메뉴 건너뛰기




Volumn 52, Issue 3, 2007, Pages 650-658

N-acetyl-L-glutamine, a liquid-stable source of glutamine, partially prevents changes in body weight and on intestinal immunity induced by protein energy malnutrition in pigs

Author keywords

Glutamine; Intestinal immunity; Malnutrition; N acetyl L glutamine; Pig

Indexed keywords

CALCIUM; CASEIN; GLUTAMINE; N ACETYLGLUTAMIC ACID;

EID: 33847196458     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-9500-y     Document Type: Article
Times cited : (22)

References (42)
  • 3
    • 0034842396 scopus 로고    scopus 로고
    • The effect of glutamine supplementation in patients following effective surgery and accidental injury
    • Wilmore DW (2001) The effect of glutamine supplementation in patients following effective surgery and accidental injury. J Nutr 131(9 Suppl):2543S-2549S
    • (2001) J Nutr , vol.131 , Issue.9 SUPPL.
    • Wilmore, D.W.1
  • 4
    • 0034843181 scopus 로고    scopus 로고
    • Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?
    • Newsholme P (2001) Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection? J Nutr 131(9 Suppl):2515S-2522S
    • (2001) J Nutr , vol.131 , Issue.9 SUPPL.
    • Newsholme, P.1
  • 5
    • 13844254526 scopus 로고    scopus 로고
    • The role of glutamine in intensive care unit patients: Mechanisms of action and clinical outcome
    • Coeffier M, Dechelotte P (2005) The role of glutamine in intensive care unit patients: mechanisms of action and clinical outcome. Nutr Rev 63:65-69
    • (2005) Nutr Rev , vol.63 , pp. 65-69
    • Coeffier, M.1    Dechelotte, P.2
  • 7
    • 0033489873 scopus 로고    scopus 로고
    • Glutamine and the immune system
    • Calder PC, Yaqoob P (1999) Glutamine and the immune system. Amino Acids 17:227-241
    • (1999) Amino Acids , vol.17 , pp. 227-241
    • Calder, P.C.1    Yaqoob, P.2
  • 8
    • 0036166474 scopus 로고    scopus 로고
    • Glutamine: Essential for immune nutrition in the critically ill
    • Andrews FJ, Griffiths RD (2002) Glutamine: essential for immune nutrition in the critically ill. Br J Nutr 87(Suppl 1):S3-8
    • (2002) Br J Nutr , vol.87 , Issue.SUPPL. 1
    • Andrews, F.J.1    Griffiths, R.D.2
  • 9
    • 0031845758 scopus 로고    scopus 로고
    • Role of glutamine in immunologic response
    • Wilmore DW, Shabert JK (1998) Role of glutamine in immunologic response. Nutrition 14:618-626
    • (1998) Nutrition , vol.14 , pp. 618-626
    • Wilmore, D.W.1    Shabert, J.K.2
  • 11
    • 0025256045 scopus 로고
    • Glutathione is required for intestinal function
    • Martensson J, Jain A, Meister A (1990) Glutathione is required for intestinal function. Proc Natl Acad Sci 87:1715-1719
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 1715-1719
    • Martensson, J.1    Jain, A.2    Meister, A.3
  • 12
    • 33847187600 scopus 로고
    • Damage and repair of the small intestinal mucosa in diarrhea and malnutrition
    • Lebenthal E ed, New York: Raven Press; pp
    • Brunser O, Araya M, Espinosa J (1991) Damage and repair of the small intestinal mucosa in diarrhea and malnutrition. In: Lebenthal E (ed) Textbook of gastroenterology and nutrition in infancy New York: Raven Press; pp 535-544
    • (1991) Textbook of gastroenterology and nutrition in infancy , pp. 535-544
    • Brunser, O.1    Araya, M.2    Espinosa, J.3
  • 13
    • 0031915009 scopus 로고    scopus 로고
    • Severe malnutrition alters lipid composition and fatty acid profile of small intestine in newborn piglets
    • López-Pedrosa JM, Torres MI, Fernández MI, Ríos A, Gil A (1998) Severe malnutrition alters lipid composition and fatty acid profile of small intestine in newborn piglets. J Nutr 128:224-233
    • (1998) J Nutr , vol.128 , pp. 224-233
    • López-Pedrosa, J.M.1    Torres, M.I.2    Fernández, M.I.3    Ríos, A.4    Gil, A.5
  • 14
    • 0025456060 scopus 로고
