Molecular genetic alterations in pleomorphic xanthoastrocytoma

Acta Neuropathologica

Volumn 91, Issue 3, 1996, Pages 293-297

  Paulus, Werner ^a,b   Lisle, David K ^a   Tonn, Jörg C ^c   Wolf, Helmut K ^d   Roggendorf, Wolfgang ^c   Reeves, Steven A ^a   Louis, David N ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF BONN   (Germany)

Author keywords

Astrocytoma; Epidermal growth factor receptor; Glioma; Loss of heterozygosity; p53

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR;

ADOLESCENT; ADULT; ARTICLE; ASTROCYTOMA; CANCER GENETICS; CHILD; CLINICAL ARTICLE; DNA DETERMINATION; DNA SEQUENCE; ELECTROPHORETIC MOBILITY; EXON; FEMALE; GENE AMPLIFICATION; GLIOBLASTOMA; GLIOMA; HUMAN; HUMAN TISSUE; MALE; MISSENSE MUTATION; NEUROPATHOLOGY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; RECEPTOR GENE; RECURRENT CANCER; SCHOOL CHILD; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0030031291     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050428     Document Type: Article

References (29)

1. Allegranza A, Ferraresi S, Bruzzone M, Giombini S (1991) Cerebromeningeal pleomorphic xanthoastrocytoma, Report on four cases: clinical, radiologic and pathologic features (including a case with malignant evolution). Neurosurg Rev 14:43-49
2. Deimling A von, Eibl RH, Ohgaki H, Louis DN, Ammon K von, Petersen I, Kleihues P, Chung RY, Wiestler OD, Seizinger BR (1992) p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. Cancer Res 52:2987-2990
3. Deimling A von, Louis DN, Ammon K von, Petersen I, Hoell T, Chung RY, Martuza RL, Schoenfeld DA, Yasargil G, Wiestler OD, Seizinger BR (1992) Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. J Neurosurg 77:295-301
4. Ekstrand AJ, James CD, Cavenee WK, Seliger B, Pettersson RF, Collins VP (1991) Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res 51:2164-2172
5. Hollstein M, Rice K, Greenblatt MS, Soussi T, Fuchs R, Sorlie T, Hovig E, Smith-Sorensen B, Montesano R, Harris CC (1994) Database of the p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res 22:3551-3555
6. Hunter SB, Abbott K, Varma VA, Olson JJ, Barnett DW, James CD (1995) Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue. J Neuropathol Exp Neurol 54:57-64
7. Kepes JJ (1993) Pleomorphic xanthoastrocytoma: the birth of a diagnosis and a concept. Brain Pathol 3:269-274
8. Kepes JJ, Rubinstein LJ, Eng LF (1979) Pleomorphic xanthoastrocytoma: a distinctive meningocerebral glioma of young subjects with relatively favorable prognosis. A study of 12 cases. Cancer 44:1839-1852
9. Kepes JJ, Rubinstein LJ, Ansbacher L, Schreiber DJ (1989) Histopathological features of recurrent pleomorphic xanthoastrocytomas: further corroboration of the glial nature of this neoplasm. A study of 3 cases. Acta Neuropathol 78:585-593
10. Kleihues P, Burger PC, Scheithauer BW (1993) Histological typing of tumours of the central nervous system, 2nd edn. Springer, Berlin
11. Kleihues P, Burger PC, Scheithauer BW (1993) The new WHO classification of brain tumours. Brain Pathol 3:255-268
12. Kraus JA, Bolln C, Wolf HK, Neumann J, Kindermann D, Fimmers R, Forster F, Baumann A, Schlegel U (1994) TP53 alterations and clinical outcome in low-grade astrocytomas. Genes Chromosome Cancer 10:143-149
13. Leenstra S, Bijlsma EK, Troost D, Oosting J, Westerveld A, Bosch DA, Hulsebos TJM (1994) Allele loss on chromosomes 10 and 17p and epidermal growth factor receptor gene amplification in human malignant astrocytoma related to prognosis. Br J Cancer 70:684-689
14. Litofsky NS, Hinton D, Raffel C (1994) The lack of a role for p53 in astrocytomas in pediatric patients. Neurosurgery 34:967-972
15. Louis DN (1994) The p53 gene and protein in human brain tumors. J Neuropathol Exp Neurol 53:11-21
16. Louis DN, Gusella JF (1995) A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet 11:412-415
17. Louis DN, Rubio MP, Correa KM, Gusella JF, Deimling A von (1993) Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens. J Neuropathol Exp Neurol 52:507-515
18. n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens. Am J Pathol 141:777-782
19. Macaulay RJ, Jay V, Hoffman HJ, Becker LE (1993) Increased mitotic activity as a negative prognostic indicator in pleomorphic xanthoastrocytoma. Case report. J Neurosurg 79:761-768
20. Neubauer A, Neubauer B, He M, Effert P, Iglehart D, Frye RA, Liu E (1992) Analysis of gene amplification in archival tissue by differential polymerase chain reaction. Oncogene 7:1019-1025
21. Ohgaki H, Eibl RH, Schwab M, Reichel MB, Mariani L, Gehring M, Petersen I, Höll T, Wiestler OD, Kleihues P (1993) Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system. Mol Carcinog 8:74-80
22. Palma L, Maleci A, Di Lorenzo N, Lauro GM (1985) Pleomorphic xanthoastrocytoma with 18-year survival. Case report. J Neurosurg 63:808-810
23. Paulus W, Peiffer J (1988) Does the pleomorphic xanthoastrocytoma exist? Problems in the application of immunological techniques to the classification of brain tumors. Acta Neuropathol 76:245-252
24. Rubio MP, Correa KM, Ueki K, Mohrenweiser HW, Gusella JF, Deimling A von, Louis DN (1994) The putative glioma tumor suppressor gene on chromosome 19q maps between APOC2 and HRC. Cancer Res 54:4760-4763
25. Toguchida J, Yamaguchi T, Ritchie B (1992) Mutation spectrum of the p53 gene in bone and soft tissue sarcomas. Cancer Res 52:6194-6199
26. Tonn JC, Paulus W, Warmuth-Metz M, Schachenmayr W, Sörensen N, Roosen K (1995) Pleomorphic xanthoastrocytoma: report of six cases with special consideration of diagnostical and therapeutical pitfalls. Surg Neurol (in press)
27. Wasdahl DA, Scheithauer BW, Andrews BT, Jeffrey RA Jr (1994) Cerebellar pleomorphic xanthoastrocytoma: case report. Neurosurgery 35:947-950
28. Weldon-Linne CM, Victor TA, Groothuis DR, Vick NA (1983) Pleomorphic xanthoastrocytoma. Ultrastructural and immunohistochemical study of a case with a rapidly fatal outcome following surgery. Cancer 52:2055-2063
29. Whittle IR, Gordon A, Misra BK, Shaw JF, Steers AJ (1989) Pleomorphic xanthoastrocytoma. Report of four cases. J Neurosurg 70:463-468