Dominant-negative α-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells

Diabetes

Volumn 56, Issue 1, 2007, Pages 204-210

  Veluthakal, Rajakrishnan ^a,b   Kaur, Hitchintan ^a,b   Goalstone, Marc ^b,c   Kowluru, Anjaneyulu ^a,b  

^a WAYNE STATE UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLALLYLTRANSFERASE; ENZYME INHIBITOR; FARNESYL TRANS TRANSFERASE; GERANYLTRANSFERASE; GLUCOSE; HOLOENZYME; INSULIN; POTASSIUM CHLORIDE; PROTEIN INHIBITOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME REGULATION; GENE OVEREXPRESSION; INSULIN RELEASE; MUTANT; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; STIMULATION; WESTERN BLOTTING;

ANIMALS; CELL LINE; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; GERANYLTRANSTRANSFERASE; GLUCOSE; IMIDAZOLES; ISLETS OF LANGERHANS; LEUCINE; POTASSIUM CHLORIDE; PROTEIN SUBUNITS; RATS;

EID: 33847042302     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0668     Document Type: Article

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