-
1
-
-
84893754725
-
-
2nd ed, C. G. Wermuth Ed, pp, Academic Press, London
-
nd ed., C. G. Wermuth (Ed.), pp. 233-250, Academic Press, London (2003).
-
(2003)
The Practice of Medicinal Chemistry
, pp. 233-250
-
-
Mann, A.1
-
2
-
-
0027241298
-
-
For example, see: (a) U. Gerhard, M. S. Searle, D. H. Williams. Bioorg. Med. Chem. Lett. 3, 803 (1993) and refs. therein;
-
For example, see: (a) U. Gerhard, M. S. Searle, D. H. Williams. Bioorg. Med. Chem. Lett. 3, 803 (1993) and refs. therein;
-
-
-
-
3
-
-
0032400532
-
-
(b) A. R. Khan, J. C. Parrish, M. E. Fraser, W. W. Smith, P. A. Bartlett, M. N. G. James. Biochemistry 37, 16839 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 16839
-
-
Khan, A.R.1
Parrish, J.C.2
Fraser, M.E.3
Smith, W.W.4
Bartlett, P.A.5
James, M.N.G.6
-
4
-
-
0028340743
-
-
For some examples, see: a
-
For some examples, see: (a) B. P. Morgan, D. R. Holland, B. W. Matthews, P. A. Bartlett. J. Am. Chem. Soc. 116, 3251 (1994);
-
(1994)
J. Am. Chem. Soc
, vol.116
, pp. 3251
-
-
Morgan, B.P.1
Holland, D.R.2
Matthews, B.W.3
Bartlett, P.A.4
-
5
-
-
0033602525
-
-
(b) P. Ettmayer, D. France, J. Gounarides, M. Jarosinski, M. S. Martin, J. M. Rondeau, M. Sabio, S. Topiol, B. Weidmann, M. Zurini, K. W Bair. J. Med. Chem. 42, 971 (1999);
-
(1999)
J. Med. Chem
, vol.42
, pp. 971
-
-
Ettmayer, P.1
France, D.2
Gounarides, J.3
Jarosinski, M.4
Martin, M.S.5
Rondeau, J.M.6
Sabio, M.7
Topiol, S.8
Weidmann, B.9
Zurini, M.10
Bair, K.W.11
-
6
-
-
0037471233
-
-
(c) Y. S. Tsantrizos, G. Bolger, P. Bonneau, D. R. Cameron, N. Goudreau, G. Kukolj, S. R. LaPlante, M. Llinas-Brunet, H. Nar, D. Lamarre. Angew. Chem., Int. Ed. 42, 1356 (2003).
-
(2003)
Angew. Chem., Int. Ed
, vol.42
, pp. 1356
-
-
Tsantrizos, Y.S.1
Bolger, G.2
Bonneau, P.3
Cameron, D.R.4
Goudreau, N.5
Kukolj, G.6
LaPlante, S.R.7
Llinas-Brunet, M.8
Nar, H.9
Lamarre, D.10
-
8
-
-
0001080522
-
-
For a leading reference, see
-
For a leading reference, see: M. P. Doyle, R. E. Austin, A. S. Bailey, M. P. Dwyer, A. B. Dyatkin, A. V. Kalinin, M. M. Y. Kwan, S. Liras, C. J. Oalmann, R. J. Pieters, M. N. Protopopova, C. E. Raab, G. H. P. Roos, Q.-L. Zhou, S. F. Martin. J. Am. Chem. Soc. 117, 5763 (1995).
-
(1995)
J. Am. Chem. Soc
, vol.117
, pp. 5763
-
-
Doyle, M.P.1
Austin, R.E.2
Bailey, A.S.3
Dwyer, M.P.4
Dyatkin, A.B.5
Kalinin, A.V.6
Kwan, M.M.Y.7
Liras, S.8
Oalmann, C.J.9
Pieters, R.J.10
Protopopova, M.N.11
Raab, C.E.12
Roos, G.H.P.13
Zhou, Q.-L.14
Martin, S.F.15
-
9
-
-
0026642037
-
-
S. F. Martin, R. E. Austin, C. J. Oalmann, W. R. Baker, S. L. Condon, E. deLara, S. H. Rosenberg, K. P. Spina, H. H. Stein, J. Cohen, H. D. Kleinen. J. Med. Chem. 35, 1710 (1992).
