Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

Biochemical Journal

Volumn 402, Issue 1, 2007, Pages 43-49

  Comini, Marcelo A ^a   Krauth Siegel, R Luise ^a   Flohé, Leopold ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Molisa GmbH   (Germany)

Author keywords

African trypanosome; Hydroperoxide metabolism; Thioredoxin; Trypanosoma brucei; Trypanothione; Tryparedoxin

Indexed keywords

ANTIOXIDATIVE DEFENSE; HYDROPEROXIDE METABOLISM; TRYPANOSOMA BRUCEI; TRYPANOSOMES; TRYPANOTHIONE; TRYPAREDOXIN;

DETOXIFICATION; DNA; HYDROGEN PEROXIDE; METABOLISM; OXIDATION; PROTEINS;

LIVING SYSTEMS STUDIES;

GLUTATHIONE; HYDROPEROXIDE; OXIDOREDUCTASE; THIOREDOXIN; TRYPANOTHIONE; TRYPAREDOXIN; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; DETOXIFICATION; DNA REPLICATION; DNA SYNTHESIS; FLAGELLATE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FOLDING; RNA INTERFERENCE; TRYPANOSOMA; TSETSE FLY;

ANIMALS; CELL LINE; CYTOSOL; GLUTATHIONE; HYDROGEN PEROXIDE; MITOCHONDRIA; MODELS, BIOLOGICAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN ISOFORMS; PROTOZOAN PROTEINS; RNA INTERFERENCE; THIOREDOXIN; TIME FACTORS; TRYPANOSOMA BRUCEI BRUCEI;

GLOSSINA (GENUS); KINETOPLASTIDA; MAMMALIA; TRYPANOSOMA BRUCEI;

EID: 33846963220     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20061341     Document Type: Article

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