Associations of the dopamine D4 receptor gene VNTR polymorphism with drug use in adolescent psychiatric inpatients

Pharmacology Biochemistry and Behavior

Volumn 86, Issue 2, 2007, Pages 401-406

  McGeary, John E ^a,b   Esposito Smythers, Christianne ^b   Spirito, Anthony ^b   Monti, Peter M ^a,b  

^a PROVIDENCE VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Adolescents; DRD4; Substance misuse

Indexed keywords

DOPAMINE 4 RECEPTOR;

ADOLESCENT; ADULT; ARTICLE; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DNA POLYMORPHISM; DRD4 GENE; DRUG ABUSE; FEMALE; GENE; GENETIC LINKAGE; GENOTYPE; HUMAN; IMPULSIVENESS; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; PRIORITY JOURNAL; SUBSTANCE ABUSE; TANDEM REPEAT; VARIABLE NUMBER OF TANDEM REPEAT;

ADOLESCENT; ALCOHOL DRINKING; DATA INTERPRETATION, STATISTICAL; FEMALE; GENOTYPE; HOSPITALS, PSYCHIATRIC; HUMANS; INPATIENTS; INTELLIGENCE TESTS; MALE; MINISATELLITE REPEATS; MOOD DISORDERS; POLYMORPHISM, GENETIC; PSYCHIATRIC STATUS RATING SCALES; QUESTIONNAIRES; RECEPTORS, DOPAMINE D4; RISK; SCHIZOPHRENIA; SUBSTANCE-RELATED DISORDERS;

EID: 33847103653     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2006.11.001     Document Type: Article

References (42)

