메뉴 건너뛰기




Volumn 3, Issue 3, 2006, Pages 357-363

Mechanisms underlying joint pain

Author keywords

[No Author keywords available]

Indexed keywords

1 [5 CHLORO 2 [2 [4 (4 FLUOROBENZYL) 2 METHYL 1 PIPERAZINYL] 2 OXOETHOXY]PHENYL]UREA; ACID SENSING ION CHANNEL; ADALIMUMAB; BRADYKININ; BRADYKININ ANTAGONIST; CANNABINOID RECEPTOR; CAPSAICIN; CELECOXIB; CHEMOKINE RECEPTOR ANTAGONIST; CP 481715; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DRONABINOL; ETANERCEPT; INFLIXIMAB; INTERLEUKIN 1; INTERLEUKIN 6; ION CHANNEL; ION TRANSPORT AFFECTING AGENT; LUMIRACOXIB; METHOTREXATE; MORPHINE; NEUROPEPTIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PSALMOTOXIN; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RESINIFERATOXIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 33847026969     PISSN: 17406765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmec.2006.10.002     Document Type: Review
Times cited : (2)

References (58)
  • 1
    • 0036300405 scopus 로고    scopus 로고
    • Mechanisms of pain in arthritis
    • Schaible H.G., et al. Mechanisms of pain in arthritis. Ann. N.Y. Acad. Sci. 966 (2002) 343-354
    • (2002) Ann. N.Y. Acad. Sci. , vol.966 , pp. 343-354
    • Schaible, H.G.1
  • 2
    • 33744539903 scopus 로고    scopus 로고
    • Osteoarthritis and joint pain
    • [Epub]
    • Kidd B.L. Osteoarthritis and joint pain. Pain 123 (2006) 6-9 [Epub]
    • (2006) Pain , vol.123 , pp. 6-9
    • Kidd, B.L.1
  • 3
    • 0027433726 scopus 로고
    • Afferent and spinal mechanisms of joint pain
    • Schaible H.G., and Grubb B.D. Afferent and spinal mechanisms of joint pain. Pain 55 (1993) 5-54
    • (1993) Pain , vol.55 , pp. 5-54
    • Schaible, H.G.1    Grubb, B.D.2
  • 4
    • 0001414765 scopus 로고    scopus 로고
    • Chemical excitation and sensitization in nociceptors
    • Belmomte C., and Cervero F. (Eds), Oxford University Press
    • Kress M., and Reeh P.W. Chemical excitation and sensitization in nociceptors. In: Belmomte C., and Cervero F. (Eds). Neurobiology of Nociceptors (1996), Oxford University Press 258-297
    • (1996) Neurobiology of Nociceptors , pp. 258-297
    • Kress, M.1    Reeh, P.W.2
  • 5
    • 0031290232 scopus 로고    scopus 로고
    • Anatomy and histology of joint innervation
    • Heppelmann B. Anatomy and histology of joint innervation. J. Peripher. Nerv. Syst. 2 (1997) 5-16
    • (1997) J. Peripher. Nerv. Syst. , vol.2 , pp. 5-16
    • Heppelmann, B.1
  • 6
    • 14644438493 scopus 로고    scopus 로고
    • Physiological characteristics of low-threshold mechanoreceptors in joints, muscle and skin in human subjects
    • Macefield V.G. Physiological characteristics of low-threshold mechanoreceptors in joints, muscle and skin in human subjects. Clin. Exp. Pharmacol. Physiol. 32 (2005) 135-144
    • (2005) Clin. Exp. Pharmacol. Physiol. , vol.32 , pp. 135-144
    • Macefield, V.G.1
  • 7
    • 0020569770 scopus 로고
    • Responses of fine medial articular nerve afferents to passive movements of knee joints
    • Schaible H.G., and Schmidt R.F. Responses of fine medial articular nerve afferents to passive movements of knee joints. J. Neurophysiol. 49 (1983) 1118-1126
    • (1983) J. Neurophysiol. , vol.49 , pp. 1118-1126
    • Schaible, H.G.1    Schmidt, R.F.2
  • 8
    • 0020701023 scopus 로고
    • Activation of groups III and IV sensory units in medial articular nerve by local mechanical stimulation of knee joint
    • Schaible H.G., and Schmidt R.F. Activation of groups III and IV sensory units in medial articular nerve by local mechanical stimulation of knee joint. J. Neurophysiol. 49 (1983) 35-44
    • (1983) J. Neurophysiol. , vol.49 , pp. 35-44
    • Schaible, H.G.1    Schmidt, R.F.2
  • 9
    • 4644264083 scopus 로고    scopus 로고
    • Isolectin B4 binding neurons are not present in the rat knee joint
    • Ivanavicius S.P., et al. Isolectin B4 binding neurons are not present in the rat knee joint. Neuroscience 128 (2004) 555-560
    • (2004) Neuroscience , vol.128 , pp. 555-560
    • Ivanavicius, S.P.1
  • 10
    • 33847026402 scopus 로고    scopus 로고
    • Characteristics of sensory DRG neurons innervating the wrist joint in rats
    • [Epub.]