    • Glutamine-containing dipeptides in parenteral nutrition
    • Furst P, Albers S, Stehle P (1990) Glutamine-containing dipeptides in parenteral nutrition. J Parenter Enteral Nutr 14(4 Suppl):118S-124S
    • (1990) J Parenter Enteral Nutr , vol.14 , Issue.4 SUPPL.
    • Furst, P.1    Albers, S.2    Stehle, P.3
  • 15
    • 0343329868 scopus 로고    scopus 로고
    • Glutamine dipeptides in clinical nutrition
    • Furst P, Pogan K, Stehle P (1997) Glutamine dipeptides in clinical nutrition. Nutrition 13:731-737
    • (1997) Nutrition , vol.13 , pp. 731-737
    • Furst, P.1    Pogan, K.2    Stehle, P.3
  • 16
    • 0034849365 scopus 로고    scopus 로고
    • New developments in glutamine delivery
    • Furst P (2001) New developments in glutamine delivery. J Nutr 131(9 Suppl):2562S-2568S
    • (2001) J Nutr , vol.131 , Issue.9 SUPPL.
    • Furst, P.1
  • 17
    • 3042595678 scopus 로고    scopus 로고
    • Gut mucosal and plasma concentrations of glutamine: A comparison between two enriched enteral feeding solutions in critically ill patients
    • Preiser JC, Peres-Bota D, Eisendrath P, Vincent JL, Van Gossum A (2003) Gut mucosal and plasma concentrations of glutamine: a comparison between two enriched enteral feeding solutions in critically ill patients. Nutr J 2:13
    • (2003) Nutr J , vol.2 , pp. 13
    • Preiser, J.C.1    Peres-Bota, D.2    Eisendrath, P.3    Vincent, J.L.4    Van Gossum, A.5
  • 18
    • 0036186379 scopus 로고    scopus 로고
    • Stability of N-acetylglutamine and glutamine in aqueous solution and in a liquid nutritional product by an improved HPLC method
    • Snowden MK, Baxter JH, Mamula Bergana M, Reyzer I, Pound V (2002) Stability of N-acetylglutamine and glutamine in aqueous solution and in a liquid nutritional product by an improved HPLC method. J Food Sci 67:384-389
    • (2002) J Food Sci , vol.67 , pp. 384-389
    • Snowden, M.K.1    Baxter, J.H.2    Mamula Bergana, M.3    Reyzer, I.4    Pound, V.5
  • 19
    • 8744222482 scopus 로고    scopus 로고
    • Absorption of enterally administered N-acetyl-L-glutamine versus glutamine in pigs
    • Arnaud A, Ramírez M, Baxter JH, Angulo AJ (2004) Absorption of enterally administered N-acetyl-L-glutamine versus glutamine in pigs. Clin Nutr 23:1303-1312
    • (2004) Clin Nutr , vol.23 , pp. 1303-1312
    • Arnaud, A.1    Ramírez, M.2    Baxter, J.H.3    Angulo, A.J.4
  • 20
    • 26044448138 scopus 로고    scopus 로고
    • Topography of digestive enzymes in the pigs small intestine at the early stages of ontogeny in the norm and pathology
    • Lindberg JE, Ogle B eds, New York: CABI Publishing, pp
    • Egorova VV, Egorova GG, Lasarenko LV, Timofeeva NM, Sherlakov (2001) Topography of digestive enzymes in the pigs small intestine at the early stages of ontogeny in the norm and pathology. In: Lindberg JE, Ogle B (eds) Digestive Physiology of Pigs New York: CABI Publishing, pp 49-51
    • (2001) Digestive Physiology of Pigs , pp. 49-51
    • Egorova, V.V.1    Egorova, G.G.2    Lasarenko, L.V.3    Timofeeva, N.M.4    Sherlakov5
  • 21
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation ofmicrogram quantities utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation ofmicrogram quantities utilizing the principle of protein-dye binding. Anan Biochem 72: 248-254
    • (1976) Anan Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 22
    • 0018850985 scopus 로고
    • A simple, rapid and sensitive DNA assay procedure
    • Labarca C, Paigen K (1980) A simple, rapid and sensitive DNA assay procedure. Anal Biochem 102:344-354
    • (1980) Anal Biochem , vol.102 , pp. 344-354
    • Labarca, C.1    Paigen, K.2
  • 24
    • 0016275313 scopus 로고
    • Glutathione-S-transferases, the first enzymatic step inmercapturie acid formation
    • Habig WH, Pabst MJ, Jakoby WB (1984) Glutathione-S-transferases, the first enzymatic step inmercapturie acid formation. J Biol Chem 294:7130-7139
