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Volumn 53, Issue 2, 2007, Pages 326-333

Biomarkers of folate and vitamin B12 are related in blood and cerebrospinal fluid

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYANOCOBALAMIN; CYSTATHIONINE; FOLIC ACID; HOMOCYSTEINE; METHYLMALONIC ACID; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

EID: 33847380640     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2006.076448     Document Type: Article
Times cited : (60)

References (40)
  • 1
    • 0032713688 scopus 로고    scopus 로고
    • Brain function in the elderly: Role of vitamin B12 and folate
    • Weir DG, Scott JM. Brain function in the elderly: role of vitamin B12 and folate. Br Med Bull 1999;55:669-82.
    • (1999) Br Med Bull , vol.55 , pp. 669-682
    • Weir, D.G.1    Scott, J.M.2
  • 2
    • 0026045338 scopus 로고
    • Betaine-homocysteine methyltransferase: Organ distribution in man, pig and rat and subcellular distribution in the rat
    • McKeever MP, Weir DG, Molloy A, Scott JM. Betaine-homocysteine methyltransferase: organ distribution in man, pig and rat and subcellular distribution in the rat. Clin Sci (Lond) 1991;81:551-6.
    • (1991) Clin Sci (Lond) , vol.81 , pp. 551-556
    • McKeever, M.P.1    Weir, D.G.2    Molloy, A.3    Scott, J.M.4
  • 4
    • 0018858068 scopus 로고
    • Methionine recycling in brain: A role for folates and vitamin B-12
    • Spector R, Coakley G, Blakely R. Methionine recycling in brain: a role for folates and vitamin B-12. J Neurochem 1980;34:132-7.
    • (1980) J Neurochem , vol.34 , pp. 132-137
    • Spector, R.1    Coakley, G.2    Blakely, R.3
  • 7
    • 5644250686 scopus 로고    scopus 로고
    • Homocysteine and cognitive function in elderly people
    • Garcia A, Zanibbi K. Homocysteine and cognitive function in elderly people. CMAJ 2004;171:897-904.
    • (2004) CMAJ , vol.171 , pp. 897-904
    • Garcia, A.1    Zanibbi, K.2
  • 10
    • 1342310863 scopus 로고    scopus 로고
    • Vitamin B12 status in the elderly as judged by available biochemical markers
    • Obeid R, Schorr H, Eckert R, Herrmann W. Vitamin B12 status in the elderly as judged by available biochemical markers. Clin Chem 2004;50:238-41.
    • (2004) Clin Chem , vol.50 , pp. 238-241
    • Obeid, R.1    Schorr, H.2    Eckert, R.3    Herrmann, W.4
  • 11
    • 0030881762 scopus 로고    scopus 로고
    • Vitamin B-12 deficiency in the elderly: Current dilemmas
    • Stabler SP, Lindenbaum J, Allen RH. Vitamin B-12 deficiency in the elderly: current dilemmas. Am J Clin Nutr 1997;66:741-9.
    • (1997) Am J Clin Nutr , vol.66 , pp. 741-749
    • Stabler, S.P.1    Lindenbaum, J.2    Allen, R.H.3
  • 12
    • 0034804914 scopus 로고    scopus 로고
    • Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly
    • Hultberg B, Isaksson A, Nilsson K, Gustafson L. Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly. Int J Geriatr Psychiatry 2001;16:873-8.
    • (2001) Int J Geriatr Psychiatry , vol.16 , pp. 873-878
    • Hultberg, B.1    Isaksson, A.2    Nilsson, K.3    Gustafson, L.4
  • 13
    • 28544447509 scopus 로고    scopus 로고
    • Plasma total homocysteine and memory in the elderly: The Hordaland Homocysteine Study
    • Nurk E, Refsum H, Tell GS, Engedal K, Vollset SE, Ueland PM, et al. Plasma total homocysteine and memory in the elderly: the Hordaland Homocysteine Study. Ann Neurol 2005;58:847-57.
