Vascular reactivity in arterioles from normal and alloxan-diabetic mice: Studies on single perfused islets

Diabetes

Volumn 56, Issue 1, 2007, Pages 107-112

  En, Yin Lai ^a   Jansson, Leif ^a,c   Patzak, Andreas ^a,b   Persson, A Erik G ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ALLOXAN; ANGIOTENSIN II; GLUCOSE; INSULIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BLOOD VESSEL REACTIVITY; CAPILLARY; CONTROLLED STUDY; DIABETES MELLITUS; GLOMERULUS; ISOLATION PROCEDURE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS BLOOD FLOW; PANCREAS ISLET; PATHOGENESIS; PERFUSION; PRIORITY JOURNAL; REGULATORY MECHANISM; VASCULAR SMOOTH MUSCLE; VASCULARIZATION; VASOCONSTRICTION; VASODILATATION;

ANGIOTENSIN II; ANIMALS; ARTERIOLES; DIABETES MELLITUS, EXPERIMENTAL; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; POTASSIUM CHLORIDE; REFERENCE VALUES;

EID: 33847057356     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0623     Document Type: Article

References (42)

1. Bonner-Weir S: The microvasculature of the pancreas, with emphasis on that of the islets of Langerhans: anatomy and functional implications. In The Pancreas. Biology, Pathobiology, and Disease. 2nd ed. Go VLW, DiMagno EP, Gardner JD, Lebenthal E, Reber HA, Scheele GA, Eds. New York, Raven Press, 1993, p. 759-768
2. Brunicardi FC, Stagner J, Bonner-Weir S, Wayland H, Kleinman R, Livingston E, Guth P, Menger M, McCuskey R, Intaglietta M, Charles A, Ashley S, Cheung A, Ipp E, Gilman S, Howard T, Passaro E Jr: Microcirculation of the islets of Langerhans: Long Beach Veterans Administration Regional Medical Education Center Symposium. Diabetes 45:385-392, 1996
3. Lammert E, Cleaver O, Melton D: Induction of pancreatic differentiation by signals from blood vessels. Science 294:564-567, 2001
4. Johansson M, Mattsson G, Andersson A, Jansson L, Carlsson PO: Islet endothelial cells and pancreatic β-cell proliferation: atudeis in vitro and during pregnancy in adult rats. Endocrinology 147:2315-2324, 2006
5. Nikolova G, Jabs N, Konstantinova I, Domogatskaya A, Tryggvason K, Sorokin L, Fassler R, Gu G, Gerber HP, Ferrara N, Melton DA, Lammert E: The vascular basement membrane: a niche for insulin gene expression and beta cell proliferation. Dev Cell 10:397-405, 2006
6. Thiel A: [Studies on vascular system of pancreatic lobule in various mammals with special reference to the capillary glomeruli of Islands of Langerhans]. Z Zellforsch Mikrosk Anat 39:339-372, 1954 (article in German)
7. Samols E, Stagner JI, Ewart RB, Marks V: The order of islet microvascular cellular perfusion is B-A-D in the perfused rat pancreas. J Clin Invest 82:350-353, 1988
8. Henderson JR, Daniel PM, Fraser PA: The pancreas as a single organ: the influence of the endocrine upon the exocrine part of the gland. Gut 22:158-167, 1981
9. Jansson L: The regulation of pancreatic islet blood flow. Diabetes Metab Rev 10:407-416, 1994
10. Jansson L: Dissociation between pancreatic islet blood flow and insulin release in the rat. Acta Physiol Scand 124:223-228, 1985
11. Moldovan S, Livingston E, Zhang RS, Kleinman R, Guth P, Brunicardi FC: Glucose-induced islet hyperemia is mediated by nitric oxide. Am J Surg 171:16-20, 1996
12. G-nitro-L-arginine causes a preferential decrease in pancreatic islet blood flow in normal rats and spontaneously diabetic GK rats. Endocrinology 135:849-853, 1994
13. Carlsson PO, Berne C, Jansson L: Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in rats. Diabetologia 41:127-133, 1998
14. Atef N, Portha B, Penicaud L: Changes in islet blood flow in rats with NIDDM. Diabetologia 37:677-680, 1994
15. Wasserman SM, Topper JN: Adaptation of the endothelium to fluid flow: in vitro analyses of gene expression and in vivo implications. Vasc Med 9:35-45, 2004
16. Brooks AR, Lelkes PI, Rubanyi GM: Gene expression profiling of vascular endothelial cells exposed to fluid mechanical forces: relevance for focal susceptibility to atherosclerosis. Endothelium 11:45-57, 2004
