메뉴 건너뛰기




Volumn 26, Issue 1, 2005, Pages 85-91

Signal pathways underlying homocysteine-induced production of MCP-1 and 1L-8 in cultured human whole blood

Author keywords

Calmodulin; Homocysteine; Interleukin 8; Mitogen activated protein kinases; Monocyte chemoattractant protein 1; NF B; Protein kinase C; Protein tyrosine kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALMODULIN; CALPHOSTIN C; CIGLITAZONE; CURCUMIN; CYSTEINE; GENISTEIN; HOMOCYSTEINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; METHIONINE; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; PYRROLIDINE DITHIOCARBAMATE; TROGLITAZONE; TYRPHOSTIN;

EID: 11844253838     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2005.00005.x     Document Type: Article
Times cited : (23)

References (38)
  • 1
    • 8644239394 scopus 로고    scopus 로고
    • Homocysteine induces production of monocyte chemoattractant protein-1 and interleukin-8 in cultured human whole blood
    • Zeng X, Remick DG, Wang X. Homocysteine induces production of monocyte chemoattractant protein-1 and interleukin-8 in cultured human whole blood. Acta Pharmacol Sin 2004; 25; 1419-25.
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 1419-1425
    • Zeng, X.1    Remick, D.G.2    Wang, X.3
  • 2
    • 0032760728 scopus 로고    scopus 로고
    • Chemokines and atherosclerosis
    • Reape TJ, Groot P. Chemokines and atherosclerosis. Atherosclerosis 1999; 147: 213-5.
    • (1999) Atherosclerosis , vol.147 , pp. 213-215
    • Reape, T.J.1    Groot, P.2
  • 3
    • 0037432168 scopus 로고    scopus 로고
    • Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes
    • de Lemos JA, Morrow DA, Sabatine MS, Murphy SA, Gibson CM, Antman EM, et al. Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes. Circulation 2003; 107: 690-5.
    • (2003) Circulation , vol.107 , pp. 690-695
    • De Lemos, J.A.1    Morrow, D.A.2    Sabatine, M.S.3    Murphy, S.A.4    Gibson, C.M.5    Antman, E.M.6
  • 6
    • 0036164560 scopus 로고    scopus 로고
    • Interleukin 8 and venous thrombosis: Evidence for a role of inflammation in thrombosis
    • Van Aken BE, Reitsma PH, Rosendaal FR. Interleukin 8 and venous thrombosis: evidence for a role of inflammation in thrombosis. Br J Haematol 2002; 116: 173-7.
    • (2002) Br J Haematol , vol.116 , pp. 173-177
    • Van Aken, B.E.1    Reitsma, P.H.2    Rosendaal, F.R.3
  • 7
    • 0242486705 scopus 로고    scopus 로고
    • Homocysteine, cysteine, and glutathione in human colonic mucosa: Elevated levels of homocysteine in patients with inflammatory bowel disease
    • Morgenstern I, Raijmakers MT, Peters WH, Hoensch H, Kirch W. Homocysteine, cysteine, and glutathione in human colonic mucosa: elevated levels of homocysteine in patients with inflammatory bowel disease. Dig Dis Sci 2003; 48: 2083-90.
    • (2003) Dig Dis Sci , vol.48 , pp. 2083-2090
    • Morgenstern, I.1    Raijmakers, M.T.2    Peters, W.H.3    Hoensch, H.4    Kirch, W.5
  • 8
    • 10744224347 scopus 로고    scopus 로고
    • Homocysteine in patients with rheumatoid arthritis in relation to inflammation and B-vitamin treatment
    • Yxfeldt A, Wallberg-Jonsson S, Hultdin J, Rantapaa-Dahlqvist S. Homocysteine in patients with rheumatoid arthritis in relation to inflammation and B-vitamin treatment. Scand J Rheumatol 2003; 32: 205-10.
    • (2003) Scand J Rheumatol , vol.32 , pp. 205-210
    • Yxfeldt, A.1    Wallberg-Jonsson, S.2    Hultdin, J.3    Rantapaa-Dahlqvist, S.4
  • 9
    • 0037645942 scopus 로고    scopus 로고
    • Increased plasma homocysteine levels without signs of vitamin B12 deficiency in patients with multiple sclerosis assessed by blood and cerebrospinal fluid homocysteine and methylmalonic acid
    • Vrethem M, Mattsson E, Hebelka H, Leerbeck K, Osterberg A, Landtblom AM, et al. Increased plasma homocysteine levels without signs of vitamin B12 deficiency in patients with multiple sclerosis assessed by blood and cerebrospinal fluid homocysteine and methylmalonic acid. Mult Scler 2003; 9: 239-45.
