Development and characterization of film forming polymeric solutions for skin drug delivery

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 65, Issue 1, 2007, Pages 111-121

  Zurdo Schroeder, Ines ^a,b   Franke, Patrick ^a   Schaefer, Ulrich F ^b   Lehr, Claus Michael ^b  

^a Intendis GmbH   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Film forming polymeric solution; Mechanical properties; Transepidermal water loss; Water vapor permeability

Indexed keywords

ACRYLIC ACID COPOLYMER; ACRYLIC ACID OCTYLACRYLAMIDE COPOLYMER; ALKENE; AVALURE; CHITOSAN; CITRIC ACID TRIETHYL ESTER; COPOLYMER; DERMACRYL; DOW CORNING; DYNAMX; EUDRAGIT; HYDROXYPROPYLCELLULOSE; OPPANOL; POLYISOBUTYLENE; POLYMER; POLYVINYL ALCOHOL; POLYVINYLPYRROLIDONE VINYL ACETATE COPOLYMER; POVIDONE; SILICON;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FEMALE; FILM; HUMAN; MALE; NORMAL HUMAN; PHYSICAL CHEMISTRY; SKIN ABRASION; SKIN WATER LOSS; TEMPERATURE SENSITIVITY; TENSILE STRENGTH; VISCOSITY; WATER VAPOR;

ADHESIVENESS; ADMINISTRATION, CUTANEOUS; ADULT; DRUG CARRIERS; FEMALE; HUMANS; HUMIDITY; MALE; PERMEABILITY; PLASTICIZERS; POLYMERS; SKIN; SKIN PHYSIOLOGY; SOLVENTS; TEMPERATURE; TENSILE STRENGTH; TIME FACTORS; VISCOSITY; VOLATILIZATION; WATER; WATER LOSS, INSENSIBLE;

EID: 33847306542     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.07.015     Document Type: Article

References (41)