    • Kuniyoshi K., et al. Characteristics of sensory DRG neurons innervating the wrist joint in rats. Eur. J. Pain (2006) [Epub.]
    • (2006) Eur. J. Pain
    • Kuniyoshi, K.1
  • 11
    • 0037150753 scopus 로고    scopus 로고
    • Inflammation-induced upregulation of neurokinin-1 receptors in rat glabrous skin
    • Carlton S.M., and Coggeshall R.E. Inflammation-induced upregulation of neurokinin-1 receptors in rat glabrous skin. Neurosci. Lett. 326 (2002) 29-32
    • (2002) Neurosci. Lett. , vol.326 , pp. 29-32
    • Carlton, S.M.1    Coggeshall, R.E.2
  • 12
    • 0028584437 scopus 로고
    • Peripheral and central mechanisms of NGF-induced hyperalgesia
    • Lewin G.R., et al. Peripheral and central mechanisms of NGF-induced hyperalgesia. Eur. J. Neurosci. 6 (1994) 1903-1912
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 1903-1912
    • Lewin, G.R.1
  • 13
    • 0037824535 scopus 로고    scopus 로고
    • Central origin of mechanical hyperalgesia
    • Klede M., et al. Central origin of mechanical hyperalgesia. J. Neurophysiol. 90 (2003) 353-359
    • (2003) J. Neurophysiol. , vol.90 , pp. 353-359
    • Klede, M.1
  • 14
    • 0033571905 scopus 로고    scopus 로고
    • Functional attributes discriminating mechano-insensitive and mechano-responsive C nociceptors in human skin
    • Weidner C., et al. Functional attributes discriminating mechano-insensitive and mechano-responsive C nociceptors in human skin. J. Neurosci. 19 (1999) 10184-10190
    • (1999) J. Neurosci. , vol.19 , pp. 10184-10190
    • Weidner, C.1
  • 15
    • 0344559107 scopus 로고    scopus 로고
    • Pathological C fibers in patients with a chronic painful condition
    • Orstavik K., et al. Pathological C fibers in patients with a chronic painful condition. Brain (2003) 567-578
    • (2003) Brain , pp. 567-578
    • Orstavik, K.1
  • 16
    • 33748041976 scopus 로고    scopus 로고
    • Pathophysiology and treatment of pain in joint disease
    • Schaible H.G., et al. Pathophysiology and treatment of pain in joint disease. Adv. Drug Deliv. Revs. 58 (2006) 323-342
    • (2006) Adv. Drug Deliv. Revs. , vol.58 , pp. 323-342
    • Schaible, H.G.1
  • 17
    • 0035693346 scopus 로고    scopus 로고
    • Peripheral analgesic and anti-inflammatory effects of opioids
    • Stein C., et al. Peripheral analgesic and anti-inflammatory effects of opioids. Z. Rheumatol. 60 (2001) 416-424
    • (2001) Z. Rheumatol. , vol.60 , pp. 416-424
    • Stein, C.1
  • 18
    • 0034745609 scopus 로고    scopus 로고
    • Neuropeptide Y changes the excitability of fine afferent units in the rat knee joint
    • Just S., and Heppelmann B. Neuropeptide Y changes the excitability of fine afferent units in the rat knee joint. Br. J. Pharmacol. 132 (2001) 703-708
    • (2001) Br. J. Pharmacol. , vol.132 , pp. 703-708
    • Just, S.1    Heppelmann, B.2
  • 19
    • 0141705322 scopus 로고    scopus 로고
    • Inhibition of neurokinin-1-substance P receptor and prostanoid activity prevents and reverses the development of morphine tolerance in vivo and the morphine-induced increase in CGRP expression in cultured dorsal root ganglion neurons
    • Powell K.J., et al. Inhibition of neurokinin-1-substance P receptor and prostanoid activity prevents and reverses the development of morphine tolerance in vivo and the morphine-induced increase in CGRP expression in cultured dorsal root ganglion neurons. Eur. J. Neurosci. 18 (2003) 1572-1583
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 1572-1583
    • Powell, K.J.1
  • 20
    • 3042645799 scopus 로고    scopus 로고
    • The expression and localization of somatostatin receptors in dorsal root ganglion neurons of normal and monoarthritic rats
