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Volumn 64, Issue 4, 2007, Pages 363-368

Sitaxsentan in the management of pulmonary arterial hypertension

Author keywords

Binding; Dosage; Drug administration; Drug interactions; Hypertension; Hypotensive agents; Mechanism of action; Pharmacokinetics; Sitaxsentan; Toxicity

Indexed keywords

AMINOTRANSFERASE; ANTICOAGULANT AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; LIVER ENZYME; MITOGENIC AGENT; PLACEBO; SITAXSENTAN;

EID: 33847106052     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.2146/ajhp060357     Document Type: Review
Times cited : (7)

References (23)
  • 1
    • 0023615359 scopus 로고
    • Primary pulmonary hypertension: A national prospective study
    • Rich W, Dantzker DR, Ayres SM et al. Primary pulmonary hypertension: a national prospective study. Ann Intern Med. 1987; 107:216-23.
    • (1987) Ann Intern Med , vol.107 , pp. 216-223
    • Rich, W.1    Dantzker, D.R.2    Ayres, S.M.3
  • 2
    • 1542268243 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension with sildenafil
    • Fung SM, Ferrill MJ. Treatment of pulmonary arterial hypertension with sildenafil. Hosp Pharm. 2004; 39:243-53.
    • (2004) Hosp Pharm , vol.39 , pp. 243-253
    • Fung, S.M.1    Ferrill, M.J.2
  • 3
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension: Results from a national prospective registry
    • D'Alonzo GE, Barst RJ, Ayres SM et al. Survival in patients with primary pulmonary hypertension: results from a national prospective registry. Ann Intern Med. 1991; 115:343-9.
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3
  • 4
    • 3142726157 scopus 로고    scopus 로고
    • Medical therapy for pulmonary arterial hypertension
    • Badesch D, Abman S, Ahearn G et al. Medical therapy for pulmonary arterial hypertension. Chest. 2004; 126:35S-62S.
    • (2004) Chest , vol.126
    • Badesch, D.1    Abman, S.2    Ahearn, G.3
  • 5
    • 33847138203 scopus 로고    scopus 로고
    • bosentan) manufacturer information
    • South San Francisco, CA: Actelion Pharmaceuticals;
    • Tracleer (bosentan) manufacturer information. South San Francisco, CA: Actelion Pharmaceuticals; 2002.
    • (2002)
    • Tracleer1
  • 6
    • 0035818316 scopus 로고    scopus 로고
    • Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: A randomized placebo-controlled study
    • Channick RN, Simonneau G, Sitbon O et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomized placebo-controlled study. Lancet. 2001; 358:1119-23.
    • (2001) Lancet , vol.358 , pp. 1119-1123
    • Channick, R.N.1    Simonneau, G.2    Sitbon, O.3
  • 7
    • 0037149718 scopus 로고    scopus 로고
    • Bosentan therapy for pulmonary arterial hypertension
    • Rubin LJ, Badesch DB, Barst RJ et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med. 2002; 346:896-903.
    • (2002) N Engl J Med , vol.346 , pp. 896-903
    • Rubin, L.J.1    Badesch, D.B.2    Barst, R.J.3
  • 9
    • 3042511852 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension: Future directions report of a National Heart Lung and Blood Institute/Office of Rare Diseases workshop
    • Newman J, Fanburg B, Archer S et al. Pulmonary arterial hypertension: future directions report of a National Heart Lung and Blood Institute/Office of Rare Diseases workshop. Circulation. 2004; 109:2947-52.
    • (2004) Circulation , vol.109 , pp. 2947-2952
    • Newman, J.1    Fanburg, B.2    Archer, S.3
  • 10
    • 0029860546 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of the endothelin-receptor antagonist bosentan in healthy human subjects
    • Weber C, Schmitt R, Birnboeck H et al. Pharmacokinetics and pharmacodynamics of the endothelin-receptor antagonist bosentan in healthy human subjects. Clin Pharmacol Ther. 1996; 60:124-37.
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 124-137
    • Weber, C.1    Schmitt, R.2    Birnboeck, H.3
  • 11
    • 0034720820 scopus 로고    scopus 로고
    • Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure
    • Givertz MM, Colucci WS, LeJemtel TH et al. Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure. Circulation. 2000; 101:2922-7.
    • (2000) Circulation , vol.101 , pp. 2922-2927
    • Givertz, M.M.1    Colucci, W.S.2    LeJemtel, T.H.3
  • 12
    • 0030943903 scopus 로고    scopus 로고
    • Discovery of TBC11251, a potent long acting, orally active endothelin receptor-A selective antagonist
    • Wu C, Chan MF, Stavros F et al. Discovery of TBC11251, a potent long acting, orally active endothelin receptor-A selective antagonist. J Med Chem. 1997; 40:1690-7.
