Comparative analysis of virulence determinants and mass spectral profiles of Finnish and Lithuanian endodontic Enterococcus faecalis isolates

Oral Microbiology and Immunology

Volumn 22, Issue 2, 2007, Pages 87-94

  Reynaud Af Geijersstam, A ^a,e   Culak, R ^b   Molenaar, L ^b   Chattaway, M ^b   Roslie E ^a   Peciuliene, V ^c   Haapasalo, M ^d   Shah, H N ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

^c VILNIUS UNIVERSITY   (Lithuania)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e NONE   (Sweden)

Author keywords

Endodontic infections; Enterococcus faecalis; MALDI TOF; SELDI TOF; Virulence determinants

Indexed keywords

BACTERIAL PROTEIN; CYTOLYSIN; DALFOPRISTIN PLUS QUINUPRISTIN; GELATINASE; PROTEIN ACE; PROTEIN EFAA; PROTEIN ESP; PROTEIN GELE; UNCLASSIFIED DRUG;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; COMPARATIVE STUDY; DEVICE; ENTEROCOCCUS FAECALIS; EXTRACTION; GENETIC ANALYSIS; HYDROLYSIS; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUTH FLORA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; STATISTICAL ANALYSIS; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; TOOTH ROOT CANAL;

ANTI-BACTERIAL AGENTS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CARRIER PROTEINS; DENTAL PULP CAVITY; ENTEROCOCCUS FAECALIS; EPIDEMIOLOGY, MOLECULAR; FINLAND; GELATINASES; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; LITHUANIA; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; PERIAPICAL PERIODONTITIS; PORE FORMING CYTOTOXIC PROTEINS; PROTEIN ARRAY ANALYSIS; PROTEOME; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VIRGINIAMYCIN; VIRULENCE FACTORS;

EID: 33847020697     PISSN: 09020055     EISSN: 1399302X     Source Type: Journal    
DOI: 10.1111/j.1399-302X.2007.00327.x     Document Type: Article

References (55)