    • (1984) J Biol Chem , vol.294 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 25
    • 0001362865 scopus 로고
    • Assays for glutathione peroxidase
    • Flohé L, Günzler WA (1985) Assays for glutathione peroxidase. Methods Enzymol 105:209-221
    • (1985) Methods Enzymol , vol.105 , pp. 209-221
    • Flohé, L.1    Günzler, W.A.2
  • 26
    • 0022272493 scopus 로고
    • Determination of glutathione and glutathione disulfide in biological samples
    • Anderson ME (1985) Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol 113:548-559
    • (1985) Methods Enzymol , vol.113 , pp. 548-559
    • Anderson, M.E.1
  • 27
    • 0029881090 scopus 로고    scopus 로고
    • Dietary restriction induces biochemical and morphometric changes in the small intestine of nursing piglets
    • Nuñez MC, Bueno JD, Ayudarte MV, Almendros A, Rios A, Suarez MD, Gil A (1996) Dietary restriction induces biochemical and morphometric changes in the small intestine of nursing piglets. J Nutr 126:933-944
    • (1996) J Nutr , vol.126 , pp. 933-944
    • Nuñez, M.C.1    Bueno, J.D.2    Ayudarte, M.V.3    Almendros, A.4    Rios, A.5    Suarez, M.D.6    Gil, A.7
  • 28
    • 0028240887 scopus 로고
    • T lymphocytes in host defense against bacterial translocation from the gastrointestinal tract
    • Gautreaux MD, Deitch EA, Berg RD (1994) T lymphocytes in host defense against bacterial translocation from the gastrointestinal tract. Infect Immun 62:2874-2884
    • (1994) Infect Immun , vol.62 , pp. 2874-2884
    • Gautreaux, M.D.1    Deitch, E.A.2    Berg, R.D.3
  • 30
    • 0034332046 scopus 로고    scopus 로고
    • Nutritional and pharmacological enhancement of gut-associated lymphoid tissue
    • Hanna MK, Kudsk KA (2000) Nutritional and pharmacological enhancement of gut-associated lymphoid tissue. Can J Gastroenterol 14(Suppl D):145D-151D
    • (2000) Can J Gastroenterol , vol.14 , Issue.SUPPL. D
    • Hanna, M.K.1    Kudsk, K.A.2
  • 31
    • 4944259806 scopus 로고    scopus 로고
    • Does enteral nutrition compared to parenteral nutrition results in better outcomes in critically ill adult patients? A systematic review of the literature
    • Gramlich L, Kichian K, Pinilla J, Rodych NJ, Dhaliwal R, Heyland DK (2004) Does enteral nutrition compared to parenteral nutrition results in better outcomes in critically ill adult patients? A systematic review of the literature. Nutrition 20:843-848
    • (2004) Nutrition , vol.20 , pp. 843-848
    • Gramlich, L.1    Kichian, K.2    Pinilla, J.3    Rodych, N.J.4    Dhaliwal, R.5    Heyland, D.K.6
  • 32
    • 0023813513 scopus 로고
    • Utilization of N-acetyl-L-glutamine during long-term parenteral nutrition in growing rats: Significance of glutamine for weight and nitrogen balance
    • Neuhäuser-Berthold M, Wirth S, Hellmann U, Bässler KH (1988) Utilization of N-acetyl-L-glutamine during long-term parenteral nutrition in growing rats: significance of glutamine for weight and nitrogen balance. Clin Nutr 7:145-150
    • (1988) Clin Nutr , vol.7 , pp. 145-150
    • Neuhäuser-Berthold, M.1    Wirth, S.2    Hellmann, U.3    Bässler, K.H.4
  • 34
    • 0032488513 scopus 로고    scopus 로고
    • Recent trends in glutathione biochemistry-glutathione-protein interactions: A molecular link between oxidative stress and cell proliferation?
    • Cotgreave IA, Gerdes RG (1998) Recent trends in glutathione biochemistry-glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation? Biochem Biophys Res Commun 242:1-9
    • (1998) Biochem Biophys Res Commun , vol.242 , pp. 1-9
    • Cotgreave, I.A.1    Gerdes, R.G.2
  • 35
    • 0242290219 scopus 로고    scopus 로고
    • Aw TY (2003) Cellular redox: a modulator of intestinal epithelial cell proliferation. News Physiol Sci 18:201-203
    • Aw TY (2003) Cellular redox: a modulator of intestinal epithelial cell proliferation. News Physiol Sci 18:201-203
