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Volumn 35, Issue 1, 2007, Pages 81-85

K-ras Mutations in Lung Tumors and Tumors from Other Organs are Consistent with a Common Mechanism of Ethylene Oxide Tumorigenesis in the B6C3F1 Mouse

Author keywords

carcinogen; ethylene oxide; Harderian gland; K ras; lung; mice; neoplasm; uterus

Indexed keywords

ETHYLENE OXIDE; K RAS PROTEIN;

EID: 33847277045     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230601063839     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 0030025982 scopus 로고    scopus 로고
    • In vivo and in vitro kinetics of ethylene oxide metabolism in rats and mice
    • Brown CD Wong BA Fennell TR In vivo and in vitro kinetics of ethylene oxide metabolism in rats and mice Toxicol Appl Pharmacol 1996 136 8 19
    • (1996) Toxicol Appl Pharmacol , vol.136 , pp. 8-19
    • Brown, C.D.1    Wong, B.A.2    Fennell, T.R.3
  • 2
    • 0026096577 scopus 로고
    • Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse
    • Devereux TR Anderson MW Belinsky SA Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse Carcinogenesis 1991 12 299 303
    • (1991) Carcinogenesis , vol.12 , pp. 299-303
    • Devereux, T.R.1    Anderson, M.W.2    Belinsky, S.A.3
  • 3
    • 0027314749 scopus 로고
    • Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride
    • Devereux TR Foley JF Maronpot RR Kari F Anderson MW Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride Carcinogenesis 1993 14 795 801
    • (1993) Carcinogenesis , vol.14 , pp. 795-801
    • Devereux, T.R.1    Foley, J.F.2    Maronpot, R.R.3    Kari, F.4    Anderson, M.W.5
  • 4
    • 0032035009 scopus 로고    scopus 로고
    • Oncogene and tumour suppressor gene expression changes in persons exposed to ethylene oxide
    • Ember I Kiss I Malovics I Oncogene and tumour suppressor gene expression changes in persons exposed to ethylene oxide Eur J Cancer Prev 1998 7 167 8
    • (1998) Eur J Cancer Prev , vol.7 , pp. 167-168
    • Ember, I.1    Kiss, I.2    Malovics, I.3
  • 5
    • 0028043929 scopus 로고
    • Activation of H-ras is prevalent in 1,3-butadiene-induced and spontaneously occurring murine Harderian gland tumors
    • Goodrow TL Nichols WW Storer RD Anderson MW Maronpot RR Activation of H-ras is prevalent in 1,3-butadiene-induced and spontaneously occurring murine Harderian gland tumors Carcinogenesis 1994 15 2665 7
    • (1994) Carcinogenesis , vol.15 , pp. 2665-2667
    • Goodrow, T.L.1    Nichols, W.W.2    Storer, R.D.3    Anderson, M.W.4    Maronpot, R.R.5
  • 6
    • 0034823814 scopus 로고    scopus 로고
    • High frequency of ras mutations in forestomach and lung tumors of B6C3F1 mice exposed to 1-amino-2,4-dibromoanthraquinone for 2 years
    • Hayashi S Hong HH Toyoda K Ton TV Devereux TR Maronpot RR Huff J Sills RC High frequency of ras mutations in forestomach and lung tumors of B6C3F1 mice exposed to 1-amino-2,4-dibromoanthraquinone for 2 years Toxicol Pathol 2001 29 422 9
    • (2001) Toxicol Pathol , vol.29 , pp. 422-429
    • Hayashi, S.1    Hong, H.H.2    Toyoda, K.3    Ton, T.V.4    Devereux, T.R.5    Maronpot, R.R.6    Huff, J.7    Sills, R.C.8
  • 7
    • 0028006345 scopus 로고
    • Glycolaldehyde causes DNA-protein crosslinks: a new aspect of ethylene oxide genotoxicity
    • Hengstler JG Fuchs J Gebhard S Oesch F Glycolaldehyde causes DNA-protein crosslinks: a new aspect of ethylene oxide genotoxicity Mutat Res 1994 304 229 34
    • (1994) Mutat Res , vol.304 , pp. 229-234
    • Hengstler, J.G.1    Fuchs, J.2    Gebhard, S.3    Oesch, F.4
  • 8
  • 9
    • 0028691804 scopus 로고
    • IARC working group on the evaluation of carcinogenic risks to humans: some industrial chemicals. Lyon, 15–22 February 1994
    • IARC IARC working group on the evaluation of carcinogenic risks to humans: some industrial chemicals. Lyon, 15–22 February 1994 IARC Monogr Eval Carcinog Risks Hum 1994 60 1 560
    • (1994) IARC Monogr Eval Carcinog Risks Hum , vol.60 , pp. 1-560
  • 10
    • 0029111612 scopus 로고
    • Role of point mutation of the K-ras gene in tumorigenesis of B6C3F1 mouse lung lesions induced by urethane
    • Kawano R Nishisaka T Takeshima Y Yonehara S Inai K Role of point mutation of the K-ras gene in tumorigenesis of B6C3F1 mouse lung lesions induced by urethane Jpn J Cancer Res 1995 86 802 10