-
(1992)
J. Med. Chem
, vol.35
, pp. 1710
-
-
Martin, S.F.1
Austin, R.E.2
Oalmann, C.J.3
Baker, W.R.4
Condon, S.L.5
deLara, E.6
Rosenberg, S.H.7
Spina, K.P.8
Stein, H.H.9
Cohen, J.10
Kleinen, H.D.11
-
10
-
-
15144354436
-
-
S. F. Martin, G. O. Dorsey, T. Gane, M. C. Hillier, H. Kessler, M. Baur, B. Matha, J. W. Erickson, T. N. Bhat, S. Munshi, S. V. Gulnick, I. A. Topol. J. Med. Chem. 41, 1581 (1998).
-
(1998)
J. Med. Chem
, vol.41
, pp. 1581
-
-
Martin, S.F.1
Dorsey, G.O.2
Gane, T.3
Hillier, M.C.4
Kessler, H.5
Baur, M.6
Matha, B.7
Erickson, J.W.8
Bhat, T.N.9
Munshi, S.10
Gulnick, S.V.11
Topol, I.A.12
-
14
-
-
0037450487
-
-
H. R. Plake, T. B. Sundberg, A. R. Woodward, S. F. Martin. Tetrahedron Lett. 44, 1571 (2003).
-
(2003)
Tetrahedron Lett
, vol.44
, pp. 1571
-
-
Plake, H.R.1
Sundberg, T.B.2
Woodward, A.R.3
Martin, S.F.4
-
15
-
-
0037116524
-
-
J. P. Davidson, O. Lubman, T. Rose, G. Waksman, S. F. Martin. J. Am. Chem. Soc. 124, 205 (2002).
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 205
-
-
Davidson, J.P.1
Lubman, O.2
Rose, T.3
Waksman, G.4
Martin, S.F.5
-
17
-
-
0027409064
-
-
G. Waksman, S. E. Shoelson, N. Pant, D. Cowburn, J. Kuriyan. Cell 72, 779 (1993).
-
(1993)
Cell
, vol.72
, pp. 779
-
-
Waksman, G.1
Shoelson, S.E.2
Pant, N.3
Cowburn, D.4
Kuriyan, J.5
-
18
-
-
33746878979
-
-
A. P. Benfield, M. G. Teresk, H. R. Plake, J. E. DeLorbe, L. E. Millspaugh, S. F. Martin. Angew. Chem., Int. Ed. 45, 6830 (2006).
-
(2006)
Angew. Chem., Int. Ed
, vol.45
, pp. 6830
-
-
Benfield, A.P.1
Teresk, M.G.2
Plake, H.R.3
DeLorbe, J.E.4
Millspaugh, L.E.5
Martin, S.F.6
-
19
-
-
0036304080
-
-
P. Nioche, W.-Q. Liu, I. Broutin, F. Charbonnier, M.-T. Latreille, M. Vidal, B. Roques, C. Garbay, A. Ducruix. J. Mol. Biol. 315, 1167 (2002).
-
(2002)
J. Mol. Biol
, vol.315
, pp. 1167
-
-
Nioche, P.1
Liu, W.-Q.2
Broutin, I.3
Charbonnier, F.4
Latreille, M.-T.5
Vidal, M.6
Roques, B.7
Garbay, C.8
Ducruix, A.9
-
20
-
-
10944261243
-
-
For a discussion of effects of complexation upon changes in protein flexibility, see
-
For a discussion of effects of complexation upon changes in protein flexibility, see: D. H. Williams, E. Stephens, D. P. O'Brien, M. Zhou. Angew. Chem., Int. Ed. 43, 6596 (2004).
-
(2004)
Angew. Chem., Int. Ed
, vol.43
, pp. 6596
-
-
Williams, D.H.1
Stephens, E.2
O'Brien, D.P.3
Zhou, M.4
-
21
-
-
24744465619
-
-
For a recent discussion of using B-factors to compare protein flexibility in protein-ligand complexes, see: C.-Y. Yang, R. Wang, S. Wang. J. Med. Chem. 48, 5648 2005
-
For a recent discussion of using B-factors to compare protein flexibility in protein-ligand complexes, see: C.-Y. Yang, R. Wang, S. Wang. J. Med. Chem. 48, 5648 (2005).
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