    • (2005) Ann Neurol , vol.58 , pp. 847-857
    • Nurk, E.1    Refsum, H.2    Tell, G.S.3    Engedal, K.4    Vollset, S.E.5    Ueland, P.M.6
  • 14
    • 33646356980 scopus 로고    scopus 로고
    • Homocysteine and cognitive impairment: A case series in a General Practice setting
    • McCaddon A. Homocysteine and cognitive impairment: a case series in a General Practice setting. Nutr J 2006;5:6.
    • (2006) Nutr J , vol.5 , pp. 6
    • McCaddon, A.1
  • 16
    • 0038009864 scopus 로고    scopus 로고
    • Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia
    • Clarke R, Harrison G, Richards S. Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia. J Intern Med 2003;254:67-75.
    • (2003) J Intern Med , vol.254 , pp. 67-75
    • Clarke, R.1    Harrison, G.2    Richards, S.3
  • 17
    • 11144278243 scopus 로고    scopus 로고
    • Response of homocysteine, cystathionine, and methylmalonic acid to vitamin treatment in dialysis patients
    • Obeid R, Kuhlmann MK, Kohler H, Herrmann W. Response of homocysteine, cystathionine, and methylmalonic acid to vitamin treatment in dialysis patients. Clin Chem 2005;51:196-201.
    • (2005) Clin Chem , vol.51 , pp. 196-201
    • Obeid, R.1    Kuhlmann, M.K.2    Kohler, H.3    Herrmann, W.4
  • 18
    • 23044449221 scopus 로고    scopus 로고
    • Stable-isotope dilution liquid chromatography-electrospray injection tandem mass spectrometry method for fast, selective measurement of S-adenosylmethionine and S-adenosylhomocysteine in plasma
    • Gellekink H, van Oppenraaij-Emmerzaal D, van Rooij A, Struys EA, den Heijer M, Blom HJ. Stable-isotope dilution liquid chromatography-electrospray injection tandem mass spectrometry method for fast, selective measurement of S-adenosylmethionine and S-adenosylhomocysteine in plasma. Clin Chem 2005;51:1487-92.
    • (2005) Clin Chem , vol.51 , pp. 1487-1492
    • Gellekink, H.1    van Oppenraaij-Emmerzaal, D.2    van Rooij, A.3    Struys, E.A.4    den Heijer, M.5    Blom, H.J.6
  • 20
    • 0025945945 scopus 로고
    • Cerebrospinal fluid methylmalonic acid levels in normal subjects and patients with cobalamin deficiency
    • Stabler SP, Allen RH, Barrett RE, Savage DG, Lindenbaum J. Cerebrospinal fluid methylmalonic acid levels in normal subjects and patients with cobalamin deficiency. Neurology 1991;41:1627-32.
    • (1991) Neurology , vol.41 , pp. 1627-1632
    • Stabler, S.P.1    Allen, R.H.2    Barrett, R.E.3    Savage, D.G.4    Lindenbaum, J.5
  • 21
    • 0029799427 scopus 로고    scopus 로고
    • Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease
    • Morrison LD, Smith DD, Kish SJ. Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease. J Neurochem 1996;67:1328-31.
    • (1996) J Neurochem , vol.67 , pp. 1328-1331
    • Morrison, L.D.1    Smith, D.D.2    Kish, S.J.3
  • 22
    • 0025606597 scopus 로고
    • Cerebrospinal fluid S-adenosylmethionine in depression and dementia: Effects of treatment with parenteral and oral S-adenosylmethionine
    • Bottiglieri T, Godfrey P, Flynn T, Carney MW, Toone BK, Reynolds EH. Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine. J Neurol Neurosurg Psychiatry 1990;53:1096-8.
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , pp. 1096-1098
    • Bottiglieri, T.1    Godfrey, P.2    Flynn, T.3    Carney, M.W.4    Toone, B.K.5    Reynolds, E.H.6
  • 23
    • 0037645942 scopus 로고    scopus 로고
    • Increased plasma homocysteine levels without signs of vitamin B12 deficiency in patients with multiple sclerosis assessed by blood and cerebrospinal fluid homocysteine and methylmalonic acid
    • Vrethem M, Mattsson E, Hebelka H, Leerbeck K, Osterberg A, Landtblom AM, et al. Increased plasma homocysteine levels without signs of vitamin B12 deficiency in patients with multiple sclerosis assessed by blood and cerebrospinal fluid homocysteine and methylmalonic acid. Mult Scler 2003;9:239-45.
