메뉴 건너뛰기




Volumn 117, Issue 2, 2007, Pages 83-90

Changes in expression of apoptosis-related genes are linked to the molecular response to imatinib treatment in chronic-phase chronic myeloid leukemia patients

Author keywords

Apoptosis; BAD; BAX; BCL XL; BCL XS; BCL2; BCR ABL; Chronic myelogenous leukemia; Imatinib

Indexed keywords

HEMOGLOBIN; IMATINIB; MESSENGER RNA;

EID: 33847084601     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000096858     Document Type: Article
Times cited : (3)

References (35)
  • 1
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo TG, Pendergast AM, Muller AJ, Witte ON: Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 1990;247:1079-1082.
    • (1990) Science , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 4
    • 0036547417 scopus 로고    scopus 로고
    • Death and antideath: Tumour resistance to apoptosis
    • Igney FH, Krammer PH: Death and antideath: tumour resistance to apoptosis. Nat Rev Cancer 2002;2:277-288.
    • (2002) Nat Rev Cancer , vol.2 , pp. 277-288
    • Igney, F.H.1    Krammer, P.H.2
  • 5
    • 0034689031 scopus 로고    scopus 로고
    • Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL
    • Horita M, Andreu EJ, Benito A, Arbona C, Sanz C, Benet I, Prosper F, Fernandez-Luna JL: Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL. J Exp Med 2000;191:977-984.
    • (2000) J Exp Med , vol.191 , pp. 977-984
    • Horita, M.1    Andreu, E.J.2    Benito, A.3    Arbona, C.4    Sanz, C.5    Benet, I.6    Prosper, F.7    Fernandez-Luna, J.L.8
  • 6
    • 0033959620 scopus 로고    scopus 로고
    • The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: Roles for phosphatidylinositol 3-kinase and Raf
    • Neshat MS, Raitano AB, Wang HG, Reed JC, Sawyers CL: The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf. Mol Cell Biol 2000;20:1179-1186.
    • (2000) Mol Cell Biol , vol.20 , pp. 1179-1186
    • Neshat, M.S.1    Raitano, A.B.2    Wang, H.G.3    Reed, J.C.4    Sawyers, C.L.5
  • 7
    • 0036090222 scopus 로고    scopus 로고
    • Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro
    • Graham SM, Jorgensen HG, Allan E, Pearson C, Alcorn MJ, Richmond L, Holyoake TL: Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. Blood 2002;99:319-325.
    • (2002) Blood , vol.99 , pp. 319-325
    • Graham, S.M.1    Jorgensen, H.G.2    Allan, E.3    Pearson, C.4    Alcorn, M.J.5    Richmond, L.6    Holyoake, T.L.7
  • 8
    • 0038264431 scopus 로고    scopus 로고
    • Cell context-specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors
    • Wong S, McLaughlin J, Cheng D, Witte ON: Cell context-specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors. Blood 2003;101:4088-4097.
    • (2003) Blood , vol.101 , pp. 4088-4097
    • Wong, S.1    McLaughlin, J.2    Cheng, D.3    Witte, O.N.4
  • 10
    • 0031950324 scopus 로고    scopus 로고
    • Conversion of interferon-induced, longterm cytogenetic remissions in chronic myelogenous leukemia to polymerase chain reaction negativity
    • Kurzrock R, Estrov Z, Kantarjian H, Talpaz M: Conversion of interferon-induced, longterm cytogenetic remissions in chronic myelogenous leukemia to polymerase chain reaction negativity. J Clin Oncol 1998;16:1526-1531.
    • (1998) J Clin Oncol , vol.16 , pp. 1526-1531
    • Kurzrock, R.1    Estrov, Z.2    Kantarjian, H.3    Talpaz, M.4
  • 11
    • 18744419356 scopus 로고    scopus 로고
    • Molecular heterogeneity in complete cytogenetic responders after interferon-alpha therapy for chronic myelogenous leukemia: Low levels of minimal residual disease are associated with continuing remission. German CML Study Group and the UK MRC CML Study Group
    • Hochhaus A, Reiter A, Saussele S, Reichert A, Emig M, Kaeda J, Schultheis B, Berger U, Shepherd PC, Allan NC, Hehlmann R, Goldman JM, Cross NC: Molecular heterogeneity in complete cytogenetic responders after interferon-alpha therapy for chronic myelogenous leukemia: low levels of minimal residual disease are associated with continuing remission. German CML Study Group and the UK MRC CML Study Group. Blood 2000;95:62-66.
    • (2000) Blood , vol.95 , pp. 62-66
    • Hochhaus, A.1    Reiter, A.2    Saussele, S.3    Reichert, A.4    Emig, M.5    Kaeda, J.6    Schultheis, B.7    Berger, U.8    Shepherd, P.C.9    Allan, N.C.10    Hehlmann, R.11    Goldman, J.M.12    Cross, N.C.13
  • 14
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993;74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 15
    • 0029024368 scopus 로고
    • Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta
    • Apte SS, Mattei MG, Olsen BR: Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta. Genomics 1995;26:592-594.
    • (1995) Genomics , vol.26 , pp. 592-594
    • Apte, S.S.1    Mattei, M.G.2    Olsen, B.R.3
  • 17
    • 0029874986 scopus 로고    scopus 로고
    • Bcl-x(S) antagonizes the protective effects of Bcl-x(L)
    • Minn AJ, Boise LH, Thompson CB: Bcl-x(S) antagonizes the protective effects of Bcl-x(L). J Biol Chem 1996;271:6306-6312.
    • (1996) J Biol Chem , vol.271 , pp. 6306-6312
    • Minn, A.J.1    Boise, L.H.2    Thompson, C.B.3
  • 18
    • 0033775615 scopus 로고    scopus 로고
    • Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
    • Bustin SA: Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol 2000;25:169-193.
    • (2000) J Mol Endocrinol , vol.25 , pp. 169-193
    • Bustin, S.A.1
  • 20
    • 0029015690 scopus 로고
    • Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2
    • Sanchez-Garcia I, Grutz G: Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2. Proc Natl Acad Sci USA 1995;92:5287-5291.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5287-5291
    • Sanchez-Garcia, I.1    Grutz, G.2
  • 21
    • 0037464449 scopus 로고    scopus 로고
    • Comparison of the anti-apoptotic effects of Bcr-Abl, Bcl-2 and Bcl-x(L) following diverse apoptogenic stimuli
    • Brumatti G, Weinlich R, Chehab CF, Yon M, Amarante-Mendes GP: Comparison of the anti-apoptotic effects of Bcr-Abl, Bcl-2 and Bcl-x(L) following diverse apoptogenic stimuli. FEBS Lett 2003;541:57-63.
    • (2003) FEBS Lett , vol.541 , pp. 57-63
    • Brumatti, G.1    Weinlich, R.2    Chehab, C.F.3    Yon, M.4    Amarante-Mendes, G.P.5
  • 25
    • 0023270373 scopus 로고
    • Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia
    • Gordon MY, Dowding CR, Riley GP, Goldman JM, Greaves MF: Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia. Nature 1987;328:342-344.
    • (1987) Nature , vol.328 , pp. 342-344
    • Gordon, M.Y.1    Dowding, C.R.2    Riley, G.P.3    Goldman, J.M.4    Greaves, M.F.5
  • 26
    • 0034653929 scopus 로고    scopus 로고
    • STAT5 activation contributes to growth and viability in Bcr/Abl-transformed cells
    • Sillaber C, Gesbert F, Frank DA, Sattler M, Griffin JD: STAT5 activation contributes to growth and viability in Bcr/Abl-transformed cells. Blood 2000;95:2118-2125.
    • (2000) Blood , vol.95 , pp. 2118-2125
    • Sillaber, C.1    Gesbert, F.2    Frank, D.A.3    Sattler, M.4    Griffin, J.D.5
  • 29
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S: Tumour stem cells and drug resistance. Nat Rev Cancer 2005;5:275-284.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 30
    • 0038454621 scopus 로고    scopus 로고
    • Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment
    • Bhatia R, Holtz M, Niu N, Gray R, Snyder DS, Sawyers CL, Arber DA, Slovak ML, Forman SJ: Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment. Blood 2003;101:4701-4707.
    • (2003) Blood , vol.101 , pp. 4701-4707
    • Bhatia, R.1    Holtz, M.2    Niu, N.3    Gray, R.4    Snyder, D.S.5    Sawyers, C.L.6    Arber, D.A.7    Slovak, M.L.8    Forman, S.J.9
  • 31
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G: The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 1997;3:614-620.
    • (1997) Nat Med , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 32
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams JM, Cory S: The Bcl-2 protein family: arbiters of cell survival. Science 1998;281:1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 33
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the BCL2 family and cell death
    • Yang E, Korsmeyer SJ: Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 1996;88:386-401.
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsmeyer, S.J.2
  • 34
    • 0030959304 scopus 로고    scopus 로고
    • Bcl-2 phosphorylation required for anti-apoptosis function
    • Ito T, Deng X, Carr B, May WS: Bcl-2 phosphorylation required for anti-apoptosis function. J Biol Chem 1997;272:11671-11673.
    • (1997) J Biol Chem , vol.272 , pp. 11671-11673
    • Ito, T.1    Deng, X.2    Carr, B.3    May, W.S.4
  • 35
    • 1842333237 scopus 로고    scopus 로고
    • del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G: Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997;278:687-689.
    • del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G: Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997;278:687-689.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.