-
1
-
-
0022802258
-
The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (Prp)
-
Hope J, Morton LJ, Farquhar CF, Multhaup G, Beyreuther K & Kimberlin RH (1986) The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (Prp). EMBO J 5, 2591-2597.
-
(1986)
EMBO J
, vol.5
, pp. 2591-2597
-
-
Hope, J.1
Morton, L.J.2
Farquhar, C.F.3
Multhaup, G.4
Beyreuther, K.5
Kimberlin, R.H.6
-
2
-
-
0040393220
-
Separation and properties of cellular and scrapie prion proteins
-
Meyer RK, McKinley MP, Bowman KA, Braunfeld MB, Barry RA & Prusiner SB (1986) Separation and properties of cellular and scrapie prion proteins. Proc Natl Acad Sci USA 83, 2310-2314.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 2310-2314
-
-
Meyer, R.K.1
McKinley, M.P.2
Bowman, K.A.3
Braunfeld, M.B.4
Barry, R.A.5
Prusiner, S.B.6
-
3
-
-
0022005315
-
A cellular gene encodes scrapie PrP 27-30 protein
-
Oesch B, Westaway D, Walchli M, McKinley MP, Kent SB, Aebersold R, Barry RA, Tempst P, Teplow DB, Hood LE, et al. (1985) A cellular gene encodes scrapie PrP 27-30 protein. Cell 40, 735-746.
-
(1985)
Cell
, vol.40
, pp. 735-746
-
-
Oesch, B.1
Westaway, D.2
Walchli, M.3
McKinley, M.P.4
Kent, S.B.5
Aebersold, R.6
Barry, R.A.7
Tempst, P.8
Teplow, D.B.9
Hood, L.E.10
-
4
-
-
0027195933
-
Seeding 'one-dimensional crystallization' of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
-
Jarrett JT & Lansbury PT Jr (1993) Seeding 'one-dimensional crystallization' of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73, 1055-1058.
-
(1993)
Cell
, vol.73
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury Jr, P.T.2
-
5
-
-
0025720634
-
Novel properties and biology of scrapie prions
-
Prusiner SB (1991) Novel properties and biology of scrapie prions. Curr Top Microbiol Immunol 172, 233-257.
-
(1991)
Curr Top Microbiol Immunol
, vol.172
, pp. 233-257
-
-
Prusiner, S.B.1
-
6
-
-
0027332116
-
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins
-
Pan KM, Baldwin M, Nguyen J, Gasset M, Serban A, Groth D, Mehlhorn I, Huang Z, Fletterick RJ, Cohen FE et al. (1993) Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc Natl Acad Sci USA 90, 10962-10966.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10962-10966
-
-
Pan, K.M.1
Baldwin, M.2
Nguyen, J.3
Gasset, M.4
Serban, A.5
Groth, D.6
Mehlhorn, I.7
Huang, Z.8
Fletterick, R.J.9
Cohen, F.E.10
-
7
-
-
0028962532
-
Prion protein gene variation among primates
-
Schatzl HM, Da Costa M, Taylor L, Cohen FE & Prusiner SB (1995) Prion protein gene variation among primates. J Mol Biol 245, 362-374.
-
(1995)
J Mol Biol
, vol.245
, pp. 362-374
-
-
Schatzl, H.M.1
Da Costa, M.2
Taylor, L.3
Cohen, F.E.4
Prusiner, S.B.5
-
8
-
-
0029962468
-
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
-
Vey M, Pilkuhn S, Wille H, Nixon R, DeArmond SJ, Smart EJ, Anderson RG, Taraboulos A & Prusiner SB (1996) Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proc Natl Acad Sci USA 93, 14945-14949.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14945-14949
-
-
Vey, M.1
Pilkuhn, S.2
Wille, H.3
Nixon, R.4
DeArmond, S.J.5
Smart, E.J.6
Anderson, R.G.7
Taraboulos, A.8
Prusiner, S.B.9
-
9
-
-
0027534612
-
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
-
Stahl N, Baldwin MA, Teplow DB, Hood L, Gibson BW, Burlingame AL & Prusiner SB (1993) Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry 32, 1991-2002.
