메뉴 건너뛰기




Volumn 52, Issue 66, 2005, Pages 1715-1721

Clinical role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in colorectal cancer treated with postoperative fluoropyrimidine

Author keywords

Colorectal cancer; Dihydropyrimidine dehydrogenase; Human; Immunohistochemistry; Thymidine phosphorylase

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL DERIVATIVE; MONOCLONAL ANTIBODY; THYMIDINE PHOSPHORYLASE; UFT;

EID: 28544436512     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (13)

References (38)
  • 1
    • 0028351657 scopus 로고
    • Chemotherapy for colorectal cancer
    • Moertel CG: Chemotherapy for colorectal cancer. N Engl J Med 1994; 330:1136-1142.
    • (1994) N Engl J Med , vol.330 , pp. 1136-1142
    • Moertel, C.G.1
  • 2
    • 0026721532 scopus 로고
    • Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
    • Advanced Colorectal Cancer Meta-analysis Project: Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate. J Clin Oncol 1992; 10:896-903.
    • (1992) J Clin Oncol , vol.10 , pp. 896-903
  • 3
    • 0020530463 scopus 로고
    • Activation of 5'-deoxy-5-flurorouridine by thymidine phosphorylase in human tumor tissues
    • Kono H, Kara Y, Sugita S, Karube Y, Matsushima Y, Ishitsuka H: Activation of 5'-deoxy-5-flurorouridine by thymidine phosphorylase in human tumor tissues. Chem Pharm Bull 1983; 31:175-178.
    • (1983) Chem Pharm Bull , vol.31 , pp. 175-178
    • Kono, H.1    Kara, Y.2    Sugita, S.3    Karube, Y.4    Matsushima, Y.5    Ishitsuka, H.6
  • 4
    • 0023187085 scopus 로고
    • Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile
    • Heggie GD, Sommadossi JP, Cross DS, Husster WJ, Diasio RB: Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile. Cancer Res 1987; 47:2203-2206.
    • (1987) Cancer Res , vol.47 , pp. 2203-2206
    • Heggie, G.D.1    Sommadossi, J.P.2    Cross, D.S.3    Husster, W.J.4    Diasio, R.B.5
  • 6
    • 0034000054 scopus 로고    scopus 로고
    • Characterization of dihydropyrimidine dehydrogenase in immunohistochemistry in colon carcinoma, and correlation between immunohistochemical score and protein level or messenger RNA expression
    • Takenoue T, Kitayama J, Takei Y, Umetani N, Matsuda K, Nita ME, Hatano K, Tsuruo T, Nagawa H: Characterization of dihydropyrimidine dehydrogenase in immunohistochemistry in colon carcinoma, and correlation between immunohistochemical score and protein level or messenger RNA expression. Ann Oncol 2000; 11:273-279.
    • (2000) Ann Oncol , vol.11 , pp. 273-279
    • Takenoue, T.1    Kitayama, J.2    Takei, Y.3    Umetani, N.4    Matsuda, K.5    Nita, M.E.6    Hatano, K.7    Tsuruo, T.8    Nagawa, H.9
  • 9
    • 0035179277 scopus 로고    scopus 로고
    • Development and characterization of 1C6-203, a new monoclonal antibody specific to the human thymidine phosphorylase
    • Kono T, Nishida M, Inagaki N, Tanaka Y, Yoneda M, Kasai S: Development and characterization of 1C6-203, a new monoclonal antibody specific to the human thymidine phosphorylase. J Histochem Cytochem 2001; 49:131-137.
    • (2001) J Histochem Cytochem , vol.49 , pp. 131-137
    • Kono, T.1    Nishida, M.2    Inagaki, N.3    Tanaka, Y.4    Yoneda, M.5    Kasai, S.6
  • 10
    • 0036257036 scopus 로고    scopus 로고
    • Prognostic value of thymidine phosphorylase/PD-ECGF in advanced colorectal cancer after surgery: Evaluation with a new monoclonal antibody
    • Tokunaga Y, Hosogi H, Hoppou T, Nakagami M, Tokuka A, Ohsumi K: Prognostic value of thymidine phosphorylase/PD-ECGF in advanced colorectal cancer after surgery: Evaluation with a new monoclonal antibody. Surgery 2002; 131:541-547.
    • (2002) Surgery , vol.131 , pp. 541-547
    • Tokunaga, Y.1    Hosogi, H.2    Hoppou, T.3    Nakagami, M.4    Tokuka, A.5    Ohsumi, K.6
  • 11
    • 0037862137 scopus 로고    scopus 로고
    • Prognostic effects of dihydropyrimidine dehydrogenase in advanced colorectal cancer after surgery: Immunohistochemistry using a new monoclonal antibody
    • Tokunaga Y, Nakagami M, Tokuka A, Ohsumi K: Prognostic effects of dihydropyrimidine dehydrogenase in advanced colorectal cancer after surgery: Immunohistochemistry using a new monoclonal antibody. Anticancer Res 2003; 23:1763-1768.
    • (2003) Anticancer Res , vol.23 , pp. 1763-1768
    • Tokunaga, Y.1    Nakagami, M.2    Tokuka, A.3    Ohsumi, K.4
  • 13
    • 0019423594 scopus 로고
    • Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures
    • Hsu SM, Raine L, Fanger H: Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981; 29:577-580.
    • (1981) J Histochem Cytochem , vol.29 , pp. 577-580
    • Hsu, S.M.1    Raine, L.2    Fanger, H.3
  • 14
    • 0029006332 scopus 로고
    • Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: An immunohistochemical study
    • Fox SB, Moghaddam A, Westwood M, Turley H, Bicknell R, Gatter KC, Harris AL: Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: an immunohistochemical study. J Pathol 1995; 176:183-190.
    • (1995) J Pathol , vol.176 , pp. 183-190
    • Fox, S.B.1    Moghaddam, A.2    Westwood, M.3    Turley, H.4    Bicknell, R.5    Gatter, K.C.6    Harris, A.L.7
  • 15
    • 0024852342 scopus 로고
    • Catalyzed reporter deposition, a novel method of signal amplification: Application to immunoassays
    • Bobrow M, Harris TD, Shaughnessy KJ, Litt GJ: Catalyzed reporter deposition, a novel method of signal amplification: Application to immunoassays. J Immunol Meth 1989; 125:279-284.
    • (1989) J Immunol Meth , vol.125 , pp. 279-284
    • Bobrow, M.1    Harris, T.D.2    Shaughnessy, K.J.3    Litt, G.J.4
  • 16
    • 0025848382 scopus 로고
    • The taming of immunohistochemistry: The new era of quality control
    • Herman GE, Alfont EA: The taming of immunohistochemistry: The new era of quality control. Biotech Histochem 1991; 66:194-199.
    • (1991) Biotech Histochem , vol.66 , pp. 194-199
    • Herman, G.E.1    Alfont, E.A.2
  • 18
    • 0023464656 scopus 로고
    • Statistical methods in cancer research. Volume II: The design and analysis of cohort studies
    • Breslow NE, Day NE: Statistical methods in cancer research. Volume II: The design and analysis of cohort studies. IARC Sci Publ 1987; pp. 1-406.
    • (1987) IARC Sci Publ , pp. 1-406
    • Breslow, N.E.1    Day, N.E.2
  • 19
    • 0022656553 scopus 로고
    • Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouracil in relation to drug-metabolizing enzymes
    • Peters GJ, Laurensse E, Leyva A, et al: Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouracil in relation to drug-metabolizing enzymes. Cancer Res 1986; 46:20-28.
    • (1986) Cancer Res , vol.46 , pp. 20-28
    • Peters, G.J.1    Laurensse, E.2    Leyva, A.3
  • 20
    • 0026045814 scopus 로고
    • A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa
    • Peters GJ, Groeningen CJ, Laurencsse EJ, Pinedo HM: A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa. Cancer 1991; 68:1903-1909.
    • (1991) Cancer , vol.68 , pp. 1903-1909
    • Peters, G.J.1    Groeningen, C.J.2    Laurencsse, E.J.3    Pinedo, H.M.4
  • 22
    • 0031722179 scopus 로고    scopus 로고
    • High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil
    • Metzger R, Danenberg K, Leichman CG, et al: High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. Clin Cancer Res 1998; 4:2371-2376.
    • (1998) Clin Cancer Res , vol.4 , pp. 2371-2376
    • Metzger, R.1    Danenberg, K.2    Leichman, C.G.3
  • 23
    • 0032797555 scopus 로고    scopus 로고
    • Increased cytotoxicity and by Stander effect of 5-fluorouracil and 5-deoxy-5-fluorouracil in human colorectal cancer cells transfected with thymidine phosphorylase
    • Evrard A, Cuq P, Ciccolini J, Vian L, Cano JP: Increased cytotoxicity and by Stander effect of 5-fluorouracil and 5-deoxy-5-fluorouracil in human colorectal cancer cells transfected with thymidine phosphorylase. Br J Cancer 1999; 80:1726-1733.
    • (1999) Br J Cancer , vol.80 , pp. 1726-1733
    • Evrard, A.1    Cuq, P.2    Ciccolini, J.3    Vian, L.4    Cano, J.P.5
  • 24
    • 0029102247 scopus 로고
    • 5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression
    • Schwartz EL, Baptiste N, Megati S, Wadler S, Otter BA: 5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression. Cancer Res 1995; 55:3543-3550.
    • (1995) Cancer Res , vol.55 , pp. 3543-3550
    • Schwartz, E.L.1    Baptiste, N.2    Megati, S.3    Wadler, S.4    Otter, B.A.5
  • 25
    • 0036934486 scopus 로고    scopus 로고
    • Predicting 5-FU sensitivity using human colorectal cancer specimens: Comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphorybosyl transferase activities with in vitro chemotherapy to 5-FU