    • (2003) Mult Scler , vol.9 , pp. 239-245
    • Vrethem, M.1    Mattsson, E.2    Hebelka, H.3    Leerbeck, K.4    Osterberg, A.5    Landtblom, A.M.6
  • 10
    • 0037532658 scopus 로고    scopus 로고
    • Reduction in plasma homocysteine level in patients with rheumatoid arthritis given pulsed glucocorticoid treatment
    • Lazzerini PE, Capecchi PL, Bisogno S, Galeazzi M, Marcolongo R, Pasini FL. Reduction in plasma homocysteine level in patients with rheumatoid arthritis given pulsed glucocorticoid treatment. Ann Rheum Dis 2003; 62: 694-5.
    • (2003) Ann Rheum Dis , vol.62 , pp. 694-695
    • Lazzerini, P.E.1    Capecchi, P.L.2    Bisogno, S.3    Galeazzi, M.4    Marcolongo, R.5    Pasini, F.L.6
  • 12
    • 0037297716 scopus 로고    scopus 로고
    • The methionine-homocysteine cycle and its effects on cognitive diseases
    • Miller AL. The methionine-homocysteine cycle and its effects on cognitive diseases. Altern Med Rev 2003; 8: 7-19.
    • (2003) Altern Med Rev , vol.8 , pp. 7-19
    • Miller, A.L.1
  • 13
    • 0036398629 scopus 로고    scopus 로고
    • Hyperhomocysteinemia: A new risk factor for degenerative diseases
    • Hermann W, Knapp JP. Hyperhomocysteinemia: a new risk factor for degenerative diseases. Clin Lab 2002; 48: 471-81.
    • (2002) Clin Lab , vol.48 , pp. 471-481
    • Hermann, W.1    Knapp, J.P.2
  • 14
    • 0027949106 scopus 로고
    • Role of protein kinase pathways in IL-1-induced chemoattractant expression by human mesangial cells
    • Rovin BH, Tan LC. Role of protein kinase pathways in IL-1-induced chemoattractant expression by human mesangial cells. Kidney Int 1994; 46: 1059-68.
    • (1994) Kidney Int , vol.46 , pp. 1059-1068
    • Rovin, B.H.1    Tan, L.C.2
  • 15
    • 0033192573 scopus 로고    scopus 로고
    • Oxidant stress regulation of IL-8 and ICAM-1 gene expression: Differential activation and binding of the transcription factors AP-1 and NF-kappaB
    • Roebuck KA. Oxidant stress regulation of IL-8 and ICAM-1 gene expression: differential activation and binding of the transcription factors AP-1 and NF-kappaB (Review). Int J Mol Med 1999; 4: 223-30.
    • (1999) Int J Mol Med , vol.4 , pp. 223-230
    • Roebuck, K.A.1
  • 16
    • 0038015256 scopus 로고    scopus 로고
    • Differential effects of staurosporine and its analogues on chemokine release by promyelocytic leukemia cell line NB-4
    • Steube KG, Meyer C, Schupp P, Proksch P, Drexler HG. Differential effects of staurosporine and its analogues on chemokine release by promyelocytic leukemia cell line NB-4. Leuk Res 2003; 27: 957-63.
    • (2003) Leuk Res , vol.27 , pp. 957-963
    • Steube, K.G.1    Meyer, C.2    Schupp, P.3    Proksch, P.4    Drexler, H.G.5
  • 17
    • 0034772002 scopus 로고    scopus 로고
    • Effect of homocysteine on murine splenic B lymphocyte proliferation and its signal transduction mechanism
    • Zhang Q, Zeng X, Guo J, Wang X. Effect of homocysteine on murine splenic B lymphocyte proliferation and its signal transduction mechanism. Cardiovasc Res 2001; 52: 328-36.
    • (2001) Cardiovasc Res , vol.52 , pp. 328-336
    • Zhang, Q.1    Zeng, X.2    Guo, J.3    Wang, X.4
  • 18
    • 0036197073 scopus 로고    scopus 로고
    • Oxidant stress mechanism of homocysteine potentiating ConA-induced proliferation in murine T lymphocytes
    • Zhang Q, Zeng X, Guo J, Wang X. Oxidant stress mechanism of homocysteine potentiating ConA-induced proliferation in murine T lymphocytes. Cardiovasc Res 2002; 53:1035-42.
