ (1987) 1-406
-
(1987)
IARC Sci Publ
, pp. 1-406
-
-
Breslow, N.E.1
Day, N.E.2
-
23
-
-
0037325801
-
Correlation between clinicopathologic factors and kinetics of metabolic enzymes for 5-fluorouracil given to patients colon carcinoma by two different dosage regimens
-
Katsumata K., Tomioka H., Sumi T., et al. Correlation between clinicopathologic factors and kinetics of metabolic enzymes for 5-fluorouracil given to patients colon carcinoma by two different dosage regimens. Cancer Chemother Pharmacol 51 (2003) 155-160
-
(2003)
Cancer Chemother Pharmacol
, vol.51
, pp. 155-160
-
-
Katsumata, K.1
Tomioka, H.2
Sumi, T.3
-
24
-
-
0029977357
-
Analysis of phosphorylation pathway of 5-fluorouracil in human cancer cell
-
Fukushima M., Nomura Y., Murakami Y., Shirasaka T., and Aiba K. Analysis of phosphorylation pathway of 5-fluorouracil in human cancer cell. Gan to Kagaku Ryoho 6 (1996) 721-731
-
(1996)
Gan to Kagaku Ryoho
, vol.6
, pp. 721-731
-
-
Fukushima, M.1
Nomura, Y.2
Murakami, Y.3
Shirasaka, T.4
Aiba, K.5
-
25
-
-
0035875466
-
Fluoropyrimidine sensitivity of human MCF-7 breast cancer cells stably transfected with human uridine phosphorylase
-
Cuq P., Rouquet C., Evrard A., Ciccolini J., Vian L., and Cano J.P. Fluoropyrimidine sensitivity of human MCF-7 breast cancer cells stably transfected with human uridine phosphorylase. Br J Cancer 84 (2001) 1677-1680
-
(2001)
Br J Cancer
, vol.84
, pp. 1677-1680
-
-
Cuq, P.1
Rouquet, C.2
Evrard, A.3
Ciccolini, J.4
Vian, L.5
Cano, J.P.6
-
26
-
-
0022214278
-
Role of uridine phosphorylase in the anabosim of 5-fluorouracil
-
Schwartz P.M., Moir R.D., Hyde C.M., Turek P.J., and Handeschumacher R.E. Role of uridine phosphorylase in the anabosim of 5-fluorouracil. Biochem Pharmacol 34 (1985) 3585-3589
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 3585-3589
-
-
Schwartz, P.M.1
Moir, R.D.2
Hyde, C.M.3
Turek, P.J.4
Handeschumacher, R.E.5
-
27
-
-
0024807857
-
Species differences in substrate specificity of pyrimidine nucleoside phosphorylase
-
Maehara Y., Sakaguchi Y., Kusumoto T., Kusumoto H., and Sugimachi K. Species differences in substrate specificity of pyrimidine nucleoside phosphorylase. J Surg Oncol 42 (1989) 184-186
-
(1989)
J Surg Oncol
, vol.42
, pp. 184-186
-
-
Maehara, Y.1
Sakaguchi, Y.2
Kusumoto, T.3
Kusumoto, H.4
Sugimachi, K.5
-
29
-
-
0035292622
-
[Expression and pathophysiologic features of orotate phosphoribosyl transferase activity (OPRT) in gastric carcinoma]
-
Ochiai T., Sugitani M., Nishimura K., Noguchi H., Watanabe T., Sengoku H., Kihara A., and Okano M. [Expression and pathophysiologic features of orotate phosphoribosyl transferase activity (OPRT) in gastric carcinoma]. Gan To Kagaku Ryoho 28 (2001) 345-350
-
(2001)
Gan To Kagaku Ryoho
, vol.28
, pp. 345-350
-
-
Ochiai, T.1
Sugitani, M.2
Nishimura, K.3
Noguchi, H.4
Watanabe, T.5
Sengoku, H.6
Kihara, A.7
Okano, M.8
-
30
-
-
0036516114
-
Correlation between clinical pathophysiologic factors and expression of orotate phosphoribosyl transferase activity (OPRT), thymidylate synthase (TS), and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer
-
Ochiai T., Sugitani M., Nishimura K., et al. Correlation between clinical pathophysiologic factors and expression of orotate phosphoribosyl transferase activity (OPRT), thymidylate synthase (TS), and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer. Gan To Kagaku Ryoho 29 (2002) 413-420
