-
1
-
-
0030025982
-
In vivo and in vitro kinetics of ethylene oxide metabolism in rats and mice
-
Brown CD Wong BA Fennell TR In vivo and in vitro kinetics of ethylene oxide metabolism in rats and mice Toxicol Appl Pharmacol 1996 136 8 19
-
(1996)
Toxicol Appl Pharmacol
, vol.136
, pp. 8-19
-
-
Brown, C.D.1
Wong, B.A.2
Fennell, T.R.3
-
2
-
-
0026096577
-
Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse
-
Devereux TR Anderson MW Belinsky SA Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse Carcinogenesis 1991 12 299 303
-
(1991)
Carcinogenesis
, vol.12
, pp. 299-303
-
-
Devereux, T.R.1
Anderson, M.W.2
Belinsky, S.A.3
-
3
-
-
0027314749
-
Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride
-
Devereux TR Foley JF Maronpot RR Kari F Anderson MW Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride Carcinogenesis 1993 14 795 801
-
(1993)
Carcinogenesis
, vol.14
, pp. 795-801
-
-
Devereux, T.R.1
Foley, J.F.2
Maronpot, R.R.3
Kari, F.4
Anderson, M.W.5
-
4
-
-
0032035009
-
Oncogene and tumour suppressor gene expression changes in persons exposed to ethylene oxide
-
Ember I Kiss I Malovics I Oncogene and tumour suppressor gene expression changes in persons exposed to ethylene oxide Eur J Cancer Prev 1998 7 167 8
-
(1998)
Eur J Cancer Prev
, vol.7
, pp. 167-168
-
-
Ember, I.1
Kiss, I.2
Malovics, I.3
-
5
-
-
0028043929
-
Activation of H-ras is prevalent in 1,3-butadiene-induced and spontaneously occurring murine Harderian gland tumors
-
Goodrow TL Nichols WW Storer RD Anderson MW Maronpot RR Activation of H-ras is prevalent in 1,3-butadiene-induced and spontaneously occurring murine Harderian gland tumors Carcinogenesis 1994 15 2665 7
-
(1994)
Carcinogenesis
, vol.15
, pp. 2665-2667
-
-
Goodrow, T.L.1
Nichols, W.W.2
Storer, R.D.3
Anderson, M.W.4
Maronpot, R.R.5
-
6
-
-
0034823814
-
High frequency of ras mutations in forestomach and lung tumors of B6C3F1 mice exposed to 1-amino-2,4-dibromoanthraquinone for 2 years
-
Hayashi S Hong HH Toyoda K Ton TV Devereux TR Maronpot RR Huff J Sills RC High frequency of ras mutations in forestomach and lung tumors of B6C3F1 mice exposed to 1-amino-2,4-dibromoanthraquinone for 2 years Toxicol Pathol 2001 29 422 9
-
(2001)
Toxicol Pathol
, vol.29
, pp. 422-429
-
-
Hayashi, S.1
Hong, H.H.2
Toyoda, K.3
Ton, T.V.4
Devereux, T.R.5
Maronpot, R.R.6
Huff, J.7
Sills, R.C.8
-
7
-
-
0028006345
-
Glycolaldehyde causes DNA-protein crosslinks: a new aspect of ethylene oxide genotoxicity
-
Hengstler JG Fuchs J Gebhard S Oesch F Glycolaldehyde causes DNA-protein crosslinks: a new aspect of ethylene oxide genotoxicity Mutat Res 1994 304 229 34
-
(1994)
Mutat Res
, vol.304
, pp. 229-234
-
-
Hengstler, J.G.1
Fuchs, J.2
Gebhard, S.3
Oesch, F.4
-
8
-
-
0031408925
-
Both K-ras and H-ras protooncogene mutations are associated with Harderian gland tumorigenesis in B6C3F1 mice exposed to isoprene for 26 weeks
-
Hong HL Devereux TR Melnick RL Eldridge SR Greenwell A Haseman J Boorman GA Sills RC Both K-ras and H-ras protooncogene mutations are associated with Harderian gland tumorigenesis in B6C3F1 mice exposed to isoprene for 26 weeks Carcinogenesis 1997 18 783 9
-
(1997)
Carcinogenesis
, vol.18
, pp. 783-789
-
-
Hong, H.L.1
Devereux, T.R.2
Melnick, R.L.3
Eldridge, S.R.4
Greenwell, A.5
Haseman, J.6
Boorman, G.A.7
Sills, R.C.8
-
9
-
-
0028691804
-