    • (2002) Cardiovasc Res , vol.53 , pp. 1035-1042
    • Zhang, Q.1    Zeng, X.2    Guo, J.3    Wang, X.4
  • 19
    • 0034525917 scopus 로고    scopus 로고
    • T cell signaling and autoimmune diabetes. T cell signaling and autoimmune diabetes
    • Buchs AE, Rapoport MJ. T cell signaling and autoimmune diabetes. T cell signaling and autoimmune diabetes. J Pediatr Endocrinol Metab 2000; 13: 1549-54.
    • (2000) J Pediatr Endocrinol Metab , vol.13 , pp. 1549-1554
    • Buchs, A.E.1    Rapoport, M.J.2
  • 20
    • 0038785843 scopus 로고    scopus 로고
    • Molecular targets of lead in brain neurotoxicity
    • Marchetti C. Molecular targets of lead in brain neurotoxicity. Neurotox Res 2003; 5: 221-36.
    • (2003) Neurotox Res , vol.5 , pp. 221-236
    • Marchetti, C.1
  • 21
    • 0035376828 scopus 로고    scopus 로고
    • Intracellular signaling pathways as a target for the treatment of rheumatoid arthritis
    • Kumar S, Blake SM, Emery JG. Intracellular signaling pathways as a target for the treatment of rheumatoid arthritis. Curr Opin Pharmacol 2001; 1: 307-13.
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 307-313
    • Kumar, S.1    Blake, S.M.2    Emery, J.G.3
  • 22
    • 0036241265 scopus 로고    scopus 로고
    • Newer immunosuppressive drugs: Their potential role in rheumatoid arthritis therapy
    • Drosos AA. Newer immunosuppressive drugs: their potential role in rheumatoid arthritis therapy. Drugs 2002; 62: 891-907.
    • (2002) Drugs , vol.62 , pp. 891-907
    • Drosos, A.A.1
  • 23
    • 0026607996 scopus 로고
    • Biphasic production of IL-8 in lipopolysaccharide (LPS)-stimulated human whole blood. Separation of LPS- And cytokine-stimulated components using anti-tumor necrosis factor and anti-IL-1 antibodies
    • DeForge LE, Kenney JS, Jones ML, Warren JS, Remick DG. Biphasic production of IL-8 in lipopolysaccharide (LPS)-stimulated human whole blood. Separation of LPS- and cytokine-stimulated components using anti-tumor necrosis factor and anti-IL-1 antibodies. J Immunol 1992; 148: 2133-41.
    • (1992) J Immunol , vol.148 , pp. 2133-2141
    • DeForge, L.E.1    Kenney, J.S.2    Jones, M.L.3    Warren, J.S.4    Remick, D.G.5
  • 24
    • 0026490802 scopus 로고
    • Oxygen radical scavengers selectively inhibit interleukin 8 production in human whole blood
    • DeForge LE, Fantone JC, Kenney JS, Remick DG. Oxygen radical scavengers selectively inhibit interleukin 8 production in human whole blood. J Clin Invest 1992; 90: 2123-9.
    • (1992) J Clin Invest , vol.90 , pp. 2123-2129
    • DeForge, L.E.1    Fantone, J.C.2    Kenney, J.S.3    Remick, D.G.4
  • 25
    • 0035122305 scopus 로고    scopus 로고
    • Homocysteine stimulates the expression of monocyte chemoattractant protein-1 in endothelial cells leading to enhanced monocyte chemotaxis
    • Sung FL, Slow YL, Wang G, Lynn EG, O K. Homocysteine stimulates the expression of monocyte chemoattractant protein-1 in endothelial cells leading to enhanced monocyte chemotaxis. Mol Cell Biochem 2001; 216: 121-8.
    • (2001) Mol Cell Biochem , vol.216 , pp. 121-128
    • Sung, F.L.1    Slow, Y.L.2    Wang, G.3    Lynn, E.G.4    O., K.5
  • 26
    • 0034671604 scopus 로고    scopus 로고
    • Homocysteine stimulates nuclear factor kappaB activity and monocyte chemoattractant protein-1 expression in vascular smooth-muscle cells: A possible role for protein kinase C
    • Wang G, Siow YL, O K. Homocysteine stimulates nuclear factor kappaB activity and monocyte chemoattractant protein-1 expression in vascular smooth-muscle cells: a possible role for protein kinase C. Biochem J 2000; 352: 817-26.
    • (2000) Biochem J , vol.352 , pp. 817-826
    • Wang, G.1    Siow, Y.L.2    O., K.3
  • 27
    • 0037016548 scopus 로고    scopus 로고
    • Hydrogen peroxide induced chemokine production in the glia-rich cultured cerebellar granule cells under acidosis
    • Miura I, Miyamoto K, Nakamura K, Watanabe Y. Hydrogen peroxide induced chemokine production in the glia-rich cultured cerebellar granule cells under acidosis. Life Sci 2002; 70: 821-31.
