메뉴 건너뛰기




Volumn 49, Issue 3, 2007, Pages 462-470

Monitoring Antitumor Efficacy of Rapamycin in Kaposi Sarcoma

Author keywords

AKT; Kaposi sarcoma; P70 S6 kinase; rapamycin sensitivity; surrogate molecular markers

Indexed keywords

CYCLOSPORIN A; MAMMALIAN TARGET OF RAPAMYCIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE;

EID: 33847314632     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2006.11.037     Document Type: Article
Times cited : (28)

References (45)
  • 1
    • 24644523670 scopus 로고    scopus 로고
    • Cancer incidence after immunosuppressive treatment following kidney transplantation
    • Andres A. Cancer incidence after immunosuppressive treatment following kidney transplantation. Crit Rev Oncol Hematol 56 (2005) 71-85
    • (2005) Crit Rev Oncol Hematol , vol.56 , pp. 71-85
    • Andres, A.1
  • 2
    • 0032235027 scopus 로고    scopus 로고
    • Occurrence of cancers in immunosuppressed organ transplant recipients
    • Penn I. Occurrence of cancers in immunosuppressed organ transplant recipients. Clin Transplant 1 (1998) 147-158
    • (1998) Clin Transplant , vol.1 , pp. 147-158
    • Penn, I.1
  • 4
    • 33645458234 scopus 로고    scopus 로고
    • Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation
    • Campistol J.M., Eris J., Oberbauer R., et al. Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation. J Am Soc Nephrol 17 (2006) 581-589
    • (2006) J Am Soc Nephrol , vol.17 , pp. 581-589
    • Campistol, J.M.1    Eris, J.2    Oberbauer, R.3
  • 5
    • 24644445998 scopus 로고    scopus 로고
    • Rapamycin: An anti-cancer immunosuppressant?
    • Law B.K. Rapamycin: An anti-cancer immunosuppressant?. Crit Rev Oncol Hematol 56 (2005) 47-60
    • (2005) Crit Rev Oncol Hematol , vol.56 , pp. 47-60
    • Law, B.K.1
  • 6
    • 24044551995 scopus 로고    scopus 로고
    • PI3K/Akt/mTOR pathway as a target for cancer therapy
    • Morgensztern D., and McLeod H.L. PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 16 (2005) 797-803
    • (2005) Anticancer Drugs , vol.16 , pp. 797-803
    • Morgensztern, D.1    McLeod, H.L.2
  • 7
    • 23144467910 scopus 로고    scopus 로고
    • An expanding role for mTOR in cancer
    • Guertin D.A., and Sabatini D.M. An expanding role for mTOR in cancer. Trends Mol Med 11 (2005) 353-361
    • (2005) Trends Mol Med , vol.11 , pp. 353-361
    • Guertin, D.A.1    Sabatini, D.M.2
  • 8
    • 20144367584 scopus 로고    scopus 로고
    • Sirolimus for Kaposi's sarcoma in renal-transplant recipients
    • Stallone G., Schena A., Infante B., et al. Sirolimus for Kaposi's sarcoma in renal-transplant recipients. N Engl J Med 352 (2005) 1317-1323
    • (2005) N Engl J Med , vol.352 , pp. 1317-1323
    • Stallone, G.1    Schena, A.2    Infante, B.3
  • 9
    • 13844273087 scopus 로고    scopus 로고
    • PI3K-Akt pathway: Its functions and alterations in human cancer
    • Osaki M., Oshimura M., and Ito H. PI3K-Akt pathway: Its functions and alterations in human cancer. Apoptosis 9 (2004) 667-676
    • (2004) Apoptosis , vol.9 , pp. 667-676
    • Osaki, M.1    Oshimura, M.2    Ito, H.3
  • 11
    • 27844515097 scopus 로고    scopus 로고
    • The Akt of translational control
    • Ruggero D., and Sonenberg N. The Akt of translational control. Oncogene 24 (2005) 7426-7434
    • (2005) Oncogene , vol.24 , pp. 7426-7434
    • Ruggero, D.1    Sonenberg, N.2
  • 13
    • 0142213135 scopus 로고    scopus 로고
    • Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/KDR
    • Bais C., Van Geelen A., Eroles P., et al. Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/KDR. Cancer Cell 3 (2003) 131-143
    • (2003) Cancer Cell , vol.3 , pp. 131-143
    • Bais, C.1    Van Geelen, A.2    Eroles, P.3
  • 14
    • 1842687489 scopus 로고    scopus 로고
    • Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor
    • Sodhi A., Montaner S., Patel V., et al. Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor. Proc Natl Acad Sci U S A 101 (2004) 4821-4826
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4821-4826