-
(2002)
Gan To Kagaku Ryoho
, vol.29
, pp. 413-420
-
-
Ochiai, T.1
Sugitani, M.2
Nishimura, K.3
-
31
-
-
3242720475
-
Choice of chemotherapeutic drugs for colorectal cancers by DPD and OPRT activities in cancer tissues
-
Takemura M., Osugi H., Lee S., et al. Choice of chemotherapeutic drugs for colorectal cancers by DPD and OPRT activities in cancer tissues. Gan To Kagaku Ryoho 31 (2004) 1053-1056
-
(2004)
Gan To Kagaku Ryoho
, vol.31
, pp. 1053-1056
-
-
Takemura, M.1
Osugi, H.2
Lee, S.3
-
32
-
-
0242658929
-
Both gene expression for orotate phosphoribosyl transferase and its ratio for dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer
-
Ichikawa W., Uetake H., Shirota Y., et al. Both gene expression for orotate phosphoribosyl transferase and its ratio for dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer. Br J Cancer 89 (2003) 1486-1492
-
(2003)
Br J Cancer
, vol.89
, pp. 1486-1492
-
-
Ichikawa, W.1
Uetake, H.2
Shirota, Y.3
-
33
-
-
0036934486
-
Predicting 5-FU sensitivity using human colorectal cancer specimens: comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activities with in vitro chemotherapy to 5-FU
-
Isshi K., Sakuyama T., Gen T., et al. Predicting 5-FU sensitivity using human colorectal cancer specimens: comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activities with in vitro chemotherapy to 5-FU. Int J Clin Oncol 7 (2002) 335-342
-
(2002)
Int J Clin Oncol
, vol.7
, pp. 335-342
-
-
Isshi, K.1
Sakuyama, T.2
Gen, T.3
-
34
-
-
0031722179
-
High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouraicl
-
Metzger R., Danenberg K., Leichman C.G., et al. High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouraicl. Clin Cancer Res 4 (1998) 2371-2376
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2371-2376
-
-
Metzger, R.1
Danenberg, K.2
Leichman, C.G.3
-
35
-
-
0032797555
-
Increased cytotoxicity and by stander effect of 5-fluorouracil and 5-deoxy-5-fluorouracil in human colorectal cancer cells transfected with thymidine phosphorylase
-
Evrard A., Cuq P., Ciccolini J., Vian L., and Cano J.P. Increased cytotoxicity and by stander effect of 5-fluorouracil and 5-deoxy-5-fluorouracil in human colorectal cancer cells transfected with thymidine phosphorylase. Br J Cancer 80 (1999) 1726-1733
-
(1999)
Br J Cancer
, vol.80
, pp. 1726-1733
-
-
Evrard, A.1
Cuq, P.2
Ciccolini, J.3
Vian, L.4
Cano, J.P.5
-
36
-
-
0029102247
-
5-Ethoxy-2′-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fuorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression
-
Schwartz E.L., Baptiste N., Megati S., Wadler S., and Otter B.A. 5-Ethoxy-2′-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fuorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression. Cancer Res 55 (1995) 3543-3550
-
(1995)
Cancer Res
, vol.55
, pp. 3543-3550
-
-
Schwartz, E.L.1
Baptiste, N.2
Megati, S.3
Wadler, S.4
Otter, B.A.5
-
37
-
-
0027125627
-
Angiogenic factor
-
Furukawa T., Yoshimura A., Sumizawa T., Haraguchi M., Akiyama S., Fukui K., Ishizawa M., and Yamada Y. Angiogenic factor. Nature 356 (1992) 668
-
(1992)
Nature
, vol.356
, pp. 668
-
-
Furukawa, T.1
Yoshimura, A.2
Sumizawa, T.3
Haraguchi, M.4
Akiyama, S.5
Fukui, K.6
Ishizawa, M.7
Yamada, Y.8
|