Glucose augmentation of mastoparan-stimulated insulin secretion in rat and human pancreatic islets

Diabetes

Volumn 47, Issue 7, 1998, Pages 1053-1057

  Straub, Susanne G ^a,c   James, Roger F L ^b   Dunne, Mark J ^c   Sharp, Geoffrey W G ^a,c  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOISOCAPROIC ACID; MANNOHEPTULOSE; MASTOPARAN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL TYPE; DRUG RECEPTOR BINDING; EXOCYTOSIS; EXTRACELLULAR CALCIUM; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STIMULUS RESPONSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; FORSKOLIN; GLUCOSE; GUANOSINE TRIPHOSPHATE; HUMANS; INSULIN; ISLETS OF LANGERHANS; KETO ACIDS; MALE; MANNOHEPTULOSE; ORGAN CULTURE TECHNIQUES; PEPTIDES; PERTUSSIS TOXIN; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; VIRULENCE FACTORS, BORDETELLA; WASP VENOMS;

EID: 0031780223     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.47.7.1053     Document Type: Article

References (32)

1. Hirai Y, Yasuhara T, Yoshida H, Nakajima T, Fujino M, Kitada C: A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii. Chem Pharm Bull (Tokyo) 27:1942-1944, 1979
2. Yokokawa N, Komatsu M, Takeda T, Aizawa T, Yamada T: Mastoparan, a wasp venom, stimulates insulin release by pancreatic islets through pertussis toxin sensitive GTP-binding protein. Biochem Biophys Res Commun 158:712-716, 1989
3. Komatsu M, Aizawa T, Yokokawa N, Sato Y, Okada N, Takasu N, Yamada T: Mastoparan-induced insulin release from rat pancreatic islets. Endocrinology 130:221-228, 1992
4. Hillaire-Buys D, Mousli M, Landry Y, Bockaert J, Fehrentsz JA, Rouot B: Insulin releasing effects of mastoparan and amphiphilic substance P receptor antagonists on RINm5F insulinoma cells. Mol Cell Biochem 109:133-138, 1992
5. Jones PM, Mann FM, Persaud SJ, Wheeler-Jones CPD: Mastoparan stimulates insulin secretion from pancreatic β-cells by effects at a late stage in the secretory pathway. Mol Cell Endocrinol 94:97-103, 1993
6. Konrad RJ, Young RA, Record RD, Smith RM, Butkerait P, Manning D, Jarett L, Wolf BA: The heterotrimeric G-protein Gi is localized to the insulin secretory granules of beta-cells and is involved in insulin exocytosis. J Biol Chem 270:12869-12876, 1995
7. Kowluru A, Seavey SE, Rabaglia ME, Metz SA: Non-specific stimulatory effects of mastoparan on pancreatic islet nucleoside diphosphokinase activity: dissociation from insulin secretion. Biochem Pharmacol 49:263-266, 1995
8. 2+-independent late site in stimulus-secretion coupling: studies with the RINm5F β-cell line. J Biol Chem 268:23297-23306, 1993
9. Eddlestone GT, Komatsu M, Shen L, Sharp GWG: Mastoparan increases the intracellular free calcium concentration in two insulin-secreting cell lines by inhibition of ATP-sensitive potassium channels. Mol Pharmacol 47:787-797, 1995
10. Higashyima T, Uzu S, Nakajima T, Ross EM: Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). J Biol Chem 263:6491-6494, 1988
11. Higashijima T, Burnier J, Ross EM: Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines: mechanism and structural determinants of activity. J Biol Chem 265:14176-14186, 1990
12. 125I-Tyr3,Cys11]mastoparan to Go. J Biol Chem 266:12655-12661, 1991
13. Ross EM, Higashijima T: Regulation of G-protein activation by mastoparans and other cationic peptides. Methods Enzymol 237:26-37, 1994
14. Sukumar M, Ross EM, Higashijima T: A Gs-selective analog of the receptor-mimetic peptide mastoparan binds to Gs alpha in a kinked helical conformation. Biochemistry 36:3632-3639, 1997
15. Gomperts BD: Ge: a GTP-binding protein mediating exocytosis. Annu Rev Physiol 52:591-606, 1990
16. 2+ influx in rat pancreatic B-cell. Diabetes 41:438-443, 1992
17. + channels in mouse B cells. J Clin Invest 89:1288-1295, 1992
18. +) permeability. Biochem Pharmacol 43:2483-2485, 1992
19. 2+-independent pathways in stimulus-coupling to insulin secretion can be distinguished by their GTP requirements: studies on rat pancreatic islets. Endocrinology 139:1172-1183, 1998
20. 2+: new insights into stimulus-secretion coupling. Diabetes 46:1928-1938, 1997
21. 2+ in rat pancreatic islets. Proc Natl Acad Sci U S A 92:10728-10732, 1995
22. Metz SA, Rabaglia ME, Pintar TJ: Selective inhibitors of GTP synthesis impede exocytotic insulin release from intact rat islets. J Biol Chem 167:12517-12527, 1992
23. Metz SA, Meredith M, Rabaglia ME, Kowluru A: Small elevations of glucose concentration redirect and amplify the synthesis of guanosine 5′-triphosphate in rat islets. J Clin Invest 92:872-882, 1993
24. 2+-induced insulin secretion by glucose in intact rat islets. J Clin Invest 96:811-821, 1995
25. Lacey PE, Kostianovsky M: Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16:35-39, 1967
26. London NJM, James RFL, Bell PRF: Islet purification. In Pancreatic Islet Transplantation. Ricordi C, Ed. Austin, TX, Landes, 1992, p. 113-123
27. ATP channels in pancreatic β-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nat Med 2:1344-1347, 1996
28. Herbert V, Lau K-S, Gottlieb CW, Bleicher SJ: Coated charcoal immunoassay of insulin. J Clin Endocrinol 25:1375-1384, 1965
29. Metz S, Rabaglia ME, Stock JB, Kowluru A: Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins. Biochem J 295:31-40, 1993
30. Skoglund G, Bliss CR, Sharp GW: Galanin-stimulated high-affinity GTPase activity in plasma membranes from RINm5F cells. Diabetes 42:74-79, 1993
31. Sharp GWG: Mechanisms of inhibition of insulin release. Am J Physiol 271:C1781-C1799, 1996
32. 2+. Mol Pharmacol 50:1047-1054, 1996