1. Asghari V., Sanyal S., Buchwaldt S., Paterson A., Jovanovic V., and Van Tol H. Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants. J Neurochem 65 3 (1995) 1157-1165 [Sep]
2. Cantwell D.P., Lewinsohn P.M., Rohde P., and Seeley J.R. Correspondence between adolescent report and parent report of psychiatric diagnostic data. J Am Acad Child Adolesc Psych 36 (1997) 610-619
3. Curtin J.J., Barnett N.P., Colby S.M., Rohsenow D.J., and Monti P.M. Cue reactivity in adolescents: measurement of separate approach and avoidance reactions. J Stud Alcohol 66 3 (2005) 332-343 [May]
4. Czermak C., Lehofer M., Liebmann P.M., and Traynor J. [35S]GTPgammaS binding at the human dopamine D4 receptor variants hD4.2, hD4.4 and hD4.7 following stimulation by dopamine, epinephrine and norepinephrine. Eur J Pharmacol 531 1-3 (2006) 20-24 [Feb 15]
5. Deas D., May M.P., Randall C., Johnson N., and Anton R. Naltrexone treatment of adolescent alcoholics: an open-label pilot study. J Child Adolesc Psychopharmacol 15 5 (2005) 723-728 [Oct]
6. Enoch M.A., and Goldman D. The genetics of alcoholism and alcohol abuse. Curr Psychiatry Rep 3 2 (2001) 144-151 [Apr]
7. Frank Y., Pergolizzi R.G., and Perilla M.J. Dopamine D4 receptor gene and attention deficit hyperactivity disorder. Pediatr Neurol 31 5 (2004) 345-348 [Nov]
8. Freeman B., Powell J., Ball D., Hill L., Craig I., and Plomin R. DNA by mail: an inexpensive and noninvasive method for collecting DNA samples from widely dispersed populations. Behav Genet 27 (1997) 251-257
9. Gottesman I.I., and Gould T.D. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatr 160 4 (2003) 636-645 [Apr]
10. Guo S.W., and Thompson E.A. Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 48 2 (1992) 361-372 [Jun]
11. Harrell A., and Wirtz P.W. Adolescent Drinking Index: Professional Manual (1989), Psychological Assessment Resources, Odessa, FL
12. Harrell A., and Wirtz P. Screening for adolescent problem drinking: validation of a multidimensional instrument for case identification. Psychol Assess 1 (1989) 61-63
13. Harwood HJ, Fountain D, Fountain G. (1992) Economic cost of alcohol and drug abuse in the United States, 1992: a report. Addiction. 1999 May; 94(5):631-5.
14. Heath A.C., Todorov A.A., Nelson E.C., Madden P.A.F., Bucholz K.K., and Martin N.G. Gene-environment interaction effects on behavioral variation and risk of complex disorders: the example of alcoholism and other psychiatric disorders. Twin Res 5 (2002) 30-43
15. Hutchison K.E., LaChance H., Niaura R., Bryan A., and Smolen A. The DRD4 VNTR polymorphism influences reactivity to smoking cues. J Abnorm Psychol 111 1 (2002) 134-143 [Feb]
16. Hutchison K.E., McGeary J., Smolen A., Bryan A., and Swift R.M. The DRD4 VNTR polymorphism moderates craving after alcohol consumption. Health Psychol 21 (2002) 139-146
17. Hutchison K.E., Wooden A., Swift R.M., Smolen A., McGeary J., Adler L., et al. Olanzapine reduces craving for alcohol: a DRD4 VNTR polymorphism by pharmacotherapy interaction. Neuropsychopharmacology 28 (2003) 1882-1888
18. Hutchison K.E., Stallings M., McGeary J., and Bryan A. Population stratification in the candidate gene study: fatal threat or red herring?. Psychol Bull 130 1 (2004) 66-79 [Jan]
19. Kalivas P.W., and Volkow N.D. The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatr 162 8 (2005) 1403-1413 [Aug]
20. Kaufman A.S., and Kaufman N.L. Kaufman Brief Intelligence Test Manual (1990), American Guidance Service, Circle Pines, MN
21. Kaufman J., Birmaher B., Brent D., Rao U., Flynn C., Moreci P., et al. Schedule for affective disorders and schizophrenia for school-age children-present version and lifetime version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psych 36 (1997) 980-988
22. Kendler K.S., Gardner C., Jacobson K.C., Neale M.C., and Prescott C.A. Genetic and environmental influences on illicit drug use and tobacco use across birth cohorts. Psychol Med 35 9 (2005) 1349-1356 [Sep]
23. Klein D.N., Ouimette P.C., Kelly H.S., Ferro T., and Riso L.P. Test-retest reliability team consensus best-estimate diagnoses of Axis I and II disorders in a family study. Am J Psychiatr 151 (1994) 1043-1047
24. Klein D.N., Lewinsohn P.M., Seeley J.R., and Rohde P. A family study of major depressive disorder in a community sample of adolescents. Arch Gen Psychiatry 58 (2001) 13-20
25. Lench N., Stanier P., and Williamson R. Simple non-invasive method to obtain DNA for gene analysis. Lancet 18 (1988) 1356-1358
26. Mackillop J, Menges DP, McGeary JE, Lisman SA. Effects of Craving and DRD4 genotype; under review.
27. McGeary J.E., Hutchison K.E., Darcangelo V., and Feldman J. Minor stressors and the positively reinforcing effects of alcohol [abstract]. Alcohol, Clin Exp Res 25 5 (2001) 135A [June]
28. McGeary J.E., Monti P.M., Rohsenow D.J., Tidey J., and Swift R. The DRD4 gene, drinking and urge to drink after naltrexone: preliminary results from ecological momentary assessment [abstract]. Am J Med Genet (Neuropsychiatric Genetics) 130B 1 (2004) 11.8
29. Miller F.G., and Lazowski L.E. The Adolescent SASSI-A2 Manual: Identifying Substance Use Disorders (2001), The SASSI Institute, Springville, IN
30. Monti P.M., Rohsenow D., Tidey J., McGeary J., and Swift R. Naltrexone, craving for alcohol and drinking: laboratory and ecological assessments [abstract]. Alcohol, Clin Exp Res 28 8 (2004) 65A
31. Needle R., McCubbin H., Lorence J., and Hochhauser M. Reliability and validity of adolescent self-reported drug use in a family based study: a methodological report. Int J Addict 18 (1983) 901-912
32. Oslin D.W., Berrettini W., Kranzler H.R., Pettinati H., Gelernter J., Volpicelli J.R., et al. A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology 28 8 (2003) 1546-1552 [Aug]
33. Rubonis A.V., Colby S.M., Monti P.M., Rohsenow D.J., Gulliver S.B., and Sirota A.D. Alcohol cue reactivity and mood induction in male and female alcoholics. J Stud Alcohol 55 4 (1994) 487-494 [Jul]
34. Sander T., Harms H., Dufeu P., Kuhn S., Rommelspacher H., and Schmidt L.G. Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics. Am J Med Genet 74 (1997) 483-487
35. Shao C., Li Y., Jiang K., Zhang D., Xu Y., Lin L., et al. Dopamine D4 receptor polymorphism modulates cue-elicited heroin craving in Chinese. Psychopharmacology (Berl) 186 2 (2006) 185-190 [Jun]
36. Sinha R., and O'Malley S.S. Craving for alcohol: findings from the clinic and the laboratory. Alcohol Alcohol 34 2 (1999) 223-230 [Mar-Apr]
37. Smolka M.N., McGeary J., Klein S., Bühler M., Leménager T., Schumann G., et al. DRD4 VNTR polymorphism moderates fMRI BOLD response to alcohol-related stimuli [abstract]. Alcohol Alcohol 40 Suppl 1 (2005) i27 [September]
38. Sobik L., Hutchison K., and Craighead L. Cue-elicited craving for food: a fresh approach to the study of binge eating. Appetite 44 3 (2005) 253-261 [Jun]
39. Spreen O., and Strauss E. A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary (1998), Oxford University Press, NY
40. Winters K.C. Development of an adolescent alcohol and other drug abuse screening scale: Personal Experience Screening Questionnaire. Addict Behav 17 (1992) 479-490
41. Zalsman G., Frisch A., Lewis R., Michaelovsky E., Hermesh H., Sher L., et al. DRD4 receptor gene exon III polymorphism in inpatient suicidal adolescents. J Neural Transm 111 12 (2004) 1593-1603 [Dec]
42. Zinser M.C., Baker T.B., Sherman J.E., and Cannon D.S. Relation between self-reported affect and drug urges and cravings in continuing and withdrawing smokers. J Abnorm Psychol 101 4 (1992) 617-629 [Nov]