    • (2003) Mult Scler , vol.9 , pp. 239-245
    • Vrethem, M.1    Mattsson, E.2    Hebelka, H.3    Leerbeck, K.4    Osterberg, A.5    Landtblom, A.M.6
  • 24
    • 0030825848 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma total homocysteine and related metabolites in children with cystathionine β-synthase deficiency: The effect of treatment
    • Surtees R, Bowron A, Leonard J. Cerebrospinal fluid and plasma total homocysteine and related metabolites in children with cystathionine β-synthase deficiency: the effect of treatment. Pediatr Res 1997;42:577-82.
    • (1997) Pediatr Res , vol.42 , pp. 577-582
    • Surtees, R.1    Bowron, A.2    Leonard, J.3
  • 26
    • 0004499350 scopus 로고
    • Cerebrospinal fluid folate (CFA) and the blood brain barrier
    • Alperin JB, Haggard ME. Cerebrospinal fluid folate (CFA) and the blood brain barrier. Clin Res 1970;18:40.
    • (1970) Clin Res , vol.18 , pp. 40
    • Alperin, J.B.1    Haggard, M.E.2
  • 27
    • 0037157563 scopus 로고    scopus 로고
    • Folic acid, ageing, depression, and dementia
    • Reynolds EH. Folic acid, ageing, depression, and dementia. BMJ 2002;324:1512-5.
    • (2002) BMJ , vol.324 , pp. 1512-1515
    • Reynolds, E.H.1
  • 28
    • 0018757898 scopus 로고
    • Folate deficiency and decreased brain 5-hydroxytryptamine synthesis in man and rat
    • Botez MI, Young SN, Bachevalier J, Gauthier S. Folate deficiency and decreased brain 5-hydroxytryptamine synthesis in man and rat. Nature 1979;278:182-3.
    • (1979) Nature , vol.278 , pp. 182-183
    • Botez, M.I.1    Young, S.N.2    Bachevalier, J.3    Gauthier, S.4
  • 29
    • 2942616544 scopus 로고    scopus 로고
    • Effects of intraventricular methotrexate on folate, adenosine, and homocysteine metabolism in cerebrospinal fluid
    • Quinn CT, Griener JC, Bottiglieri T, Arning E, Winick NJ. Effects of intraventricular methotrexate on folate, adenosine, and homocysteine metabolism in cerebrospinal fluid. J Pediatr Hematol Oncol 2004;26:386-8.
    • (2004) J Pediatr Hematol Oncol , vol.26 , pp. 386-388
    • Quinn, C.T.1    Griener, J.C.2    Bottiglieri, T.3    Arning, E.4    Winick, N.J.5
  • 30
    • 27444437550 scopus 로고    scopus 로고
    • Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: Relation with age and Alzheimer's disease
    • Serot JM, Barbe F, Arning E, Bottiglieri T, Franck P, Montagne P, et al. Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease. J Neurol Neurosurg Psychiatry 2005;76:1585-7.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 1585-1587
    • Serot, J.M.1    Barbe, F.2    Arning, E.3    Bottiglieri, T.4    Franck, P.5    Montagne, P.6
  • 32
    • 0019366754 scopus 로고
    • Cobalamin binding and uptake in vitro in the human central nervous system
    • Lazar GS, Carmel R. Cobalamin binding and uptake in vitro in the human central nervous system. J Lab Clin Med 1981;97:123-33.
    • (1981) J Lab Clin Med , vol.97 , pp. 123-133
    • Lazar, G.S.1    Carmel, R.2
  • 33
    • 0028344335 scopus 로고
    • Synthesis and secretion of transcobalamin II by cultured astrocytes derived from human brain tissue
    • Begley JA, Colligan PD, Chu RC. Synthesis and secretion of transcobalamin II by cultured astrocytes derived from human brain tissue. J Neurol Sci 1994;122:57-60.