    • Bar K.J., et al. The expression and localization of somatostatin receptors in dorsal root ganglion neurons of normal and monoarthritic rats. Neuroscience 127 (2004) 197-206
    • (2004) Neuroscience , vol.127 , pp. 197-206
    • Bar, K.J.1
  • 21
    • 2942575801 scopus 로고    scopus 로고
    • Acid-sensing ion channels (ASICs): new targets for the analgesic effects of non-steroid anti-inflammatory drugs (NSAIDs)
    • Voilley N. Acid-sensing ion channels (ASICs): new targets for the analgesic effects of non-steroid anti-inflammatory drugs (NSAIDs). Curr. Drug Targets Inflamm. Allergy 3 (2004) 71-79
    • (2004) Curr. Drug Targets Inflamm. Allergy , vol.3 , pp. 71-79
    • Voilley, N.1
  • 22
    • 28844471303 scopus 로고    scopus 로고
    • Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors
    • Kobayashi K., et al. Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors. J. Comp. Neurol. 493 (2005) 596-606
    • (2005) J. Comp. Neurol. , vol.493 , pp. 596-606
    • Kobayashi, K.1
  • 23
    • 4644266613 scopus 로고    scopus 로고
    • The role of the vanilloid receptor (TRPV1) in physiology and pathology
    • Nagy I., et al. The role of the vanilloid receptor (TRPV1) in physiology and pathology. Eur. J. Pharmacol. 500 (2004) 351-369
    • (2004) Eur. J. Pharmacol. , vol.500 , pp. 351-369
    • Nagy, I.1
  • 25
    • 32144454172 scopus 로고    scopus 로고
    • The many roles of chemokines and chemokine receptors in inflammation
    • Charo I.F., and Ransohoff R.M. The many roles of chemokines and chemokine receptors in inflammation. New Engl. J. Med. 354 (2006) 610-621
    • (2006) New Engl. J. Med. , vol.354 , pp. 610-621
    • Charo, I.F.1    Ransohoff, R.M.2
  • 26
    • 0028926096 scopus 로고
    • Assessment of cutaneous sensory and autonomic axon reflexes in rheumatoid arthritis
    • Jolliffe V.A., et al. Assessment of cutaneous sensory and autonomic axon reflexes in rheumatoid arthritis. Ann. Rheum. Dis. 54 (1995) 251-255
    • (1995) Ann. Rheum. Dis. , vol.54 , pp. 251-255
    • Jolliffe, V.A.1
  • 27
    • 0025823149 scopus 로고
    • Treatment of arthritis with topical capsaicin: a double-blind trial
    • Deal C.L. Treatment of arthritis with topical capsaicin: a double-blind trial. Clin. Ther. 13 (1991) 383-395
    • (1991) Clin. Ther. , vol.13 , pp. 383-395
    • Deal, C.L.1
  • 28
    • 0034489458 scopus 로고    scopus 로고
    • The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis: a randomized, double blind, placebo controlled study
    • McCleane G. The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis: a randomized, double blind, placebo controlled study. Eur. J. Pain. 4 (2000) 355-360
    • (2000) Eur. J. Pain. , vol.4 , pp. 355-360
    • McCleane, G.1
  • 29
    • 0035875701 scopus 로고    scopus 로고
    • Capsaicin responses in heat-sensitive and heat-insensitive A-fiber nociceptors
    • Ringkamp M., et al. Capsaicin responses in heat-sensitive and heat-insensitive A-fiber nociceptors. J. Neurosci. 21 (2001) 4460-4468
    • (2001) J. Neurosci. , vol.21 , pp. 4460-4468
    • Ringkamp, M.1
  • 30
    • 0028861501 scopus 로고
    • Novel classes of responsive and unresponsive C nociceptors in human skin
    • Schmidt R., et al. Novel classes of responsive and unresponsive C nociceptors in human skin. J. Neurosci. 15 (1995) 333-341
    • (1995) J. Neurosci. , vol.15 , pp. 333-341
    • Schmidt, R.1
  • 31
    • 0029879057 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide is involved in the spinal processing of mechanosensory input from the rat's knee joint and in the generation and maintenance of hyperexcitability of dorsal horn neurons during development of acute inflammation