    • (1997) J Med Chem , vol.40 , pp. 1690-1697
    • Wu, C.1    Chan, M.F.2    Stavros, F.3
  • 14
    • 0035040924 scopus 로고    scopus 로고
    • Endothelin system: The double-edged sword in health and disease
    • Kedzierski RM, Yanagisawa M. Endothelin system: the double-edged sword in health and disease. Annu Rev Pharmacol Toxicol. 2001; 41:851-76.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 851-876
    • Kedzierski, R.M.1    Yanagisawa, M.2
  • 15
    • 11144356307 scopus 로고    scopus 로고
    • Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5- ylsulfamoyl)-thiophene-2-carboxamide (TBC3711), a second generation, ETA selective, and orally available endothelin antagonist
    • Wu C, Decker E, Blok N et al. Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5- ylsulfamoyl)-thiophene-2-carboxamide (TBC3711), a second generation, ETA selective, and orally available endothelin antagonist. J Med Chem. 2004; 47:1969-86.
    • (2004) J Med Chem , vol.47 , pp. 1969-1986
    • Wu, C.1    Decker, E.2    Blok, N.3
  • 16
    • 10744230817 scopus 로고    scopus 로고
    • Sitaxsentan therapy for pulmonary arterial hypertension
    • Barst R, Langleben D, Frost A et al. Sitaxsentan therapy for pulmonary arterial hypertension. Am J Resp Crit Care Med. 2004; 169:441-7.
    • (2004) Am J Resp Crit Care Med , vol.169 , pp. 441-447
    • Barst, R.1    Langleben, D.2    Frost, A.3
  • 17
    • 0034720820 scopus 로고    scopus 로고
    • Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure
    • Givertz MM, Colucci WS, LeJemtel TH et al. Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure. Circulation. 2000; 101:2922-7.
    • (2000) Circulation , vol.101 , pp. 2922-2927
    • Givertz, M.M.1    Colucci, W.S.2    LeJemtel, T.H.3
  • 18
    • 0036283401 scopus 로고    scopus 로고
    • Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension
    • Barst RJ, Rich S, Widlitz A et al. Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension. Chest. 2002; 121:1860-8.
    • (2002) Chest , vol.121 , pp. 1860-1868
    • Barst, R.J.1    Rich, S.2    Widlitz, A.3
  • 19
    • 33645074912 scopus 로고    scopus 로고
    • Sitaxsentan: An endothelin-A receptor antagonist for the treatment of pulmonary arterial hypertension
    • O'Callaghan DS, Gaine SP. Sitaxsentan: an endothelin-A receptor antagonist for the treatment of pulmonary arterial hypertension. Int J Clin Pract. 2006; 60:475-81.
    • (2006) Int J Clin Pract , vol.60 , pp. 475-481
    • O'Callaghan, D.S.1    Gaine, S.P.2
  • 20
    • 11144304239 scopus 로고    scopus 로고
    • A receptor antagonist, sitaxsentan sodium, in a patient population with pulmonary arterial hypertension that meets traditional inclusion criteria of previous pulmonary arterial hypertension trials
    • A receptor antagonist, sitaxsentan sodium, in a patient population with pulmonary arterial hypertension that meets traditional inclusion criteria of previous pulmonary arterial hypertension trials. J Cardiovasc Pharmacol. 2004; 44:S80-4.
    • (2004) J Cardiovasc Pharmacol , vol.44
    • Langleben, D.1    Brock, T.2    Barst, R.3
  • 21
    • 33646255654 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension with the selective entothelin-A receptor antagonist sitaxsentan
    • Barst RJ, Langleben D, Badesch D et al. Treatment of pulmonary arterial hypertension with the selective entothelin-A receptor antagonist sitaxsentan. J Am Coll Cardiol. 2006; 47:2049-56.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 2049-2056
    • Barst, R.J.1    Langleben, D.2    Badesch, D.3
  • 22
    • 6344240798 scopus 로고    scopus 로고
    • Sustained symptomatic, functional, and hemodynamic benefit with the selective endothelin-A receptor antagonist, sitaxsentan, in patients with pulmonary arterial hypertension: A 1-year follow-up study
    • Langleben D, Hirsch A, Shalit E et al. Sustained symptomatic, functional, and hemodynamic benefit with the selective endothelin-A receptor antagonist, sitaxsentan, in patients with pulmonary arterial hypertension: a 1-year follow-up study. Chest. 2004; 126:1377-81.
    • (2004) Chest , vol.126 , pp. 1377-1381
    • Langleben, D.1    Hirsch, A.2    Shalit, E.3
  • 23
    • 33645047236 scopus 로고    scopus 로고
    • Warfarin management in pulmonary arterial hypertension is similar between bosentan, placebo, and sitaxsentan
    • Abstract
    • Coyne T, Dixon R. Warfarin management in pulmonary arterial hypertension is similar between bosentan, placebo, and sitaxsentan. Chest. 2005; 128:366S. Abstract.
    • (2005) Chest , vol.128
    • Coyne, T.1    Dixon, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.