Impact of type 2 diabetes on nitric oxide and adrenergic modulation of myocardial perfusion

Diabetes

Volumn 56, Issue 2, 2007, Pages 468-475

  Madsen, Mette Marie ^a   Søndergaard, Hanne M ^a   Bøttcher, Morten ^a   Buus, Niels H ^a   Schmitz, Ole ^a   Bøtker, Hans E ^a   Nielsen, Torsten T ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENTOLAMINE;

ADRENERGIC ACTIVITY; ADULT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIABETIC PATIENT; FEMALE; HEART MUSCLE PERFUSION; HUMAN; HYPEREMIA; ISCHEMIC HEART DISEASE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; VASCULAR RESISTANCE;

ADENOSINE; ADRENERGIC ALPHA-ANTAGONISTS; BLOOD PRESSURE; CORONARY CIRCULATION; DIABETES MELLITUS, TYPE 2; ENZYME INHIBITORS; FEMALE; HEART RATE; HUMANS; HYPEREMIA; MALE; MIDDLE AGED; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENTOLAMINE; SYMPATHETIC NERVOUS SYSTEM; VASCULAR RESISTANCE; VASODILATOR AGENTS;

EID: 33847032878     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0635     Document Type: Article

References (38)

1. Clarkson P, Celermajer DS, Donald AE, Sampson M, Sorensen KE, Adams M, Yue DK, Betteridge DJ, Deanfield JE: Impaired vascular reactivity in insulin-dependent diabetes mellitus is related to disease duration and low density lipoprotein cholesterol levels. J Am Coll Cardiol 28:573-579, 1996
2. McVeigh GE, Brennan GM, Johnston GD, McDermott BJ, McGrath LT, Henry WR, Andrews JW, Hayes JR: Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 35:771-776, 1992
3. Williams SB, Cusco JA, Roddy MA, Johnstone MT, Creager MA: Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 27:567-574, 1996
4. Bottcher M, Madsen MM, Refsgaard J, Buus NH, Dorup I, Nielsen TT, Sorensen K: Peripheral flow response to transient arterial forearm occlusion does not reflect myocardial perfusion reserve. Circulation 103:1109-1114, 2001
5. Nahser PJ Jr, Brown RE, Oskarsson H, Winniford MD, Rossen JD: Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus. Circulation 91:635-640, 1995
6. Nitenberg A, Valensi P, Sachs R, Dali M, Aptecar E, Attali JR: Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function. Diabetes 42:1017-1025, 1993
7. Nitenberg A, Ledoux S, Valensi P, Sachs R, Attali JR, Antony I: Impairment of coronary microvascular dilation in response to cold pressor-induced sympathetic stimulation in type 2 diabetic patients with abnormal stress thallium imaging. Diabetes 50:1180-1185, 2001
8. Johansson BL, Sundell J, Ekberg K, Jonsson C, Seppanen M, Raitakari O, Luotolahti M, Nuutila P, Wahren J, Knuuti J: C-peptide improves adenosine-induced myocardial vasodilation in type 1 diabetes patients. Am J Physiol Endocrinol Metab 286:E14-E19, 2004
9. Yokoyama I, Momomura S, Ohtake T, Yonekura K, Nishikawa J, Sasaki Y, Omata M: Reduced myocardial flow reserve in non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 30:1472-1477, 1997
10. Kjaer A, Meyer C, Nielsen FS, Parving HH, Hesse B: Dipyridamole, cold pressor test, and demonstration of endothelial dysfunction: a PET study of myocardial perfusion in diabetes. J Nucl Med 44:19-23, 2003
11. Di Carli MF, Janisse J, Grunberger G, Ager J: Role of chronic hyperglycemia in the pathogenesis of coronary microvascular dysfunction in diabetes. J Am Coll Cardiol 41:1387-1393, 2003
12. Prior JO, Quinones MJ, Hernandez-Pampaloni M, Facta AD, Schindler TH, Sayre JW, Hsueh WA, Schelbert HR: Coronary circulatory dysfunction in insulin resistance, impaired glucose tolerance, and type 2 diabetes mellitus. Circulation 111:2291-2298, 2005
13. Pitkanen OP, Nuutila P, Raitakari OT, Ronnemaa T, Koskinen PJ, Iida H, Lehtimaki TJ, Laine HK, Takala T, Viikari JS, Knuuti J: Coronary flow reserve is reduced in young men with IDDM. Diabetes 47:248-254, 1998
14. Sundell J, Laine H, Nuutila P, Ronnemaa T, Luotolahti M, Raitakari O, Knuuti J: The effects of insulin and short-term hyperglycaemia on myocardial blood flow in young men with uncomplicated type I diabetes. Diabetologia 45:775-782, 2002
15. Hesse B, Meyer C, Nielsen FS, Sato A, Hove JD, Holm S, Bang LE, Kofoed KF, Svendsen TL, Parving HH, Opie LH: Myocardial perfusion in type 2 diabetes with left ventricular hypertrophy: normalisation by acute angiotensin-converting enzyme inhibition. Eur J Nucl Med Mol Imaging 31:362-368, 2004
16. Buus NH, Bottcher M, Hermansen F, Sander M, Nielsen TT, Mulvany MJ: Influence of nitric oxide synthase and adrenergic inhibition on adenosine-induced myocardial hyperemia. Circulation 104:2305-2310, 2001