1. Donkerwolcke M., Burny F., and Muster D. Tissues and bone adhesives - historical aspects. Biomaterials 19 (1998) 1461-1466
2. Hall L.T., and Bailes J.E. Using Dermabond for wound closure in lumbar and cervical neurosurgical procedures. Neurosurgery 56 (2005) 147-150
3. Ritterband D.C., Meskin S.W., Shapiro D.E., Kusmierczyk J., Seedor J.A., and Koplin R.S. Laboratory model of tissue adhesive (2-octyl cyanoacrylate) in sealing clear corneal cataract wounds. Am. J. Ophthalmol. 140 (2005) 1039-1043
4. Jeng D.K. A new, water-resistant, film-forming, 30-second, one-step application iodophor preoperative skin preparation. Am. J. Infect. Control 29 (2001) 370-376
5. Foroutan S.M., Ettehadi H.A., and Torabi H.R. Formulation and in vitro evaluation of silver sulfadiazine spray. Iran. J. Pharm. Res. 1 (2002) 47-49
6. Eaglstein W.H., Sullivan T.P., Giordano P.A., and Miskin B.M. A liquid adhesive bandage for the treatment of minor cuts and abrasions. Dermatol. Surg. 28 (2002) 263-267
7. Campbell K., Woodbury M.G., Whittle H., Labate T., and Hoskin A. A clinical evaluation of 3M No Sting Barrier Film. Ostomy Wound Manage. 46 (2000) 24-30
8. Misra A., Raghuvanshi R.S., Ganga S., Diwan M., Talwar G.P., and Singh O. Formulation of a transdermal system for biphasic delivery of testosterone. J. Control. Release 39 (1996) 1-7
9. Misra A., Pal R., Majumdar S.S., Talwar G.P., and Singh O. Biphasic testosterone delivery profile observed with two different transdermal formulations. Pharm. Res. 14 (1997) 1264-1268
10. An N.M., Kim D.D., Shin Y.H., and Lee C.H. Development of a novel soft hydrogel for the transdermal delivery of testosterone. Drug Dev. Ind. Pharm. 29 (2003) 99-105
11. Maffei P., Sforzini A., Lombardi Borgia S., Ronchi C., Festo N., and Ceschel G.C. Design and evaluation of a new transdermal formulation containing Estradiol. Pharm. Ind. 65 (2003) 1279-1282
12. Bryan H.A., and Alster T.S. The S-Caine Peel: a novel topical anestetic for cutaneous laser surgery. Dermatol. Surg. 28 (2002) 999-1003
13. American Society for Testing and Materials, D 882-02 Standard Test Method for Tensile Properties of Thin Plastic Sheeting, ASTM International, 100 Barr Harbor Drive, P.O. Box C700, West Conshohocken, USA, 2002.
14. Rindlav-Westling A., Stading M., Hermansson A.M., and Gatenholm P. Structure, mechanical and barrier properties of amylose and amylopectin films. Carbohydr. Polym. 36 (1998) 217-224
15. Repka M.A., and McGinity J.W. Physical-mechanical, moisture absorption and bioadhesive properties of hydroxypropylcellulose hot-melt extruded films. Biomaterials 21 (2000) 1509-1517
16. Liu J., and Williams R.O. Properties of heat-humidity cured cellulose acetate phthalate free films. Eur. J. Pharm. Sci. 17 (2002) 31-41
17. Rama Rao P., and Diwan P.V. Permeability studies of cellulose acetate free films for transdermal use: influence of plasticizers. Pharm. Acta Helv. 72 (1997) 47-51
18. Padula C., Colombo G., Nicoli S., Catellani P.L., Massimo G., and Santi P. Bioadhesive film for the transdermal delivery of lidocaine: in vitro and in vivo behavior. J. Control. Release 88 (2003) 277-285
19. Water-vapour Permeability, in: British Pharmacopoeia, 1993, Appendix XXJ.
20. OECD. Guidance document for the conduct of skin absorption studies, OECD series on testing and assessment, No. 28, 2004.
21. Tarvainen M., Sutinen R., Peltonen S., Tiihonen P., and Paronen P. Starch Acetate - a novel film-forming polymer for pharmaceutical coatings. J. Pharm. Sci. 91 (2002) 282-289
22. Patel M., Patel J.M., and Lemberger A.P. Water vapor permeation of selected cellulose ester films. J. Pharm. Sci. 53 (1964) 286-290
23. Pinnagoda J., Tupker R.A., and Serup J. Guidelines for transepidermal water loss (TEWL) measurement. Contact Dermatitis 22 (1990) 164-178
24. Treffel P., Muret P., Muret-D'Aniello P., Coumes-Marquet S., and Agache P. Effect of occlusion on in vitro percutaneous absorption of two compounds with different physicochemical properties. Skin Pharmacol. 5 (1992) 108-113
25. Qiao G.L., Chang S.K., and Riviere J.E. Effects of anatomical site and occlusion on the percutaneous absorption and residue pattern of 2, 6-(ring-14C)Parathion in vivo in pigs. Toxicol. Appl. Pharmacol. 122 (1993) 131-138
26. Bucks D.A., McMaster J.R., Maibach H.I., and Guy R.H. Bioavailability of topically administered steroids: a "mass balance" technique. J. Investig. Dermatol. 91 (1988) 29-33
27. Hotchkiss S.A., Miller J.M., and Caldwell J. Percutaneous absorption of benzyl acetate through rat skin in vitro. 2. Effect of vehicle and occlusion. Food Chem. Toxicol. 30 (1992) 145-153
28. Zhai H., and Maibach H. Effects on skin occlusion on percutaneous absorption: an overview. Skin Pharmacol. Appl. Skin Physiol. 14 (2001) 1-10
29. Matsumura H., Oka K., Umekage K., Akita H., Kawai J., Kitazawa Y., Suda S., Tsubota K., Ninomiya Y., Hirai H., et al. Effect of occlusion on human skin. Contact Dermatitis 33 (1995) 231-235
30. Grice K., Sattar H., Sharratt M., and Baker H. Skin temperature and transepidermal water loss. J. Investig. Dermatol. 57 (1971) 108-110
31. Grice K., Sattar H., and Baker H. The effect of ambient humidity on transepidermal water loss. J. Investig. Dermatol. 58 (1972) 343-346
32. Swarbrick J., Amann A.H., and Lindstrom R.E. Factors affecting water vapor transmission through free polymer films. J. Pharm. Sci. 61 (1972) 1645-1647
33. Sprockel O.L., Prapaitrakul W., and Shivanand P. Permeability of cellulose polymers: water vapour transmission rates. J. Pharm. Pharmacol. 42 (1990) 152-157
34. Casiraghi A., Minghetti P., Cilurzo F., Montanari L., and Naik A. Occlusive properties of monolayer patches: in vitro and in vivo evaluation. Pharm. Res. 19 (2002) 423-426
35. Pinnagoda J., Tupker R.A., Smit J.A., Coenraads P.J., and Nater J.P. The intra- and inter-individual variability and reliability of transepidermal water loss measurements. Contact Dermatitis 21 (1989) 255-259
36. Aulton M.E., and Abdul-Razzak M.H. The mechanical properties of hydroxypropylmethylcellulose films derived from aqueous systems, part I: the influence of plasticizers. Drug Dev. Ind. Pharm. 7 (1981) 649-668
37. Lin S.Y., Lee C.J., and Lin Y.Y. Drug-polymer interactions affecting the mechanical properties, adhesion strength and release kinetics of piroxicam-loaded Eudragit E films plasticized with different plasticizers. J. Control. Release 33 (1995) 375-381
38. Mint A., Hotchkiss S.A.M., and Caldwell J. Percutaneous absorption of diethyl phthalate through rat and human skin. Toxicol. In Vitro 8 (1994) 251-256
39. Boddé H.E., Van Aalten E.A.C., and Junginger H.E. Hydrogel patches for transdermal drug delivery; in-vivo water exchange and skin compatibility. J. Pharm. Pharmacol. 41 (1989) 152-155
40. Gutierrez-Rocca J.C., and McGinity J.W. Influence of aging on the physical-mechanical properties of acrylic resin films cast from aqueous dispersions and organic solutions. Drug Dev. Ind. Pharm. 19 (1993) 315-332
41. Stubberud L., Arwidsson H.G., Hjortsberg V., and Graffner C. Water-solid interactions. III. Effect of glass transitions temperature, Tg, and processing on tensile strength of compacts of lactose and lactose/polyvinyl pyrrolidone. Pharm. Dev. Technol. 1 (1996) 195-204