Ethanol alters access to the cell nucleus

Pflugers Archiv European Journal of Physiology

Volumn 453, Issue 6, 2007, Pages 809-818

  Schäfer, Claudia ^a   Ludwig, Yvonne ^a   Shahin, Victor ^a   Kramer, Armin ^a   Carl, Philippe ^a   Schillers, Hermann ^a   Oberleithner, Hans ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Alcoholism; Atomic force microscopy; Ethanol; Gene expression; Nuclear permeability; Nuclear pore complex

Indexed keywords

ALCOHOL; DACTINOMYCIN; ION; RIBONUCLEASE;

ALCOHOL ABUSE; ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL ISOLATION; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIFFUSION; ELECTRIC RESISTANCE; FEMALE; MACROMOLECULE; NONHUMAN; NUCLEAR PORE; OOCYTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; XENOPUS;

ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYTOPLASM; ETHANOL; FEMALE; MICROSCOPY, ATOMIC FORCE; NUCLEAR PORE; OOCYTES; PERMEABILITY; SIGNAL TRANSDUCTION; XENOPUS LAEVIS;

EID: 33847148017     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-006-0165-3     Document Type: Article

References (32)

1. Albermann L, Shahin V, Ludwig Y, Schafer C, Schillers H, Oberleithner H (2004) Evidence for importin alpha independent nuclear translocation of glucocorticoid receptors in Xenopus laevis oocytes. Cell Physiol Biochem 14:343-350
2. Aschner M, Allen JW, Mutkus LA, Cao C (2001) Ethanol-induced swelling in neonatal rat primary astrocyte cultures. Brain Res 900:219-226
3. Blow JJ Laskey RA (1988) A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature 332:546-548
4. Brahm J (1983) Permeability of human red cells to a homologous series of aliphatic alcohols. Limitations of the continuous flow-tube method. J Gen Physiol 81:283-304
5. Cronshaw JM, Krutchinsky AN, Zhang W, Chait BT, Matunis MJ (2002) Proteomic analysis of the mammalian nuclear pore complex. J Cell Biol 158:915-927
6. Danker T, Schillers H, Storck J, Shahin V, Krämer B, Wilhelmi M, Oberleithner H (1999) Nuclear hourglass technique: novel approach detects electrically open pores in Xenopus laevis oocyte. Proc Natl Acad Sci U S A 96:13531-13535
7. Danker T, Shahin V, Schlune A, Schafer C, Oberleithner H (2001) Electrophoretic plugging of nuclear pores by using the nuclear hourglass technique. J Membr Biol 184:91-99
8. Denning DP, Patel SS, Uversky V, Fink AL, Rexach M (2003) Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded. Proc Natl Acad Sci U S A 100:2450-2455
9. Enss K, Danker T, Schlune A, Buchholz I, Oberleithner H (2003) Passive transport of macromolecules through Xenopus laevis nuclear envelope. J Membr Biol 196:147-155
10. Gayer GG, Gordon A, Miles MF (1991) Ethanol increases tyrosine hydroxylase gene expression in N1E-115 neuroblastoma cells. J Biol Chem 266:22279-22284
11. Goldberg MW, Allen TD (1995) Structural and functional organization of the nuclear envelope. Curr Opin Cell Biol 7:301-309
12. Goldberg MW, Wiese C, Allen TE, Wilson KL (1997) Dimples, pores, star-rings, and thin rings on growing envelopes: evidence for structural intermediates in nuclear pore complex assembly. J Cell Sci 110:409-420
13. Gorlich D, Kutay U (1999) Transport between the cell nucleus and the cytoplasm. Annu Rev Cell Dev Biol 15:607-660
14. Hinshaw JE, Carragher BO, Milligan RA (1992) Architecture and design of the nuclear pore complex. Cell 69:1133-1141
15. Jaggi RD, Franco-Obregon A, Muhlhausser P, Thomas F, Kutay U, Ensslin K (2003) Modulation of nuclear pore topology by transport modifiers. Biophys J 84:665-670
16. Ludwig Y, Schafer C, Kramer A, Albermann L, Oberleithner H, Shahin V (2006) Hot spot formation in the nuclear envelope of oocytes in response to steroids. Cell Physiol Biochem 17:181-192
17. Mattaj IW, Englmeier L (1998) Nucleocytoplasmic transport: the soluble phase. Ann Rev Biochem 67:265-306
18. Mazzanti M, Bustamante JO, Oberleithner H (2001) Electrical dimension of the nuclear envelope. Physiol Rev 81:1-19
19. Miles MF, Diaz JE, DeGuzman VS (1991) Mechanisms of neuronal adaptation to ethanol. Ethanol induces Hsc70 gene transcription in NG108-15 neuroblastoma x glioma cells. J Biol Chem 266:2409-2414
20. Oberleithner H, Schafer C, Shahin V, Albermann L (2003) Route of steroid-activated macromolecules through nuclear pores imaged with atomic force microscopy. Biochem Soc Trans 31:71-75
21. Pante N, Aebi U (1993) The nuclear pore complex. J Cell Biol 122:977-984
22. Peters R (1984) Nucleo-cytoplasmic flux and intracellular mobility in single hepatocytes measured by fluorescence microphotolysis. EMBO J 3:1831-1836
23. Ribbeck K, Gorlich D (2001) Kinetic analysis of translocation through nuclear pore complexes. EMBO J 20:1320-1330
24. Rout MP, Aitchison JD, Suprapto A, Hjertaas K, Zhao Y, Chait BT (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148:635-651
25. Sachinidis A, Gouni-Berthold I, Seul C, Seewald S, Ko Y, Schmitz U, Vetter H (1999) Early intracellular signalling pathway of ethanol in vascular smooth muscle cells. Br J Pharmacol 128:1761-1771
26. Schäfer C, Shahin V, Albermann L, Hug MJ, Reinhardt J, Schillers H, Schneider SW, Oberleithner H (2002) Aldosterone signaling pathway across the nuclear envelope. Proc Natl Acad Sci U S A 99:7154-7159
27. Schneider SW, Matzke R, Radmacher M, Oberleithner H (2004) Shape and volume of living aldosterone-sensitive cells imaged with the atomic force microscope. Methods Mol Biol 242:255-279
28. Shahin V, Danker T, Enss K, Ossig R, Oberleithner H (2001) Evidence for Ca2+- and ATP-sensitive peripheral channels in nuclear pore complexes. FASEB J 15:1895-1901
29. Shahin V, Ludwig Y, Schafer C, Nikova D, Oberleithner H (2005) Glucocorticoids remodel nuclear envelope structure and permeability. J Cell Sci 118:2881-2889
30. Shulga N, Goldfarb DS (2003) Binding dynamics of structural nucleoporins govern nuclear pore complex permeability and may mediate channel gating. Mol Cell Biol 23:534-542
31. Soop T, Ivarsson B, Bjorkroth B, Fomproix N, Masich S, Cordes VC, Daneholt B (2005) Nup153 affects entry of messenger and ribosomal ribonucleoproteins into the nuclear basket during export. Mol Biol Cell 16:5610-5620
32. Wunsch S, Schneider S, Schwab A, Oberleithner H (1993) 20-OH-ecdysone swells nuclear volume by alkalinization in salivary glands of Drosophila melanogaster. Cell Tissue Res 274:145-151