Frequent mutation of p16CDKN2A exon 1 during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide

Molecular Carcinogenesis

Volumn 46, Issue 2, 2007, Pages 85-90

  Hong, Yun ^a   Yang, Linglan ^a   Li, Chunyang ^a   Xia, Hongbin ^a   Rhodus, Nelson L ^b   Cheng, Bin ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Carcinogenesis; Mutation; p16CDKN2A; Rat; Tongue

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; CYCLIN DEPENDENT KINASE INHIBITOR; DRINKING WATER; GUANINE; PROTEIN P16;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INVASION; CARCINOGENESIS; CONTROLLED STUDY; DYSPLASIA; EXON; FRAMESHIFT MUTATION; GENE AMPLIFICATION; GENE MUTATION; HISTOPATHOLOGY; MALE; MISSENSE MUTATION; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; P16CDKN2A GENE; POINT MUTATION; POLYMERASE CHAIN REACTION; PRECANCER; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS; SPRAGUE DAWLEY RAT; SQUAMOUS CELL CARCINOMA; START CODON; TONGUE CANCER; TUMOR SUPPRESSOR GENE;

4-NITROQUINOLINE-1-OXIDE; ANIMALS; BASE SEQUENCE; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; DNA; EXONS; GENES, P16; MALE; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; TONGUE NEOPLASMS;

RATTUS;

EID: 33847029095     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20197     Document Type: Article

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