Association between the presence of enterococcal virulence factors gelatinase, hemolysin, and enterococcal surface protein and mortality among patients with bacteremia due to Enterococcus faecalis

Clinical Infectious Diseases

Volumn 35, Issue 5, 2002, Pages 570-575

  Vergis, Emanuel N ^a   Shankar, Nathan ^b   Chow, Joseph W ^c   Hayden, Mary K ^d   Snydman, David R ^e   Zervos, Marcus J ^f   Linden, Peter K ^a   Wagener, Marilyn M ^a   Muder, Robert R ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c RUSH MEDICAL COLLEGE   (United States)

^d WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f WILLIAM BEAUMONT HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENTEROCOCCAL SURFACE PROTEIN; GELATINASE; HEMOLYSIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ADOLESCENT; ADULT; AGED; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTEREMIA; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; BLADDER; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTEREMIA; BACTERIAL PROTEINS; DRUG RESISTANCE; ENTEROCOCCUS FAECALIS; FEMALE; GELATINASES; HEMOLYSIN PROTEINS; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MORTALITY; VIRULENCE;

EID: 0036720773     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/341977     Document Type: Article

References (27)

1. Vancomycin-resistant enterococci
2. Incidence of hemolysin, gelatinase, and aggregation substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons
3. The pathogenicity of enterococci
4. The hemolysin/bacteriocin produced by enterococci is a marker of pathogenicity
5. Contribution of the pAD1-encoded cytolysin to the severity of experimental Enterococcus faecalis endophthalmitis
6. Hemolysin of Streptococcus faecalis subspecied zymogenes contributes to virulence in mice
7. Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis
8. High incidence of hemolysin production by Enterococcus (Streptococcus) faecalis strains associated with human parenteral infections
9. Aggregation substance of Enterococcus faecalis mediates adhesion to cultured renal tubular cells
10. Experimental endocarditis in rabbits. 3. Significance of the proteolytic capacity of the infecting strains of Streptococcus faecalis
11. Infection-derived Enterococcus faecalis strains are enriched in esp, a gene encoding a novel surface protein
12. Role of Enterococcus faecalis surface protein Esp in the pathogenesis of ascending urinary tract infection
13. Bacteremia caused by hemolytic, high-level gentamicin-resistant Enterococcus faecalis
14. Determinants of vancomycin resistance and mortality rates in enterococcal bacteremia
15. Enterococcal bacteremia: Clinical features, the risk of endocarditis, and management
16. Enterobacter bacteremia: Clinical features and emergence of antibiotic resistance during therapy
17. Antibiotic therapy for Pseudomonas aeruginosa bacteremia: Outcome correlations in a prospective study of 200 patients
18. Prospective observational study of Klebsiella bacteremia in 230 patients: Outcome for antibiotic combinations versus monotherapy
19. Antimicrobial resistance and clinical outcome of Bacteroides bacteremia: Findings of a multicenter prospective observational trial
20. Disparate findings on the role of virulence factors of Enterococcus faecalis in mouse and rat models of peritonitis
21. A hemolysin-encoding plasmid contributes to bacterial virulence in experimental Enterococcus faecalis endophthalmitis
22. Aggregation and binding substances enhance pathogenicity in rabbit models of Enterococcus faecalis endocarditis
23. Enterococcus faecalis localization in experimental endophthalmitis: Role of plasmid-encoded aggregation substance
24. Ace is a collagen-binding MSCRAMM from Enterococcus faecalis
25. Diversity of ace, a gene encoding a microbial surface component recognizing adhesive matrix molecules, from different strains of Enterococcus faecalis and evidence for production of Ace during human infections
26. Enterococcus faecalis adhesion, Ace, mediates attachment to extracellular matrix proteins collagen type IV and laminin as well as collagen type I