    • Neugebauer V., et al. Calcitonin gene-related peptide is involved in the spinal processing of mechanosensory input from the rat's knee joint and in the generation and maintenance of hyperexcitability of dorsal horn neurons during development of acute inflammation. Neuroscience 71 (1996) 1095-1109
    • (1996) Neuroscience , vol.71 , pp. 1095-1109
    • Neugebauer, V.1
  • 32
    • 0028959583 scopus 로고
    • Inveolvement of substance P and neurokinin-1 reeceptors in the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint
    • Neugebauer V., et al. Inveolvement of substance P and neurokinin-1 reeceptors in the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint. J. Neurophysiol. 73 (1995) 1574-1583
    • (1995) J. Neurophysiol. , vol.73 , pp. 1574-1583
    • Neugebauer, V.1
  • 33
    • 0027933184 scopus 로고
    • Modulation of spinal excitability: Cooperation between neurokinin and excitatory amino acid transmitters
    • Urban L., et al. Modulation of spinal excitability: Cooperation between neurokinin and excitatory amino acid transmitters. Trends Neurosci. 17 (1994) 432-438
    • (1994) Trends Neurosci. , vol.17 , pp. 432-438
    • Urban, L.1
  • 34
    • 0037006122 scopus 로고    scopus 로고
    • Efficacy of rofecoxib, celecoxib, and acetaminophen in osteoarthritis of the knee: a randomized trial
    • Geba G.P., et al. Efficacy of rofecoxib, celecoxib, and acetaminophen in osteoarthritis of the knee: a randomized trial. J. Am. Med. Assoc. 287 (2002) 64-71
    • (2002) J. Am. Med. Assoc. , vol.287 , pp. 64-71
    • Geba, G.P.1
  • 35
    • 0034782648 scopus 로고    scopus 로고
    • Analgesia and COX-2 inhibition
    • Dionne R.A., et al. Analgesia and COX-2 inhibition. Clin. Exp. Rheumatol. 19 (2001) 63-70
    • (2001) Clin. Exp. Rheumatol. , vol.19 , pp. 63-70
    • Dionne, R.A.1
  • 36
    • 0031473814 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production
    • Zhang Y., et al. Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production. J. Phamacol. Exp. Ther. 283 (1997) 1069-1075
    • (1997) J. Phamacol. Exp. Ther. , vol.283 , pp. 1069-1075
    • Zhang, Y.1
  • 37
    • 0029761647 scopus 로고    scopus 로고
    • PGE2 modulates the tetrodotoxin-resistant sodium current in neonatal rat dorsal root ganglion neurons via the cyclic AMP-protein kinase A cascade
    • England S., et al. PGE2 modulates the tetrodotoxin-resistant sodium current in neonatal rat dorsal root ganglion neurons via the cyclic AMP-protein kinase A cascade. J. Physiol. (Lond) 495 (1996) 429-440
    • (1996) J. Physiol. (Lond) , vol.495 , pp. 429-440
    • England, S.1
  • 38
    • 1842514976 scopus 로고    scopus 로고
    • VEGF release is associated with hypoxia in inflammatory arthritis
    • Taylor P.C., et al. VEGF release is associated with hypoxia in inflammatory arthritis. Arthritis Rheum. 43 Suppl. 9 (2000) S296
    • (2000) Arthritis Rheum. , vol.43 , Issue.SUPPL. 9
    • Taylor, P.C.1
  • 39
    • 33749536383 scopus 로고    scopus 로고
    • Osteoclasts play a part in pain due to the inflammation adjacent to bone
    • [Epub ahead of print]
    • Nagae M., et al. Osteoclasts play a part in pain due to the inflammation adjacent to bone. Bone (2006 Jun 10) [Epub ahead of print]
    • (2006) Bone
    • Nagae, M.1
  • 40
    • 20444375419 scopus 로고    scopus 로고
    • The clinical potential of chemokine receptor antagonists
    • Ribeiro S., and Horuk R. The clinical potential of chemokine receptor antagonists. Pharmacol. and Therap. 107 (2005) 44-58
