Tachykinin-1 receptor stimulates proinflammatory gene expression in lung epithelial cells through activation of NF-κB via a Gq-dependent pathway

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 2, 2007, Pages

  Williams, Ronald ^a   Zou, Xiaoyan ^a   Hoyle, Gary W ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

A549; Erk; G protein coupled receptor; Substance P

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; CALCIUM; CHEMOKINE; G PROTEIN COUPLED RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PROTEASOME; RAF PROTEIN; RAS PROTEIN; RECEPTOR BLOCKING AGENT; SUBSTANCE P; TACHYKININ RECEPTOR;

ARTICLE; CYTOKINE RELEASE; DNA FLANKING REGION; DOSE RESPONSE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFLAMMATION; LUNG DISEASE; LUNG INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; REPORTER GENE; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ENZYME ACTIVATION; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; INFLAMMATION MEDIATORS; LEUPEPTINS; LUCIFERASES; LUNG; MICE; NF-KAPPA B; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, NEUROKININ-1; SIGNAL TRANSDUCTION; SUBSTANCE P; TRANSFECTION;

EID: 33847039610     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00475.2005     Document Type: Article

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