    • Sodhi, A.1    Montaner, S.2    Patel, V.3
  • 15
    • 1042267229 scopus 로고    scopus 로고
    • Determinants of rapamycin sensitivity in breast cancer cells
    • Noh W.C., Mondesire W.H., Peng J., et al. Determinants of rapamycin sensitivity in breast cancer cells. Clin Cancer Res 10 (2004) 1013-1023
    • (2004) Clin Cancer Res , vol.10 , pp. 1013-1023
    • Noh, W.C.1    Mondesire, W.H.2    Peng, J.3
  • 16
    • 0041662261 scopus 로고    scopus 로고
    • Pharmacodynamic evaluation of CCI-779, an inhibitor of mTOR, in cancer patients
    • Peralba J.M., DeGraffenried L., Friedrichs W., et al. Pharmacodynamic evaluation of CCI-779, an inhibitor of mTOR, in cancer patients. Clin Cancer Res 9 (2003) 2887-2892
    • (2003) Clin Cancer Res , vol.9 , pp. 2887-2892
    • Peralba, J.M.1    DeGraffenried, L.2    Friedrichs, W.3
  • 17
    • 9144233506 scopus 로고    scopus 로고
    • Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells
    • Boulay A., Zumstein-Mecker S., Stephan C., et al. Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells. Cancer Res 64 (2004) 252-261
    • (2004) Cancer Res , vol.64 , pp. 252-261
    • Boulay, A.1    Zumstein-Mecker, S.2    Stephan, C.3
  • 18
    • 32844474879 scopus 로고    scopus 로고
    • Glucose metabolism in renal transplant recipients. The effect of calcineurin inhibitor withdrawal and conversion to sirolimus
    • Teutonico A., Schena F.P., and Di Paolo S. Glucose metabolism in renal transplant recipients. The effect of calcineurin inhibitor withdrawal and conversion to sirolimus. J Am Soc Nephrol 16 (2005) 3128-3135
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3128-3135
    • Teutonico, A.1    Schena, F.P.2    Di Paolo, S.3
  • 19
    • 0037099573 scopus 로고    scopus 로고
    • Assessment of sirolimus concentrations in whole blood by high-performance liquid chromatography with ultraviolet detection
    • Cattaneo D., Perico N., and Gaspari F. Assessment of sirolimus concentrations in whole blood by high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci 774 (2002) 187-194
    • (2002) J Chromatogr B Analyt Technol Biomed Life Sci , vol.774 , pp. 187-194
    • Cattaneo, D.1    Perico, N.2    Gaspari, F.3
  • 20
    • 33746488875 scopus 로고    scopus 로고
    • Chronic inhibition of mTOR signaling down-regulates IRS-1/2 and AKT activation: A crossroad between cancer and diabetes?
    • Di Paolo S., Teutonico A., Leogrande D., Capobianco C., and Schena F.P. Chronic inhibition of mTOR signaling down-regulates IRS-1/2 and AKT activation: A crossroad between cancer and diabetes?. J Am Soc Nephrol 17 (2006) 2236-2244
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2236-2244
    • Di Paolo, S.1    Teutonico, A.2    Leogrande, D.3    Capobianco, C.4    Schena, F.P.5
  • 22
    • 0034614893 scopus 로고    scopus 로고
    • Viral G protein-coupled receptor and Kaposi's sarcoma: A model of paracrine neoplasia?
    • Cesarman E., Mesri E.A., and Gershengorn M.C. Viral G protein-coupled receptor and Kaposi's sarcoma: A model of paracrine neoplasia?. J Exp Med 191 (2000) 417-422
    • (2000) J Exp Med , vol.191 , pp. 417-422
    • Cesarman, E.1    Mesri, E.A.2    Gershengorn, M.C.3
  • 23
    • 0034827715 scopus 로고    scopus 로고
    • Serum concentrations of fibroblast growth factor 2 are increased in HIV type 1-infected patients and inversely related to survival probability
    • Ascherl G., Sgadari C., Bugarini R., et al. Serum concentrations of fibroblast growth factor 2 are increased in HIV type 1-infected patients and inversely related to survival probability. AIDS Res Hum Retroviruses 17 (2001) 1035-1039
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 1035-1039
    • Ascherl, G.1    Sgadari, C.2    Bugarini, R.3
  • 24
    • 3042738138 scopus 로고    scopus 로고
    • Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma
    • Wang H.W., Trotter M.W., Lagos D., et al. Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. Nat Genet 36 (2004) 687-693
    • (2004) Nat Genet , vol.36 , pp. 687-693
