Rapid Activation of PDGF-A and -B Expression at Sites of Lung Injury in Asbestos-exposed Rats

American Journal of Respiratory Cell and Molecular Biology

Volumn 17, Issue 2, 1997, Pages 129-140

  Liu, Jing Yao ^a   Morris, Gilbert F ^a   Lei, Wei Hong ^a   Hart, Charles E ^a   Lasky, Joseph A ^a   Brody, Arnold R ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHRYSOTILE; MESSENGER RNA; ONCOPROTEIN; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; PLATELET-DERIVED GROWTH FACTOR A; VIMENTIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; GENETICS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG; LUNG FIBROSIS; METABOLISM; PATHOLOGY; RAT;

ANIMALS; ASBESTOS, SERPENTINE; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-SIS; PULMONARY FIBROSIS; RATS; RNA, MESSENGER; VIMENTIN;

EID: 0031203480     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.17.2.2956     Document Type: Article

References (51)

1. Ross, R., E. W. Raines, and D. F. Bowen-Pope. 1986. The biology of platelet-derived growth factor. Cell 46:155-169.
2. Bonner, J. C., A. L. Goodell, P. G. Coin, and A. R. Brody. 1993. Chrysotile asbestos upregulates gene expression and production of alpha-receptors for platelet-derived growth factor (PDGF-AA) on rat lung fibroblasts. J. Clin. Invest. 92:425-430
3. Boström, H., K. Willetts, M. Pekny, P. Levéen, P. Lindahl, H. Hedstrand, M. Pekna, M. Hellström, S. Gebre-Medhin, M. Schalling, M. Nilsson, S. Kurland, J. Törnell, J. K. Heath, and C. Betsholtz. 1996. PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell 85:863-873.
4. Ferns, G. A. A., E. W. Raines, K. H. Sprugel, A. S. Motani, M. A. Reidy, and R. Ross. 1991. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science 253:1129-1132.
5. Levéen, P., M. Pekny, S. Gebre-Medhin, B. Swolin, E. Larsson, and C. Betsholtz. 1994. Mice deficient for PDGF-B show renal, cardiovascular, and hematological abnormalities. Genes Dev. 8:1875-1887.
6. Pierce, G. F., J. E. Tarpley, R. M. Allman, P. S. Goode, C. M. Serdar, B. Morris, T. A. Mustoe, and J. Vande Berg. 1994. Tissue repair processes in healing chronic pressure ulcers treated with recombinant platelet-derived growth factor BB . Am. J. Pathol. 145:1399-1410.
7. Ross, R., J. A. Glomset, B. Kariya, and L. Harker. 1974. A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc. Natl. Acad. Sci. USA 71:1207-1210.
8. Heldin, C. H., A. Östman, and B. Westermark. 1993. Structure of platelet-derived growth factor: implications for functional properties. Growth Factors 8:245-252.
9. Seifert, R. A., C. E. Hart, P. E. Philips, J. W. Forstrom, R. Ross, M. Murray, and D. F. Bowen-Pope. 1989. Two different subunits associate to create isoform-specific platelet-derived growth factor receptors. J. Biol. Chem. 264:8771-8778.
10. Heldin, C.-H., A. Ernlund, C. Rorsman, and L. Rönnstrand. 1989. Dimerization of B-type platelet-derived growth factor receptors occurs after ligand binding and is closely associated with receptor kinase activation. J. Biol. Chem. 264:8905-8912.
11. Brody, A. R. 1992. Asbestos exposure as a model of inflammation inducing interstitial pulmonary fibrosis. In Inflammation: Basic Principles and Clinical Correlates. J. Gallin, A. Goldstein, and R. Snyderman, editors. Raven Press, Ltd., New York. 1033-1049.
12. Brody, A. R., and L. H. Overby. 1989. Incorporation of tritiated thymidine by epithelial and interstitial cells in bronchiolar-alveolar regions of asbestos-exposed rats. Am. J. Pathol. 134:133-144.
13. Chang, L. Y., L. H. Overby, A. R. Brody, and J. D. Crapo. 1988. Progressive lung cell reactions and extracellular matrix production after a brief exposure to asbestos. Am. J. Pathol. 131:156-170.
14. Liu, J.-Y., G. F. Morris, W.-H. Lei, M. Corti, and A. R. Brody. 1996. Up-regulated expression of transforming growth factor-α in the bronchiolar-alveolar duct regions of asbestos-exposed rats. Am. J. Pathol 149:205-217.
15. Morris, G. F., and M. B. Mathews. 1991. The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site. J. Virol. 65:6397-6406.
