Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death

Journal of Neuroscience

Volumn 27, Issue 7, 2007, Pages 1519-1528

  Cheng, Aiwu ^a   Arumugam, Thiruma V ^a   Liu, Dong ^a   Khatri, Rina G ^a   Mustafa, Khadija ^a   Kwak, Seung ^b   Ling, Huai Ping ^b   Gonzales, Cathleen ^b   Xin, Ouyang ^a   Jo, Dong Gyu ^a,c   Guo, Zhihong ^a   Mark, Robert J ^b,e   Mattson, Mark P ^a,d  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b PFIZER INC   (United States)

^c Sungkyunkwan University   (South Korea)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Bcl xl; Cerebral ischemia; Neuronal cell death; Pancortin; Stroke; WAVE1

Indexed keywords

BRAIN PROTEIN; CYTOCHROME C; PANCORTIN 2; PROTEIN BAX; PROTEIN BCL XL; REGULATOR PROTEIN; UNCLASSIFIED DRUG; WISKOTT ALDRICH SYNDROME PROTEIN VERPROLIN HOMOLOGOUS 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; BRAIN NERVE CELL; CEREBROVASCULAR ACCIDENT; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; ENZYME RELEASE; HUMAN; HUMAN CELL; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANIMALS; BCL-X PROTEIN; BLOTTING, WESTERN; BRAIN ISCHEMIA; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; CYTOCHROMES C; EMBRYO; EXTRACELLULAR MATRIX PROTEINS; FUNCTIONAL LATERALITY; GLYCOPROTEINS; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA; NEURONS; RATS; RATS, WISTAR; TIME FACTORS; WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY;

EID: 33847127964     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5154-06.2007     Document Type: Article

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