    • (2005) Pharmacol. and Therap. , vol.107 , pp. 44-58
    • Ribeiro, S.1    Horuk, R.2
  • 41
    • 0242409906 scopus 로고    scopus 로고
    • Tumor necrosis factor-α: Molecular and cellular mechanisms in skeletal pathology
    • Nanes M.S. Tumor necrosis factor-α: Molecular and cellular mechanisms in skeletal pathology. Gene 321 (2003) 1-15
    • (2003) Gene , vol.321 , pp. 1-15
    • Nanes, M.S.1
  • 42
    • 0142156483 scopus 로고    scopus 로고
    • Comparison of the efficacy of the tumor necrosis alpha blocking agents adalimumab, etanercept and infliximab when added to methotrexate in patients with active rheumatoid arthritis
    • Hochberg M.C., et al. Comparison of the efficacy of the tumor necrosis alpha blocking agents adalimumab, etanercept and infliximab when added to methotrexate in patients with active rheumatoid arthritis. Ann. Rheum. Dis. suppl. 2 (2003) ii13-ii16
    • (2003) Ann. Rheum. Dis. , Issue.SUPPL. 2
    • Hochberg, M.C.1
  • 43
    • 14044274118 scopus 로고    scopus 로고
    • Excitatry and modulatory effects of inflammatory cytokines and neurotrophins on mechanosensitive group IV muscle afferents in the rat
    • Hoheisel U., et al. Excitatry and modulatory effects of inflammatory cytokines and neurotrophins on mechanosensitive group IV muscle afferents in the rat. Pain 114 (2005) 168-176
    • (2005) Pain , vol.114 , pp. 168-176
    • Hoheisel, U.1
  • 44
    • 0035932121 scopus 로고    scopus 로고
    • Interleukin-1β-mediated induction of COX-2 in the CNS contributes to inflammatory pain hypersensitivity
    • Samad T.A., et al. Interleukin-1β-mediated induction of COX-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410 (2001) 471-475
    • (2001) Nature , vol.410 , pp. 471-475
    • Samad, T.A.1
  • 45
    • 0345701254 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons
    • Schaefers M., et al. Tumor necrosis factor-α induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons. J. Neurosci. 23 (2003) 2517-2521
    • (2003) J. Neurosci. , vol.23 , pp. 2517-2521
    • Schaefers, M.1
  • 46
    • 0030920014 scopus 로고    scopus 로고
    • Bradykinin-induced knee joint incapacitation involves bradykinin B2 receptor mediated hyperalgesia and bradykinin B1 receptor mediated nociception
    • Tonussi C.R., and Ferreira S.H. Bradykinin-induced knee joint incapacitation involves bradykinin B2 receptor mediated hyperalgesia and bradykinin B1 receptor mediated nociception. Eur. J. Pharmacol. 326 (1997) 61-65
    • (1997) Eur. J. Pharmacol. , vol.326 , pp. 61-65
    • Tonussi, C.R.1    Ferreira, S.H.2
  • 47
    • 0028172370 scopus 로고
    • The role of bradykinin B1 receptors in the maintenance of intra articular plasma extravasation in chronic antigen-induced arthritis
    • Cruwys S.C., et al. The role of bradykinin B1 receptors in the maintenance of intra articular plasma extravasation in chronic antigen-induced arthritis. Br. J. Pharmacol. 113 (1994) 940-944
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 940-944
    • Cruwys, S.C.1
  • 48
    • 33745819616 scopus 로고    scopus 로고
    • Biological therapies for inflammatory bowel disease: research drives clinics
    • Danese S., et al. Biological therapies for inflammatory bowel disease: research drives clinics. Mini Revs. In Med. Chem. 6 (2006) 771-784
    • (2006) Mini Revs. In Med. Chem. , vol.6 , pp. 771-784
    • Danese, S.1
  • 49
    • 0036845130 scopus 로고    scopus 로고
    • Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis: Extension phase of a randomized, double-blind, placebo-controlled trial