16. Hammacher, A., U. Hellman, A. Johnsson, A. Ostman, K. Gunnarson, B. Westermark, A. Wasteson, and C.-H. Heldin. 1988. A major part of PDGF purified from human platelets is a heterodimer of one A chain and one B chain. J. Biol. Chem. 263:16493-16498.
17. Ansel, J. C., J. P. Tiesman, J. E. Olerud, J. G. Krueger, J. F. Krane, D. C. Tara, G. D. Shipley, D. Gilbertson, M. L. Usui, and C. E. Hart. 1993. Human keratinoytes are a major source of cutaneous platelet-derived growth factor. J. Clin. Invest. 92:671-678.
18. Qu, Z., M. Picou, T. T. Dang, E. Angell, S. R. Planck, C. E. Hart, and J. T. Rosenbaum. 1994. Immunolocalization of basic fibroblast growth factor and platelet-derived growth factor-A during adjuvant arthritis in the Lewis rat. Am. J. Pathol. 145:1127-1139.
19. Ross, R., J. Masuda, E. W. Raines, A. M. Gown, S. Katsuda, M. Sasahara, L. T. Malden, H. Masuko, and H. Sato. 1990. Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science 248:1009-1012.
20. Iida, H., R. Seifert, C. E. Alpers, R. G. K. Gronwald, P. E. Phillips, P. Pritzl, K. Gordon, A. M. Gown, R. Ross, D. E. Bowen Pope, and R. J. Johnson. 1991. Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat. Proc. Natl. Acad. Sci. USA 88:6560-6564.
21. Shiraishi, T., S. Morimoto, K. Itoh, H. Sato, K. Sugihara, T. Onishi, and T. Ogihara. 1989. Radioimmunoassay of human platelet-derived growth factor using monoclonal antibody toward a synthetic 73-97 fragment of its B-chain. Clin. Chim. Acta 184:65-74.
22. Warheit, D. B., G. George, L. H. Hill, R. Snyderman, and A. R. Brody. 1985. Inhaled asbestos activates a complement-dependent chemotactic factor for macrophages. Lab. Invest. 52:505-514.
23. McGavran, P. D., L. M. Moore, and A. R. Brody. 1990. Inhalation of chrysotile asbestos induces rapid cellular proliferation in small pulmonary vessels of mice and rats. Am. J. Pathol. 136:695-705.
24. McGavran, P. D., C. J. Butterick, and A. R. Brody. 1990. Tritiated thymidine incorporation and the development of an interstitial lesion in the bronchiolar-alveolar regions of the lungs of normal and complement-deficient mice after inhalation of chrysotile asbestos. J. Env. Pathol. Toxicol. Oncol. 6:377-392.
25. Coin, P. G., A. Osornio-Vargas, V. L. Roggli, and A. R. Brody. 1996. Pulmonary fibrogenesis after three consecutive inhalation exposures to chrysotile asbestos. Am. J. Respir. Crit. Care Med. 154:1511-1519.
26. Yi, E. S., H. Lee, S. Yin, P. Piguet, I. Sarosi, S. Kaufmann, J. Tarpley, N.-S. Wang, and T. R. Ulich. 1996. Plalelet-derived growth factor causes pulmonary cell proliferation and collagen deposition in vivo. Am. J. Pathol. 149:539-548.
27. Sporn, M. B., and A. B. Roberts, editors. 1991. Peptide Growth Factors and Their Receptors. Vol. I-II. Springer-Verlag. Newr York.
28. Zhang, K., K. C. Flanders, and S. H. Phan. 1995. Cellular localization of transforming growth factor-β expression in bleomycin-induced pulmonary fibrosis. Am. J. Pathol 147:352-361.
29. Korfhagen, T. R., R. J . Swantz, S. E. Wert, J. M. McCarty, C. B. Kerlakian, S. W. Glasser, and J. A. Whitsett. 1994. Respiratory epithelial cell expression of human transforming growth factor-α induces lung fibrosis in transgenic mice. J. Clin. Invest. 93:1691-1699.
30. Piguet, P. F., M. A. Collart, G. E. Grau, A. P. Sappino, and P. Vassalli. 1990. Requirement of tumor necrosis factor for development of silica-induced pulmonary fibrosis. Nature 344:245-247.
31. Broekelmann, T. J., A. H. Liuper, T. V. Colby, and J. A. McDonald. 1991. Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibosis. Proc. Natl. Acad. Sci. USA 88:6642-6646.
32. Yasui, W., J. Zhong-Qiang, H. Kuniyasu, A. Ayhan, H. Yokozaki, H. Ito, and E. Tahara. 1992. Expression of transforming growth factor-α in human tissues: immunohistochemical study and Northern blot analysis. Virchows Arch. 421:513-519.