17. Hattori N, Rihl J, Bengel FM, Nekolla SG, Standl E, Schwaiger M, Schnell O: Cardiac autonomic dysinnervation and myocardial blood flow in long-term type 1 diabetic patients. Diabet Med 20:375-381, 2003
18. Di Carli MF, Bianco-Batlles D, Landa ME, Kazmers A, Groehn H, Muzik O, Grunberger G: Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus. Circulation 100:813-819, 1999
19. Pop-Busui R, Kirkwood I, Schmid H, Marinescu V, Schroeder J, Larkin D, Yamada E, Raffel DM, Stevens MJ: Sympathetic dysfunction in type 1 diabetes: association with impaired myocardial blood flow reserve and diastolic dysfunction. J Am Coll Cardiol 44:2368-2374, 2004
20. Madsen MM, Bottcher M, Toftegaard NT, Czernin J: Altered regulation of the myocardial microcirculation in young smokers. Cardiology 94:91-98, 2000
21. Campisi R, Czernin J, Schoder H, Sayre JW, Marengo FD, Phelps ME, Schelbert HR: Effects of long-term smoking on myocardial blood flow, coronary vasomotion, and vasodilator capacity. Circulation 98:119-125, 1998
22. Schelbert HR, Wisenberg G, Phelps ME, Gould KL, Henze E, Hoffman EJ, Gomes A, Kuhl DE: Noninvasive assessment of coronary stenoses by myocardial imaging during pharmacologic coronary vasodilation: VI. Detection of coronary artery disease in human beings with intravenous N-13 ammonia and positron computed tomography. Am J Cardiol 49:1197-1207, 1982
23. Pagani M, Malfatto G, Pierini S, Casati R, Masu AM, Poli M, Guzzetti S, Lombardi F, Cerutti S, Malliani A: Spectral analysis of heart rate variability in the assessment of autonomic diabetic neuropathy. J Auton Nerv Syst 23:143-153, 1988
24. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 20:1183-1197, 1997
25. Bottcher M, Czernin J, Sun KT, Phelps ME, Schelbert HR: Effect of caffeine on myocardial blood flow at rest and during pharmacological vasodilation. J Nucl Med 36:2016-2021, 1995
26. Sander M, Chavoshan B, Victor RG: A large blood pressure-raising effect of nitric oxide synthase inhibition in humans. Hypertension 33:937-942, 1999
27. Czernin J, Muller P, Chan S, Brunken RC, Porenta G, Krivokapich J, Chen K, Chan A, Phelps ME, Schelbert HR: Influence of age and hemodynamics on myocardial blood flow and flow reserve. Circulation 88:62-69, 1993
28. Nuyts H, Maes A, Vrolix M, Schiepers C, Schelbert H, Kuhle W, Bormans G, Poppe G, Buxton D, Suetens P, De Geest H, Mortelmans L: Three-dimensional correction for spillover and recovery of myocardial PET images. J Nucl Med 37:767-774, 1996
29. Nuyts J, Suetens P, Oosterlinck A, De Roo M, Mortelmans L: Delineation of ECT images using global constraints and dynamic-programming. IEEE Trans Med Imaging 10:489-498, 1991
30. Nuyts J, Mortelmans L, Van de WF, Djian J, Sambuceti G, Schwaiger M, Touboul P, Maes A: Cardiac phantom measurement validating the methodology for a cardiac multi-centre trial with positron emission tomography. Eur J Nucl Med Mol Imaging 29:1588-1593, 2002
31. Srinivasan M, Herrero P, McGill JB, Bennik J, Heere B, Lesniak D, Davila-Roman VG, Gropler RJ: The effects of plasma insulin and glucose on myocardial blood flow in patients with type 1 diabetes mellitus. J Am Coll Cardiol 46:42-48, 2005
32. Sundell J, Nuutila P, Laine H, Luotolahti M, Kalliokoski K, Raitakari O, Knuuti J: Dose-dependent vasodilating effects of insulin on adenosine-stimulated myocardial blood flow. Diabetes 51:1125-1130, 2002
33. DeFronzo RA, Tobin JD, Andres R: Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223, 1979
34. Egashira K, Inou T, Hirooka Y, Kai H, Sugimachi M, Suzuki S, Kuga T, Urabe Y, Takeshita A: Effects of age on endothelium-dependent vasodilation of resistance coronary artery by acetylcholine in humans. Circulation 88:77-81, 1993
35. Laitinen T, Niskanen L, Geelen G, Lansimies E, Hartikainen J: Age dependency of cardiovascular autonomic responses to head-up tilt in healthy subjects. J Appl Physiol 96:2333-2340, 2004
36. Hogikyan RV, Galecki AT, Halter JB, Supiano MA: Heightened norepinephrine-mediated vasoconstriction in type 2 diabetes. Metabolism 48:1536-1541, 1999
37. Zhao G, Zhang X, Xu X, Wolin MS, Hintze TH: Depressed modulation of oxygen consumption by endogenous nitric oxide in cardiac muscle from diabetic dogs. Am J Physiol Heart Circ Physiol 279:H520-H527, 2000
38. Takamura M, Parent R, Lavallee M: Enhanced contribution of NO to exercise-induced coronary responses after alpha-adrenergic receptor blockade. Am J Physiol Heart Circ Physiol 282:H508-H515, 2002