    • (1995) Jpn J Cancer Res , vol.86 , pp. 802-810
    • Kawano, R.1    Nishisaka, T.2    Takeshima, Y.3    Yonehara, S.4    Inai, K.5
  • 11
    • 0026809854 scopus 로고
    • Cytogenetic study of persons occupationally exposed to ethylene oxide
    • Lerda D Rizzi R Cytogenetic study of persons occupationally exposed to ethylene oxide Mutat Res 1992 281 31 7
    • (1992) Mutat Res , vol.281 , pp. 31-37
    • Lerda, D.1    Rizzi, R.2
  • 12
    • 0026773508 scopus 로고
    • In vitro reaction of ethylene oxide with DNA and characterization of DNA adducts
    • Li F Segal A Solomon JJ In vitro reaction of ethylene oxide with DNA and characterization of DNA adducts Chem Biol Interact 1992 83 35 54
    • (1992) Chem Biol Interact , vol.83 , pp. 35-54
    • Li, F.1    Segal, A.2    Solomon, J.J.3
  • 13
    • 0035978608 scopus 로고    scopus 로고
    • Induction and persistence of micronuclei, sister-chromatid exchanges and chromosomal aberrations in splenocytes and bone-marrow cells of rats exposed to ethylene oxide
    • Lorenti Garcia C Darroudi F Tates AD Natarajan AT Induction and persistence of micronuclei, sister-chromatid exchanges and chromosomal aberrations in splenocytes and bone-marrow cells of rats exposed to ethylene oxide Mutat Res 2001 492 59 67
    • (2001) Mutat Res , vol.492 , pp. 59-67
    • Lorenti Garcia, C.1    Darroudi, F.2    Tates, A.D.3    Natarajan, A.T.4
  • 14
    • 21444458657 scopus 로고    scopus 로고
    • Involvement of the ras genes in female genital tract cancer
    • Mammas IN Zafiropoulos A Spandidos DA Involvement of the ras genes in female genital tract cancer Int J Oncol 2005 26 1241 55
    • (2005) Int J Oncol , vol.26 , pp. 1241-1255
    • Mammas, I.N.1    Zafiropoulos, A.2    Spandidos, D.A.3
  • 15
    • 0036965324 scopus 로고    scopus 로고
    • Carcinogenicity and mechanistic insights on the behavior of epoxides and epoxide-forming chemicals
    • Melnick RL Carcinogenicity and mechanistic insights on the behavior of epoxides and epoxide-forming chemicals Ann N Y Acad Sci 2002 982 177 89
    • (2002) Ann N Y Acad Sci , vol.982 , pp. 177-189
    • Melnick, R.L.1
  • 16
    • 0013887614 scopus 로고
    • Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules
    • Miller EC Miller JA Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules Pharmacol Rev 1966 18 805 38
    • (1966) Pharmacol Rev , vol.18 , pp. 805-838
    • Miller, E.C.1    Miller, J.A.2
  • 17
    • 0029075553 scopus 로고
    • Rare occurrence of p53 and ras gene mutations in preneoplastic and neoplastic mouse endometrial lesions induced by N-methyl-N-nitrosourea and 17 beta-estradiol
    • Murase T Niwa K Morishita S Itoh N Mori H Tanaka T Tamaya T Rare occurrence of p53 and ras gene mutations in preneoplastic and neoplastic mouse endometrial lesions induced by N-methyl-N-nitrosourea and 17 beta-estradiol Cancer Lett 1995 92 223 7
    • (1995) Cancer Lett , vol.92 , pp. 223-227
    • Murase, T.1    Niwa, K.2    Morishita, S.3    Itoh, N.4    Mori, H.5    Tanaka, T.6    Tamaya, T.7
  • 19
    • 0038032435 scopus 로고    scopus 로고
    • 11, Research Triangle Park, NC, U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program
    • NTP Report on Carcinogens 2004 11 Research Triangle Park, NC U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program
    • (2004) Report on Carcinogens
  • 20
    • 0025670013 scopus 로고
    • Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas
    • Nuzum EO Malkinson AM Beer DG Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas Mol Carcinog 1990 3 287 95
    • (1990) Mol Carcinog , vol.3 , pp. 287-295
    • Nuzum, E.O.1    Malkinson, A.M.2    Beer, D.G.3
  • 22
    • 2942583950 scopus 로고    scopus 로고
    • In vivo mutagenicity and mutation spectrum in the bone marrow and testes of B6C3F1 lacI transgenic mice following inhalation exposure to ethylene oxide
    • Recio L Donner M Abernethy D Pluta L Steen AM Wong BA James A Preston RJ In vivo mutagenicity and mutation spectrum in the bone marrow and testes of B6C3F1 lacI transgenic mice following inhalation exposure to ethylene oxide Mutagenesis 2004 19 215 22
    • (2004) Mutagenesis , vol.19 , pp. 215-222