17. Resnick N, Yahav H, Shay-Salit A, Shushy M, Schubert S, Zilberman LC, Wofovitz E: Fluid shear stress and the vascular endothelium: for better and for worse. Prog Biophys Mol Biol 81:177-199, 2003
18. Patzak A, Mrowka R, Storch E, Hocher B, Persson PB: Interaction of angiotensin II and nitric oxide in isolated perfused afferent arterioles of mice. J Am Soc Nephrol 12:1122-1127, 2001
19. Patzak A, Lai EY, Mrowka R, Steege A, Persson PB, Persson AE: AT1 receptors mediate angiotensin II-induced release of nitric oxide in afferent arterioles. Kidney Int 66:1949-1958, 2004
20. Edwards RM: Segmental effects of norepinephrine and angiotensin II on isolated renal microvessels. Am J Physiol 244:F526-F534, 1983
21. Hellerstrom C: Effects of carbohydrates on the oxygen consumption of isolated pancreatic islets of mice. Endocrinology 81:105-112, 1967
22. Mattsson G, Danelsson A, Kriz V, Carlsson P-O, Jansson L: Endothelial cells in endogenous and transplanted islets: differences in the expression of angiogenic peptides and receptors. Pancreatology 6:86-95, 2006
23. Carlsson PO, Jansson L, Östenson CG, Källskog Ö: Islet capillary blood pressure increase mediated by hyperglycemia in NIDDM GK rats. Diabetes 46:947-952, 1997
24. Pipeleers D, Kiekens R, Ling Z, Wilikens A, Schuit F: Physiologic relevance of heterogeneity in the pancreatic beta-cell population. Diabetologia 37 (Suppl. 2):S57-S64, 1994
25. Hellman B: The volumetric distribution of the pancreatic islet tissue in young and old rats. Acta Endocrinol (Copenh) 31:91-106, 1959
26. Lifson N, Lassa CV, Dixit PK: Relation between blood flow and morphology in islet organ of rat pancreas. Am J Physiol 249:E43-E48, 1985
27. Jansson L: Microsphere distribution in the pancreas of anesthetized rats. Alloxan stimulates the blood flow to all islets whereas glucose only affects the blood perfusion of a subgroup of islets. Int J Pancreatol 20:69-74, 1996
28. MacGregor RR, Williams SJ, Tong PY, Kover K, Moore WV, Stehno-Bittel L: Small rat islets are superior to large islets in in vitro function and in transplantation outcomes. Am J Physiol Endocrinol Metab 290:E771-E779, 2006
29. Jansson L, Hellerström C: Glucose-induced changes in pancreatic islet blood flow mediated by central nervous system. Am J Physiol 251:E644-E647, 1986
30. Welsh M, Andersson A: Adenosine uptake by isolated mouse pancreatic islets. Biochem Pharmacol 30:2075-2080, 1981
31. Carlsson PO, Olsson R, Källskog Ö, Bodin B, Andersson A, Jansson L: Glucose-induced islet blood flow increase in rats: interaction between nervous and metabolic mediators. Am J Physiol Endocrinol Metab 283:E457-E464, 2002
32. Atef N, Ktorza A, Picon L, Penicaud L: Increased islet blood flow in obese rats: role of the autonomic nervous system. Am J Physiol 262:E736-E740, 1992
33. Farah AE: Glucagon and the circulation. Pharmacol Rev 35:181-217, 1983
34. Kolb H: Benign versus destructive insulitis. Diabetes Metab Rev 13:139-146, 1997
35. Donath MY, Ehses JA, Maedler K, Schumann DM, Ellingsgaard H, Eppler E, Reinecke M: Mechanisms of β-cell death in type 2 diabetes. Diabetes 54 (Suppl. 2):S108-S113, 2005
36. Kolb H, Mandrup-Poulsen T: An immune origin of type 2 diabetes? Diabetologia 48:1038-1050, 2005
37. Jansson L, Andersson A: Nitric oxide and pancreatic islet blood flow after induced portal hypertension in rats. Pancreas 14:280-284, 1997
38. Svensson AM, Sandler S, Jansson L: The blood flow in pancreaticoduodenal grafts in rats: inhibition of nitric oxide synthase preferentially decreases islet blood flow. Eur J Pharmacol 275:99-103, 1995
39. Pallone TL, Silldorff EP: Pericyte regulation of renal medullary blood flow. Exp Nephrol 9:165-170, 2001
40. Lukinius A, Jansson L, Korsgren O: Ultrastructural evidence for blood microvessels devoid of an endothelial cell lining in transplanted pancreatic islets. Am J Pathol 146:429-435, 1995
41. Joyce JA, Laakkonen P, Bernasconi M, Bergers G, Ruoslahti E, Hanahan D: Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 4:393-403, 2003
42. Stagner JI, Samols E: The vascular order of islet cellular perfusion in the human pancreas. Diabetes 41:93-97, 1992