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Volumn 49, Issue 9, 2007, Pages 963-971

Carvedilol Protects Better Against Vascular Events Than Metoprolol in Heart Failure. Results From COMET

Author keywords

[No Author keywords available]

Indexed keywords

CARVEDILOL; METOPROLOL;

EID: 33847403173     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2006.10.059     Document Type: Article
Times cited : (58)

References (33)
  • 1
    • 0029937949 scopus 로고    scopus 로고
    • The effect of carvedilol on morbidity and mortality in patients with chronic heart failure
    • Packer M., Bristow M.R., Cohn J.N., et al. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Engl J Med 334 (1996) 1349-1355
    • (1996) N Engl J Med , vol.334 , pp. 1349-1355
    • Packer, M.1    Bristow, M.R.2    Cohn, J.N.3
  • 2
    • 0033514046 scopus 로고    scopus 로고
    • The Cardiac Insufficiency Bisoprolol Study II (CIBIS II): a randomised trial
    • CIBIS II Investigators and Committees
    • CIBIS II Investigators and Committees. The Cardiac Insufficiency Bisoprolol Study II (CIBIS II): a randomised trial. Lancet 353 (1999) 9-13
    • (1999) Lancet , vol.353 , pp. 9-13
  • 3
    • 0033549290 scopus 로고    scopus 로고
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in congestive heart failure (MERIT-HF)
    • MERIT-HF Study Group
    • MERIT-HF Study Group. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in congestive heart failure (MERIT-HF). Lancet 353 (1999) 2001-2007
    • (1999) Lancet , vol.353 , pp. 2001-2007
  • 4
    • 0035978763 scopus 로고    scopus 로고
    • Effect of carvedilol on survival in severe chronic heart failure
    • Packer M., Coats A.J.S., Fowler M.B., et al. Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med 344 (2001) 1651-1658
    • (2001) N Engl J Med , vol.344 , pp. 1651-1658
    • Packer, M.1    Coats, A.J.S.2    Fowler, M.B.3
  • 5
    • 0030997947 scopus 로고    scopus 로고
    • Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Australia-New Zealand Heart Failure Research Collaborative Group
    • Doughty R.N., Whalley G.A., Gamble G., et al. Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Australia-New Zealand Heart Failure Research Collaborative Group. J Am Coll Cardiol 29 (1997) 1060-1066
    • (1997) J Am Coll Cardiol , vol.29 , pp. 1060-1066
    • Doughty, R.N.1    Whalley, G.A.2    Gamble, G.3
  • 7
    • 3142776467 scopus 로고    scopus 로고
    • Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial
    • Poole-Wilson P.A., Swedberg K., Cleland J.G.F., et al. Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial. Lancet 362 (2003) 7-13
    • (2003) Lancet , vol.362 , pp. 7-13
    • Poole-Wilson, P.A.1    Swedberg, K.2    Cleland, J.G.F.3
  • 8
    • 8444235096 scopus 로고    scopus 로고
    • Carvedilol but not metoprolol reduces β-adrenergic responsiveness after complete elimination from plasma in vivo
    • Kindermann M., Maack C., Schaller S., et al. Carvedilol but not metoprolol reduces β-adrenergic responsiveness after complete elimination from plasma in vivo. Circulation 109 (2004) 3182-3190
    • (2004) Circulation , vol.109 , pp. 3182-3190
    • Kindermann, M.1    Maack, C.2    Schaller, S.3
  • 9
    • 0030610120 scopus 로고    scopus 로고
    • Beta 2-adrenergic receptor antagonists protect against ventricular fibrillation. In vivo and in vitro evidence for enhanced sensitivity to beta 2-adrenergic stimulation in animals susceptible to sudden death
    • Billman G.E., Castillo L.C., Hensley J., Hohl C.M., and Altschud R.A. Beta 2-adrenergic receptor antagonists protect against ventricular fibrillation. In vivo and in vitro evidence for enhanced sensitivity to beta 2-adrenergic stimulation in animals susceptible to sudden death. Circulation 96 (1997) 1914-1922
    • (1997) Circulation , vol.96 , pp. 1914-1922
    • Billman, G.E.1    Castillo, L.C.2    Hensley, J.3    Hohl, C.M.4    Altschud, R.A.5
  • 10
    • 0034602839 scopus 로고    scopus 로고
    • β2-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis
    • Du X.J., Autelitano D., Dilley R.J., Wang B., Dart A.M., and Woodcock E.A. β2-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis. Circulation 101 (2000) 71-77
    • (2000) Circulation , vol.101 , pp. 71-77
    • Du, X.J.1    Autelitano, D.2    Dilley, R.J.3    Wang, B.4    Dart, A.M.5    Woodcock, E.A.6
  • 11
    • 0030431042 scopus 로고    scopus 로고
    • Alpha-1 adrenoceptor subtypes involved in mediating adrenergically induced antinatriuresis and antidiuresis in two kidney, one clip Goldblatt and deoxycorticosterone acetate-salt hypertensive rats
    • Sattar M.A., and Johns E.J. Alpha-1 adrenoceptor subtypes involved in mediating adrenergically induced antinatriuresis and antidiuresis in two kidney, one clip Goldblatt and deoxycorticosterone acetate-salt hypertensive rats. J Pharmcol Exp Ther 277 (1996) 245-252
    • (1996) J Pharmcol Exp Ther , vol.277 , pp. 245-252
    • Sattar, M.A.1    Johns, E.J.2
  • 12
    • 0036623903 scopus 로고    scopus 로고
    • Rationale and design of the carvedilol or metoprolol European trial in patients with chronic heart failure: COMET
    • Poole-Wilson P.A., Cleland J.G., Di Lenarda A., et al. Rationale and design of the carvedilol or metoprolol European trial in patients with chronic heart failure: COMET. Eur J Heart Fail 4 (2002) 321-329
    • (2002) Eur J Heart Fail , vol.4 , pp. 321-329
    • Poole-Wilson, P.A.1    Cleland, J.G.2    Di Lenarda, A.3
  • 13
    • 0032693742 scopus 로고    scopus 로고
    • Long-term effects of carvedilol in idiopathic dilated cardiomyopathy with persistent left ventricular dysfunction despite chronic metoprolol. The Heart-Muscle-Disease Study Group
    • Di Lenarda A., Sabbadini G., Salvatore L., et al. Long-term effects of carvedilol in idiopathic dilated cardiomyopathy with persistent left ventricular dysfunction despite chronic metoprolol. The Heart-Muscle-Disease Study Group. J Am Coll Cardiol 33 (1999) 1926-1934
    • (1999) J Am Coll Cardiol , vol.33 , pp. 1926-1934
    • Di Lenarda, A.1    Sabbadini, G.2    Salvatore, L.3
  • 14
    • 0033230514 scopus 로고    scopus 로고
    • Beta-blockade in heart failure. A comparison of carvedilol with metoprolol
    • Sanderson J.E., Chan S.K.W., Yip G., et al. Beta-blockade in heart failure. A comparison of carvedilol with metoprolol. J Am Coll Cardiol 34 (1999) 1522-1528
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1522-1528
    • Sanderson, J.E.1    Chan, S.K.W.2    Yip, G.3
  • 15
    • 0034255060 scopus 로고    scopus 로고
    • Differential effects of beta-blockers in patients with heart failure. A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol
    • Metra M., Gibbini R., Nodari S., Boldi E., Modena M.G., and Dei Cas L. Differential effects of beta-blockers in patients with heart failure. A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol. Circulation 102 (2002) 546-551
    • (2002) Circulation , vol.102 , pp. 546-551
    • Metra, M.1    Gibbini, R.2    Nodari, S.3    Boldi, E.4    Modena, M.G.5    Dei Cas, L.6
  • 16
    • 0035370722 scopus 로고    scopus 로고
    • Comparative effects or carvedilol and metoprolol on left ventricular ejection fraction in heart failure: a meta-analysis
    • Packer M., Antonopoulos G.V., Berlin J.A., Chittams J., Konstam M.A., and Udelson J.E. Comparative effects or carvedilol and metoprolol on left ventricular ejection fraction in heart failure: a meta-analysis. Am Heart J 141 (2001) 899-907
    • (2001) Am Heart J , vol.141 , pp. 899-907
    • Packer, M.1    Antonopoulos, G.V.2    Berlin, J.A.3    Chittams, J.4    Konstam, M.A.5    Udelson, J.E.6
  • 17
    • 13544262459 scopus 로고    scopus 로고
    • Antiarrhythmic effect of carvedilol after acute myocardial infarction. Results of the carvedilol post-infarct survival control in left ventricular dysfunction (CAPRICORN) trial
    • McMurray J., Kober I., Robertson M., et al. Antiarrhythmic effect of carvedilol after acute myocardial infarction. Results of the carvedilol post-infarct survival control in left ventricular dysfunction (CAPRICORN) trial. J Am Coll Cardiol 45 (2005) 525-530
    • (2005) J Am Coll Cardiol , vol.45 , pp. 525-530