IARC working group on the evaluation of carcinogenic risks to humans: some industrial chemicals. Lyon, 15–22 February 1994
-
IARC IARC working group on the evaluation of carcinogenic risks to humans: some industrial chemicals. Lyon, 15–22 February 1994 IARC Monogr Eval Carcinog Risks Hum 1994 60 1 560
-
(1994)
IARC Monogr Eval Carcinog Risks Hum
, vol.60
, pp. 1-560
-
-
-
10
-
-
0029111612
-
Role of point mutation of the K-ras gene in tumorigenesis of B6C3F1 mouse lung lesions induced by urethane
-
Kawano R Nishisaka T Takeshima Y Yonehara S Inai K Role of point mutation of the K-ras gene in tumorigenesis of B6C3F1 mouse lung lesions induced by urethane Jpn J Cancer Res 1995 86 802 10
-
(1995)
Jpn J Cancer Res
, vol.86
, pp. 802-810
-
-
Kawano, R.1
Nishisaka, T.2
Takeshima, Y.3
Yonehara, S.4
Inai, K.5
-
11
-
-
0026809854
-
Cytogenetic study of persons occupationally exposed to ethylene oxide
-
Lerda D Rizzi R Cytogenetic study of persons occupationally exposed to ethylene oxide Mutat Res 1992 281 31 7
-
(1992)
Mutat Res
, vol.281
, pp. 31-37
-
-
Lerda, D.1
Rizzi, R.2
-
12
-
-
0026773508
-
In vitro reaction of ethylene oxide with DNA and characterization of DNA adducts
-
Li F Segal A Solomon JJ In vitro reaction of ethylene oxide with DNA and characterization of DNA adducts Chem Biol Interact 1992 83 35 54
-
(1992)
Chem Biol Interact
, vol.83
, pp. 35-54
-
-
Li, F.1
Segal, A.2
Solomon, J.J.3
-
13
-
-
0035978608
-
Induction and persistence of micronuclei, sister-chromatid exchanges and chromosomal aberrations in splenocytes and bone-marrow cells of rats exposed to ethylene oxide
-
Lorenti Garcia C Darroudi F Tates AD Natarajan AT Induction and persistence of micronuclei, sister-chromatid exchanges and chromosomal aberrations in splenocytes and bone-marrow cells of rats exposed to ethylene oxide Mutat Res 2001 492 59 67
-
(2001)
Mutat Res
, vol.492
, pp. 59-67
-
-
Lorenti Garcia, C.1
Darroudi, F.2
Tates, A.D.3
Natarajan, A.T.4
-
14
-
-
21444458657
-
Involvement of the ras genes in female genital tract cancer
-
Mammas IN Zafiropoulos A Spandidos DA Involvement of the ras genes in female genital tract cancer Int J Oncol 2005 26 1241 55
-
(2005)
Int J Oncol
, vol.26
, pp. 1241-1255
-
-
Mammas, I.N.1
Zafiropoulos, A.2
Spandidos, D.A.3
-
15
-
-
0036965324
-
Carcinogenicity and mechanistic insights on the behavior of epoxides and epoxide-forming chemicals
-
Melnick RL Carcinogenicity and mechanistic insights on the behavior of epoxides and epoxide-forming chemicals Ann N Y Acad Sci 2002 982 177 89
-
(2002)
Ann N Y Acad Sci
, vol.982
, pp. 177-189
-
-
Melnick, R.L.1
-
16
-
-
0013887614
-
Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules
-
Miller EC Miller JA Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules Pharmacol Rev 1966 18 805 38
-
(1966)
Pharmacol Rev
, vol.18
, pp. 805-838
-
-
Miller, E.C.1
Miller, J.A.2
-
17
-
-
0029075553
-
Rare occurrence of p53 and ras gene mutations in preneoplastic and neoplastic mouse endometrial lesions induced by N-methyl-N-nitrosourea and 17 beta-estradiol
-
Murase T Niwa K Morishita S Itoh N Mori H Tanaka T Tamaya T Rare occurrence of p53 and ras gene mutations in preneoplastic and neoplastic mouse endometrial lesions induced by N-methyl-N-nitrosourea and 17 beta-estradiol Cancer Lett 1995 92 223 7
-
(1995)
Cancer Lett
, vol.92