    • Nuki G., et al. Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis: Extension phase of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 46 (2002) 2838-2846
    • (2002) Arthritis Rheum. , vol.46 , pp. 2838-2846
    • Nuki, G.1
  • 50
    • 4344645732 scopus 로고    scopus 로고
    • Pain and osteoarthritis: new drugs and mechanisms
    • Hinz B., and Brune K. Pain and osteoarthritis: new drugs and mechanisms. Curr. Opin. Rheumatol. 16 (2004) 628-633
    • (2004) Curr. Opin. Rheumatol. , vol.16 , pp. 628-633
    • Hinz, B.1    Brune, K.2
  • 51
    • 0242552926 scopus 로고    scopus 로고
    • Comparing the efficacy of cyclooxygenase 2-specific inhibitors in treating osteoarthritis: appropriate trial design considerations and results of a randomized, placebo-controlled trial
    • Gibofsky A., et al. Comparing the efficacy of cyclooxygenase 2-specific inhibitors in treating osteoarthritis: appropriate trial design considerations and results of a randomized, placebo-controlled trial. Arthritis Rheum. 48 (2003) 3102-3111
    • (2003) Arthritis Rheum. , vol.48 , pp. 3102-3111
    • Gibofsky, A.1
  • 52
    • 28944454515 scopus 로고    scopus 로고
    • The use of opioids in the treatment of osteoarthritis: when, why, and how?
    • Goodwin J.L., et al. The use of opioids in the treatment of osteoarthritis: when, why, and how?. Curr. Pain Headache Rep. 9 (2005) 390-398
    • (2005) Curr. Pain Headache Rep. , vol.9 , pp. 390-398
    • Goodwin, J.L.1
  • 53
    • 33745617106 scopus 로고    scopus 로고
    • Microsomal prostaglandin E synthase-1, ephrins, and ephrin kinases as suspected therapeutic targets in arthritis: exposed by "criminal profiling"
    • Romanovsky A.A., et al. Microsomal prostaglandin E synthase-1, ephrins, and ephrin kinases as suspected therapeutic targets in arthritis: exposed by "criminal profiling". Ann. N. Y. Acad. Sci. 1069 (2006) 183-194
    • (2006) Ann. N. Y. Acad. Sci. , vol.1069 , pp. 183-194
    • Romanovsky, A.A.1
  • 54
    • 33745726257 scopus 로고    scopus 로고
    • TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications
    • [Epub 2006 May 24]
    • Avelino A., and Cruz F. TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. Naunyn Schmiedebergs Arch. Pharmacol. 373 (2006) 287-299 [Epub 2006 May 24]
    • (2006) Naunyn Schmiedebergs Arch. Pharmacol. , vol.373 , pp. 287-299
    • Avelino, A.1    Cruz, F.2
  • 55
    • 17144435064 scopus 로고    scopus 로고
    • CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases
    • Gladue R.P., et al. CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases. J. Biol. Chem. 278 (2003) 40473-40480
    • (2003) J. Biol. Chem. , vol.278 , pp. 40473-40480
    • Gladue, R.P.1
  • 56
    • 0033363999 scopus 로고    scopus 로고
    • The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
    • Akopian A.N., et al. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat. Neurosci. 2 (1999) 541-548
    • (1999) Nat. Neurosci. , vol.2 , pp. 541-548
    • Akopian, A.N.1
  • 57
    • 33746592402 scopus 로고    scopus 로고
    • Advances in the development of bradykinin receptor ligands
    • Fortin J.P., and Marceau F.O. Advances in the development of bradykinin receptor ligands. Curr. Top. Med. Chem. 6 (2006) 1353-1363
    • (2006) Curr. Top. Med. Chem. , vol.6 , pp. 1353-1363
    • Fortin, J.P.1    Marceau, F.O.2
  • 58
    • 4043096916 scopus 로고    scopus 로고
    • Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial
    • Svendsen K.B., et al. Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial. Br. Med. J. 329 (2004) 253
    • (2004) Br. Med. J. , vol.329 , pp. 253
    • Svendsen, K.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.