    • McMurray, J.1    Kober, I.2    Robertson, M.3
  • 18
    • 0034538799 scopus 로고    scopus 로고
    • Divergent effects of different beta-blocking agents on endothelin-dependent vasodilatation in the human forearm
    • Von zur Muhlen B., Millgard J., and Lind L. Divergent effects of different beta-blocking agents on endothelin-dependent vasodilatation in the human forearm. Blood Press 9 (2000) 287-292
    • (2000) Blood Press , vol.9 , pp. 287-292
    • Von zur Muhlen, B.1    Millgard, J.2    Lind, L.3
  • 19
    • 0041857863 scopus 로고    scopus 로고
    • Comparative effects of carvedilol and metoprolol on regional vascular responses to adrenergic stimuli in normal subjects and patients with chronic heart failure
    • Hryniewicz K., Androne A.S., Hudaihed A., and Katz S.D. Comparative effects of carvedilol and metoprolol on regional vascular responses to adrenergic stimuli in normal subjects and patients with chronic heart failure. Circulation 108 (2003) 971-976
    • (2003) Circulation , vol.108 , pp. 971-976
    • Hryniewicz, K.1    Androne, A.S.2    Hudaihed, A.3    Katz, S.D.4
  • 20
    • 0034021683 scopus 로고    scopus 로고
    • Disparate effects of carvedilol versus metoprolol treatment of stroke-prone spontaneously hypertensive rats on endothelial function of resistance arteries
    • Intengan H.D., and Schiffrin E.L. Disparate effects of carvedilol versus metoprolol treatment of stroke-prone spontaneously hypertensive rats on endothelial function of resistance arteries. J Cardiovasc Pharmacol 35 (2000) 763-768
    • (2000) J Cardiovasc Pharmacol , vol.35 , pp. 763-768
    • Intengan, H.D.1    Schiffrin, E.L.2
  • 21
    • 0033766282 scopus 로고    scopus 로고
    • Carvedilol improves endothelium-dependent dilatation in patients with coronary artery disease
    • Matsuda Y., Akita H., Terashima M., Shiga N., Kanazawa K., and Yokoyama M. Carvedilol improves endothelium-dependent dilatation in patients with coronary artery disease. Am Heart J 140 (2000) 753-759
    • (2000) Am Heart J , vol.140 , pp. 753-759
    • Matsuda, Y.1    Akita, H.2    Terashima, M.3    Shiga, N.4    Kanazawa, K.5    Yokoyama, M.6
  • 22
    • 0029092047 scopus 로고
    • Carvedilol, a new beta-adrenoceptor blocker antihypertensive drug, protects against free-radical-induced endothelial dysfunction
    • Lopez B.L., Christopher T.A., Yue T.L., Ruffolo R., Feuerstein G.Z., and Ma X.L. Carvedilol, a new beta-adrenoceptor blocker antihypertensive drug, protects against free-radical-induced endothelial dysfunction. Pharmacology 51 (1995) 165-173
    • (1995) Pharmacology , vol.51 , pp. 165-173
    • Lopez, B.L.1    Christopher, T.A.2    Yue, T.L.3    Ruffolo, R.4    Feuerstein, G.Z.5    Ma, X.L.6
  • 23
    • 0034613212 scopus 로고    scopus 로고
    • Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model
    • Gao F., Chen J., Lopez B.L., et al. Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model. Eur J Pharmacol 406 (2000) 109-116
    • (2000) Eur J Pharmacol , vol.406 , pp. 109-116
    • Gao, F.1    Chen, J.2    Lopez, B.L.3
  • 24
    • 0030430050 scopus 로고    scopus 로고
    • Carvedilol, a new beta-adrenoceptor blocker and free radical scavenger attenuates myocardial ischemia reperfusion injury in hypercholesterolemic rabbits
    • Ma X.L., Yue T.L., Lopez B.L., et al. Carvedilol, a new beta-adrenoceptor blocker and free radical scavenger attenuates myocardial ischemia reperfusion injury in hypercholesterolemic rabbits. J Pharmacol Exp Ther 277 (1996) 128-136
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 128-136
    • Ma, X.L.1    Yue, T.L.2    Lopez, B.L.3
  • 25
    • 0031706613 scopus 로고    scopus 로고
    • Comparative effects of carvedilol and metoprolol on cardiac ischemia-reperfusion injury
    • Khandoudi N., Percevault-Albadine J., and Bril A. Comparative effects of carvedilol and metoprolol on cardiac ischemia-reperfusion injury. J Cardiovasc Pharmacol 32 (1998) 443-451
    • (1998) J Cardiovasc Pharmacol , vol.32 , pp. 443-451
    • Khandoudi, N.1    Percevault-Albadine, J.2    Bril, A.3
  • 26