-
(1993)
Biochemistry
, vol.32
, pp. 1991-2002
-
-
Stahl, N.1
Baldwin, M.A.2
Teplow, D.B.3
Hood, L.4
Gibson, B.W.5
Burlingame, A.L.6
Prusiner, S.B.7
-
10
-
-
0034665847
-
Signal transduction through prion protein
-
Mouillet-Richard S, Ermonval M, Chebassier C, Laplanche JL, Lehmann S, Launay JM & Kellermann O (2000) Signal transduction through prion protein. Science 289, 1925-1928.
-
(2000)
Science
, vol.289
, pp. 1925-1928
-
-
Mouillet-Richard, S.1
Ermonval, M.2
Chebassier, C.3
Laplanche, J.L.4
Lehmann, S.5
Launay, J.M.6
Kellermann, O.7
-
11
-
-
0028883341
-
-
Hornshaw MP, McDermott JR & Candy JM (1995) Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein. Biochem Biophys Res Commun 207, 621-629.
-
Hornshaw MP, McDermott JR & Candy JM (1995) Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein. Biochem Biophys Res Commun 207, 621-629.
-
-
-
-
12
-
-
0034654304
-
Consequences of manganese replacement of copper for prion protein function and proteinase resistance
-
Brown DR, Hafiz F, Glasssmith LL, Wong BS, Jones IM, Clive C & Haswell SJ (2000) Consequences of manganese replacement of copper for prion protein function and proteinase resistance. EMBO J 19, 1180-1186.
-
(2000)
EMBO J
, vol.19
, pp. 1180-1186
-
-
Brown, D.R.1
Hafiz, F.2
Glasssmith, L.L.3
Wong, B.S.4
Jones, I.M.5
Clive, C.6
Haswell, S.J.7
-
13
-
-
0035902531
-
Location and properties of metal-binding sites on the human prion protein
-
Jackson GS, Murray I, Hosszu LL, Gibbs N, Waltho JP, Clarke AR & Collinge J (2001) Location and properties of metal-binding sites on the human prion protein. Proc Natl Acad Sci USA 98, 8531-8535.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8531-8535
-
-
Jackson, G.S.1
Murray, I.2
Hosszu, L.L.3
Gibbs, N.4
Waltho, J.P.5
Clarke, A.R.6
Collinge, J.7
-
14
-
-
29144443530
-
Recombinant prion protein does not possess SOD-1 activity
-
Jones S, Batchelor M, Bhelt D, Clarke AR, Collinge J & Jackson GS (2005) Recombinant prion protein does not possess SOD-1 activity. Biochem J 392, 309-312.
-
(2005)
Biochem J
, vol.392
, pp. 309-312
-
-
Jones, S.1
Batchelor, M.2
Bhelt, D.3
Clarke, A.R.4
Collinge, J.5
Jackson, G.S.6
-
15
-
-
0037965529
-
Prion protein selectively binds copper (II) ions
-
Stockel J, Safar J, Wallace AC, Cohen FE & Prusiner SB (1998) Prion protein selectively binds copper (II) ions. Biochemistry 37, 7185-7193.
-
(1998)
Biochemistry
, vol.37
, pp. 7185-7193
-
-
Stockel, J.1
Safar, J.2
Wallace, A.C.3
Cohen, F.E.4
Prusiner, S.B.5
-
16
-
-
0033996803
-
Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry
-
Whittal RM, Ball HL, Cohen FE, Burlingame AL, Prusiner SB & Baldwin MA (2000) Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry. Protein Sci 9, 332-343.
-
(2000)
Protein Sci
, vol.9
, pp. 332-343
-
-
Whittal, R.M.1
Ball, H.L.2
Cohen, F.E.3
Burlingame, A.L.4
Prusiner, S.B.5
Baldwin, M.A.6
-
17
-
-
0032169565
-
Prion protein expression and superoxide dismutase activity
-
Brown DR & Besinger A (1998) Prion protein expression and superoxide dismutase activity. Biochem J 334, 423-429.
-
(1998)
Biochem J
, vol.334
, pp. 423-429
-
-
Brown, D.R.1
Besinger, A.2
-
18
-
-
0036798415
-
Copper-dependent functions for the prion protein
-
Brown DR & Sassoon J (2002) Copper-dependent functions for the prion protein. Mol Biotechnol 22, 165-178.