    • (2002) Life Sci , vol.70 , pp. 821-831
    • Miura, I.1    Miyamoto, K.2    Nakamura, K.3    Watanabe, Y.4
  • 28
    • 0035028411 scopus 로고    scopus 로고
    • Calcium-dependent interleukin-8 gene expression in T84 human colonie epithelial cells
    • Yu Y, De Waele C, Chadee K. Calcium-dependent interleukin-8 gene expression in T84 human colonie epithelial cells. Inflamm Res 50: 220-6.
    • Inflamm Res , vol.50 , pp. 220-226
    • Yu, Y.1    De Waele, C.2    Chadee, K.3
  • 29
    • 0034839031 scopus 로고    scopus 로고
    • Impact of cell swelling on proliferative signal transduction in the liver
    • Kim RD, Stein GS, Chari RS. Impact of cell swelling on proliferative signal transduction in the liver. J Cell Biochem 2001; 83: 56-69.
    • (2001) J Cell Biochem , vol.83 , pp. 56-69
    • Kim, R.D.1    Stein, G.S.2    Chari, R.S.3
  • 30
    • 0035005115 scopus 로고    scopus 로고
    • Signaling pathways for glycated human serum albumin-induced IL-8 and MCP-1 secretion in human RPE cells
    • Bian ZM, Einer VM, Yoshida A, Kunkel SL, Einer SG. Signaling pathways for glycated human serum albumin-induced IL-8 and MCP-1 secretion in human RPE cells. Invest Ophthalmol Vis Sci 2001; 42: 1660-8.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 1660-1668
    • Bian, Z.M.1    Einer, V.M.2    Yoshida, A.3    Kunkel, S.L.4    Einer, S.G.5
  • 31
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb MH, Goldsmith EJ. How MAP kinases are regulated. J Biol Chem 1995; 270: 14843-6.
    • (1995) J Biol Chem , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 32
    • 0034885358 scopus 로고    scopus 로고
    • New insights into the role of nuclear factor-kappaB in cell growth regulation
    • Chen F, Castranova V, Shi X. New insights into the role of nuclear factor-kappaB in cell growth regulation. Am J Pathol 2001; 159: 387-97.
    • (2001) Am J Pathol , vol.159 , pp. 387-397
    • Chen, F.1    Castranova, V.2    Shi, X.3
  • 33
    • 18744414483 scopus 로고    scopus 로고
    • Shiga toxin-2 triggers endothelial leukocyte adhesion and transmigration via NF-kappaB dependent up-regulation of IL-8 and MCP-1
    • Zoja C, Angioletti S, Donadelli R, Zanchi C, Tomasoni S, Binda E, et al. Shiga toxin-2 triggers endothelial leukocyte adhesion and transmigration via NF-kappaB dependent up-regulation of IL-8 and MCP-1. Kidney Int 2002; 62: 846-56.
    • (2002) Kidney Int , vol.62 , pp. 846-856
    • Zoja, C.1    Angioletti, S.2    Donadelli, R.3    Zanchi, C.4    Tomasoni, S.5    Binda, E.6
  • 34
    • 0032475922 scopus 로고    scopus 로고
    • Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages
    • Chinetti G, Griglio S, Antonucci M, Torra IP, Delerive P, Majd Z, et al. Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. J Biol Chem 1998; 273: 25573-80.
    • (1998) J Biol Chem , vol.273 , pp. 25573-25580
    • Chinetti, G.1    Griglio, S.2    Antonucci, M.3    Torra, I.P.4    Delerive, P.5    Majd, Z.6
  • 35
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391: 79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 36
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391: 82-6.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 37
    • 0032746173 scopus 로고    scopus 로고
    • A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response
    • Su CG, Wen X, Bailey ST, Jiang W, Rangwala SM, Keilbaugh SA, et al. A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response. J Clin Invest 1999; 104: 383-9.
    • (1999) J Clin Invest , vol.104 , pp. 383-389
    • Su, C.G.1    Wen, X.2    Bailey, S.T.3    Jiang, W.4    Rangwala, S.M.5    Keilbaugh, S.A.6
  • 38
    • 0035810980 scopus 로고    scopus 로고
    • Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells
    • Poddar R, Sivasubramanian N, DiBello PM, Robinson K, Jacobsen DW. Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells. Circulation 2001; 103: 2717-30.
    • (2001) Circulation , vol.103 , pp. 2717-2730
    • Poddar, R.1    Sivasubramanian, N.2    DiBello, P.M.3    Robinson, K.4    Jacobsen, D.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.