    • Wang, H.W.1    Trotter, M.W.2    Lagos, D.3
  • 25
    • 19344370532 scopus 로고    scopus 로고
    • B-Raf-dependent expression of vascular endothelial growth factor-A in Kaposi sarcoma-associated herpesvirus-infected human B cells
    • Akula S.M., Ford P.W., Whitman A.G., et al. B-Raf-dependent expression of vascular endothelial growth factor-A in Kaposi sarcoma-associated herpesvirus-infected human B cells. Blood 105 (2005) 4516-4522
    • (2005) Blood , vol.105 , pp. 4516-4522
    • Akula, S.M.1    Ford, P.W.2    Whitman, A.G.3
  • 26
    • 0036229879 scopus 로고    scopus 로고
    • Cytokines regulate alpha(1)-adrenergic receptor mRNA expression in human monocytic cells and endothelial cells
    • Heijnen C.J., Rouppe van der Voort C., van de Pol M., and Kavelaars A. Cytokines regulate alpha(1)-adrenergic receptor mRNA expression in human monocytic cells and endothelial cells. J Neuroimmunol 125 (2002) 66-72
    • (2002) J Neuroimmunol , vol.125 , pp. 66-72
    • Heijnen, C.J.1    Rouppe van der Voort, C.2    van de Pol, M.3    Kavelaars, A.4
  • 27
    • 0034681369 scopus 로고    scopus 로고
    • Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts
    • Ballou L.M., Cross M.E., Huang S., McReynolds E.M., Zhang B.X., and Lin R.Z. Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts. J Biol Chem 275 (2000) 4803-4809
    • (2000) J Biol Chem , vol.275 , pp. 4803-4809
    • Ballou, L.M.1    Cross, M.E.2    Huang, S.3    McReynolds, E.M.4    Zhang, B.X.5    Lin, R.Z.6
  • 28
    • 27144514347 scopus 로고    scopus 로고
    • Beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA
    • Chang M., Brown H.J., Collado-Hidalgo A., et al. Beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA. J Virol 79 (2005) 13538-13547
    • (2005) J Virol , vol.79 , pp. 13538-13547
    • Chang, M.1    Brown, H.J.2    Collado-Hidalgo, A.3
  • 29
    • 11844304072 scopus 로고    scopus 로고
    • Restraining PI3K: mTOR signalling goes back to the membrane
    • Harrington L.S., Findlay G.M., and Lamb R.F. Restraining PI3K: mTOR signalling goes back to the membrane. Trends Biochem Sci 30 (2005) 35-42
    • (2005) Trends Biochem Sci , vol.30 , pp. 35-42
    • Harrington, L.S.1    Findlay, G.M.2    Lamb, R.F.3
  • 30
    • 2942556904 scopus 로고    scopus 로고
    • IL-1beta suppresses prolonged Akt activation and expression of E2F-1 and cyclin A in breast cancer cells
    • Shen W.H., Jackson S.T., Broussard S.R., et al. IL-1beta suppresses prolonged Akt activation and expression of E2F-1 and cyclin A in breast cancer cells. J Immunol 172 (2004) 7272-7281
    • (2004) J Immunol , vol.172 , pp. 7272-7281
    • Shen, W.H.1    Jackson, S.T.2    Broussard, S.R.3
  • 31
    • 32944457064 scopus 로고    scopus 로고
    • Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation
    • Awale S., Lu J., Kalauni S.K., et al. Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation. Cancer Res 66 (2006) 1751-1757
    • (2006) Cancer Res , vol.66 , pp. 1751-1757
    • Awale, S.1    Lu, J.2    Kalauni, S.K.3
  • 32
    • 17144427728 scopus 로고    scopus 로고
    • Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
    • Takeuchi H., Kondo Y., Fujiwara K., et al. Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Res 65 (2005) 3336-3346
    • (2005) Cancer Res , vol.65 , pp. 3336-3346
    • Takeuchi, H.1    Kondo, Y.2    Fujiwara, K.3
  • 33
    • 1642586272 scopus 로고    scopus 로고
    • Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
    • Wendel H.G., De Stanchina E., Fridman J.S., et al. Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 428 (2004) 332-337
    • (2004) Nature , vol.428 , pp. 332-337
    • Wendel, H.G.1    De Stanchina, E.2    Fridman, J.S.3
  • 34
    • 0346362997 scopus 로고    scopus 로고
    • Rapamycins: Mechanism of action and cellular resistance
    • Huang S., Bjornsti M.A., and Houghton P.J. Rapamycins: Mechanism of action and cellular resistance. Cancer Biol Ther 2 (2003) 222-232
    • (2003) Cancer Biol Ther , vol.2 , pp. 222-232
    • Huang, S.1    Bjornsti, M.A.2    Houghton, P.J.3