-
(2002)
Mol Biotechnol
, vol.22
, pp. 165-178
-
-
Brown, D.R.1
Sassoon, J.2
-
19
-
-
0035873869
-
Imbalance of antioxidant defense in mice lacking cellular prion protein
-
Klamt F, Dal-Pizzol F, Conte da Frota MJ, Walz R, Andrades ME, da Silva EG, Brentani RR, Izquierdo I & Fonseca Moreira JC (2001) Imbalance of antioxidant defense in mice lacking cellular prion protein. Free Radic Biol Med 30, 1137-1144.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 1137-1144
-
-
Klamt, F.1
Dal-Pizzol, F.2
Conte da Frota, M.J.3
Walz, R.4
Andrades, M.E.5
da Silva, E.G.6
Brentani, R.R.7
Izquierdo, I.8
Fonseca Moreira, J.C.9
-
20
-
-
0034764599
-
Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities
-
Wong BS, Brown DR, Pan T, Whiteman M, Liu T, Bu X, Li R, Gambetti P, Olesik J, Rubenstein R & Sy MS (2001) Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities. J Neurochem 79, 689-698.
-
(2001)
J Neurochem
, vol.79
, pp. 689-698
-
-
Wong, B.S.1
Brown, D.R.2
Pan, T.3
Whiteman, M.4
Liu, T.5
Bu, X.6
Li, R.7
Gambetti, P.8
Olesik, J.9
Rubenstein, R.10
Sy, M.S.11
-
21
-
-
0032724766
-
Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity
-
White AR, Collins SJ, Maher F, Jobling MF, Stewart LR, Thyer JM, Beyreuther K, Masters CL & Cappai R (1999) Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity. Am J Pathol 155, 1723-1730.
-
(1999)
Am J Pathol
, vol.155
, pp. 1723-1730
-
-
White, A.R.1
Collins, S.J.2
Maher, F.3
Jobling, M.F.4
Stewart, L.R.5
Thyer, J.M.6
Beyreuther, K.7
Masters, C.L.8
Cappai, R.9
-
22
-
-
0031194455
-
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity
-
Brown DR, Schulz-Schaeffer WJ, Schmidt B & Kretzschmar HA (1997) Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol 146, 104-112.
-
(1997)
Exp Neurol
, vol.146
, pp. 104-112
-
-
Brown, D.R.1
Schulz-Schaeffer, W.J.2
Schmidt, B.3
Kretzschmar, H.A.4
-
23
-
-
0033571055
-
Normal prion protein has an activity like that of superoxide dismutase
-
Brown DR, Wong BS, Hafiz F, Clive C, Haswell SJ & Jones IM (1999) Normal prion protein has an activity like that of superoxide dismutase. Biochem J 344 Part 1, 1-5.
-
(1999)
Biochem J
, vol.344
, Issue.PART 1
, pp. 1-5
-
-
Brown, D.R.1
Wong, B.S.2
Hafiz, F.3
Clive, C.4
Haswell, S.J.5
Jones, I.M.6
-
24
-
-
0141717118
-
No superoxide dismutase activity of cellular prion protein in vivo
-
Hutter G, Heppner FL & Aguzzi A (2003) No superoxide dismutase activity of cellular prion protein in vivo. Biol Chem 384, 1279-1285.
-
(2003)
Biol Chem
, vol.384
, pp. 1279-1285
-
-
Hutter, G.1
Heppner, F.L.2
Aguzzi, A.3
-
25
-
-
0034678023
-
Brain copper content and cuproenzyme activity do not vary with prion protein expression level
-
Waggoner DJ, Drisaldi B, Bartnikas TB, Casareno RL, Prohaska JR, Gitlin JD & Harris DA (2000) Brain copper content and cuproenzyme activity do not vary with prion protein expression level. J Biol Chem 275, 7455-7458.
-
(2000)
J Biol Chem
, vol.275
, pp. 7455-7458
-
-
Waggoner, D.J.1
Drisaldi, B.2
Bartnikas, T.B.3
Casareno, R.L.4
Prohaska, J.R.5
Gitlin, J.D.6
Harris, D.A.7
-
26
-
-
10644280708
-
Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease
-
Treiber C, Simons A, Strauss M, Hafner M, Cappai R, Bayer TA & Multhaup G (2004) Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease. J Biol Chem 279, 51958-51964.
-
(2004)
J Biol Chem
, vol.279
, pp. 51958-51964
-
-
Treiber, C.1
Simons, A.2
Strauss, M.3
Hafner, M.4
Cappai, R.5
Bayer, T.A.6
Multhaup, G.7
-
27
-
-
17844392850
-
Intracellular re-routing of prion protein prevents propagation of PrP (Sc) and delays onset of prion disease
-
Gilch S, Winklhofer KF, Groschup MH, Nunziante M, Lucassen R, Spielhaupter C, Muranyi W, Riesner D, Tatzelt J & Schatzl HM (2001) Intracellular re-routing of prion protein prevents propagation of PrP (Sc) and delays onset of prion disease. EMBO J 20, 3957-3966.