    • Isshi K, Sakuyama T, Gen T, Nakamura Y, Kuroda T, Katuyama T, Maekawa Y: Predicting 5-FU sensitivity using human colorectal cancer specimens: comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphorybosyl transferase activities with in vitro chemotherapy to 5-FU. Int J Clin Oncol 2002; 7:335-342.
    • (2002) Int J Clin Oncol , vol.7 , pp. 335-342
    • Isshi, K.1    Sakuyama, T.2    Gen, T.3    Nakamura, Y.4    Kuroda, T.5    Katuyama, T.6    Maekawa, Y.7
  • 26
    • 0037660429 scopus 로고    scopus 로고
    • Relationships between the expression of thymidine synthase, dehydropyrimidine dehydrogenase, and orotate phophorybosyltransferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma
    • Fujii R, Seshimo A, Kameoka S: Relationships between the expression of thymidine synthase, dehydropyrimidine dehydrogenase, and orotate phophorybosyltransferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma. Int J Clin Oncol 2003; 8:72-78.
    • (2003) Int J Clin Oncol , vol.8 , pp. 72-78
    • Fujii, R.1    Seshimo, A.2    Kameoka, S.3
  • 28
    • 0037089505 scopus 로고    scopus 로고
    • Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines
    • Cao D, Russel RL, Zhang D, Leffert JJ, Pizzorno G: Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines. Cancer Res 2002; 62:2313-2317.
    • (2002) Cancer Res , vol.62 , pp. 2313-2317
    • Cao, D.1    Russel, R.L.2    Zhang, D.3    Leffert, J.J.4    Pizzorno, G.5
  • 29
    • 0037325801 scopus 로고    scopus 로고
    • Correlation between clinicopathologic factors and kinetics of metabolic enzymes for 5-fluorouracil given to patients colon carcinoma by two different dosage regimens
    • Katsumata K, Tomioka H, Sumi T, Yamashita S, Takagi M, Kato F, Nakamura R, Koyanagi Y, Aoki T, Kato K: Correlation between clinicopathologic factors and kinetics of metabolic enzymes for 5-fluorouracil given to patients colon carcinoma by two different dosage regimens. Cancer Chemother Pharmacol 2003; 51:155-160.
    • (2003) Cancer Chemother Pharmacol , vol.51 , pp. 155-160
    • Katsumata, K.1    Tomioka, H.2    Sumi, T.3    Yamashita, S.4    Takagi, M.5    Kato, F.6    Nakamura, R.7    Koyanagi, Y.8    Aoki, T.9    Kato, K.10
  • 31
    • 0013447478 scopus 로고
    • Metabolism of 5-fluorouracil in tumor cell
    • Uchida M, Nakamura T: Metabolism of 5-fluorouracil in tumor cell. Pur Pyrim Metab 1991; 15:122-129.
    • (1991) Pur Pyrim Metab , vol.15 , pp. 122-129
    • Uchida, M.1    Nakamura, T.2
  • 33
    • 0037312517 scopus 로고    scopus 로고
    • Combination of dihydropyrimidine dehydrogenase and thymidylate synthase gene expression in primary tumors as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer
    • Ichikawa W, Uetake H, Shirota Y, Yamada H, Nishi N, Nihei Z, Sugihara K, Hirayama R: Combination of dihydropyrimidine dehydrogenase and thymidylate synthase gene expression in primary tumors as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer. Clin Cancer Res 2003; 9:786-791.
    • (2003) Clin Cancer Res , vol.9 , pp. 786-791
    • Ichikawa, W.1    Uetake, H.2    Shirota, Y.3    Yamada, H.4    Nishi, N.5    Nihei, Z.6    Sugihara, K.7    Hirayama, R.8
  • 36
    • 0033995850 scopus 로고    scopus 로고
    • Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method
    • Takenoue T, Nagawa H, Matsuda K, Fujii S, Nita ME, Hatano K, Kitayama J, Tsuruo T, Muto T: Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method. Ann Surg Oncol 2000; 7:193-198.
    • (2000) Ann Surg Oncol , vol.7 , pp. 193-198
    • Takenoue, T.1    Nagawa, H.2    Matsuda, K.3    Fujii, S.4    Nita, M.E.5    Hatano, K.6    Kitayama, J.7    Tsuruo, T.8    Muto, T.9
  • 38
    • 0036582566 scopus 로고    scopus 로고
    • Thymidine phosphorylase and dihydropyridine dehydrogenase levels in primary colorectal cancer shows a relationship to clinical effect of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy
    • Nishimura G, Terada I, Kobayashi T, Ninomiya I, Kitagawa H, Fushida S, Fujimura T, Kayahara M, Shimizu K, Ohta T, Miwa K: Thymidine phosphorylase and dihydropyridine dehydrogenase levels in primary colorectal cancer shows a relationship to clinical effect of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy. Oncology Reports 2002; 9:479-482.
    • (2002) Oncology Reports , vol.9 , pp. 479-482
    • Nishimura, G.1    Terada, I.2    Kobayashi, T.3    Ninomiya, I.4    Kitagawa, H.5    Fushida, S.6    Fujimura, T.7    Kayahara, M.8    Shimizu, K.9    Ohta, T.10    Miwa, K.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.