Tropomodulin expression in developing hearts of normal and cardiac mutant Mexican axolotl

Cardiovascular Toxicology

Volumn 6, Issue 2, 2006, Pages 85-98

  McLean, Matthew D ^a   Zajdel, Robert W ^a   Dube, Syamalima ^a   Thurston, Harold ^a   Dube, Dipak K ^a,b  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b Department of Medicine ^*  (United States)

Author keywords

Ambystoma mexicanum; Tropomodulin

Indexed keywords

MUSCLE PROTEIN; PROTEIN ANTIBODY; TROPOMODULIN;

AMBYSTOMA; ANIMAL TISSUE; ARTICLE; EMBRYO; HEART DEVELOPMENT; IMMUNOLOCALIZATION; LETHAL MUTANT; MUSCLE FIBRIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; THIN FILAMENT;

AMBYSTOMA; ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; BLOTTING, WESTERN; ERYTHROCYTES; GENES, LETHAL; HEART; IMMUNOHISTOCHEMISTRY; MICROSCOPY, CONFOCAL; MUTATION; MYOCARDIUM; MYOFIBRILS; TROPOMODULIN;

AMBYSTOMA MEXICANUM; AMPHIBIA; ANIMALIA;

EID: 33847095880     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1385/CT:6:2:85     Document Type: Article

References (39)