, pp. 223-227
-
-
Murase, T.1
Niwa, K.2
Morishita, S.3
Itoh, N.4
Mori, H.5
Tanaka, T.6
Tamaya, T.7
-
19
-
-
0038032435
-
-
11, Research Triangle Park, NC, U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program
-
NTP Report on Carcinogens 2004 11 Research Triangle Park, NC U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program
-
(2004)
Report on Carcinogens
-
-
-
20
-
-
0025670013
-
Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas
-
Nuzum EO Malkinson AM Beer DG Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas Mol Carcinog 1990 3 287 95
-
(1990)
Mol Carcinog
, vol.3
, pp. 287-295
-
-
Nuzum, E.O.1
Malkinson, A.M.2
Beer, D.G.3
-
22
-
-
2942583950
-
In vivo mutagenicity and mutation spectrum in the bone marrow and testes of B6C3F1 lacI transgenic mice following inhalation exposure to ethylene oxide
-
Recio L Donner M Abernethy D Pluta L Steen AM Wong BA James A Preston RJ In vivo mutagenicity and mutation spectrum in the bone marrow and testes of B6C3F1 lacI transgenic mice following inhalation exposure to ethylene oxide Mutagenesis 2004 19 215 22
-
(2004)
Mutagenesis
, vol.19
, pp. 215-222
-
-
Recio, L.1
Donner, M.2
Abernethy, D.3
Pluta, L.4
Steen, A.M.5
Wong, B.A.6
James, A.7
Preston, R.J.8
-
23
-
-
0031886443
-
K-ras point mutation occurs in the early stage of carcinogenesis in lung cancer
-
Sagawa M Saito Y Fujimura S Linnoila RI K-ras point mutation occurs in the early stage of carcinogenesis in lung cancer Br J Cancer 1998 77 720 3
-
(1998)
Br J Cancer
, vol.77
, pp. 720-723
-
-
Sagawa, M.1
Saito, Y.2
Fujimura, S.3
Linnoila, R.I.4
-
24
-
-
0025099493
-
Reaction products in hemoglobin and DNA after in vitro treatment with ethylene oxide and N-(2-hydroxyethyl)-N-nitrosourea
-
Segerback D Reaction products in hemoglobin and DNA after in vitro treatment with ethylene oxide and N-(2-hydroxyethyl)-N-nitrosourea Carcinogenesis 1990 11 307 12
-
(1990)
Carcinogenesis
, vol.11
, pp. 307-312
-
-
Segerback, D.1
-
26
-
-
0027433197
-
Ethylene oxide: an assessment of the epidemiological evidence on carcinogenicity
-
Shore RE Gardner MJ Pannett B Ethylene oxide: an assessment of the epidemiological evidence on carcinogenicity Br J Ind Med 1993 50 971 97
-
(1993)
Br J Ind Med
, vol.50
, pp. 971-997
-
-
Shore, R.E.1
Gardner, M.J.2
Pannett, B.3
-
27
-
-
0029039660
-
Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months
-
Sills RC Hong HL Greenwell A Herbert RA Boorman GA Devereux TR Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months Carcinogenesis 1995 16 1623 8
-
(1995)
Carcinogenesis
, vol.16
, pp. 1623-1628
-
-
Sills, R.C.1
Hong, H.L.2
Greenwell, A.3
Herbert, R.A.4
Boorman, G.A.5
Devereux, T.R.6
-
28
-
-
0032994402
-
High frequency of codon 61 K-ras A T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene
-
Sills RC Hong HL Melnick RL Boorman GA Devereux TR High frequency of codon 61 K-ras A T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene Carcinogenesis 1999 20 657 62
-
(1999)
Carcinogenesis
, vol.20
, pp. 657-662
-
-
Sills, R.C.1
Hong, H.L.2
Melnick, R.L.3
Boorman, G.A.4
Devereux, T.R.5
-
29
-
-
0030807682
-
Assessment of the in vivo mutagenicity of ethylene oxide in the tissues of B6C3F1 lacI transgenic mice following inhalation exposure
-