    • 0036998602 scopus 로고    scopus 로고
    • Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xanthine oxidase-what role in myocardial ischemia and reperfusion?
    • Oliveira P.J., Rolo A.P., Monteiro P., Goncalves L., Palmeira C.M., and Moreno A.J. Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xanthine oxidase-what role in myocardial ischemia and reperfusion?. Rev Port Cardiol 21 (2002) 1447-1455
    • (2002) Rev Port Cardiol , vol.21 , pp. 1447-1455
    • Oliveira, P.J.1    Rolo, A.P.2    Monteiro, P.3    Goncalves, L.4    Palmeira, C.M.5    Moreno, A.J.6
  • 27
    • 2942602676 scopus 로고    scopus 로고
    • Beta-adrenoceptor blocker carvedilol provides cardioprotection via an adenosine-dependent mechanism in ischemic canine hearts
    • Asanuma H., Minamino T., Sanada S., et al. Beta-adrenoceptor blocker carvedilol provides cardioprotection via an adenosine-dependent mechanism in ischemic canine hearts. Circulation 109 (2004) 2773-2779
    • (2004) Circulation , vol.109 , pp. 2773-2779
    • Asanuma, H.1    Minamino, T.2    Sanada, S.3
  • 28
    • 0033979444 scopus 로고    scopus 로고
    • Carvedilol prevents epinephrine-induced apoptosis in human coronary artery endothelial cells: modulation of Fas/Fas ligand and caspase-3 pathway
    • Romeo F., Li D., Shi M., and Mehta J.L. Carvedilol prevents epinephrine-induced apoptosis in human coronary artery endothelial cells: modulation of Fas/Fas ligand and caspase-3 pathway. Cardiovasc Res 45 (2000) 788-794
    • (2000) Cardiovasc Res , vol.45 , pp. 788-794
    • Romeo, F.1    Li, D.2    Shi, M.3    Mehta, J.L.4
  • 29
    • 0033662177 scopus 로고    scopus 로고
    • Congestive heart failure induces endothelial cell apoptosis: protective role of carvedilol
    • Rossig L., Haendeler J., Mallat Z., et al. Congestive heart failure induces endothelial cell apoptosis: protective role of carvedilol. J Am Coll Cardiol 36 (2000) 2081-2089
    • (2000) J Am Coll Cardiol , vol.36 , pp. 2081-2089
    • Rossig, L.1    Haendeler, J.2    Mallat, Z.3
  • 30
    • 8344234111 scopus 로고    scopus 로고
    • Carvedilol inhibits tumor necrosis factor-alpha-induced endothelial transcription factor activation, adhesion molecule expression and adhesiveness to human mononuclear cells
    • Chen J.W., Lin F.Y., Chen Y.H., Wu T., Chen Y.L., and Lin S.J. Carvedilol inhibits tumor necrosis factor-alpha-induced endothelial transcription factor activation, adhesion molecule expression and adhesiveness to human mononuclear cells. Arterioscler Thromb Vasc Biol 24 (2004) 2075-2081
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2075-2081
    • Chen, J.W.1    Lin, F.Y.2    Chen, Y.H.3    Wu, T.4    Chen, Y.L.5    Lin, S.J.6
  • 31
    • 0033919623 scopus 로고    scopus 로고
    • Differential effects of carvedilol on norepinephrine release in normoxic and ischemic heart
    • Kurz T., Richardt D., Gorge B., et al. Differential effects of carvedilol on norepinephrine release in normoxic and ischemic heart. J Cardiovasc Pharmacol 36 (2000) 96-100
    • (2000) J Cardiovasc Pharmacol , vol.36 , pp. 96-100
    • Kurz, T.1    Richardt, D.2    Gorge, B.3
  • 32
    • 27544458100 scopus 로고    scopus 로고
    • Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial
    • Metra M., Torp-Pedersen C., Swedberg K.S., et al. Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial. Eur Heart J 26 (2005) 2259-2268
    • (2005) Eur Heart J , vol.26 , pp. 2259-2268
    • Metra, M.1    Torp-Pedersen, C.2    Swedberg, K.S.3
  • 33
    • 0037626650 scopus 로고    scopus 로고
    • Myocardial viability as a determinant of the ejection fraction response to carvedilol in patients with heart failure (CHRISTMAS trial): randomised, controlled trial
    • Cleland J.G.F., Pennell D.J., Ray S.G., et al. Myocardial viability as a determinant of the ejection fraction response to carvedilol in patients with heart failure (CHRISTMAS trial): randomised, controlled trial. Lancet 362 (2003) 14-21
    • (2003) Lancet , vol.362 , pp. 14-21
    • Cleland, J.G.F.1    Pennell, D.J.2    Ray, S.G.3


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