33. Piguet, P. F., C. Ribaux, V. Karpuz, G. E. Grau, and Y. Kapanci. 1993. Expression and localization of tumor necrosis factor α and its mRNA in idiopathic pulmonary fibrosis. Am. J. Pathol. 143:651-655.
34. Antoniades, H. N., M. A. Bravo, R. E. Avila, T. Galanopoulos, J. Neville-Golden, M. Maxwell, and M. Selman. 1990. Platelet-derived growth factor in idiopathic pulmonary fibrosis. J. Clin. Invest. 86:1055.
35. Quinlan, T. R., K. A. BéruBé, J. P. Marsh, Y. M. W. Janssen, P. Taisi, K. O. Leslie, D. Hemenway, P. T. O'Shaughnessy, P. Vacek, and B. T. Mossman, 1995. Patterns of inflammation, cell proliferation, and related gene expression in lung after inhalation of chrysotile asbestos. Am. J. Pathol. 147:729-739.
36. Mossman, B. T., J. P. Marsh, A. Sesko, S. Hill, A. Shatos, J. Doherty, K. Petruska, B. Adler, D. Hemenway, R. Mickey, P. Vacek, and E. Kagan. 1990. Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethyleneglycol conjugated catalase in a rapid inhalation model of asbestosis. Am. Rev. Respir. Dis. 141:1266-1271.
37. Lindner, V., and M. A. Reidy. 1995. Platelet-derived growth factor ligand and receptor expression by large vessel endothelium in vivo. Am. J. Pathol. 146:1488-1497.
38. Badgett, A., J. C. Bonner, and A. R. Brody. 1996. Interferon-γ modulates lung macrophage production of PDGF-BB and fibroblast growth. J. Lipid Mediat. Cell Signal. 13:89-47.
39. Moore, K. W., A. O'Garra, R. deWaal Malfut, P. Viera, and R. Mossman. 1993. Interleukin 10. Annu. Rev. Immunol. 11:165-190.
40. Roberts, A. B., M. A. Anzano, L. M. Wakefield, N. S. Roche, D. F. Stern, and M. B. Sporn. 1985. Type β transforming growth factor: a bifunctional regulator of cellular growth. Proc. Natl. Acad. Sci. USA 82:119-123.
41. Perdue, T. D., and A. R. Brody. 1994. Distribution of transforming growth factor-β1, fibronectin, and smooth muscle actin in asbestos-induced pulmonary fibrosis in rats. J. Histochem. Cytochem. 42:1-10.
42. Brody, A. R., L. H. Hill, B. Adkins, Jr., and R. W. O'Connor. 1981. Chrysotile asbestos inhalation in rats: deposition pattern and reaction of alveolar epithelium and pulmonary macrophages. Am. Rev. Respir. Dis. 123:670-679.
43. Rom, W. N., W. D. Travis, and A. R. Brody. 1991. Cellular and molecular bases of the asbestos-related diseases. Am. Rev. Respir. Dis. 143:408-422.
44. Mishra, A., J.-Y. Liu, A. R. Brody, and G. F. Morris. 1996. Inhaled asbestos fibers induce p53 expression in the rat lung. Am. J. Respir. Cell Mol. Biol. 15:479-485.
45. Antoniades, H. N., T. Galanopoulos, J. Neville-Golden, C. P. Kiritsy, and S. E. Lynch. 1994. p53 expression during normal tissue regeneration in response to acute cutaneous injury in swine. J. Clin. Invest. 93:2206-2214.
46. Shin, T. H., A. J. Paterson, and J. E. Kudlow. 1995. p53 stimulates transcription from the transforming growth factor alpha promoter: a potential growth-stimulatory role for p53. Mol. Cell. Biol. 15:4694-4701.
47. Heintz, N. H., Y. M. Janssen, and B. T. Mossman. 1993. Persistent induction of c-fos and c-jun expression by asbestos. Proc. Natl. Acad. Sci. USA 90:3299-3303.
48. Janssen, Y. M., A. Barchowsky, M. Treadwell, K. E. Driscoll, and B. T. Mossman. 1995. Asbestos induces nuclear factor kappa B (NF-kappa B) DNA-binding activity and NF-kappa B-dependent gene expression in tracheal epithelial cells. Proc. Natl. Acad. Sci. USA 92:8458-8462.
49. Olashaw, N. D., T. F. Kowalik, E. S. Huang, and W. J. Pledger. 1992. Induction of NF-kappa B-like activity by platelet-derived growth factor in mouse fibroblasts. Mol. Biol. Cell. 3:1131-1139.
50. Freter, R. R., J. A. Alberta, G. Y. Hwang, A. L. Wrentmore, and C. D. Stiles. 1996. Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-kappa B and a 90-kDa phosphoprotein coactivator. J. Biol. Chem. 271:17417-17424.
51. Lasky, J. A., P. G. Coin, P. M. Lindroos, L. L. Ostrowski, A. R. Brody, and J. C. Bonner. 1995. Chrysotile asbestos stimulates gene expression and secretion of PDGF-AA by rat fibroblasts in vitro: evidence for an autocrine loop. Am. J. Respir. Cell Mol. Biol. 12:162-170.