Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors

Cancer Biology and Therapy

Volumn 6, Issue 5, 2007, Pages 661-667

  Yuza, Yuki ^a,b   Glatt, Karen A ^a   Jiang, Jingrui ^a,c   Greulich, Heidi ^a,c,d   Minami, Yuko ^a,c   Woo, Michele S ^a,c   Shimamura, Takeshi ^a,c   Shapiro, Geoffrey ^a,c   Lee, Jeffrey C ^a,d   Ji, Hongbin ^a   Feng, Whei ^a,c,d   Chen, Tzu Hsiu ^a,c,d   Yanagisawa, Haruhiko ^b   Wong, Kwok Kin ^a,c   Meyerson, Matthew ^a,d,e  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Ba F3 cells; EGFR inhibitors; EGFR mutation; Lung cancer; Pharmacogenomics

Indexed keywords

ERLOTINIB; PROTEIN TYROSINE KINASE INHIBITOR;

ARTICLE; AUTOPHOSPHORYLATION; CELL TRANSFORMATION; DRUG MECHANISM; EXON; GENE DELETION; HUMAN; IN VITRO STUDY; LUNG NON SMALL CELL CANCER; ONCOGENE; SOMATIC MUTATION;

EID: 33847371736     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.6.5.4003     Document Type: Article

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