-
(2001)
EMBO J
, vol.20
, pp. 3957-3966
-
-
Gilch, S.1
Winklhofer, K.F.2
Groschup, M.H.3
Nunziante, M.4
Lucassen, R.5
Spielhaupter, C.6
Muranyi, W.7
Riesner, D.8
Tatzelt, J.9
Schatzl, H.M.10
-
28
-
-
0038159514
-
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation
-
Drisaldi B, Stewart RS, Adles C, Stewart LR, Quaglio E, Biasini E, Fioriti L, Chiesa R & Harris DA (2003) Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation. J Biol Chem 278, 21732-21743.
-
(2003)
J Biol Chem
, vol.278
, pp. 21732-21743
-
-
Drisaldi, B.1
Stewart, R.S.2
Adles, C.3
Stewart, L.R.4
Quaglio, E.5
Biasini, E.6
Fioriti, L.7
Chiesa, R.8
Harris, D.A.9
-
29
-
-
0035158658
-
A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic reticulum
-
Stewart RS, Drisaldi B & Harris DA (2001) A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic reticulum. Mol Biol Cell 12, 881-889.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 881-889
-
-
Stewart, R.S.1
Drisaldi, B.2
Harris, D.A.3
-
31
-
-
33746932518
-
Activation of superoxide dismutases: Putting the metal to the pedal
-
Culotta VC, Yang M & O'Halloran TV (2006) Activation of superoxide dismutases: putting the metal to the pedal. Biochim Biophys Acta 1763, 747-758.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 747-758
-
-
Culotta, V.C.1
Yang, M.2
O'Halloran, T.V.3
-
32
-
-
0015848053
-
Isozymes of superoxide dismutase from wheat germ
-
Beauchamp CO & Fridovich I (1973) Isozymes of superoxide dismutase from wheat germ. Biochim Biophys Acta 317, 50-64.
-
(1973)
Biochim Biophys Acta
, vol.317
, pp. 50-64
-
-
Beauchamp, C.O.1
Fridovich, I.2
-
33
-
-
33744766845
-
Effect of copper and manganese on the de novo generation of protease-resistant prion protein in yeast cells
-
Treiber C, Simons A & Multhaup G (2006) Effect of copper and manganese on the de novo generation of protease-resistant prion protein in yeast cells. Biochemistry 45, 6674-6680.
-
(2006)
Biochemistry
, vol.45
, pp. 6674-6680
-
-
Treiber, C.1
Simons, A.2
Multhaup, G.3
-
34
-
-
0028840671
-
The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP
-
Schroder S, Schimmoller F, Singer-Kruger B & Riezman H (1995) The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP. J Cell Biol 131, 895-912.
-
(1995)
J Cell Biol
, vol.131
, pp. 895-912
-
-
Schroder, S.1
Schimmoller, F.2
Singer-Kruger, B.3
Riezman, H.4
-
35
-
-
0035851122
-
A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage
-
Sturtz LA, Diekert K, Jensen LT, Lill R & Culotta VC (2001) A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage. J Biol Chem 276, 38084-38089.
-
(2001)
J Biol Chem
, vol.276
, pp. 38084-38089
-
-
Sturtz, L.A.1
Diekert, K.2
Jensen, L.T.3
Lill, R.4
Culotta, V.C.5
-
36
-
-
12844250715
-
PrP cooperates with STI1 to regulate SOD activity in PrP-deficient neuronal cell line
-
Sakudo A, Lee DC, Li S, Nakamura T, Matsumoto Y, Saeki K, Itohara S, Ikuta K & Onodera T (2005) PrP cooperates with STI1 to regulate SOD activity in PrP-deficient neuronal cell line. Biochem Biophys Res Commun 328, 14-19.
-
(2005)
Biochem Biophys Res Commun
, vol.328
, pp. 14-19
-
-
Sakudo, A.1
Lee, D.C.2
Li, S.3
Nakamura, T.4
Matsumoto, Y.5
Saeki, K.6
Itohara, S.7
Ikuta, K.8
Onodera, T.9
|