    • Recio, L.1    Donner, M.2    Abernethy, D.3    Pluta, L.4    Steen, A.M.5    Wong, B.A.6    James, A.7    Preston, R.J.8
  • 23
    • 0031886443 scopus 로고    scopus 로고
    • K-ras point mutation occurs in the early stage of carcinogenesis in lung cancer
    • Sagawa M Saito Y Fujimura S Linnoila RI K-ras point mutation occurs in the early stage of carcinogenesis in lung cancer Br J Cancer 1998 77 720 3
    • (1998) Br J Cancer , vol.77 , pp. 720-723
    • Sagawa, M.1    Saito, Y.2    Fujimura, S.3    Linnoila, R.I.4
  • 24
    • 0025099493 scopus 로고
    • Reaction products in hemoglobin and DNA after in vitro treatment with ethylene oxide and N-(2-hydroxyethyl)-N-nitrosourea
    • Segerback D Reaction products in hemoglobin and DNA after in vitro treatment with ethylene oxide and N-(2-hydroxyethyl)-N-nitrosourea Carcinogenesis 1990 11 307 12
    • (1990) Carcinogenesis , vol.11 , pp. 307-312
    • Segerback, D.1
  • 26
    • 0027433197 scopus 로고
    • Ethylene oxide: an assessment of the epidemiological evidence on carcinogenicity
    • Shore RE Gardner MJ Pannett B Ethylene oxide: an assessment of the epidemiological evidence on carcinogenicity Br J Ind Med 1993 50 971 97
    • (1993) Br J Ind Med , vol.50 , pp. 971-997
    • Shore, R.E.1    Gardner, M.J.2    Pannett, B.3
  • 27
    • 0029039660 scopus 로고
    • Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months
    • Sills RC Hong HL Greenwell A Herbert RA Boorman GA Devereux TR Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months Carcinogenesis 1995 16 1623 8
    • (1995) Carcinogenesis , vol.16 , pp. 1623-1628
    • Sills, R.C.1    Hong, H.L.2    Greenwell, A.3    Herbert, R.A.4    Boorman, G.A.5    Devereux, T.R.6
  • 28
    • 0032994402 scopus 로고    scopus 로고
    • High frequency of codon 61 K-ras A T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene
    • Sills RC Hong HL Melnick RL Boorman GA Devereux TR High frequency of codon 61 K-ras A T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene Carcinogenesis 1999 20 657 62
    • (1999) Carcinogenesis , vol.20 , pp. 657-662
    • Sills, R.C.1    Hong, H.L.2    Melnick, R.L.3    Boorman, G.A.4    Devereux, T.R.5
  • 29
    • 0030807682 scopus 로고    scopus 로고
    • Assessment of the in vivo mutagenicity of ethylene oxide in the tissues of B6C3F1 lacI transgenic mice following inhalation exposure
    • Sisk SC Pluta LJ Meyer KG Wong BC Recio L Assessment of the in vivo mutagenicity of ethylene oxide in the tissues of B6C3F1 lacI transgenic mice following inhalation exposure Mutat Res 1997 391 153 64
    • (1997) Mutat Res , vol.391 , pp. 153-164
    • Sisk, S.C.1    Pluta, L.J.2    Meyer, K.G.3    Wong, B.C.4    Recio, L.5
  • 33
    • 0033976741 scopus 로고    scopus 로고
    • Formation of DNA adducts and induction of mutagenic effects in rats following 4 weeks inhalation exposure to ethylene oxide as a basis for cancer risk assessment
    • van Sittert NJ Boogaard PJ Natarajan AT Tates AD Ehrenberg LG Tornqvist MA Formation of DNA adducts and induction of mutagenic effects in rats following 4 weeks inhalation exposure to ethylene oxide as a basis for cancer risk assessment Mutat Res 2000 447 27 48
    • (2000) Mutat Res , vol.447 , pp. 27-48
    • van Sittert, N.J.1    Boogaard, P.J.2    Natarajan, A.T.3    Tates, A.D.4    Ehrenberg, L.G.5    Tornqvist, M.A.6
  • 34
    • 0026788021 scopus 로고
    • Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice
    • Walker VE Fennell TR Upton PB Skopek TR Prevost V Shuker DE Swenberg JA Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice Cancer Res 1992 52 4328 34
    • (1992) Cancer Res , vol.52 , pp. 4328-4334
    • Walker, V.E.1    Fennell, T.R.2    Upton, P.B.3    Skopek, T.R.4    Prevost, V.5    Shuker, D.E.6    Swenberg, J.A.7
  • 36
    • 0032841761 scopus 로고    scopus 로고
    • Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents
    • Wu KY Ranasinghe A Upton PB Walker VE Swenberg JA Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents Carcinogenesis 1999 20 1787 92
    • (1999) Carcinogenesis , vol.20 , pp. 1787-1792
    • Wu, K.Y.1    Ranasinghe, A.2    Upton, P.B.3    Walker, V.E.4    Swenberg, J.A.5


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