  • 36
    • 0037285906 scopus 로고    scopus 로고
    • Chronic exposure to subtoxic levels of peroxidized lipids suppresses mucosal cell turnover in rat small intestine and reversal by glutathione
    • Tsunada S, Iwakiri R, Noda T, Fujimoto K, Fuseler J, Rhoads CA, Aw TY (2003) Chronic exposure to subtoxic levels of peroxidized lipids suppresses mucosal cell turnover in rat small intestine and reversal by glutathione. Dig Dis Sci 48:210-222
    • (2003) Dig Dis Sci , vol.48 , pp. 210-222
    • Tsunada, S.1    Iwakiri, R.2    Noda, T.3    Fujimoto, K.4    Fuseler, J.5    Rhoads, C.A.6    Aw, T.Y.7
  • 37
    • 0031007679 scopus 로고    scopus 로고
    • Effect of glutamine-enriched total parenteral nutrition on small intestinal gut-associated lymphoid tissue and upper respiratory tract immunity
    • Li J, Kudsk KA, Janu P, Renegar KB (1997) Effect of glutamine-enriched total parenteral nutrition on small intestinal gut-associated lymphoid tissue and upper respiratory tract immunity. Surgery 121:542-549
    • (1997) Surgery , vol.121 , pp. 542-549
    • Li, J.1    Kudsk, K.A.2    Janu, P.3    Renegar, K.B.4
  • 38
    • 0031964752 scopus 로고    scopus 로고
    • Glycil-L-glutamine- enriched total parenteral nutrition maintains small intestine gut-associated lymphoid tissue and upper respiratory tract immunity
    • Li J, King BK, Janu PG, Renegar KB, Kudsk KA (1998) Glycil-L-glutamine- enriched total parenteral nutrition maintains small intestine gut-associated lymphoid tissue and upper respiratory tract immunity. J Parenter Enteral Nutr 22:31-36
    • (1998) J Parenter Enteral Nutr , vol.22 , pp. 31-36
    • Li, J.1    King, B.K.2    Janu, P.G.3    Renegar, K.B.4    Kudsk, K.A.5
  • 39
    • 0033659162 scopus 로고    scopus 로고
    • Glutamine-enriched total parenteral nutrition maintains intestinal interleukin-4 and mucosal immunoglobulin A levels
    • Kudsk KA, Wu Y, Fukatsu K, Zarzaur BL, Johnason CD, Wang R, Hanna MK (2000) Glutamine-enriched total parenteral nutrition maintains intestinal interleukin-4 and mucosal immunoglobulin A levels. J Parenter Enteral Nutr 24:270-274
    • (2000) J Parenter Enteral Nutr , vol.24 , pp. 270-274
    • Kudsk, K.A.1    Wu, Y.2    Fukatsu, K.3    Zarzaur, B.L.4    Johnason, C.D.5    Wang, R.6    Hanna, M.K.7
  • 40
    • 0034941504 scopus 로고    scopus 로고
    • Oral feeding with glutamine prevents lymphocyte and glutathion depletion of Peyer's patches in endotoxemic mice
    • Manhart N, Vierlinger K, Spittler A, Bergmeister H, Sautner T, Roth E (2001) Oral feeding with glutamine prevents lymphocyte and glutathion depletion of Peyer's patches in endotoxemic mice. Ann Surg 234:92-97
    • (2001) Ann Surg , vol.234 , pp. 92-97
    • Manhart, N.1    Vierlinger, K.2    Spittler, A.3    Bergmeister, H.4    Sautner, T.5    Roth, E.6
  • 41
    • 1342329222 scopus 로고    scopus 로고
    • Glutamine supplementation enhances mucosal immunity in rats with gut-derived sepsis
    • Lai YN, Yeh SL, Lin MT, Shang HF, Yeh CL, Chen WJ (2004) Glutamine supplementation enhances mucosal immunity in rats with gut-derived sepsis. Nutrition 20:286-291
    • (2004) Nutrition , vol.20 , pp. 286-291
    • Lai, Y.N.1    Yeh, S.L.2    Lin, M.T.3    Shang, H.F.4    Yeh, C.L.5    Chen, W.J.6
  • 42
    • 0033665119 scopus 로고    scopus 로고
    • Plasma glutamine response to enteral administration of L-glutamine in human volunteers (free glutamine versus protein-bound glutamine)
    • Boza JJ, Maire JC, Bovetto L, Ballevre O (2000) Plasma glutamine response to enteral administration of L-glutamine in human volunteers (free glutamine versus protein-bound glutamine). Nutrition 16:1037-1042
    • (2000) Nutrition , vol.16 , pp. 1037-1042
    • Boza, J.J.1    Maire, J.C.2    Bovetto, L.3    Ballevre, O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.