Ac2-DPD, the bis-(O)-acetylated derivative of 4,5-dihydroxy-2,3-pentanedione (DPD) is a convenient stable precursor of bacterial quorum sensing autoinducer AI-2

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 5, 2007, Pages 1428-1431

  Frezza, Marine ^a   Soulère, Laurent ^a   Balestrino, Damien ^b   Gohar, Michel ^c   Deshayes, Christian ^a   Queneau, Yves ^a   Forestier, Christiane ^b   Doutheau, Alain ^a  

^a UNIVERSITÉ LYON 1   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c CNRS   (France)

Author keywords

AI 2; Autoinducer; DPD; Quorum sensing

Indexed keywords

4,5 DIHYDROXY 2,3 PENTANEDIONE; ACETIC ACID DERIVATIVE; ACETYLACETONE; BETA GALACTOSIDASE; UNCLASSIFIED DRUG; 4,5-DIHYDROXY-2,3-PENTANEDIONE; DRUG DERIVATIVE; HOMOSERINE; LACTONE; N OCTANOYLHOMOSERINE LACTONE; N-OCTANOYLHOMOSERINE LACTONE; PENTANE;

ACETYLATION; ARTICLE; BACILLUS CEREUS; BIOFILM; BIOLUMINESCENCE; CELL COMMUNICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STABILITY; ENZYME ACTIVITY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IC 50; NONHUMAN; QUORUM SENSING; SALMONELLA ENTERICA; VIBRIO HARVEYI; CHEMISTRY; DRUG EFFECT; HYDROLYSIS; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

BACILLUS CEREUS; BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA; SALMONELLA ENTERICA; VIBRIO HARVEYI;

ACETYLATION; DRUG STABILITY; HOMOSERINE; HYDROLYSIS; LACTONES; PENTANES; QUORUM SENSING; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846948980     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.11.076     Document Type: Article

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