1. Humphrey, R.R. (1972). Genetic and experimental studies on a mutant gene (c) determining absence of heart action in embryos of the Mexican axolotl (Ambystoma mexicanum). Dev. Biol. 27:365-375.
2. Lemanski, L.F. (1973). Morphology of developing heart in cardiac lethal mutant Mexican axolotls, Ambystoma mexicanum. Dev. Biol. 33:312-333.
3. Towbin, J.A. and Bowles, N.E. (2002). Cardiomyopathies and myofibril abnormalities, in Myofibrillogenesis (D.K. Dube, ed.). Birkhauser, Boston: pp. 237-264.
4. Sussman, M.A., Hamm-Alvarez, S.F., Vilalta, P.M., Welch, S., and Kedes, L. (1997). Involvement of phosphorylation in doxorubicin-mediated myofibril degeneration: an immunoflourescence microscopic analysis. Circ Res. 80:52-61.
5. Fowler, V.M., Greenfield, N.J., and Moyer, J. (2003). Tropomodulin contains two actin filament pointed end-capping domains. J. Biol.Chem. 278:40,000-40,009.
6. Fritz-Six, K.L., Cox, P.R., Xu, B., Gregorio, C.C., Zoghi, H.Y., and Fowler, V.M. (2003). Aberrant myofibril assembly in tropomodulin 1 null mice leads to aborted heart development and embryonic lethality. J. Cell. Biol. 163:1033-1044.
7. Ehler, E., Fowler, V.M., and Perriard, J-C. (2004). Myofibrillogenesis in the developing chicken heart: Role of actin isoforms and of the pointed end actin capping protein tropomodulin during thin filament assembly. Dev. Dyn. 229:745-755.
8. Fowler, V.M. (1990). Tropomodulin: a cytoskeletal protein that binds to the end of erythrocyte tropomyosin and inhibits tropomyosin binding to actin. J. Cell Biol. 111:471-481.
9. Gregorio, C.C., Weber, A., Bondad, M., Pennise, C.R., and Fowler, V.M. (1995). Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic chick cardiac myocytes. Nature 377:83-86.
10. Sussman, M.A., Ito, M., Daniels, M.P., Flucher, B., Buranen, S., and Kedes, L. (1996). Chicken skeletal muscle tropomodulin: novel localization and characterization. Cell Tissue Res. 285:287-296.
11. Weber, A., Pennise, C.R., Babcock, G.G., and Fowler, V.M. (1994). Tropomodulin caps the pointed ends of actin filaments [see comments]. J. Cell Biol. 127:1627-1635.
12. Sussman, M.A., Baque, S., Uhm, C.S., et al. (1998). Altered expression of tropomodulin in cardiomyocytes disrupts the sarcomeric structure of myofibrils. Circ. Res. 82:94-105.
13. Sussman, M.A., Welch, S., Cambon, N., et al. (1998). Myofibril degeneration caused by tropomodulin overexpression leads to dilated cardiomyopathy in juvenile mice. J. Clin. Invest. 101:51-61.
14. Dye, C.A., Lee, J.K., Atkinson, R.C., Brewster, R., Han, P.L., and Bellen, H.J. (1998). The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein. Development 125:1845-1856.
15. Skeath, J.B. and. Doe, C.Q. (1998). Sanpodo and Notch act in opposition to Numb to distinguish sibling neuron fates in the Drosophila CNS. Development 125:1857-1865.
16. Kong, K.Y. and Kedes, L. (2006). Leucine-135 of tropomodulin-1 regulates its association with tropomyosin, its celular localization and the integrity of sarcomeres. J. Biol. Chem. 281:9589-9599.
17. Humphrey, R.R. (1968). A genetically determined absence of heart function in embryos of the Mexican axolotl (Ambystoma mexicanum). Anat. Rec. 162:475.
18. Smith, S.C. and Armstrong, J.B. (1990). Heart Induction in wild-type and cardiac mutant axolotl (Ambystoma mexicanum). J. Exp. Zool. 254:48-54.
19. Smith, S.C. and Armstrong, J.B. (1991). Heart development in normal and cardiac-lethal mutant axolotls: a model for the control of vertebrate cardiogenesis. Differentiation 47:129-134.
20. Zajdel, R.W., McLean, M.D., Lemanski, S.L., et al. (1998). Ectopic expression of tropomyosin promotes myofibrillogenesis in mutant axolotl hearts. Dev. Dyn. 213:412-420.
21. Zajdel, R.W., Denz, C.R., McLean, M.D., et al. (2005). Diminished myofibril organization in mutant axolotl hearts transfected with site-directed mutants of sarcomeric tropomyosins. Card. Vascular Toxicol. 5:75-90.
22. Bordzilovskaya, N., Detlaff T.A., Duhon S., and Malacinski, G.M. (1989). Developmental-stage series of axolotl embryos, in Developmental Biology of the Axolotl (J.B. Armstrong and G.M. Malacinski, ed.). Oxford University Press, NY: pp. 201-221.
23. Ward, S.M., Dube, D.K., Fransen, M.E., and Lemanski, L.F. (1996). Differential expression of C-protein isoforms in the developing heart of normal and cardiac lethal mutant axolotls (Ambystoma mexicanum). Dev. Dyn. 205:93-103.
24. Bell, P., Rundquist, I., Svensson, I., and Collins, V.P. (1987). Use of cytofluorotomy to evaluate binding of antibodies to the cytoskeleton of cultured cells. J. Histochem. Cytochem. 35:1381-1388.
25. Dube, D.K., Parker, J.D., French, D.C., et al. (1991). Artificial mutants generated by the insertion of random oligonucleotides into the putative nucleoside binding site of the HSV-1 thymidine kinase gene. Biochemistry 30:11,760-11,767.
26. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
27. Rhee, D., Sanger, J.M., and Sanger, J.W. (1994). The premyofibril: evidence for its role in myofibrillogenesis. Cell Motil. Cytoskeleton 28:1-24.
28. Schultheiss, T., Lin, Z.X., Lu, M.H., et al. (1990). Differential distribution of subsets of myofibrillar proteins in cardiac nonstriated and striated myofibrils. J. Cell Biol. 110:1159-1172.
29. Fransen, M.E. and Lemanski, L.F. (1988). Myocardial cell relationships during morphogenesis in normal and cardiac lethal mutant axolotls, Ambystoma mexicanum. Am. J. Anat. 183:245-257.
30. Fransen, M.E. and Lemanski, L.F. (1991). Extracellular matrix of the developing heart in normal and cardiac lethal mutant axolotls, Ambystoma mexicanum. Anat. Rec. 230:387-405.
31. Turnacioglu, K.K., Mittal, B., Dabiri, G.A., Sanger, J.M., and Sanger, J.W. (1997). Zeugmatin is part of the Z-band targeting region of titin. Cell Struct. Funct. 22:73-82.
32. Fowler, V.M. (1997). Capping actin filament growth: tropomodulin in muscle and nonmuscle cells. Soc. Gen. Physiol. Ser. 52:79-89.
33. Ito, M., Swanson, B., Sussman, M.A., Kedes, L., and Lyons, G. (1995). Cloning of tropomodulin cDNA and localization of gene transcripts during mouse embryogenesis. Dev. Biol. 167:317-328.
34. Gregorio, C.C. and Fowler, V.M. (1995). Mechanisms of thin filament assembly in embryonic chick cardiac myocytes: tropomodulin requires tropomyosin for assembly. J. Cell Biol. 129:683-695.
35. Linask, K.K. and Lash, J.W. (1998). Morphoregulatory mechanisms underlying early heart development: precardiac stages to the looping, tubular heart, in Living Morphogenesis of the Heart (M.V. de la Cruz and R.B. Markwald, eds.). Birkhauser, Boston: pp. 1-42.
36. La France, S. and Lemanski, L.F. 1994. Immunofluorescent confocal analysis of tropomyosin in developing hearts of normal and cardiac mutant axolotls, Ambystoma mexicanum. Int. J. Dev. Biol. 38:695-700.
37. Ehler, E., Rothen, B.M., Hämmerle, S.P., Komiyama, M., and Perriard, J-C. (1999). Myofibrillogenesis in the developing chicken heart: assembly of Z-disk, M-line and the thick filaments. J. Cell. Sci. 112:1529-1539.
38. Aeurbach, D., Rothen-Ruthishauser, B., Bantle, S., et al. (1997). Molecular mechanisms of myofibril assembly in heart. Cell. Struct. Funct. 22:139-146.
39. Turnacioglu, K.K., Mittal, B., Dabiri, G.A., Sanger, J.M., and Sanger, J.W. (1997). An N-terminal fragment of titin coupled to green fluorescent protein localizes to the Z-bands in living muscle cells: overexpression leads to myofibril disassembly. Mol. Biol. Cell. 8:705-717.