1. Aitchison EJ, Lambert PA, Smith EG, Farrell ID. Serodiagnosis of Streptococcus faecalis endocarditis by immunoblotting of surface protein antigens. J Clin Microbiol 1987: 25: 211-215.
2. Bittencourt de Marques E, Suzart S. Occurrence of virulence-associated genes in clinical Enterococcus faecalis strains isolated in Londrina, Brazil. J Med Microbiol 2004: 53: 1069-1073.
3. Bogie CP, Hancock LE, Gilmore MS. The Enterococcus faecalis cytolysin determinant and its relationship to those encoding lantibiotics. Dev Biol Stand 1995: 85: 627-634.
4. Booth MC, Bogie CP, Sahl HG, Siezen RJ, Hatter KL, Gilmore MS. Structural analysis and proteolytic activation of Enterococcus faecalis cytolysin, a novel lantibiotic. Mol Microbiol 1996: 21: 1175-1184.
5. Chow JW, Thal LA, Perri MB et al. Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis. Antimicrob Agents Chemother 1993: 37: 2474-2477.
6. Coburn PS, Gilmore MS. The Enterococcus faecalis cytolysin: a novel toxin active against eukaryotic and prokaryotic cells. Cell Microbiol 2003: 5: 661-669.
7. Coburn PS, Pillar CM, Jett BD, Haas W, Gilmore MS. Enterococcus faecalis senses target cells and in response expresses cytolysin. Science 2004: 306: 2270-2272.
8. Coque TM, Patterson JE, Steckelberg JM, Murray BE. Incidence of hemolysin, gelatinase, and aggregation substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons. J Infect Dis 1995: 171: 1223-1229.
9. Cwikla SJ, Belanger M, Giguere S, Progulske-Fox A, Vertucci FJ. Dentinal tubule disinfection using three calcium hydroxide formulations. J Endod 2005: 31: 50-52.
10. Dina J, Malbruny B, Leclercq R. Nonsense mutations in the lsa-like gene in Enterococcus faecalis isolates susceptible to lincosamides and streptogramins A. Antimicrob Agents Chemother 2003: 47: 2307-2309.
11. Distel JW, Hatton JF, Gillespie MJ. Biofilm formation in medicated root canals. J Endod 2002: 28: 689-693.
12. Duh RW, Singh KV, Malathum K, Murray BE. In vitro activity of 19 antimicrobial agents against enterococci from healthy subjects and hospitalized patients and use of an ace gene probe from Enterococcus faecalis for species identification. Microb Drug Resist 2001: 7: 39-46.
13. Duprè I, Zanetti S, Schito AM, Fadda G, Sechi LA. Incidence of virulence determinants in clinical Enterococcus faecium and Enterococcus faecalis isolates collected in Sardinia (Italy). J Med Microbiol 2003: 52: 491-498.
14. Eaton TJ, Gasson MJ. Molecular screening of Enterococcus virulence determinants and potential for genetic exchange between food and medical isolates. Appl Environ Microbiol 2001: 67: 1628-1635.
15. Facklam RR, Carvalho MG, Teixeira LM, History, taxonomy, biochemical characteristics, and antibiotic susceptibility testing of enterococci. In: Gilmore MS, ed. The enterococci, pathogenesis, molecular biology, and antibiotic resistance. Washington, DC: ASM Press, 2002: 1-54.
16. Fouad AF, Zerella J, Barry J, Spångberg LS. Molecular detection of Enterococcus species in root canals of therapy-resistant endodontic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005: 99: 112-118.
17. Ganeshkumar N, Song M, McBride BC. Cloning of a Streptococcus sanguis adhesin which mediates binding to saliva-coated hydroxyapatite. Infect Immun 1988: 56: 1150-1157.
18. Gilmore MS, Enterococcus faecalis hemolysin/bacteriocin. In: Dunny GM, Cleary PP, McKay LL, eds. Genetics and molecular biology of streptococci, lactobacilli and enterococci. Washington, DC: American Society for Microbiology, 1991: 206-213.
19. Gilmore MS, Coburn PS, Nallapareddy SR, Murray BE. Enterococcal virulence. In: Gilmore MS, ed. The enterococci, pathogenesis, molecular biology, and antibiotic resistance. Washington, DC: ASM Press, 2002: 301-354.
20. Hancock LE, Perego M. The Enterococcus faecalis fsr two-component system controls biofilm development through production of gelatinase. J Bacteriol 2004: 186: 5629-5639.
21. Hancock HH, III, Sigurdsson A, Trope M, Moiseiwitsch J. Bacteria isolated after unsuccessful endodontic treatment in a North American population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001: 91: 579-586.
22. Hubble TS, Hatton JF, Nallapareddy SR, Murray BE, Gillespie MJ. Influence of Enterococcus faecalis proteases and the collagen-binding protein, Ace, on adhesion to dentin. Oral Microbiol Immunol 2003: 18: 121-126.
23. Huycke MM, Gilmore MS. Frequency of aggregation substance and cytolysin genes among enterococcal endocarditis isolates. Plasmid 1995: 34: 152-156.
24. Huycke MM, Spiegel CA, Gilmore MS. Bacteremia caused by hemolytic, high-level gentamicin-resistant Enterococcus faecalis. Antimicrob Agents Chemother 1991: 35: 1626-1634.
25. Ike Y, Clewell DB, Segarra RA, Gilmore MS. Genetic analysis of the pAD1 hemolysin/bacteriocin determinant in Enterococcus faecalis: Tn917 insertional mutagenesis and cloning. J Bacteriol 1990: 172: 155-163.
26. Ike Y, Hashimoto H, Clewell DB. Hemolysin of Streptococcus faecalis subspecies zymogenes contributes to virulence in mice. Infect Immun 1984: 45: 528-530.
27. Jett BD, Huycke MM, Gilmore MS. Virulence of enterococci. Clin Microbiol Rev 1994: 7: 462-478.