Sisk SC Pluta LJ Meyer KG Wong BC Recio L Assessment of the in vivo mutagenicity of ethylene oxide in the tissues of B6C3F1 lacI transgenic mice following inhalation exposure Mutat Res 1997 391 153 64
-
(1997)
Mutat Res
, vol.391
, pp. 153-164
-
-
Sisk, S.C.1
Pluta, L.J.2
Meyer, K.G.3
Wong, B.C.4
Recio, L.5
-
31
-
-
0025873394
-
Biological and chemical monitoring of occupational exposure to ethylene oxide
-
Tates AD Grummt T Tornqvist M Farmer PB van Dam FJ van Mossel H Schoemaker HM Osterman-Golkar S Uebel C Tang YS Zwinderman AH Natarajan AT Ehrenberg L Biological and chemical monitoring of occupational exposure to ethylene oxide Mutat Res 1991 250 483 97
-
(1991)
Mutat Res
, vol.250
, pp. 483-497
-
-
Tates, A.D.1
Grummt, T.2
Tornqvist, M.3
Farmer, P.B.4
van Dam, F.J.5
van Mossel, H.6
Schoemaker, H.M.7
Osterman-Golkar, S.8
Uebel, C.9
Tang, Y.S.10
Zwinderman, A.H.11
Natarajan, A.T.12
Ehrenberg, L.13
-
32
-
-
0033382001
-
Measurement of HPRT mutations in splenic lymphocytes and haemoglobin adducts in erythrocytes of Lewis rats exposed to ethylene oxide
-
Tates AD van Dam FJ Natarajan AT van Teylingen CM de Zwart FA Zwinderman AH van Sittert NJ Nilsen A Nilsen OG Zahlsen K Magnusson AL Tornqvist M Measurement of HPRT mutations in splenic lymphocytes and haemoglobin adducts in erythrocytes of Lewis rats exposed to ethylene oxide Mutat Res 1999 431 397 415
-
(1999)
Mutat Res
, vol.431
, pp. 397-415
-
-
Tates, A.D.1
van Dam, F.J.2
Natarajan, A.T.3
van Teylingen, C.M.4
de Zwart, F.A.5
Zwinderman, A.H.6
van Sittert, N.J.7
Nilsen, A.8
Nilsen, O.G.9
Zahlsen, K.10
Magnusson, A.L.11
Tornqvist, M.12
-
33
-
-
0033976741
-
Formation of DNA adducts and induction of mutagenic effects in rats following 4 weeks inhalation exposure to ethylene oxide as a basis for cancer risk assessment
-
van Sittert NJ Boogaard PJ Natarajan AT Tates AD Ehrenberg LG Tornqvist MA Formation of DNA adducts and induction of mutagenic effects in rats following 4 weeks inhalation exposure to ethylene oxide as a basis for cancer risk assessment Mutat Res 2000 447 27 48
-
(2000)
Mutat Res
, vol.447
, pp. 27-48
-
-
van Sittert, N.J.1
Boogaard, P.J.2
Natarajan, A.T.3
Tates, A.D.4
Ehrenberg, L.G.5
Tornqvist, M.A.6
-
34
-
-
0026788021
-
Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice
-
Walker VE Fennell TR Upton PB Skopek TR Prevost V Shuker DE Swenberg JA Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice Cancer Res 1992 52 4328 34
-
(1992)
Cancer Res
, vol.52
, pp. 4328-4334
-
-
Walker, V.E.1
Fennell, T.R.2
Upton, P.B.3
Skopek, T.R.4
Prevost, V.5
Shuker, D.E.6
Swenberg, J.A.7
-
35
-
-
0033851430
-
Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide
-
Walker VE Wu KY Upton PB Ranasinghe A Scheller N Cho MH Vergnes JS Skopek TR Swenberg JA Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide Carcinogenesis 2000 21 1661 9
-
(2000)
Carcinogenesis
, vol.21
, pp. 1661-1669
-
-
Walker, V.E.1
Wu, K.Y.2
Upton, P.B.3
Ranasinghe, A.4
Scheller, N.5
Cho, M.H.6
Vergnes, J.S.7
Skopek, T.R.8
Swenberg, J.A.9
-
36
-
-
0032841761
-
Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents
-
Wu KY Ranasinghe A Upton PB Walker VE Swenberg JA Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents Carcinogenesis 1999 20 1787 92
-
(1999)
Carcinogenesis
, vol.20
, pp. 1787-1792
-
-
Wu, K.Y.1
Ranasinghe, A.2
Upton, P.B.3
Walker, V.E.4
Swenberg, J.A.5
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