    • (1994) J Neurol Sci , vol.122 , pp. 57-60
    • Begley, J.A.1    Colligan, P.D.2    Chu, R.C.3
  • 34
    • 0025093135 scopus 로고
    • Vitamin B12 and folate concentrations in serum and cerebrospinal fluid of neurological patients with special reference to multiple sclerosis and dementia
    • Nijst TQ, Wevers RA, Schoonderwaldt HC, Hommes OR, de Haan AF. Vitamin B12 and folate concentrations in serum and cerebrospinal fluid of neurological patients with special reference to multiple sclerosis and dementia. J Neurol Neurosurg Psychiatry 1990;53:951-4.
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , pp. 951-954
    • Nijst, T.Q.1    Wevers, R.A.2    Schoonderwaldt, H.C.3    Hommes, O.R.4    de Haan, A.F.5
  • 35
    • 0014976405 scopus 로고
    • An isotopic measurement of vitamin B12 in cerebrospinal fluid
    • Frenkel EP, McCall MS, White JD. An isotopic measurement of vitamin B12 in cerebrospinal fluid. Am J Clin Pathol 1971;55:58-64.
    • (1971) Am J Clin Pathol , vol.55 , pp. 58-64
    • Frenkel, E.P.1    McCall, M.S.2    White, J.D.3
  • 36
    • 31544458134 scopus 로고    scopus 로고
    • Branched-chain amino acids: Enzyme and substrate regulation
    • Brosnan JT, Brosnan ME. Branched-chain amino acids: enzyme and substrate regulation. J Nutr 2006;136(Suppl):207S-11S.
    • (2006) J Nutr , vol.136 , Issue.SUPPL.
    • Brosnan, J.T.1    Brosnan, M.E.2
  • 37
    • 0035960650 scopus 로고    scopus 로고
    • The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type
    • Silverberg GD, Heit G, Huhn S, Jaffe RA, Chang SD, Bronte-Stewart H, et al. The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type. Neurology 2001;57:1763-6.
    • (2001) Neurology , vol.57 , pp. 1763-1766
    • Silverberg, G.D.1    Heit, G.2    Huhn, S.3    Jaffe, R.A.4    Chang, S.D.5    Bronte-Stewart, H.6
  • 38
    • 0026551962 scopus 로고
    • Correlation of the ratio of S-adenosyl-L-methionine to S-adenosyl-L-homocysteine in the brain and cerebrospinal fluid of the pig: Implications for the determination of this methylation ratio in human brain
    • Weir DG, Molloy AM, Keating JN, Young PB, Kennedy S, Kennedy DG, et al. Correlation of the ratio of S-adenosyl-L-methionine to S-adenosyl-L-homocysteine in the brain and cerebrospinal fluid of the pig: implications for the determination of this methylation ratio in human brain. Clin Sci (Lond) 1992;82:93-7.
    • (1992) Clin Sci (Lond) , vol.82 , pp. 93-97
    • Weir, D.G.1    Molloy, A.M.2    Keating, J.N.3    Young, P.B.4    Kennedy, S.5    Kennedy, D.G.6
  • 39
    • 0742269630 scopus 로고    scopus 로고
    • Quantification of serum and urinary S-adenosylmethionine and S-adenosylhomocysteine by stable-isotope-dilution liquid chromatography-mass spectrometry
    • Stabler SP, Allen RH. Quantification of serum and urinary S-adenosylmethionine and S-adenosylhomocysteine by stable-isotope-dilution liquid chromatography-mass spectrometry. Clin Chem 2004;50:365-72.
    • (2004) Clin Chem , vol.50 , pp. 365-372
    • Stabler, S.P.1    Allen, R.H.2
  • 40
    • 12144286157 scopus 로고    scopus 로고
    • S-adenosylhomocysteine hydrolase deficiency in a human: A genetic disorder of methionine metabolism
    • Baric I, Fumic K, Glenn B, Cuk M, Schulze A, Finkelstein JD, et al. S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism. Proc Natl Acad Sci U S A 2004;101:4234-9.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4234-4239
    • Baric, I.1    Fumic, K.2    Glenn, B.3    Cuk, M.4    Schulze, A.5    Finkelstein, J.D.6


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