  • 35
    • 0037224547 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase/AKT1 pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells
    • Neri L.M., Borgatti P., Tazzari P.L., et al. The phosphoinositide 3-kinase/AKT1 pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells. Mol Cancer Res 1 (2003) 234-246
    • (2003) Mol Cancer Res , vol.1 , pp. 234-246
    • Neri, L.M.1    Borgatti, P.2    Tazzari, P.L.3
  • 36
    • 1842852634 scopus 로고    scopus 로고
    • Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors
    • Xu G., Zhang W., Bertram P., Zheng X.F., and McLeod H. Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors. Int J Oncol 24 (2004) 893-900
    • (2004) Int J Oncol , vol.24 , pp. 893-900
    • Xu, G.1    Zhang, W.2    Bertram, P.3    Zheng, X.F.4    McLeod, H.5
  • 37
    • 18144399578 scopus 로고    scopus 로고
    • mTOR-targeted therapy of cancer with rapamycin derivatives
    • Vignot S., Faivre S., Aguirre D., and Raymond E. mTOR-targeted therapy of cancer with rapamycin derivatives. Ann Oncol 16 (2005) 525-537
    • (2005) Ann Oncol , vol.16 , pp. 525-537
    • Vignot, S.1    Faivre, S.2    Aguirre, D.3    Raymond, E.4
  • 38
    • 1542398693 scopus 로고    scopus 로고
    • Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
    • Atkins M.B., Hidalgo M., Stadler W.M., et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J Clin Oncol 22 (2004) 909-918
    • (2004) J Clin Oncol , vol.22 , pp. 909-918
    • Atkins, M.B.1    Hidalgo, M.2    Stadler, W.M.3
  • 39
    • 0033515590 scopus 로고    scopus 로고
    • Suboptimal cross-linking of antigen receptor induces Syk-dependent activation of p70S6 kinase through protein kinase C and phosphoinositol 3-kinase
    • Li H.L., Davis W., and Pure E. Suboptimal cross-linking of antigen receptor induces Syk-dependent activation of p70S6 kinase through protein kinase C and phosphoinositol 3-kinase. J Biol Chem 274 (1999) 9812-9820
    • (1999) J Biol Chem , vol.274 , pp. 9812-9820
    • Li, H.L.1    Davis, W.2    Pure, E.3
  • 40
    • 0037295455 scopus 로고    scopus 로고
    • Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues
    • Miyakawa M., Tsushima T., Murakami H., Wakai K., Isozaki O., and Takano K. Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues. Endocr J 50 (2003) 77-83
    • (2003) Endocr J , vol.50 , pp. 77-83
    • Miyakawa, M.1    Tsushima, T.2    Murakami, H.3    Wakai, K.4    Isozaki, O.5    Takano, K.6
  • 41
    • 4444278397 scopus 로고    scopus 로고
    • Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway
    • Nathan C.A., Amirghahari N., Abreo F., et al. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway. Clin Cancer Res 10 (2004) 5820-5827
    • (2004) Clin Cancer Res , vol.10 , pp. 5820-5827
    • Nathan, C.A.1    Amirghahari, N.2    Abreo, F.3
  • 42
    • 2442534048 scopus 로고    scopus 로고
    • Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients
    • van der Hage J.A., van den Broek L.J., Legrand C., et al. Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients. Br J Cancer 90 (2004) 1543-1550
    • (2004) Br J Cancer , vol.90 , pp. 1543-1550
    • van der Hage, J.A.1    van den Broek, L.J.2    Legrand, C.3
  • 44
    • 19944430292 scopus 로고    scopus 로고
    • Immunohistochemical analysis of S6K1 and S6K2 expression in endometrial adenocarcinomas
    • Lyzogubov V.V., Lytvyn D.I., Dudchenko T.M., et al. Immunohistochemical analysis of S6K1 and S6K2 expression in endometrial adenocarcinomas. Exp Oncol 26 (2004) 287-293
    • (2004) Exp Oncol , vol.26 , pp. 287-293
    • Lyzogubov, V.V.1    Lytvyn, D.I.2    Dudchenko, T.M.3
  • 45
    • 27544505190 scopus 로고    scopus 로고
    • Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck
    • Amornphimoltham P., Patel V., Sodhi A., et al. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck. Cancer Res 65 (2005) 9953-9961
    • (2005) Cancer Res , vol.65 , pp. 9953-9961
    • Amornphimoltham, P.1    Patel, V.2    Sodhi, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.