Ca2+ sparks activate K+ and Cl- channels, resulting in spontaneous transient currents in guinea-pig tracheal myocytes

Journal of Physiology

Volumn 513, Issue 3, 1998, Pages 711-718

  ZhuGe, Ronghua ^a   Sims, Stephen M ^b   Tuft, Richard A ^a   Fogarty, Kevin E ^a   Walsh Jr , John V ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CHLORIDE CHANNEL; POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; BRADYKININ;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOSOL; DEPOLARIZATION; GUINEA PIG; IMAGING SYSTEM; MEMBRANE CURRENT; MUSCLE FIBER MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; TRACHEA MUSCLE; IMAGE ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR IMAGING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SPONTANEOUS TRANSIENT OUTWARD CURRENT; ALGORITHM; ANIMAL; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; CYTOLOGY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; IMAGE PROCESSING; IN VITRO STUDY; METABOLISM; PATCH CLAMP; PHYSIOLOGY; TIME; TRACHEA;

ALGORITHMS; ANIMALS; BRADYKININ; CALCIUM SIGNALING; CHLORIDE CHANNELS; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; GUINEA PIGS; IMAGE PROCESSING, COMPUTER-ASSISTED; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; TIME FACTORS; TRACHEA;

EID: 0032535422     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.711ba.x     Document Type: Article

References (29)

1. BERRIDGE, M. J. (1997). Elementary and global aspects of calcium signalling. Journal of Physiology 499, 291-306.
2. BOLTON, T. B. & IMAIZUMI, Y. (1996). Spontaneous transient outward currents in smooth muscle cells. Cell Calcium 20, 141-152.
3. BROWN, D. A., CONSTANTI, A. & ADAMS, P. R. (1983). Ca-activated potassium current in vertebrate sympathetic neurones. Cell Calcium 4, 407-420.
4. CARL, A., LEE, H. K. & SANDERS, K. M. (1996). Regulation of ion channels in smooth muscles by calcium. American Journal of Physiology 211, C9-34.
5. CHENG, H., LEDERER, W. J. & CANNELL, M. B. (1993). Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262, 740-744.
6. GORDIENKO, D. V, BOLTON, T. B. & CANNELL, M. B. (1998). Variability in spontaneous subcellular calcium release in guinea-pig ileum smooth muscle cells. Journal of Physiology 507, 707-720.
7. HASHITANI, H., VAN HELDEN, D. F. & SUZUKI, H. (1996). Properties of spontaneous depolarization in circular smooth muscle cells of rabbit urethra. British Journal of Pharmacology 118, 1627-1632.
8. 2+ storage sites in guinea-pig tracheal smooth muscle cells. European Journal of Pharmacology 282, 219-228.
9. - currents in single smooth muscle cells of guinea-pig trachea. European Journal of Pharmacology 306, 227-236.
10. + (BK) channels in rat hippocampal neurones produced by pore block from an associated particle. Journal of Physiology 508, 721-734.
11. HOGG, R. C., WANG, Q. & LARGE, W. A. (1993). Time course of spontaneous calcium-activated chloride currents in smooth muscle cells from the rabbit portal vein. Journal of Physiology 464, 15-31.
12. HOGG, R. C., WANG, Q. & LARGE, W. A. (1994). Action of niflumic acid on evoked and spontaneous calcium-activated chloride and potassium currents in smooth muscle cells from rabbit portal vein. British Journal of Pharmacology 112, 977-984.
13. JANSSEN, L. J. & SIMS, S. M. (1992). Acetylcholine activates non-selective cation and chloride conductance in canine and guinea-pig tracheal myocytes. Journal of Physiology 453, 197-218.
14. JANSSEN, L. J. & SIMS, S. M. (1994). Spontaneous transient inward currents and rhythmicity in canine and guinea-pig tracheal smooth muscle cells. Pflügers Archiv 427, 473-480.
15. KIRBER, M. T., ETTER, E. F., SINGER, J. J., FAY, F. S. & WALSH J. V. JR (1996). Sparks and STOCs in esophageal smooth muscle cells. Digestive Diseases and Sciences 41, 1893.
16. - conductance in smooth muscle. American Journal of Physiology 271, C435-454.
17. 2+-dependent ion channels in single myocytes from rat portal vein. Cell Calcium 20, 153-160.
18. 2+ indicators in smooth muscle cells. Biophysical Journal 75, 1774-1782.
19. NELSON, M. T., CHENG, H., RUBART, M., SANTANA, L. F., BONEV, A. D., KNOT, H. J. & LEDERER, W. J. (1995). Relaxation of arterial smooth muscle by calcium sparks. Science 270, 633-637.
20. NELSON, M. T., CONWAY, M. A., KNOT, H. J. & BRAYDEN, J. E. (1997). Chloride channel blockers inhibit myogenic tone in rat cerebral arteries. Journal of Physiology 502, 259-264.
21. PACAUD, P., LOIRAND, G., GREGOIRE, G., MIRONNEAU, C. & MIRONNEAU, J. (1992). Calcium-dependence of the calcium-activated chloride current in smooth muscle cells of rat portal vein. Pflügers Archiv 421, 125-130.
22. PARKER, I. & YAO, Y. (1991). Regenerative release of calcium from functionally discrete subcellular stores by inositol trisphosphate. Proceedings of the Royal Society B 246, 269-274.
23. 2+-independent long shut intervals in BK channels from rat muscle. Journal of Physiology 493, 673-689.
24. SIMS, S. M., JIAO, Y. & ZHENG, Z. G. (1996). Intracellular calcium stores in isolated tracheal smooth muscle cells. American Journal of Physiology 271, L300-309.
25. TSUGORKA, A., RÍOS, E. & BLATTER, L. A. (1995). Imaging elementary events of calcium release in skeletal muscle cells. Science 269, 1723-1726.
26. WALSH, J. V. JR & SINGER, J. J. (1980). Calcium action potential in single freshly isolated smooth muscle cells. American Journal of Physiology 239, C162-174.
27. WANG, Q., HOGG, R. C. & LARGE, W. A. (1992). Properties of spontaneous inward currents recorded in smooth muscle cells isolated from the rabbit portal vein. Journal of Physiology 451, 525-537.
28. YUAN, X. J. (1997). Role of calcium-activated chloride current in regulating pulmonary vasomotor tone. American Journal of Physiology 272, L959-968.
29. 2+ sparks and STOCs in smooth muscle cells. Biophysical Journal 74, 272.