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For full data, see Supporting Information
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For full data, see Supporting Information.
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11
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0026623543
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Isopropylidene glyceraldehyde can be generated as either enantiomer in a few steps, but it is quite volatile and dimerizes readily. These drawbacks have led to the development of other protecting groups for glyceraldehyde. (a) For a general discussion, see: Schmid, C. R.; Bradley, D. A. Synthesis 1992, 587-590. (b) For discussion and elaborate solutions, see: Michel, P.; Ley, S. V. Synthesis 2003, 10, 1598-1602. Aube, J.; Mossman, C. J.; Dickey, S. Tetrahedron 1992, 48, 45, 9819-9826. (c) First reported by: Grauert, M.; Schollkopf, U. Liebigs, Ann. Chem. 1985, 1817-1824
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Isopropylidene glyceraldehyde can be generated as either enantiomer in a few steps, but it is quite volatile and dimerizes readily. These drawbacks have led to the development of other protecting groups for glyceraldehyde. (a) For a general discussion, see: Schmid, C. R.; Bradley, D. A. Synthesis 1992, 587-590. (b) For discussion and elaborate solutions, see: Michel, P.; Ley, S. V. Synthesis 2003, 10, 1598-1602. Aube, J.; Mossman, C. J.; Dickey, S. Tetrahedron 1992, 48, 45, 9819-9826. (c) First reported by: Grauert, M.; Schollkopf, U. Liebigs, Ann. Chem. 1985, 1817-1824
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