28. Keys CJ, Dare DJ, Sutton H et al. Compilation of a MALDI-TOF mass spectral database for the rapid screening and characterisation of bacteria implicated in human infectious diseases. Infect Genet Evol 2004: 4: 221-242.
29. Lowe AM, Lambert PA, Smith AW. Cloning of an Enterococcus faecalis endocarditis antigen: homology with adhesins from some oral streptococci. Infect Immun 1995: 63: 703-706.
30. Mejare B. Streptococcus faecalis and Streptococcus faecium in infected dental root canals at filling and their susceptibility to azidocillin and some comparable antibiotics. Odontol Rev 1975: 26: 193-204.
31. Mohamed JA, Huang W, Nallapareddy SR, Teng F, Murray BE. Influence of origin of isolates, especially endocarditis isolates, and various genes on biofilm formation by Enterococcus faecalis. Infect Immun 2004: 72: 3658-3663.
32. Molander A, Reit C, Dahlén G, Kvist T. Microbiological status of root-filled teeth with apical periodontitis. Int Endod J 1998: 31: 1-7.
33. Nallapareddy SR, Singh KV, Duh RW, Weinstock GM, Murray BE. Diversity of ace, a gene encoding a microbial surface component recognizing adhesive matrix molecules, from different strains of Enterococcus faecalis and evidence for production of Ace during human infections. Infect Immun 2000: 68: 5210-5217.
34. Peciuliene V, Balciuniene I, Eriksen HM, Haapasalo M. Isolation of Enterococcus faecalis in previously root-filled canals in a Lithuanian population. J Endod 2000: 26: 593-595.
35. Peciuliene V, Reynaud AH, Balciuniene I, Haapasalo M. Isolation of yeasts and enteric bacteria in root-filled teeth with chronic apical periodontitis. Int Endod J 2001: 34: 429-434.
36. Portenier I, Waltimo TMT, Haapasalo M. Enterococcus faecalis - the root canal survivor and 'star' in post-treatment disease. Endod Topics 2003: 6: 135-159.
37. Reynaud af Geijersstam AH, Ellington MJ, Warner M, Woodford N, Haapasalo M. Antimicrobial susceptibility and molecular analysis of Enterococcus faecalis originating from endodontic infections in Finland and Lithuania. Oral Microbiol Immunol 2006: 21: 164-168.
38. Rich RL, Kreikemeyer B, Owens RT et al. Ace is a collagen-binding MSCRAMM from Enterococcus faecalis. J Biol Chem 1999: 274: 26939-26945.
39. Rôças IN, Siqueira JF, Jr, Santos KR. Association of Enterococcus faecalis with different forms of periradicular diseases. J Endod 2004: 30: 315-320.
40. Sedgley CM, Molander A, Flannagan SE et al. Virulence, phenotype and genotype characteristics of endodontic Enterococcus spp. Oral Microbiol Immunol 2005: 20: 10-19.
41. Shankar N, Baghdayan AS, Gilmore MS. Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis. Nature 2002: 417: 746-750.
42. Shankar V, Baghdayan AS, Huycke MM, Lindahl G, Gilmore MS. Infection-derived Enterococcus faecalis strains are enriched in esp, a gene encoding a novel surface protein. Infect Immun 1999: 67: 193-200.
43. Shankar N, Lockatell CV, Baghdayan AS, Drachenberg C, Gilmore MS, Johnson DE. Role of Enterococcus faecalis surface protein Esp in the pathogenesis of ascending urinary tract infection. Infect Immun 2001: 69: 4366-4372.
44. Singh KV, Coque TM, Weinstock GM, Murray BE. In vivo testing of an Enterococcus faecalis efaA mutant and use of efaA homologs for species identification. FEMS Immunol Med Microbiol 1998: 21: 323-331.
45. Singh KV, Qin X, Weinstock GM, Murray BE. Generation and testing of mutants of Enterococcus faecalis in a mouse peritonitis model. J Infect Dis 1998: 178: 1416-1420.
46. Singh KV, Weinstock GM, Murray BE. An Enterococcus faecalis ABC homologue (Lsa) is required for the resistance of this species to clindamycin and quinupristindalfopristin. Antimicrob Agents Chemother 2002: 46: 1845-1850.
47. Siqueira JF, Jr, Rôças IN. Polymerase chain reaction-based analysis of microorganisms associated with failed endodontic treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004: 97: 85-94.
48. Sirén EK, Haapasalo MP, Ranta K, Salmi P, Kerosuo EN. Microbiological findings and clinical treatment procedures in endodontic cases selected for microbiological investigation. Int Endod J 1997: 30: 91-95.
49. Sunde PT, Olsen I, Debelian GJ, Tronstad L. Microbiota of periapical lesions refractory to endodontic therapy. J Endod 2002: 28: 304-310.
50. Takemura N, Noiri Y, Ehara A, Kawahara T, Noguchi N, Ebisu S. Single species biofilm-forming ability of root canal isolates on gutta-percha points. Eur J Oral Sci 2004: 112: 523-529.
51. Tettelin H, Saunders NJ, Heidelberg J et al. Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science 2000: 287: 1809-1815.
52. Toledo-Arana A, Valle J, Solano C et al. The enterococcal surface protein, Esp, is involved in Enterococcus faecalis biofilm formation. Appl Environ Microbiol 2001: 67: 4538-4545.
53. Vergis EN, Shankar N, Chow JW et al. Association between the presence of enterococcal virulence factors gelatinase, hemolysin, and enterococcal surface protein and mortality among patients with bacteremia due to Enterococcus faecalis. Clin Infect Dis 2002: 35: 570-575.
54. Willems RJ, Homan W, Top J et al. Variant esp gene as a marker of a distinct genetic lineage of vancomycin-resistant Enterococcus faecium spreading in hospitals. Lancet 2001: 357: 853-855.
55. Woodford N, Soltani M, Hardy KJ. Frequency of esp in Enterococcus faecium isolates. Lancet 2001: 358: 584.